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Chae, Daejeon

Byung Gyu Chae, Daejeon KR

Patent application numberDescriptionPublished
20100157542POWER DEVICE PACKAGE HAVING ENHANCED HEAT DISSIPATION - A power device package controls heat generation of a power device using a semi-permanent metal-insulator transition (MIT) device instead of a fuse, and emits heat generated by the power device through a small-sized heat sink provided only in one region on the power device, thereby ensuring excellent dissipation of heat. Therefore, the power device package can be usefully applied to any electric/electronic circuit that uses a power device.06-24-2010

Cheol-Joo Chae, Daejeon KR

Patent application numberDescriptionPublished
20110244484METHOD OF DIAGNOSING ALZHEIMER'S DISEASE USING GIANT MAGNETORESISTANCE SENSOR AND MAGNETIC BEAD-POLYPROTEIN COMPLEX FOR DIAGNOSING ALZHEIMER'S DISEASE - Provided are a method of diagnosing Alzheimer's disease using a giant magnetoresistance sensor and a magnetic bead-polyprotein complex for diagnosing Alzheimer's disease. The method of diagnosing Alzheimer's disease using the giant magnetoresistance sensor may be applied to diagnose Alzheimer's disease more easily and simply using the giant magnetoresistance sensor than using conventional fluorescent materials or genetic analyses, and the magnetic bead-polyprotein complex may be mass-produced as a diagnostic biosensor for Alzheimer's disease, and thus to be useful to monitor and treat Alzheimer's disease.10-06-2011
20110262934METHOD FOR EARLY DIAGNOSIS OF ALZHEIMER'S DISEASE USING PHOTOTRANSISTOR - Disclosed is a method for the early diagnosis of Alzheimer's disease. In the method, cells in which a biomarker characteristic of Alzheimer's disease, preferably beta-amyloid, is labeled with magnetic beads are selectively located in the channel region of a phototransistor, and a difference in photocurrent between normal cells and the cells comprising the protein biomarker labeled with magnetic beads is sensed to diagnose Alzheimer's disease at an early stage.10-27-2011

Eun Hee Chae, Daejeon KR

Patent application numberDescriptionPublished
20100160331NOVEL CARBAMOYLOXY ARYLALKAN ARYLPIPERAZINE COMPOUND, PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUND AND METHOD FOR TREATING PAIN, ANXIETY AND DEPRESSION BY ADMINISTERING THE COMPOUND - There is provided a novel carbamoyloxy arylalkanoyl arylpiperazine derivative compound having abundant racemic or enantiomeric characteristics, represented by the Formula 1, and pharmaceutically available salts or hydrates thereof. Also, there are provided a pharmaceutical composition for treating pain, anxiety or depression including an effective amount of the compound, and a method for treating pain, anxiety or depression in mammals by administering an effective amount of the compound to the mammals in need of treatment thereof.06-24-2010
20110195963NOVEL CARBAMOYLOXY ARYLALKANOYL ARYLPIPERAZINE COMPOUND, PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUND AND METHOD FOR TREATING PAIN, ANXIETY AND DEPRESSION BY ADMINISTERING THE COMPOUND - There is provided a novel carbamoyloxy arylalkanoyl arylpiperazine derivative compound having abundant racemic or enantiomeric characteristics, represented by the Formula 1, and pharmaceutically available salts or hydrates thereof. Also, there are provided a pharmaceutical composition for treating pain, anxiety or depression including an effective amount of the compound, and a method for treating pain, anxiety or depression in mammals by administering an effective amount of the compound to the mammals in need of treatment thereof.08-11-2011

Gee Ju Chae, Daejeon KR

Patent application numberDescriptionPublished
20090073000METHOD AND APPARATUS FOR ALERTING ABOUT DRIVING STATE OF VEHICLE - A method and apparatus for alerting a driving state of a vehicle is provided. The method of alerting about a driving state of a vehicle includes: identifying an adjacent vehicle from a photographed image and extracting identification information about the adjacent vehicle; determining whether the adjacent vehicle approaches based on the identification information; and alerting a driver of the vehicle about a hazard due to the adjacent vehicle approaching, when the adjacent vehicle approaches.03-19-2009

Jeong Sook Chae, Daejeon KR

Patent application numberDescriptionPublished
20110309967APPARATUS AND THE METHOD FOR DISTINGUISHING GROUND AND OBSTACLES FOR AUTONOMOUS MOBILE VEHICLE - Disclosed is apparatus for distinguishing between ground and an obstacle for autonomous mobile vehicle, comprising an upper 2D laser radar 12-22-2011

Je-Wook Chae, Daejeon KR

Patent application numberDescriptionPublished
20110107641Link Type Percussion Lock - Disclosed is a percussion lock installed on a firearm, and more particularly, to a percussion lock wherein the hammer is operated through a link member so that operation of the firearm is possible in a small area, making it possible to design a firearm flexibly and reducing the volume and weight of the firearm. According to the present invention, the percussion lock installed on a firearm to fire a bullet by hitting a firing pin comprises a housing mounted in fixed state to a firearm, a hammer installed on the upper part of the housing for hitting a firing pin, a link member linking the hammer and the housing so that the hammer moves on a curve maintaining horizontal state, and an elastic member supporting the link member with elastic force.05-12-2011

Ji-Hwa Chae, Daejeon KR

Patent application numberDescriptionPublished
20100047308Production methods of virus inactivated and cell-free body implant - A method is provided for producing a virus-inactivated, acellular implant for the human body, featuring the use of TNBP in combination with a detergent selected from among deoxycholate, SDS, Tween 80, Triton X-100, sodium cholate and combinations thereof for removing cells and viruses simultaneously. Also disclosed are an acellular human body implant produced by the method and a wound healing agent comprising the acellular human body implant.02-25-2010
20100129421COMPOSITION FOR PROMOTING BONE REGENERATION AND RESTORATION - A bone grafting material composite is provided. The bone grafting material composite includes a demineralized bone matrix (DBM) and a carboxymethyl cellulose (CMC)/glycerol gel carrier. Due to the CMC/glycerol gel carrier, the implantation ability thereof is better than that of the DBM. Therefore, the bone grafting material composite can be easily used, so that a curative effect can be greatly improved. In addition, since the CMC/glycerol gel is used as a carrier, the composite with a mobility maintained is washed out by water after surgery, so that the composite can be fixed on a damaged portion of a bone.05-27-2010

Jong Ho Chae, Daejeon KR

Patent application numberDescriptionPublished
20090147613DEVICE FOR PROTECTING SRAM DATA - A device for protecting data stored in a static random access memory (SRAM) is provided. More particularly, a device for protecting SRAM data including an SRAM data erasing circuit, which erases memory stored in an SRAM at once when illegal separation from a system is detected. The device for protecting SRAM data includes: a power switching circuit for outputting electrical power supplied from an external power supply or a back-up battery power supply depending on whether the external power supply is supplying the electrical power or not; and an SRAM data erasing circuit for supplying the electrical power output from the power switching circuit to a power input terminal of a SRAM or grounding the power input terminal of the SRAM, in response to a connecter connection signal. The device can prevent illegal leakage of SRAM data by erasing the data stored in the SRAM when the SRAM is illegally separated from a system according to the switch setting of the SRAM data erasing circuit.06-11-2009

Jong Hoon Chae, Daejeon KR

Patent application numberDescriptionPublished
20090200382Combi-Card and Method for Making the Same - The present invention relates to a combi-card which can be used in a contact-type or noncontact-type fashion and a method for manufacturing the same. More particularly, this invention relates to a combi-card and a method for making the same, in which an inlay layer on which an antenna terminal made of a coil or conductive fiber is formed and a COB (chip on board) on which ACF (anisotropic conductor film) is applied, are pre-treated by a heating head and the like, the COB is attached to an antenna coil insertion layer, and an upper printing sheet with a protection film, and a lower printing sheet with a protection film, which are cut out to be suitable for the COB shape, are stacked to construct a combi-card.08-13-2009
20100320270COMBI CARD AND COMMUNICATION SYSTEM USING THEREOF - Provided is a combi-card, i.e. a combination type IC card, which can be used in either contact and non-contact manner, and a communication system using the same, and the combi-card is provided with a transponder chip module formed with a RF antenna and attached in a recess region of a card body and is characterized by the use of the RF antenna of the transponder chip alone as a transmitting and receiving antenna.12-23-2010

Jong Hyun Chae, Daejeon KR

Patent application numberDescriptionPublished
20110086259WATER-RESISTANT POUCH TYPE SECONDARY CELL - The present invention relates to a pouch type secondary cell with high water-resistance. The pouch type secondary cell comprises a positive electrode, a separation layer, and a negative electrode. Here, the sealing unit of the secondary cell includes steps so that the sealing unit has an outer side thinner than an inner side in thickness. The present invention is advantageous in that the manufacture process can be simplified, the water-resistance and sealing property of sealing portions can be further improved, and the manufacture costs can be reduced.04-14-2011

Patent applications by Jong Hyun Chae, Daejeon KR

Jong-Jyun Chae, Daejeon KR

Patent application numberDescriptionPublished
20100048958METHOD FOR PURIFYING TEREPHTHALALDEHYDE - The present invention relates to a method for preparing high-purity terephthalaldehyde which comprises re-crystallizing terephthalaldehyde crystals containing impurities, using an anti-solvent. Specifically, the present invention relates to a method for preparing terephthalaldehyde which comprises dissolving low-purity terephthalaldehyde prepared by a conventional method in dimethylsulfoxide and then re-crystallizing the solution, using water as an anti-solvent. The present invention is not only environment-friendly because it uses water only as an anti-solvent, but also economical because it may simply prepare high-purity terephthalaldehyde in a short time.02-25-2010

Sang Eun Chae, Daejeon KR

Patent application numberDescriptionPublished
20100063286PIPERAZINYL-PROPYL-PYRAZOLE DERIVATIVES AS DOPAMINE D4 RECEPTOR ANTAGONISTS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME - The present invention relates to a novel piperazinyl-propyl-pyrazole derivative, a method of its preparation and a pharmaceutically acceptable composition comprising the same. The novel piperazinyl-propyl-pyrazole derivative of the present invention has superior selective affinity for dopamine D4 receptor, can effectively inhibit psychotic behavior (cage climbing) induced by apomorphine, and has relatively low adverse effects in mouse rotarod test. Therefore, it can be developed as a therapeutic agent for the treatment and prevention of central nervous system (CNS) disorders, in particular, schizophrenia, attention deficit hyperactivity disorder, depression, stress diseases, panic disorder, phobia, obsessive-compulsive disorder, posttraumatic stress disorder, cognitive disorder, Alzheimer's disease, Parkinson's disease, anxiety, paraphrenia, mania, seizure disorder, personality disorder, migraine, drug addiction, alcohol addiction, obesity, eating disorder, and sleeping disorder.03-11-2010
20100184781FXA INHIBITORS WITH CYCLIC AMIDINES AS P4 SUBUNIT, PROCESSES FOR THEIR PREPARATIONS, AND PHARMACEUTICAL COMPOSITIONS AND DERIVATIVES THEREOF - The present invention relates to novel oxazolidinone derivatives with cyclic amidines, and prodrugs, hydrates, solvates, isomers and pharmaceutically acceptable salts thereof, and processes for preparing the same, and pharmaceutical compositions comprising the same. The oxazolidinone derivatives with cyclic amidines, and prodrugs, hydrates, solvates, isomers and pharmaceutically acceptable salts thereof can be usefully employed as an anticoagulant for treating thromboembolism and tumors via inhibition of coagulation factor Xa.07-22-2010
20110112083FXA INHIBITORS WITH CYCLIC AMIDOXIME OR CYCLIC AMIDRAZONE AS P4 SUBUNIT, PROCESSES FOR THEIR PREPARATIONS, AND PHARMACEUTICAL COMPOSITIONS AND DERIVATIVES THEREOF - The present invention relates to novel oxazolidinone derivatives with cyclic amidoxime or cyclic amidrazone group, pharmaceutically acceptable salts thereof, methods for preparing the same and pharmaceutical compositions comprising the same. The oxazolidinone derivatives with cyclic amidoxime or cyclic amidrazone group or the pharmaceutically acceptable salts thereof can be effectively used for the treatment of thromboembolism and tumor as an anticoagulant based on the inhibition of factor Xa.05-12-2011
20110178293Novel Oxazolidinone Derivatives with Cyclic Amidoxime or Cyclic Amidrazone and Pharmaceutical Compositions Thereof - Disclosed is a novel oxazolidinone derivative, particularly a novel oxazolidinone compound with a cyclic amidoxime or cyclic amidrazone group. Also disclosed is a pharmaceutical antibiotic composition including a novel oxazolidinone derivative, a prodrug thereof, a hydrate thereof, a solvate thereof, an isomer thereof or a pharmaceutically acceptable salt thereof as an effective ingredient. Because the novel oxazolidinone derivative, a prodrug thereof, a hydrate thereof, a solvate thereof, an isomer thereof or a pharmaceutically acceptable salt thereof exhibits a wide antibacterial spectrum against resistant bacteria, a low toxicity, and a strong antibacterial activity against Gram-positive and Gram-negative bacteria, it can be usefully used as an antibiotic.07-21-2011

Seong-Hwan Chae, Daejeon KR

Patent application numberDescriptionPublished
20100177393Reflective structure, display apparatus including the reflective structure, and method of manufacturing the reflective structure and display apparatus - Example embodiments relate to a reflective structure, a display apparatus including the reflective structure, and a method of manufacturing the reflective structure and the display apparatus. A reflective structure according to example embodiments may include a plurality of nanoparticles of non-uniform size, which are arranged on a substrate, or an uneven element having a surface contour that resembles a plurality of nanoparticles; and a reflective layer covering the plurality of nanoparticles or the uneven element. The reflective layer may have a random/variable height.07-15-2010

Seung Hun Chae, Daejeon KR

Patent application numberDescriptionPublished
20100134910OPTICAL FILM AND METHOD OF MANUFACTURING THE SAME - There is provided an optical film. The optical film includes at least one retardation film and at least one isotropic layer made of an isotropic material, wherein the difference in average refractive index between the retardation film and the isotropic layer is at least 0.1 or more. Also, the method of adjusting wavelength dispersion characteristics of an optical film includes: stacking an isotropic layer onto a retardation film. The present invention provides a method for preparing optical films having a variety of wavelength dispersion characteristics by the simple method of coating the retardation film with the isotropic layer.06-03-2010
201102054593D GLASSES FOR STEREOSCOPIC DISPLAY DEVICE AND STEREOSCOPIC DISPLAY DEVICE INCLUDING THE SAME - There are provided 3D glasses for use in a stereoscopic display device including a display panel for emitting right-eye image light and left-eye image light and an optical filter including a first area for adjusting a polarized state of the right-eye image light and a second area for adjusting a polarized state of the left-eye image light, comprising a right-eye area allowing right-eye image light to pass therethrough and a left-eye area allowing left-eye image light to pass therethrough; and compensation films disposed at the right-eye area and the left-eye area to compensate for a phase difference deviation between the first and second areas of the optical filter, wherein a phase difference value of the compensation film provided at the right-eye area and that of the compensation film provided at the left-eye area are different.08-25-2011

Patent applications by Seung Hun Chae, Daejeon KR

Su Chang Chae, Daejeon KR

Patent application numberDescriptionPublished
20100019888APPARATUS AND METHOD FOR PROVIDING URL, MOBILE STATION, AND METHOD FOR ACCESSING INTERNET BY USING THE PROVIDED URL - The present invention relates to a URL providing apparatus and a method thereof, and a mobile station that accesses the Internet by using the provided URL, and an Internet access method thereof. The mobile station attaches an RF-ID tag that stores an RF-ID tag value corresponding to identification information of the mobile station thereto, and thus when a user brings the mobile station into an interrogation range of an RF-ID reader included in the URL providing apparatus, the URL providing apparatus receives the corresponding RF-ID tag value from the RF-ID reader. When the URL providing apparatus acquires an IP address of the mobile station by using the received RF-ID tag value and provides a URL to the mobile station by using the acquired IP address, the mobile station automatically accesses the Internet by using the URL. Such an Internet access method can minimize additional cost of the mobile station and simplify an Internet access process to a specific URL.01-28-2010
20100265828COMMUNICATION AND METHOD - A communication method according to the present invention includes receiving MAP in formation, acquiring an initial scheduled frame number and a current frame number from the MAP information, calculating the difference between the initial scheduled frame number and the current frame number, comparing the difference between the initial scheduled frame number and the current frame number with a reference value and setting a scheduled frame number, and performing transmission or reception in the scheduled frame. Therefore, even though a MAP loss occurs, the mobile station can receive only downlink data effective in downlink, thereby reducing power consumption for unnecessary reception, and can exactly perform transmission in a frame in which it should transmit in uplink.10-21-2010
20100290401METHOD OF TRANSMITTING SIGNAL - A method of transmitting a signal according to the present invention includes: receiving a signal that is encoded with a predetermined code rate and that is modulated by a first modulation method from a base station; creating a signal that is obtained by demodulating the signal that is modulated by the first modulation method using a method corresponding to the first modulation method; creating a signal that is obtained by modulating the demodulated signal using a second modulation method while maintaining the predetermined code rate; and transmitting the signal that is modulated by the second modulation to a mobile station.11-18-2010

Sungseok Chae, Daejeon KR

Patent application numberDescriptionPublished
20100113720METHOD FOR PREPARING ELASTOMERIC COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS - Provided is a process for preparing copolymers of ethylene with α-olefin. More specifically, provided are transition metal compound being useful as catalyst for preparing those copolymers, a catalyst composition comprising the same, and a process for preparing elastic copolymers of ethylene with α-olefin, having the density of not more than 0.910, which can be adopted to a wide variety of applications including film, electric wires, and hot-melt adhesives. The catalyst composition is a catalytic system which comprises transition metal catalyst comprising a cyclopentadiene derivative and at least one anionic ligand(s) of aryloxy group with an aryl derivative at ortho-position, and boron or aluminum compound as an activator. Provided is a process for copolymerizing ethylene with α-olefin to produce copolymer having narrow molecular weight distribution and uniform density distribution with the density of not more than 0.910, with high activity and excellent reactivity on higher α-olefin.05-06-2010
20100113729ETHYLENE COPOLYMER WITH IMPROVED IMPACT RESISTANCE - Provided are ethylene copolymers with excellent impact resistance. More specifically, provided are ethylene copolymers satisfying certain correlation between the falling dart impact strength (F) or high rate impact resistant breakage energy (E) and Vicat softening point. The ethylene copolymers with improved impact properties are applicable to film, injection, compound, sheet, roto, pipe or blow molding.05-06-2010
20100120981ETHYLENE COPOLYMER AND A METHOD OF PREPARING THE SAME - Provided are ethylene copolymers and a process for preparing the same. More specifically, provided are ethylene copolymers exhibiting excellent processibility and physical properties due to its multimodal molecular weight distribution index, through a multi-stage process by using reactors connected in series or in parallel in the presence of catalyst composition containing transition metal catalyst, and a process for preparing the same.05-13-2010
20110282011METHOD FOR PREPARING ELASTOMERIC COPOLYMERS OF ETHYLENE AND a-OLEFINS - Provided is a process for preparing copolymers of ethylene with α-olefin. More specifically, provided are transition metal compound being useful as catalyst for preparing those copolymers, a catalyst composition comprising the same, and a process for preparing elastic copolymers of ethylene with α-olefin, having the density of not more than 0.910, which can be adopted to a wide variety of applications including film, electric wires, and hot-melt adhesives. The catalyst composition is a catalytic system which comprises transition metal catalyst comprising a cyclopentadiene derivative and at least one anionic ligand(s) of aryloxy group with an aryl derivative at ortho-position, and boron or aluminum compound as an activator. Provided is a process for copolymerizing ethylene with α-olefin to produce copolymer having narrow molecular weight distribution and uniform density distribution with the density of not more than 0.910, with high activity and excellent reactivity on higher α-olefin.11-17-2011

Sung Seok Chae, Daejeon KR

Patent application numberDescriptionPublished
20100137669ETHYLENE TETRAMERIZATION CATALYST SYSTEMS AND METHOD FOR PREPARING 1-OCTENE USING THE SAME - Disclosed herein is a method of preparing 1-octene at high activity and high selectivity while stably maintaining reaction activity by tetramerizing ethylene using a chromium-based catalyst system comprising a transition metal or a transition metal precursor, a cocatalyst, and a P—C—C—P backbone structure ligand represented by (R06-03-2010
20100145124ETHEYENE OLIGOMERIZA CATALYST SYSTEMS HAVING ENEHANCED SELECTIVITY - Disclosed herein is a catalyst system for selective oligomerization of ethylene, which comprises a P—C—C—P frame-work ligand, which is (R06-10-2010
20100234545ETHYLENE COPOLYMER HAVING MULTIPLE PITCH MOLECULAR WEIGHT DISTRIBUTION AND THE METHOD OF PREPARING THE SAME - Disclosed are an ethylene polymerization process, a catalyst for use in the process, a production method employing the catalyst, and a product produced thereby. More specifically, disclosed is a process of producing an ethylene copolymer from ethylene and an alpha-olefin comonomer, in which the produced ethylene copolymer has a multimodal molecular weight distribution and excellent processability and physical properties, and thus can increase the value and productivity of products, including pipes and films. Particularly, the produced ethylene copolymer has a trimodal or higher molecular weight distribution or density distribution, and thus, when it is a linear low-density copolymer, it has an excellent effect of improving the impact strength of films, and when it is a medium-density ethylene copolymer, it can be produced into pipes, which have slow crack growth rate and can be used even at high temperature.09-16-2010

Won Seok Chae, Daejeon KR

Patent application numberDescriptionPublished
20090153577METHOD AND SYSTEM FOR TEXTURING OF 3D MODEL IN 2D ENVIRONMENT - A method for texturing of 3D model in 2D environment includes (a) generating a texture map set for 3D model data; (b) UV unwrapping the 3D model data on each of projected planes to obtain a UV map set for each projected plane; (c) performing a 2D image authoring on the UV map set for each projected plane to produce an edited image; and (d) mapping the texture map set and the UV map set by reflecting the edited image to the texture map set and the UV map sets that are generated previously until a desired texture map set is completed.06-18-2009
20100245610METHOD AND APPARATUS FOR PROCESSING DIGITAL IMAGE - A digital image photographing method includes: recognizing a subject by analyzing an image photographed by a digital image photographing apparatus; separating the recognized subject from a background in the image; and displaying a recommending lead line of a rule of thirds on a display of the digital image photographing apparatus to help position the recognized subject on an intersection point of transversal and vertical trisectional lines. Further, the digital image photographing method includes recommending a composition, a pose and a motion which are matched to the recognized subject and the background with reference to pre-recorded information about the composition, the pose and the motion.09-30-2010

Yeong Nam Chae, Daejeon KR

Patent application numberDescriptionPublished
20090196506SUBWINDOW SETTING METHOD FOR FACE DETECTOR - Disclosed herein is a subwindow setting method for a face detector for detecting whether one or more facial images exist in each of subwindows having a set size while sequentially setting the subwindows in the width direction of an input image. A scan interval between two neighboring subwindows under consideration in the width direction is determined based on the facial color density of a first subwindow of the two neighboring subwindows. Further, a scan interval between the first and second rows in a height direction of the input image is determined based on the facial color density of the subwindows included in the first row.08-06-2009

Yeon-Jin Chae, Daejeon KR

Patent application numberDescriptionPublished
20090269414PROCESS OF PREPARING MICROSPHERES FOR SUSTAINED RELEASE HAVING IMPROVED DISPERSIBILITY AND SYRINGEABILITY - Disclosed is a process of preparing sustained release microspheres, containing a biodegradable polymer as a carrier and a drug, using spray drying. The process comprises preparing a solution, suspension or emulsion containing a biodegradable polymer, a drug and a solvent; spray drying the solution, suspension or emulsion; and suspending spray-dried microspheres in an aqueous solution containing polyvinyl alcohol to remove the residual solvent and increase the hydrophilicity of the microsphere surface. The process enables the preparation of microspheres having high drug encapsulation efficiency, almost not having a toxicity problem due to the residual solvent, and having good syringeability. The microspheres prepared according to the present invention release an effective concentration of a drug in a sustained manner for a predetermined period when administered to the body, and are thus useful in the treatment of diseases.10-29-2009
20100136126COMPOSITION AND MICROSPHERE FOR CONTROLLED-RELEASE OF EXENDIN, AND METHOD OF PREPARING THE SAME - A controlled-release composition and controlled-release microspheres containing an exendin as an active ingredient, and a method of preparing the same are provided. More specifically, a controlled-release composition containing an exendin as an active ingredient, a biodegradable polymer with a specific viscosity, and coating materials, having high bioavailability and showing sustained release of the active ingredient in an effective concentration for a certain period without an excessive initial burst of the active ingredient; controlled-release microspheres containing a core including an exendin as an active ingredient and a biodegradable polymer, and a coating layer coating the core; and a method of preparing controlled-release microspheres including the steps of mixing an exendin, a biodegradable polymer, and a solvent, removing the solvent from the mixture to prepare hardened microspheres, and coating the hardened microspheres to form a coating layer on the surface of each microsphere, are provided.06-03-2010

Patent applications by Yeon-Jin Chae, Daejeon KR