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Chakravarti, US

Aravinda Chakravarti, Lutherville, MD US

Patent application numberDescriptionPublished
20100047777METHODS FOR IDENTIFYING MUTATIONS IN CODING AND NON-CODING DNA - The present invention provides methods of identifying mutations in nucleic acid. Also provided herein are methods of identifying subjects having Hirschsprung disease risk and diagnostic markers for Hirschsprung disease.02-25-2010

Arnab Chakravarti, Dublin, OH US

Patent application numberDescriptionPublished
20100144540CORRELATION OF MOLECULAR MARKERS WITH CLINICAL OUTCOME IN GBM PATIENTS RADIATION TREATED WITH OR WITHOUT GEFITINIB - Interestingly, for prognosis, the significant biomarkers for Gefitinib-treated GBM patients (RTOG 0211) appeared to differ compared to historical, RT and non-Gefitinib-treated GBM patients. In Gefitinib-treated patients, those with higher levels of nuclear pAKT driven by PTEN loss, higher levels of nuclear pMAPK, and lower levels of nuclear pmTOR had significantly worse clinical outcomes. In contrast, in non-Gefitinib-treated patients, patients with PTEN-deficiency, and higher levels of EGFRvIII, total EGFR, IGFR1, NFkB and lower levels of nuclear Survivin appeared to have adverse clinical outcomes, highlighting the treatment-dependency of these biomarkers.06-10-2010

Bhaven Chakravarti, Bellaire, TX US

Patent application numberDescriptionPublished
20110017339METHOD FOR ROLLED SEAMLESS CLAD PIPES - A method of forming clad piping or tubing includes the steps of forming an assembly of a support billet having a cladding surface and a cladding material billet, sized to cooperate with the cladding surface of the support billet, with an interface gap defined between the cladding material billet and the cladding surface of the support billet, sealing the interface gap, evacuating the interface gap and metallurgically bonding the cladding material billet to the support billet by a Hot Iso-static Pressing or weld overlay process to form a composite billet, and hot-rolling through a rotary mill the composite billet to form the clad piping or tubing.01-27-2011
20110017807METHOD FOR ROLLED SEAMLESS CLAD PIPES - A method of forming clad piping or tubing includes the steps of forming an assembly of a support billet having a cladding surface and a cladding material billet, sized to cooperate with the cladding surface of the support billet, with an interface gap defined between the cladding material billet and the cladding surface of the support billet, sealing the interface gap, evacuating the interface gap and metallurgically bonding the cladding material billet to the support billet by a Hot Iso-static Pressing process to form a composite billet; and hot-rolling through a rotary mill the composite billet to form the clad piping or tubing.01-27-2011

Deb Narayan Chakravarti, Claremont, CA US

Patent application numberDescriptionPublished
20090075839Novel streptococcus pneumoniae open reading frames encoding polypeptide antigents and uses thereof - The present invention relates to newly identified open reading frames comprised within the genomic nucleotide sequence of 03-19-2009
20100221288NOVEL STREPTOCOCCUS PNEUMONIAE OPEN READING FRAMES ENCODING POLYPEPTIDE ANTIGENS AND USES THEREOF - The present invention relates to newly identified open reading frames comprised within the genomic nucleotide sequence of 09-02-2010

Jamuna Chakravarti, Evansville, IN US

Patent application numberDescriptionPublished
20100003523Coated Film for Insert Mold Decoration, Methods for Using the Same, and Articles Made Thereby - A coated thermoplastic film can be subjected to printing to obtain a decorative film, preformed (for example, thermoformed), and then inserted into a mold that has the configuration of the preformed decorative film. A base polymeric structure comprising a polymer such as a polycarbonate or blend thereof can be injection molded to the exposed surface of the preformed decorative film. The molded structure has various applications such as cell phones or other electronic devices, automotive vehicles, appliances, display panels, lenses, etc. A process for making the molded article is also described. The coating for the coated thermoplastic film can be made from a UV-curable composition and can provide superior embossing and thermoformability, hardness, and adhesion, while providing enhanced chemical, scratch and abrasion resistance.01-07-2010
20110183120Coated Film for Insert Mold Decoration, Methods for Using the Same, and Articles Made Thereby - A coated thermoplastic film can be subjected to printing to obtain a decorative film, preformed (for example, thermoformed), and then inserted into a mold that has the configuration of the preformed decorative film A base polymeric structure comprising a polymer such as a polycarbonate or blend thereof can be injection molded to the exposed surface of the preformed decorative film The molded structure has various applications such as cell phones or other electronic devices, automotive vehicles, appliances, display panels, lenses, etc. A process for making the molded article is also described. The coating for the coated thermoplastic film can be made from a UV-curable composition and can provide superior embossing and thermoformability, hardness, and adhesion, while providing enhanced chemical, scratch and abrasion resistance.07-28-2011

Patent applications by Jamuna Chakravarti, Evansville, IN US

Joydeep Chakravarti, Cupertino, CA US

Patent application numberDescriptionPublished
20090252030REDUCING TRAFFIC LOSS IN AN EAPS SYSTEM - A ring network with an automatic protection switching domain includes a control VLAN and at least one data VLAN. A master node in the ring is connected to at least one transit node. Each node in the ring network is linked to an adjacent node by a primary port or a secondary port. The master node receives notification of a fault via the control VLAN, the fault indicating a failed link between adjacent nodes. In response, the master node unblocks its secondary port to traffic on the data VLAN(s). The forwarding database entries on the master node and on the transit node(s) are flushed. Data traffic is flooded to the ring network until forwarding database entries on the master node and on the transit node(s) have been reestablished.10-08-2009

Shukti Chakravarti, Lutherville, MD US

Patent application numberDescriptionPublished
20090258848BIOMARKERS FOR INFLAMMATORY BOWEL DISEASE - The present invention relates to methods of determining inflammatory bowel disease status in a subject. The invention further relates to kits for determining inflammatory bowel disease status in a subject. The invention further related to methods of identifying biomarker for determining inflammatory bowel disease status in a subject.10-15-2009
20100098699Methods of using LRR superfamily genes and proteins - The instant application provides methods and compositions for the treatment of inflammation, for modulating the activity or expression of proinflammatory cytokines, for increasing the rate of wound healing, for treating infection, and for treating septic shock. The invention provides lumican, or modulators thereof, as a therapeutic composition for the treatment of these disorders.04-22-2010
20110082188GENE EXPRESSION PROFILING OF INFLAMMATORY BOWEL DISEASE - The present invention relates to methods for identifying and/or classifying patients with inflammatory bowel diseases (IBD), particularly patients with Crohn's disease or ulcerative colitis. Gene expression profiling shows broad and fundamental differences in the pathogenic mechanism of UC and CD. The subject method is based on the findings that certain genes are differentially expressed in intestinal tissue of IBD patients compared with related normal cells, such as normal colon cells. That change can be used to identify or classify IBD cells by the upregulation and/or downregulation of expression of particular genes, alterations in protein levels or modification, or changes at the genomic level (such as mutation, methylation, etc), e.g., an event which is implicated in the pathology of inflammatory bowel diseases.04-07-2011

Patent applications by Shukti Chakravarti, Lutherville, MD US

Soham Chakravarti, Middletown, CT US

Patent application numberDescriptionPublished
20090210256System For Real-Time Online Health Care Insurance Underwriting - A system for real-time health care insurance underwriting is described comprising a quotation module, a verification module, and an underwriting module. The quotation module receives user input relating to a user's health status via an online user interface. The verification module verifies the user input against information stored in a database to form a list of inconsistencies and present the user via the online user interface with a request to validate at least some information within the user input. The underwriting module automatically creates a debit score based on one or more of at least a portion of the user input and the validated information and generates an underwriting decision based at least in part on the debit score. The quotation module presents one or more offers to sell insurance to the user via the online user interface, the one or more offers based on the underwriting decision.08-20-2009

Suman K. Chakravarti, Beachwood, OH US

Patent application numberDescriptionPublished
20110257270DRUG FOR TREATMENT OF COLON CANCER - A first aspect of the invention provides a method for treating, preventing or ameliorating a hyperproliferative disease and/or disorder in a mammal comprising administering to the mammal a therapeutically effective amount of one or more compounds selected from the group consisting of compounds of Formula (1), (2), or a pharmaceutically acceptable salt or metabolite thereof.10-20-2011