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Chang, PA
Belinda Ying-Chieh Chang, Pittsburgh, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20100274889 | AUTOMATED FEED READER INDEXING - An incoming web feed received from a web feed document server is monitored for changes associated with a web feed document. A change associated with the web feed document is determined to have occurred. A priority is assigned to the change associated with the web feed document based upon a ranking criterion. The change associated with the web feed document is stored with the assigned priority to a memory. This abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract. | 10-28-2010 |
Chang Chang, Philadelphia, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20080318247 | Biomarker for cardiac transplant rejection - The invention provides a method of diagnosing a disease or disorder featuring an abnormal level of a ring-containing molecule in a tissue. In one embodiment, a method of diagnosing organ transplant rejection is provided. | 12-25-2008 |
Chien-Hsing Ken Chang, Downington, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090240037 | HUMANIZED ANTIBODIES AND METHODS OF HUMANIZING ANTIBODIES - Humanized, chimeric and human anti-CD20 antibodies and CD20 antibody fusion proteins that bind to a human B cell marker, referred to as CD20, which are useful for the treatment and diagnosis of B-cell disorders, such as B-cell malignancies and autoimmune diseases, and methods of treatment and diagnosis are disclosed. Methods of making the humanized, chimeric and human anti-CD20 antibodies are disclosed. A humanized anti-HSG (histamine-succinyl-glycyl) monoclonal antibody designated h679 which binds with high affinity to molecules containing the moiety histamine-succinyl-glycyl (HSG), and methods of making the humanized anti-HSG antibody also are disclosed. | 09-24-2009 |
Chien-Neng Chang, Collegeville, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090010884 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF PREVENTING, TREATING, OR INHIBITING INFLAMMATORY DISEASES, DISORDERS, OR CONDITIONS OF THE SKIN, AND DISEASES, DISORDERS, OR CONDITIONS ASSOCIATED WITH COLLAGEN DEPLETION - The present invention provides compositions and methods for preventing, treating, or inhibiting inflammatory diseases, disorders, or conditions of the skin, and diseases, disorders, or conditions associated with collagen depletion using one or more estrogenic agents. | 01-08-2009 |
Frank N. Chang, Dresher, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20110031122 | METHOD FOR DETECTING DISEASE MARKERS - Disease specific markers, in particular cancer markers, can be detected by electrophoretically separating proteins and protein complexes from a biological sample on a protein binding polymeric membrane in a low conductivity, water-miscible organic solvent buffer. Electrophoretic separation profiles representing different diseases can be produced, and used in the diagnosis or prognosis of these diseases. | 02-10-2011 |
Hao Chang, Lansdale, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20100062376 | Method and apparatus for thermal development with a conformable support - The present invention provides a method and apparatus for forming a printing form from a photosensitive element to form a relief pattern. The method and apparatus thermally develop the photosensitive element by heating a composition layer of the element to cause a portion of the layer to liquefy and providing a development medium to the element to remove the liquefied composition. A conformable layer is disposed between the photosensitive element and a base support, which improves the compressibility and the contact between the photosensitive element and the development medium. The method and apparatus improve the efficiency of the removal of liquefied portions from the photosensitive element and the uniformity of the relief pattern formed. | 03-11-2010 |
Hsiao-Lan Chang, Wayne, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20120122660 | OXIDATION CATALYST - An oxidation catalyst comprises an extruded solid body comprising: 10-95% by weight of at least one binder/matrix component; 5-90% by weight of a zeolitic molecular sieve, a non-zeolitic molecular sieve or a mixture of any two or more thereof; and 0-80% by weight optionally stabilised ceria, which catalyst comprising at least one precious metal and optionally at least one non-precious metal, wherein: (i) a majority of the at least one precious metal is located at a surface of the extruded solid body; (ii) the at least one precious metal is carried in one or more coating layer(s) on a surface; (iii) at least one metal is present throughout the extruded solid body and in a higher concentration at a surface; (iv) at least one metal is present throughout the extruded solid body and in a coating layer(s) on a surface; or (v) a combination of (ii) and (iii). | 05-17-2012 |
Jin-Chung Chang, Garnet Valley, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20110178206 | FLAME RETARDANT POLY(TRIMETHYLENE TEREPHTHALATE) COMPOSITION - Improved flame retardant polytrimethylene terephthalate compositions are provided by including a bis(diphenyl phosphate) flame retardant additive. | 07-21-2011 |
Jing C. Chang, Boothwyn, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090047857 | STAPLE FIBERS AND PROCESSES FOR MAKING SAME - Improved staple fibers and processes for producing them are provided. The processes are particularly useful for forming staple fibers from poly(trimethylene terephthalate), especially carpet staple fibers. The processes include prewetting undrawn yarns and drawing the fibers under wet and warm conditions, thermo-fixing the texture, and drying at relatively low temperatures. Fibers produced according to the processes disclosed herein have improved properties and reduced brittleness as compared to fibers prepared using conventional processes. | 02-19-2009 |
| 20100105841 | POLY(TRIMETHYLENE TEREPHTHALATE)/POLY(ALPHA-HYDROXY ACID) BICONSTITUENT FILAMENTS - This invention relates to poly(trimethylene terephthalate)/poly(alpha-hydroxy acid) biconstituent filaments, methods for making the same and end uses thereof. | 04-29-2010 |
Jing-Chung Chang, Boothwyn, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20100159184 | POLY-TRIMETHYLENE TEREPHTHALATE SOLID CORE FIBRILLATION-RESISTANT FILAMENT HAVING A SUBSTANTIALLY TRIANGULAR CROSS SECTION, A SPINNERET FOR PRODUCING THE FILAMENT, AND A CARPET MADE THEREFROM - In a first aspect the invention is a solid core fibrillation-resistant, synthetic polymeric filament having three substantially equal length convex sides. The sides through substantially rounded tips centered by a distance “a” from the axis of the filament. Each rounded tip has a radius substantially equal to a length “b”. Each tip lies on a circumscribed circle having a radius substantially equal to a length (a+b) and the midpoint of each side lies on an inscribed circle having a radius substantially equal to a length “c”. The filament has a denier-per-filament in the range 10<“dpf”<35; the distance “a” lies in the range 0.00025 inches (6 micrometers)<“a”<0.004 inches (102 micrometers); the distance “b” lies in the range from 0.00008 inches (2 micrometers)<“b”<0.001 inches (24 micrometers); the distance “c” lies in the range from 0.0003 inches (8 micrometers)<“c”<0.0025 inches (64 micrometers); and the modification ratio (“MR”) lies in the range from about 1.1<“MR”< about 2.0. | 06-24-2010 |
| 20100159186 | POLY-TRIMETHYLENE TEREPHTHALATE SOLID CORE FIBRILLATION-RESISTANT FILAMENT HAVING A SUBSTANTIALLY TRIANGULAR CROSS SECTION, A SPINNERET FOR PRODUCING THE FILAMENT, AND A CARPET MADE THEREFROM - In a first aspect the invention is a solid core fibrillation-resistant, synthetic polymeric filament having three substantially equal length convex sides. The sides through substantially rounded tips centered by a distance “a” from the axis of the filament. Each rounded tip has a radius substantially equal to a length “b”. Each tip lies on a circumscribed circle having a radius substantially equal to a length (a+b) and the midpoint of each side lies on an inscribed circle having a radius substantially equal to a length “c”. The filament has a denier-per-filament in the range 10<“dpf”<35; the distance “a” lies in the range 0.00025 inches (6 micrometers)<“a”<0.004 inches (102 micrometers); the distance “b” lies in the range from 0.00008 inches (2 micrometers)<“b”<0.001 inches (24 micrometers); the distance “c” lies in the range from 0.0003 inches (8 micrometers)<“c”<0.0025 inches (64 micrometers); and the modification ratio (“MR”) lies in the range from about 1.1<“MR”| 06-24-2010 | |
Jing-Chung Chang, Garnet Valley, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090043016 | FLAME RETARDANT POLYTRIMETHYLENE TEREPHTHALATE COMPOSITION - Improved flame retardant polytrimethylene terephthalate compositions are provided by including a fluorinated sulfonate salt as a flame retardant additive. | 02-12-2009 |
| 20090043017 | FLAME RETARDANT POLYTRIMETHYLENE TEREPHTHALATE COMPOSITION - Improved flame retardant polytrimethylene terephthalate compositions are provided by including a perfluorinated sulfonate salt as a flame retardant additive. | 02-12-2009 |
| 20090043019 | FLAME RETARDANT POLYTRIMETHYLENE TEREPHTHALATE COMPOSITION - Improved flame retardant polytrimethylene terephthalate compositions are provided by including a brominated flame retardant additive. | 02-12-2009 |
| 20090043020 | FLAME RETARDANT POLYTRIMETHYLENE TEREPHTHALATE COMPOSITION - Improved flame retardant polytrimethylene terephthalate compositions are provided by including a melamine cyanurate flame retardant additive. | 02-12-2009 |
| 20090043021 | FLAME RETARDANT POLYTRIMETHYLENE TEREPHTHALATE COMPOSITION - Improved flame retardant polytrimethylene terephthalate compositions are provided by including a certain phosphorous compound as a flame retardant additive. | 02-12-2009 |
| 20110172329 | FLAME RETARDANT POLY(TRIMETHYLENE TEREPHTHALATE) COMPOSITION - Improved flame retardant polytrimethylene terephthalate compositions are provided by including a bis(diphenyl phosphate) flame retardant additive. | 07-14-2011 |
| 20110311759 | FLAME RETARDANT PERFORMANCE IN POLY (TRIMETHYLENE) TEREPHTHALATE - Poly(trimethylene terephthalate) compositions, and articles made therefrom, having improved flame retardancy are provided. The compositions can be used to make carpets that are suitable for installation where flame retardancy is desired. | 12-22-2011 |
Jinhong Chang, Chalfont, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20110189771 | Novel Imino Sugar Derivatives Demonstrate Potent Antiviral Activity and Reducted Toxicity - Imino sugars, such as deoxynojirimycin (DNJ), are glucose analogues that selectively inhibit cellular α-glucosidase I and II (enzymes that process N-linked glycans in glycoprotein) and exhibit broad spectrum antiviral activities against many enveloped viruses. Previously we have reported a novel DNJ derivative, OSL-95II, with antiviral activity and reduced cytotoxicity. In order to develop imino sugars with more potent antiviral activity as well as improved toxicity profile, OSL-95II was modified by diversifying the nitrogen linked alkylated side chain. The antiviral activities were initially tested in bovine viral diarrhea virus (BVDV) infected MDBK cells, yielding several imino sugar derivatives with novel structure and superior antiviral activity and toxicity profile. Furthermore, these new compounds were shown to be active against Dengue virus (DV) and West Nile virus (WNV) infection in BHK cells where potent anti-DV activity having submicromolar EC50 values and SI of greater than 900. These compounds represent a new generation of iminio sugars and their analogues, having application in the clinical treatment of infection of DV and other members of flaviviridae. | 08-04-2011 |
Kern K.n. Chang, Langhorne, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090174518 | Toroidal star-shaped transformer - A toroidal power transformer is disclosed. The toroidal power transformer comprises a circular core composed of plurality of laminated electrically conductive materials, a plurality of multi-layered first windings radially wound around the circular core, said winding arranged with an angular spacing of 2θ and a number of windings in each winding layer is less than a number of windings in each previous layer, a multi-layered second winding radially wound around the circular core covering a corresponding one of said plurality of first windings, wherein the layers of each of said second windings are arranged to form a substantially triangular cross-section; and an insulating layer between each of said first and section windings. | 07-09-2009 |
Kyong-Mi Chang, Bryn Mawr, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090305408 | Method for the rapid expansion of antigen specific t-cell - The present invention encompasses a method for expanding an antigen specific T cell from a population of cells. The method of the present invention comprises contacting a population of cells with an MHC restricted antigenic peptide, a cytokine and a co-stimulatory signal. The invention also encompasses compositions and kits comprising an antigen specific T cell. | 12-10-2009 |
Phillip F. Chang, Langhorne, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20110194418 | IDENTIFICATION OF A FAULT - An apparatus, method, and system are provided for determining a location of an error source. Equalization coefficients may be retrieved and an average period of time between localized peak amplitudes may be determined. The average period of time may be multiplied by a velocity of propagation associated with a communication channel to determine an approximate location of the error source. The equalization coefficients may correspond to the inverse of the frequency response associated with the communication channel and may be updated over time using replacement or combination (e.g., convolution) techniques. | 08-11-2011 |
| 20110194597 | MODULATION ANALYSIS AND DISTORTION IDENTIFICATION - An apparatus, method, computer readable medium, and system are provided to generate a symbol placement associated with a transmission scheme by transforming a retrieved set of equalization coefficients. Symbols included in the symbol placement may be analyzed and quantified in terms of their distance from a decision boundary. Symbols may be synthesized on an iterative basis in order to obtain visibility into the underlying performance of the transmission scheme over time. If equalization is unable to reduce a signal impairment below a threshold value within a predetermined amount of time, then a determination may be made that a non-linear distortion source is present in a network or communication system. Signals received from a plurality of user terminals may be compared with one another in order to determine a probable location or cause of the non-linear distortion. | 08-11-2011 |
| 20110197071 | Determining Response Signature Commonalities - An analyzer can obtain data regarding signal characteristics in each of multiple communication channels within an access network. The analyzer can use that data to create signatures corresponding to each of the multiple channels. Based on similarities between signatures, the analyzer may then identify clusters of signatures associated with devices that share channels or portions of channels. | 08-11-2011 |
| 20110243214 | INDUCING RESPONSE SIGNATURES IN A COMMUNICATION NETWORK - Methods and systems are provided in which a network induces different distortions in signals traversing different segments of the network. The distortions may be used to identify locations on the network of devices that transmit and receive the signals. The distortions may be reflected in equalization coefficients programmed into transmitting or receiving devices, which may be used to pre or post filter the signals to compensate for the distortions. | 10-06-2011 |
Robert C. Chang, Philadelphia, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20080261288 | Micro-Organ Device - A method for fabricating a micro-organ device comprises providing a microscale support having one or more microfluidic channels and one or more micro-chambers for housing a micro-organ and printing a micro-organ on the microscale support using a cell suspension in a syringe controlled by a computer-aided tissue engineering system, wherein the cell suspension comprises cells suspended in a solution containing a material that functions as a three-dimensional scaffold. The printing is performed with the computer-aided tissue engineering system according to a particular pattern. The micro-organ device comprises at least one micro-chamber each housing a micro-organ; and at least one microfluidic channel connected to the micro-chamber, wherein the micro-organ comprises cells arranged in a configuration that includes microscale spacing between portions of the cells to facilitate diffusion exchange between the cells and a medium supplied from the at least one microfluidic channel. | 10-23-2008 |
Ronald K. Chang, Oreland, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20100222355 | QUINOLIZIDINONE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS - The present invention is directed to spiropiperidine compounds of formula (I) which are M1 receptor positive allosteric modulators and that are useful in the treatment of diseases in which the M1 receptor is involved, such as Alzheimer's disease, schizophrenia, pain or sleep disorders. The invention is also directed to pharmaceutical compositions comprising the compounds, and to the use of the compounds and compositions in the treatment of diseases mediated by the M1 receptor. | 09-02-2010 |
| 20100324024 | Quinolizidinone M1 Receptor Positive Allosteric Modulators - The present invention is directed to compounds of formula (I) (I) which are M1 receptor positive allosteric modulators and that are useful in the treatment of diseases in which the M1 receptor is involved, such as Alzheimer's disease, schizophrenia, pain or sleep disorders. The invention is also directed to pharmaceutical compositions comprising the compounds, and to the use of the compounds and compositions in the treatment of diseases mediated by the M1 receptor. | 12-23-2010 |
| 20110046145 | Quinolizidinone M1 Receptor Positive Allosteric Modulators - The present invention is directed to compounds of formula (I) which are M1 receptor positive allosteric modulators and that are useful in the treatment of diseases in which the M1 receptor is involved, such as Alzheimer's disease, schizophrenia, pain or sleep disorders. The invention is also directed to pharmaceutical compositions comprising the compounds, and to the use of the compounds and compositions in the treatment of diseases mediated by the M1 receptor. | 02-24-2011 |
| 20110112077 | Quinolizidinone m1 Receptor Positive Allosteric Modulators - The present invention is directed to compounds of formula (I) which are M1 receptor positive allosteric modulators and that are useful in the treatment of diseases in which the M1 receptor is involved, such as Alzheimer's disease, schizophrenia, pain or sleep disorders. The invention is also directed to pharmaceutical compositions comprising the compounds, and to the use of the compounds and compositions in the treatment of diseases mediated by the M1 receptor. | 05-12-2011 |
Ronald K. Chang, Ambler, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20100197657 | 2-ARYL OR HETEROARYL INDOLE DERIVATIVES - The present invention provides 2-aryl or heteroaryl indole derivatives which are ASIC channel modulators, maceutical compositions containing such compounds, and methods of using them as therapeutic agents. | 08-05-2010 |
Susan C. Chang, Pittsburgh, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20110110652 | Active air heater - An active air heater is constructed to produce heat and to transfer heat to an air flow for heating a building. The active air heater comprises spaced apart fins; adjacent elements between the fins; and an electrical source directing an electrical current through the fins and the adjacent elements for heating the fins and the adjacent elements and the air flowing through the air flow passageways formed by the adjacent elements. The adjacent elements are porous, semi-conductor material having a roughness in its surfaces for enhancing the convective heat transfer between the material and the air flow. The active air heater may be rectangular or cylindrical. The porous, semi-conductor material includes carbon foams, ceramic foams, high temperature polymer foams, and low conductance alloy foams and the aforementioned materials in nano-material format. | 05-12-2011 |
Susan C. Chang, Canonsburg, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20100297421 | Blast Energy Mitigating Composite - A blast energy mitigating composite useful for protecting a surface or an object from a blast, shock waves, or stress waves caused by a sudden, violent release of energy is described. Certain configurations of the blast energy mitigating composite may include a energy mitigating units contained in an energy mitigating matrix. The energy mitigating units may comprise a porous energy mitigating material such as carbon foam. | 11-25-2010 |
Te Chang, West Chester, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20080230369 | Propylene oxide recovery process - Product propylene oxide in a reaction mixture resulting from the reaction of propylene, oxygen and hydrogen or from the reaction of propylene and hydrogen peroxide is separated from propylene and/or propane by extractive distillation using methanol and/or water extractive distillation solvent. | 09-25-2008 |
| 20080300417 | Slurry reaction system - The present invention provides a slurry reaction system wherein liquid reaction mixture containing catalyst fines is separated from catalyst particles of a size suitable for use in the slurry reaction in a first separation step and in a subsequent separation step the catalyst fines are separated from liquid reaction mixture. | 12-04-2008 |
| 20090247773 | Propylene oxide process - A process for making propylene oxide from propylene is disclosed. Propylene, hydrogen, and oxygen are reacted in a slurry comprising a catalyst and a solvent to produce a gaseous product stream and a liquid product stream. The gaseous product stream is contacted with an absorbent to produce a gas effluent and a liquid effluent. The gas effluent is recycled to the reaction step. | 10-01-2009 |
| 20090306416 | Propylene oxide process - A process for making propylene oxide from propylene is disclosed. The process comprises reacting propylene, oxygen, and hydrogen in the presence of a catalyst, a solvent, and a buffer to produce a reaction mixture comprising propylene oxide. Separation of light components from the reaction mixture gives a heavy residue comprising the buffer. The buffer is precipitated from the heavy residue by a precipitating agent. | 12-10-2009 |
| 20100056814 | PROPYLENE OXIDE PROCESS - A process for making propylene oxide from propylene is disclosed. The process comprises reacting propylene, oxygen, and hydrogen in the presence of a catalyst and a solvent to produce a reaction mixture comprising propylene oxide. Separation of propylene, oxygen, hydrogen, and propylene oxide from the reaction mixture results in a residual mixture comprising methanol. A portion of the residual mixture is recycled to the reaction. A portion of the residual mixture is distilled to generate a distilled methanol stream, which is recycled to the reaction. | 03-04-2010 |
Yuan Chang, Pittsburgh, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090068211 | IMMUNOGENICALLY-ENHANCED POLYPEPTIDES AND RELATED METHODS - Described herein are immunogenically-enhanced polypeptides, such as KSHV LANA1 polypeptides, related methods of eliciting an immune response to the polypeptides and related nucleotide sequences. Also described herein are novel polypeptides capable of inhibiting degradation and/or retarding synthesis of a protein when attached to or incorporated within that protein along with related methods and nucleotide sequences. | 03-12-2009 |
| 20110135598 | METHODS TO DIAGNOSE AND IMMUNIZE AGAINST THE VIRUS CAUSING HUMAN MERKEL CELL CARCINOMA - The present invention provides isolated or substantially purified polypeptides, nucleic acids, and virus-like particles (VLPs) derived from a Merkel cell carcinoma virus (MCV), which is a newly-discovered virus. The invention further provides monoclonal antibody molecules that bind to MCV polypeptides. The invention further provides diagnostic, prophylactic, and therapeutic methods relating to the identification, prevention, and treatment of MCV-related diseases. | 06-09-2011 |
Yuan Chang, Pittsburg, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20110311567 | Immunogenically-Enhanced Polypeptides and Related Methods - Described herein are immunogenically-enhanced polypeptides, such as KSHV LANA1 polypeptides, related methods of eliciting an immune response to the polypeptides and related nucleotide sequences. Also described herein are novel polypeptides capable of inhibiting degradation and/or retarding synthesis of a protein when attached to or incorporated within that protein along with related methods and nucleotide sequences. | 12-22-2011 |
Yuan Chang, Newtown Square, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20120019592 | Print head mounting and adjusting mechanism - An improved print head mounting and adjusting mechanism for inkjet printers. The mechanism include a bottom bracket and a base plate, the bottom bracket is installed on the base plate, the bottom bracket can be used for mounting print head, wherein said bottom bracket is supported by two stainless steel round shaft which is mounted on the base plate to provide accurate Y-axis movement and adjustment. Micrometer screw head is used as the adjustment mechanism for fine precision adjustment. The bottom bracket moves along a stainless steel round shaft to prevent deflection while adjusting. The print head and the adjustment mechanism are two separate parts, so exchanging or adjusting it will not damage the print heads. Remounting a print head requires a slight adjustment to reach the desired position reducing labor intensity and making for easier maintenance to the print heads. | 01-26-2012 |
