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Chang, GB

Chiwen Chang, Cambridge GB

Patent application numberDescriptionPublished
20100087378Compositions and Methods for Treating Diseases Associate with Angiogenesis and Inflammation - Pharmaceutical compositions and methods for treating diseases associated with angiogenesis and inflammation. The invention relates to a pharmaceutical composition that includes a therapeutically effective amount of sCD26 and/or a biologically active derivative thereof and a pharmaceutically acceptable carrier. The composition may further include a therapeutically effective amount of sFlt-1 and/or a biologically active derivative thereof Additionally, the invention relates to methods for treating a disease associated with and/or progresses by an inflammatory cytokine-associated inflammation and/or VEGF-associated angiogenesis.04-08-2010

Patent applications by Chiwen Chang, Cambridge GB

Simon Chang, Cambridge GB

Patent application numberDescriptionPublished
20100060501RAIL TO RAIL FLASH - An analogue to digital converter comprising: a first set comprising nodes defined by circuitry such that each node is at a respective voltage, the voltages on the nodes being in an orderly progression between the voltage of a first current source and the voltage of a first input node; a second set comprising nodes defined by circuitry such that each node is at a respective voltage, the voltages on the nodes being in an orderly progression between the voltage of a second current source and the voltage of a second input node; a plurality of comparators, each comparator being arranged to compare the voltage on a node in the first set with the voltage on a respective node in the second set; and a pair of switching devices arranged between the first current source and the first set of nodes, the first switching device of the pair connected so as to supply the current from the first current source to all said nodes in the first set, and the second switching device of the pair connected so as to supply the current from the first current source to a subset of said nodes in the first set which are closest in voltage to the voltage of the first input node; wherein control voltages of the first and second switching devices of the pair are set such that: (a) when the potential difference between the voltage at the first current source and the voltage at the first input node is greater than a predetermined potential difference the first switching device is in a first state and the current from the first current source flows through the first switching device; and (b) when the potential difference between the voltage at the first current source and the voltage at the first input node is less than the predetermined potential difference the first switching device is in a second state and the current from the first current source flows through the second switching device.03-11-2010
20110115662High Speed Low Voltage Flash - An analog-to-digital converter comprising: first and second sets of ordered nodes, each first node having a corresponding second node; for each first node, a respective first resistor and current source pair, the resistor of each pair being connected to a first converter input and the current source of each pair being coupled to the respective first node; for each second node, a respective second resistor and current source pair, the resistor of each pair being connected to a second converter input and the current source of each pair being coupled to the respective second node; and a plurality of first comparators, each first comparator having its first input connected to a first node and its second input connected to the corresponding second node; wherein each of the first resistor and current source pairs are configured so as to provide an orderly progression of voltages at the first nodes and each of the second resistor and current source pairs are configured so as to provide an orderly progression of voltages at the second nodes.05-19-2011

Patent applications by Simon Chang, Cambridge GB

Sophie Chang, London GB

Patent application numberDescriptionPublished
20090157797DATA DISTRIBUTION SYSTEM - A data processing system for distributing a package of data from a source to a plurality of data processing machines arranged in a plurality of sites. The data is transmitted from the source to the plurality of data processing machines by means of a multicast. At each site, a local data processing machine is designated as a site master; the other local data processing machines report missing data portions to the site master; and the site master consolidates reports of missing data portions, and requests missing data portions from the source. The source then transmits the missing data portions to the plurality of data processing machines by means of a further multicast. If the site master receives a report of missing data that the site master has stored locally, the site master provides that missing data to the local machines by means of a site multicast. Reports of missing data received by the source from site masters at different sites are consolidated at the source before the source transmits the missing data to the plurality of sites by means of the further multicast. If a local machine is missing data from the multicast from the source, and is not aware that a site master has been designated, that local machine broadcasts to machines at that site information indicating that a site master is required. If a site master is already designated, that site master notifies that local machine that it is the site master; but if no site master is already designated, an election process is instigated to designate one of the machines at that site as site master.06-18-2009
20100131785POWER MANAGEMENT OF COMPUTERS - A method of controlling power consumption in a computer uses a power management program installed on the computer to detect the identities of processes running on the computer which maintain the computer in a high power state in the absence of input activity. The program compares the identity of the or each process running on the computer with a set of identities of previously identified processes and causes the computer to adopt a low power state if the detected identity of a process, or the detected identities of all the processes, running on the computer is/are in the set of previously identified processes.05-27-2010
20110054846Monitoring the Performance of a Computer - A computer implemented method of monitoring the performance of a computer comprises monitoring the computer to determine the values of a plurality of activity metrics of the monitored computer. A weighted combination of functions of the determined values is calculated as a measure of performance of the monitored computer. The weighted combination may be a weighted combination of net values of activity metrics. In one embodiment, the net values are calculated as the said values of the plurality of activity metrics of the monitored computer excluding contributions to the values from the one or more predetermined activities. In another embodiment, the net values are calculated as follows. The total values of the respective activity metrics of the monitored computer are determined. The contribution(s) to the said total values of the said one or more predetermined activities are determined The said contribution(s) are subtracted from the said total values to provide net values. The weighted combination may be used to control power consumption or otherwise take action in relation to the computer.03-03-2011
20110055609Controlling the Power State of a Computer - A computer implemented method of controlling a computer comprises periodically determining the total value of at least one activity metric of the controlled computer. The contribution(s) to the said total value(s) of one or more predetermined activities are determined. In one embodiment, the said contribution(s) are subtracted from the said total value(s) to provide respective net value(s). The net values are compared with respective preset values and the power state of the computer is controlled in dependence on the comparison. The one or more predetermined activities may be identified using a predetermined data set. In another embodiment the net value of at least one activity metric of the monitored computer is a net value excluding contributions to the said value(s) from the said one or more predetermined activities identified from the said data set.03-03-2011
20110093588Monitoring the performance of a Computer - A computer implemented method of monitoring the performance of a computer comprises determining the value of an activity metric of the monitored computer. The contribution(s) to the said value of one or more predetermined activities is/are determined In one embodiment, the said contribution(s) are subtracted from the said total value to provide a net value representing a measure of the performance of the computer. A predetermined data set may be used to identify the one or more predetermined activities. In another embodiment, the value of at least one activity metric of the monitored computer is determined excluding contributions to that value from the said one or more predetermined activities identified from the said data set to provide a net value representing a measure of the performance of the computer. The net value may be used to control the power consumption of the computer.04-21-2011
20110161707POWER MANAGEMENT OF COMPUTERS - A method of controlling power consumption in a computer by detecting whether or not there is any user activity, and also the identity of each process running on the computer. The identity of each process running on the computer is compared with a set of identities of previously identified processes, these having been deemed to be processes for which it is desirable that the computer maintains a high power state. The computer adopts a low power state if all the detected identities of processes are not in the set of high power state processes or no user activity is detected. The low power state is a state in which the computer is able to service requests. The computer freely adopts any available higher power state if user activity is detected or a detected process is in the set of high power state processes. The power state selected may depend on workload.06-30-2011

Patent applications by Sophie Chang, London GB