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Chanyong Brian

Chanyong Brian Lee, Camarillo, CA US

Patent application numberDescriptionPublished
20100236340AUTOMATABLE ASEPTIC SAMPLE WITHDRAWAL SYSTEM - An aseptic sampling system includes substantially sealed sampling lines connecting one or more sample container to a vessel containing the fluid to be sampled. A flow control system includes valves and/or clamps placed strategically along the sampling lines and filtered vent lines are provided at strategic locations relative to a reversible fluid pump in communication with the sampling lines. The clamps are selectively actuated, the vent lines are selectively opened or closed, and the pump is operated in a forward or reverse direction to permit a volume of sample fluid to be drawn from the vessel and into a sample container and to permit fluid to be purged from the sampling lines either into the sample container or back into the vessel. Thus, sampling and purging can be accomplished without opening the system to potentially contaminating agents and without wasting or having to properly dispose the fluid.09-23-2010

Chanyong Brian Lee, Newbury Park, CA US

Patent application numberDescriptionPublished
20090269849Bioreactor Apparatus - A bioreactor includes a fluid containment vessel and a rotating mixing element including radial inflow elements configured to direction fluid radially inwardly of the mixing element and axial out flow elements configured to redirect the radial inward flow in an axial direction. Both the vessel and the mixing element are made from plastic and the vessel comprises a flexible bag supported by a rigid housing. In one embodiment, the mixing element is pneumatically driven by the buoyancy of gas introduced into the vessel and trapped within gas entrapment cups formed on the periphery of the mixing element. As the volumetric capacity of the bioreactor increases, the ratio of the diameter of the mixing element to the width of the vessel decreases, and a gap defined between the bottom of the mixing element and the bottom of the vessel increase.10-29-2009

Chanyong Brian Lee, Thousand Oaks, CA US

Patent application numberDescriptionPublished
20080274452Process For Large Scale Production Of Plasmid Dna By E.Coli Fermentation - The present invention relates generally to a method for increasing the yield of plasmid DNA production. The method includes the steps of selecting a highly productive clonal subtype of a strain of 11-06-2008