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Cerne

Gerd Cerne, Meersburg DE

Patent application numberDescriptionPublished
20100116928AIRCRAFT - The invention provides an aircraft, comprising a fuselage (05-13-2010

Manica Cerne, Lg SL

Patent application numberDescriptionPublished
20100183714GASTRORESISTANT PHARMACEUTICAL DOSAGE FORM COMPRISING N-(2-(2- PHTHALIMIDOETHOXY)-ACETYL)-L-ALANYL-D-GLUTAMIC ACID (LK-423) - The present invention relates to the pharmaceutical dosage forms which enable a controlled and/or a targeted delivery of an active substance to the selected regions of gastrointestinal tract of humans or animals. The pharmaceutical dosage forms preferably comprises the active substance N-(2(2-phthalimidoethoxy)-acetyl)-L-alanyl-D-glutamic acid (designated as LK 423). Methods of treatment of chronic inflammatory diseases of gastrointestinal tract of humans and/or animals by using the pharmaceutical dosage forms of the invention are disclosed.07-22-2010

Manica Cerne, Ig SI

Patent application numberDescriptionPublished
20080306047Use of Aza-Phenylalanine Compounds For Treating Cardiac Arrhythmia - The present invention relates to the use of certain aza-phenylalanine compounds of formula (I) wherein R12-11-2008

Rok Cerne, Lawrenceville, NJ US

Patent application numberDescriptionPublished
20080249189HETEROCYCLIC COMPOUNDS AS SWEETENER ENHANCERS - The present invention is directed to the use of a compound of Formula I10-09-2008
20080306030Use of a TRPM5 Inhibitor to Regulate Insulin and GLP-1 Release - The present invention is directed to methods of enhancing insulin release, GLP-1 release, and insulin sensitivity, methods of increasing insulin gene expression, methods of decreasing gastric secretion and emptying and glucagons secretion, and methods of inhibiting food intake, and methods of treating diabetes mellitus, insulin resistance syndrome, hyperglycemia, and obesity comprising administering to a subject an effective amount of a TRPM5 inhibitor.12-11-2008
20090136975Non-desensitizing mutant of the transient receptor potential TRPM5 ion channel - There exists a need in the art for high throughput screening assays that can identify compounds that specifically modulate the activity of fast-acting ion channels, such as TRPM5. Current methods, especially electrophysiological, suffer from a lack of sensitivity, rapid signal loss, low throughput, and are labor intensive. The claimed methods and compositions provide electrophysiology methods that allow prolonged sample testing and fluorescent assays with an optical readout that gives rapid readout of the results, has a high signal to noise background ratio, are easy to use, can be modified for automation and miniaturization, and provide verification that a compound specifically modulates TRPM5.05-28-2009
20090175848Modulation of the Cooperativity Between the Ion Channels TRPM5 and TRPA1 - The present invention is related to modulating TRPA1 ion channel activity by targeting the ion channel TRPM5. The cooperativity between the ion channels can be used to modulate pain, mechanosensation and taste responses triggered through TRPA1 by modulating the activity of TRPM507-09-2009
20100197813Heterocyclic Compounds as Sweetener Enhancers - The present invention is directed to the use of a compound of Formula I08-05-2010

Patent applications by Rok Cerne, Lawrenceville, NJ US

Virna Lucia Cerne, Duino-Aurisina (ts) IT

Patent application numberDescriptionPublished
20120027890METHOD FOR THE PRODUCTION OF MAIZE PROTEINS AND USE OF SAID PROTEINS FOR THE PRODUCTION OF GLUTEN-FREE BAKERY PRODUCTS AND PASTA - A method for the production of maize proteins comprises a step of extracting protein fractions comprising zeins and rich in glutelins from white maize and/or its sub-derivatives, such as for example flour, CGM (Corn Gluten Meal) or other, using an aqueous solution of alcohol in the absence of a reducing and purification agent. The present invention also concerns the formulation of recipes for the preparation of bakery gluten-free products and pasta with said proteins extracted02-02-2012