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Chan, PA
Adam Chan, West Chester, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20110011210 | Process for making glycol ether compositions useful for metal recovery - Glycol ether compositions useful for metal recovery by froth flotation and processes for making the compositions are disclosed. In one process, dipropylene glycol methyl ether (DPM) is propoxylated to give a composition comprising 4 to 15 wt. % of DPM and at least 20 wt. % of tripropylene glycol methyl ether (TPM). In another process, the glycol ether composition is made from a distillation residue which comprises DPM, TPM, and a basic catalyst. Extraction of the residue with water to remove some of the basic catalyst is followed by propoxylated to give a composition which comprises less than 15 wt. % of DPM, at least 20 wt. % of TPM, and one or more PO-based glycols. In comparative froth tests, glycol ether compositions of the invention meet or exceed the performance of commercial frothers. | 01-20-2011 |
Anita Wai-Yin Chan, Wayne, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090023903 | PROCESS FOR THE PREPARATION OF TRIFLUOROALKYL-PHENYL AND HETEROCYCLIC SULFONAMIDES - A novel trifluoroacetylating agent, i.e., N-trifluoroacetylmorpholine, is described. This reagent is useful in the preparation of phenyl and heterocyclic sulfonamide compounds. Methods are therefore described for preparing sulfonamide compounds of the following structure, wherein R | 01-22-2009 |
| 20090023925 | N'-(2-HALOBENZYLIDENE)SULFONYLHYDRAZIDES AS INTERMEDIATES IN THE MANUFACTURE OF ARYLSULFONYLINDAZOLES - The present invention provides N′-(2-halobenzylidene)sulfonylhydrazides of formula I | 01-22-2009 |
| 20100016639 | PRODUCTION OF CHIRALLY PURE AMINO ALCOHOL INTERMEDIATES, DERIVATIVES THEREOF, AND USES THEREOF - A method of selectively preparing a chiral 2S-amino alcohol useful in preparation of an amide sulfonated or acylated with alkyl, substituted aryl or substituted heteroaryl is described. The method involves reacting a di-tert-butyl diazene-1,2-dicarboxylate with a (4S)-4-benzyl-3-[(S)-trifluoromethyl-alkyl substituted alkanoyl]-1,3-oxazolidin-2-one to afford a di-tert-butyl 1-(1S,2S)-([(4S)-4-benzyl-2-oxo-1,3-oxazolidine-3-yl]-carbonyl}-trifluoromethyl-alkyl substituted alkyl)hydrazine-1,2-dicarboxylate. This dicarboxylate is then reduced to yield di-tert-butyl 1-(1S,2S)-[trifluoromethyl-alkyl substituted alkyl]hydrazine-1-(hydroxymethyl)-1,2-dicarboxylate. The resulting product is deblocked with an acid to yield the acid addition salt of (2S,3S)-trifluoro-hydrazino-methyl alkan-1-ol. The acid addition salt of (2S,3S)-trifluoro-2-hydrazino-methyl alkan-1-ol is hydrogenated in the presence of a suitable metal catalyst to yield the amino alcohol (2S,3S)-2-amino-trifluoro-methyl alkan-1-ol HCl. | 01-21-2010 |
Edwin Chan, Downingtown, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20100324683 | INTERVERTEBRAL IMPLANT - An intervertebral implant that is configured to be inserted into an intervertebral space along a direction of insertion is provided. The intervertebral space is defined by a superior vertebral body and an inferior vertebral body that are opposed in a transverse direction. The intervertebral implant may include a body and a first keel. The body may have first and second opposing outer surfaces that are each configured to engage one of the superior and inferior vertebral bodies. The first keel may extend out from the first outer surface in an outward direction and may define a lateral width that increases with respect to an outward direction along the first keel such that an outer portion of the first keel is wider than an inner portion of the first keel. The lateral width may be substantially transverse to the insertion direction and the outward direction. | 12-23-2010 |
Edwin Chan, Fogelsville, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20110021965 | ADHESIVE ARTICLES - An adhesive article includes a biocompatible and at least partially biodegradable substrate having a surface; and a plurality of protrusions extending from the surface. The protrusions include a biocompatible and at least partially biodegradable material, and have an average height of less than approximately 1,000 micrometers. | 01-27-2011 |
Geoffrey Chan, King Of Prussia, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20110274697 | NOVEL USES - The present invention relates generally to the use of bendamustine in combination with an anti-CD20 antibody to treat cancer. | 11-10-2011 |
Helen M. Chan, Bethlehem, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20100144511 | MICROPOROUS CERAMICS AND METHODS OF MANUFACTURE - Inorganic microporous metal oxide materials, such as aluminum-based microporous ceramic materials, useful for loop heat pipes, insulators, thermal management devices, catalyst supports, substrates, and filters, among others. An example method of manufacture includes heating a mixture of alumina (Al | 06-10-2010 |
| 20110147703 | ABBREVIATED EPITAXIAL GROWTH MODE (AGM) METHOD FOR REDUCING COST AND IMPROVING QUALITY OF LEDs AND LASERS - The use of an abbreviated GaN growth mode on nano-patterned AGOG sapphire substrates, which utilizes a process of using 15 nm low temperature GaN buffer and bypassing etch-back and recovery processes during epitaxy, enables the growth of high-quality GaN template on nano-patterned AGOG sapphire. The GaN template grown on nano-patterned AGOG sapphire by employing abbreviated growth mode has two orders of magnitude lower threading dislocation density than that of conventional GaN template grown on planar sapphire. The use of abbreviated growth mode also leads to significant reduction in cost of the epitaxy. The growths and characteristics of InGaN quantum wells (QWs) light emitting diodes (LEDs) on both templates were compared. The InGaN QWs LEDs grown on the nano-patterned AGOG sapphire demonstrated at least a 24% enhancement of output power enhancement over that of LEDs grown on conventional GaN templates. | 06-23-2011 |
Sham-Yuen Chan, Malvern, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090036358 | Methods of preparing pharmaceutical compositions for treatment of factor Vlll associated disorders and methods of use - The invention concerns glycosylated proteins having human factor VIII activity. In a preferred embodiment, the protein is glycosylated with oligosaccharides that include an alpha-(2,6)-linked sialic acid and a bisecting GlcNAc linked to a core beta-mannose. | 02-05-2009 |
Tung Chan, Huntington Valley, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20100272711 | COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF CARDIOVASCULAR DISEASES - The present invention is directed to a pharmaceutical composition, and methods of use thereof, comprising at least one agent which target multiple adenosine receptors (AR) simultaneously in a stoichiometric relationship (i.e. each AR receptor is targeted to an equal extent). Aspects of the present invention relate to pharmaceutical compositions, and uses thereof, comprising at least one agent which co-activates an A | 10-28-2010 |