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Chalmers, CA

Derek Chalmers, Cardiff, CA US

Patent application numberDescriptionPublished
20110177612Human G Protein-Coupled Receptors and Modulators Thereof for the Treatment of Metabolic-Related Disorders - The present invention relates to methods of identifying whether a candidate compound is a modulator of a G protein-coupled receptor (GPCR). In preferred embodiments, the GPCR is human. In other preferred embodiments, the GPCR is coupled to Gi and lowers the level of intracellular cAMP. In other preferred embodiments, the GPCR is expressed endogenously by adipocytes. In further preferred embodiments, the GPCR inhibits intracellular lipolysis. In other further preferred embodiments, the GPCR is a nicotinic acid receptor. The present invention also relates to methods of using a modulator of said GPCR. Preferred modulator is agonist. Agonists of the invention are useful as therapeutic agents for the prevention or treatment of metabolic-related disorders, including dyslipidemia, atherosclerosis, coronary heart disease, stroke, insulin resistance, and type 2 diabetes.07-21-2011

Donald J. Chalmers, Chula Vista, CA US

Patent application numberDescriptionPublished
20080216827INTUBATION DEVICES AND METHODS OF USE THEREOF - An intubation device having a longitudinal, flexible frame with a leader guide positioned at the distal region of the frame and at least one restraint attached to the frame that is adapted to hold and guide a medical tube. The device facilitates the process of inserting a medical tube into a body cavity so as to achieve minimal patient discomfort. The intubation device described herein allows a medical professional to insert a nasogastric tube into a patient's nose, past the soft palate, and into the esophagus while significantly lessening the chances for error and alleviating the problems of tissue abrasion and improper insertion.09-11-2008

Douglas W. Chalmers, Palo Alto, CA US

Patent application numberDescriptionPublished
20090155436Fluid container with a disposable filter - Embodiments of a fluid container with a disposable filter have been presented. In some embodiments, the filter includes a housing having a top and a bottom, a first integral strainer coupled to the top, a second integral strainer coupled to the bottom, and some filtration particles stored within the housing between the first and the second integral strainers. Furthermore, some embodiments of the filter further include a flange coupled to the top, where the flange may have an outer circumference larger than a circumference of the top of the housing, and an inner circumference smaller than the circumference of the top of the housing.06-18-2009

F. Steven Chalmers, Roseville, CA US

Patent application numberDescriptionPublished
20100228785Row Column Storage - A method for accessing data is disclosed. The method comprises writing data for a multi-dimensional array to a physical storage device. The data is written to a physical storage device as two different linear strings. The first linear string contains the data from the multi-dimensional array in row format and the second linear string contains the data from the multi-dimensional array in column format.09-09-2010

James Macallen Chalmers, Danville, CA US

Patent application numberDescriptionPublished
20090183548METHOD AND APPARATUS FOR IN SITU TESTING OF GAS FLOW CONTROLLERS - Methods and apparatus utilize a rate of drop in pressure upstream of a gas flow controller (GFC) to accurately measure a rate of flow through the GFC. Measurement of the gas flow through the many gas flow controllers in production use today is enabled, without requiring any special or sophisticated pressure regulators or other special components. Various provisions ensure that none of the changes in pressure that occur during or after the measurement perturb the constant flow of gas through the GFC under test.07-23-2009
20090183549METHOD AND APPARATUS FOR IN SITU TESTING OF GAS FLOW CONTROLLERS - Methods and apparatus utilize a rate of drop in pressure upstream of a gas flow controller (GFC) to accurately measure a rate of flow through the GFC. Measurement of the gas flow through the many gas flow controllers in production use today is enabled, without requiring any special or sophisticated pressure regulators or other special components. Various provisions ensure that none of the changes in pressure that occur during or after the measurement perturb the constant flow of gas through the GFC under test.07-23-2009
20110011183METHOD AND APPARATUS FOR IN SITU TESTING OF GAS FLOW CONTROLLERS - Methods and apparatus utilize a rate of drop in pressure upstream of a gas flow controller (GFC) to accurately measure a rate of flow through the GFC. Measurement of the gas flow through the many gas flow controllers in production use today is enabled, without requiring any special or sophisticated pressure regulators or other special components. Various provisions ensure that none of the changes in pressure that occur during or after the measurement perturb the constant flow of gas through the GFC under test.01-20-2011
20110137581METHOD AND APPARATUS FOR ENHANCING IN-SITU GAS FLOW MEASUREMENT PERFORMANCE - An in-situ gas flow measurement controller measures the temperature and rate of pressure drop upstream from a flow control device (FCD). The controller samples the pressure and temperature data and applies the equivalent of a decimating filter to the data to produce filtered data at a slower sampling rate. The controller derives timestamps by counting ticks from the sampling clock of the A/D converter that is sampling the pressure at regular intervals to ensure the timestamps associated with the pressure samples are accurate and do not contain jitter that is associated with software clocks. The controller additionally normalizes the temperature reading to account for power supply fluctuations, filters out noise from the pressure and temperature readings, and excludes data during periods of instability. It calculates the gas flow rate accounting for possible non-linearities in the pressure measurements, and provides the computed gas flow measurement via one of many possible interfaces.06-09-2011
20110137582METHOD AND APPARATUS FOR ENHANCING IN-SITU GAS FLOW MEASUREMENT PERFORMANCE - An in-situ gas flow measurement controller measures the temperature and rate of pressure drop upstream from a flow control device (FCD). The controller samples the pressure and temperature data and applies the equivalent of a decimating filter to the data to produce filtered data at a slower sampling rate. The controller derives timestamps by counting ticks from the sampling clock of the A/D converter that is sampling the pressure at regular intervals to ensure the timestamps associated with the pressure samples are accurate and do not contain jitter that is associated with software clocks. The controller additionally normalizes the temperature reading to account for power supply fluctuations, filters out noise from the pressure and temperature readings, and excludes data during periods of instability. It calculates the gas flow rate accounting for possible non-linearities in the pressure measurements, and provides the computed gas flow measurement via one of many possible interfaces.06-09-2011
20110137583METHOD AND APPARATUS FOR ENHANCING IN-SITU GAS FLOW MEASUREMENT PERFORMANCE - An in-situ gas flow measurement controller measures the temperature and rate of pressure drop upstream from a flow control device (FCD). The controller samples the pressure and temperature data and applies the equivalent of a decimating filter to the data to produce filtered data at a slower sampling rate. The controller derives timestamps by counting ticks from the sampling clock of the A/D converter that is sampling the pressure at regular intervals to ensure the timestamps associated with the pressure samples are accurate and do not contain jitter that is associated with software clocks. The controller additionally normalizes the temperature reading to account for power supply fluctuations, filters out noise from the pressure and temperature readings, and excludes data during periods of instability. It calculates the gas flow rate accounting for possible non-linearities in the pressure measurements, and provides the computed gas flow measurement via one of many possible interfaces.06-09-2011

Jim Chalmers, Danville, CA US

Patent application numberDescriptionPublished
20090005894METHOD AND SYSTEM FOR ENHANCING THE YIELD IN SEMICONDUCTOR MANUFACTURING - Roughly described, a manufacturing process is enhanced by using TCAD and TCAD-derived models. A TCAD simulation model of the process is developed, which predicts, in dependence upon a plurality of process input parameters, a value for a performance parameter of a product to be manufactured using the process. Estimated, predicted or desired values for a calculated subset of the parameters (including either process input parameters or product performance parameters or both), are determined in dependence upon the process model, and further in dependence upon actual, estimated or desired values for a different subset of the parameters (again either process input parameters or product performance parameters or both). The determination is preferably made using a process compact model of the process, itself developed in dependence upon the simulation model.01-01-2009
20100121474Method and System for Enhancing the Yield In Semiconductor Manufacturing - Roughly described, a manufacturing process is enhanced by using TCAD and TCAD-derived models. A TCAD simulation model of the process is developed, which predicts, in dependence upon a plurality of process input parameters, a value for a performance parameter of a product to be manufactured using the process. Estimated, predicted or desired values for a calculated subset of the parameters (including either process input parameters or product performance parameters or both), are determined in dependence upon the process model, and further in dependence upon actual, estimated or desired values for a different subset of the parameters (again either process input parameters or product performance parameters or both). The determination is preferably made using a process compact model of the process, itself developed in dependence upon the simulation model.05-13-2010

Mary Ellen S. Chalmers, Santa Rosa, CA US

Patent application numberDescriptionPublished
20100082027Frequency specific micocurrent for treatment of dental indications - Protocols are provided for the use of frequency specific microcurrent in conjunction with dental or orthodontic procedures to treat or prevent inflammation induced complications. Specific protocols are disclosed for use in conjunction with gingival surgery and chronic periodontitis, implant/osseous periodontal surgery, general post operative trauma, pulpal trauma, pulpal inflammation, root canal post op, chronic osteonecrosis, osteonecrosis surgery post op, orthodontic pain prevention, and orthodontic mid-adjustment procedures.04-01-2010

Scott A. Chalmers, San Diego, CA US

Patent application numberDescriptionPublished
20110170097Fiber-Based Optical Probe With Decreased Sample-Positioning Sensitivity - Reflectance systems and methods are described that under-fill the collection fiber of a host spectrometer both spatially and angularly. The under-filled collection fiber produces a response of fiber-based spectrometers that is relatively insensitive to sample shape and position.07-14-2011

Steven F. Chalmers, Roseville, CA US

Patent application numberDescriptionPublished
20100250785NPIV AT STORAGE DEVICES - One embodiment is a storage device that has multiple physical ports receiving input/outputs (I/Os) from a host computer. Each of the ports presents plural virtual ports using N_Port ID Virtualization (NPIV) to prioritize the I/Os.09-30-2010