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Chapeau
Emilie Chapeau, San Diego, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110067126 | GAB1 INVOLVEMENT IN GLUCOSE HOMEOSTASIS REGULATION BY HEPATOCYTES - The invention is directed to the regulation of glucose homeostasis by modulating the activity of Grb2-associated binder 1 (Gab1) in hepatocytes. This invention also provides for a method for identifying compounds capable of modulating the glucose homeostasis regulatory activity of Gab1. In one aspect, the invention provides a method for identifying a compound that can effectively modulate glucose homeostasis wherein Gab1 mediated MapK activity indicates that the candidate compound is an effective compound that modulates glucose homeostasis. In another aspect, the invention provides a method for identifying a compound that can effectively modulate the glucose homeostasis regulating activity of Gab1 wherein MAPK is activated to phosphorylate Serine residue 612 of IRS-1, indicating that the candidate compound is an effective compound that modulates glucose homeostasis. In another aspect of the invention is provided a method for diagnosing Gab1 related disorders. | 03-17-2011 |
Loren S. Chapeau, Forest Lake, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20090054949 | LEAD BODY CONSTRUCTIONS FOR IMPLANTABLE MEDICAL ELECTRICAL LEADS - A lead body of an implantable medical electrical lead includes a first filler and a second filler, each extending within a proximal portion thereof. The first filler may have a stiffness that is less than that of the second filler, and may surround and isolate a plurality of conductors which are coupled to a connector terminal of the lead, which connector terminal extends proximally from a proximal end of the lead body. The second filler extends along a limited length, alongside the first filler, wherein the limited length extends distally from the connector terminal; the second filler may further extend into the connector terminal. | 02-26-2009 |
Sébastien Chapeau, Nice FR
| Patent application number | Description | Published |
|---|---|---|
| 20100100282 | STRATEGY METHOD FOR REDUCING ENERGY CONSUMPTION OF A MOTOR VEHICLE - A method for reducing energy consumption of a motor vehicle having a power steering system including a electro-pump device (GEP) and for establishing set speeds of the electro-pump device depending on parameters of the operation of the vehicle, intended to be applied to the electro-pump device during a normal operating mode. At least one additional specific operating mode is defined, during which the speed of the electro-pump device is reduced to a level where the driver does not yet experience discomfort during driving and applies to the electro-pump device suitable set speeds when the vehicle operates according to the specific operating mode. | 04-22-2010 |
Sébastien Chapeau, Nice FR
| Patent application number | Description | Published |
|---|---|---|
| 20100100282 | STRATEGY METHOD FOR REDUCING ENERGY CONSUMPTION OF A MOTOR VEHICLE - A method for reducing energy consumption of a motor vehicle having a power steering system including a electro-pump device (GEP) and for establishing set speeds of the electro-pump device depending on parameters of the operation of the vehicle, intended to be applied to the electro-pump device during a normal operating mode. At least one additional specific operating mode is defined, during which the speed of the electro-pump device is reduced to a level where the driver does not yet experience discomfort during driving and applies to the electro-pump device suitable set speeds when the vehicle operates according to the specific operating mode. | 04-22-2010 |
Vincent Chapeau, Seraing BE
| Patent application number | Description | Published |
|---|---|---|
| 20080261325 | Method and Device for Dispensing Dry Powders - The inventive method for dispersing a dry powder sample ( | 10-23-2008 |
| 20110120368 | METHOD AND DEVICE FOR DISPERSING DRY POWDERS - A device for dispersing a sample of dry powder onto a surface in a dispersion chamber. The device includes a dispersion chamber situated in an environment, and a pressure source that provides a pressure difference between the environment and an inside of the dispersion chamber. The surface is positioned in the dispersion chamber. The sample of dry powder is introduced into the dispersion chamber through a membrane that is interposed between the environment and the inside of the dispersion chamber and on which the sample is disposed. The membrane is rupturable so as to open into the dispersion chamber when a predetermined pressure difference across the membrane is exceeded. This permits entry of a fluid in the environment through the ruptured membrane, and movement of the dry powder sample in an evenly dispersed manner without producing an ordered movement of powder grains in the dispersion chamber. | 05-26-2011 |