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Centeno, US
Christopher Centeno, Boulder, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20080255429 | SIMULATED SECONDARY GAIN MODEL WITH CONTINUOUS FEEDBACK TO DIAGNOSTIC TESTING PARAMETERS AND INTERPRETATION IN A MEDICAL LEGAL SETTING - The invention generally relates to compositions and methods for the use of a simulated secondary gain model for use in medical legal setting where there is dispute about the validity of a medical patient's injuries. This model is used to ascertain the false positive rate of a given diagnostic test or suite of same and is then used to reevaluate the test on an ongoing basis after changes have been made to reduce the false positive rate. | 10-16-2008 |
Christopher J. Centeno, Broomfield, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20110052533 | Compositions and Methods for Cartilage Repair - Autologous compositions and methods are provided for cartilage repair in patients in need thereof. Some aspects include combinations of platelet-based materials with chondrogenesis inducing agents in the presence or absence of cell-based therapies. | 03-03-2011 |
| 20110054929 | Stem Cell Marketplace - Computerized methods and systems for a stem cell marketplace are disclosed herein. Aspects of the stem cell marketplace include a registry that includes information and data necessary for a user to optimize a particular stem cell need. Aspects provide uniformity and certainty on how to proceed in personalizing a particular stem cell need, including autologous stem cell needs. | 03-03-2011 |
Christopher J. Centeno, Westminster, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20090010896 | METHODS AND COMPOSITIONS FOR OPTIMIZED EXPANSION AND IMPLANTATION OF MESENCHYMAL STEM CELLS - Compositions and methods are provided for the optimized expansion and implantation of mesenchymal stem cells into a patient in need thereof. Autologous mesenchymal stem cells (MSCs) to a patient in need of MSCs are harvested, expanded within novel growth parameters under the influence of autologous growth factors located on the patient's platelets. | 01-08-2009 |
| 20090208464 | MESENCHYMAL STEM CELL ISOLATION AND TRANSPLANTATION METHOD AND SYSTEM TO BE USED IN A CLINICAL SETTING - A system and method for the percutaneous, autologous transplantation of mesenchymal stem cells and progenitor helper cells (PHC) from bone marrow to degenerated intervertebral discs or joints. This method is designed to be used by operating room staff in a clinical setting to isolate a mesenchymal stem cell population and PHC during the same surgical procedure as transplantation. The method can be used as a two step procedure where cells are harvested, then isolated, then reimplanted at a later time. In addition, experimental techniques are described to determine which bone marrow cells should be removed via negative selection to generate a PHC population most likely to regenerate certain tissue types in-vitro as well as which combination of fibrinogen and hyaluronic acid and which degree of gel maceration provides the best matrix for in-vitro and in-vivo regeneration of joints and intervertebral discs. | 08-20-2009 |
| 20100168022 | Use of In-Vitro Culture to Design or Test Personalized Treatment Regimens - Provided herein are methods of assessing responsiveness to an agent, methods of customizing treatments, methods of screening agents, and methods of treatment. Also provided are systems and kits for carrying out the methods contemplated herein. An exemplary aspect includes a method of assessing whether a subject having a condition, disorder, dysfunction, or disease would respond to treatment with an agent. The method comprises obtaining a stem cell sample from the subject; culturing the sample; exposing the sample to an agent; evaluating the sample in the presence of and in the absence of the agent to create a sample profile; and comparing the sample profile to a reference profile indicative of responsiveness to the agent. The similarity between the sample profile and the reference profile indicates the subject's responsiveness to the agent. | 07-01-2010 |
Felicia Centeno, Chicago, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20110047969 | Post injection bucketing strategy to avoid hardware cavitation - An engine control system ( | 03-03-2011 |
Felicia V. Centeno, Chicago, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20080314371 | SYSTEM AND METHOD FOR DIESEL PARTICULATE FILTER REGENERATION - A method for regenerating a diesel particulate filter ( | 12-25-2008 |
Joseph Centeno, Kenosha, WI US
| Patent application number | Description | Published |
|---|---|---|
| 20080302617 | Railcar brake head - A railcar brake head having an upper end, a lower end, and a pair of sides. The brake head further includes an elongated concave keyway defining an elongated axis and opening to the upper and lower ends of the brake head. At least a portion of the keyway is defined between a rear wall and spaced transversely extending upper and lower lugs. A front surface of each lug is adapted for mounting engagement with a brake shoe. The longitudinal spacing between the centralized upper and lower lugs is such that a keybridge extending from a rear face of the brake shoe is received and accommodated therebetween whereby inhibiting endwise movement of the brake shoe relative to the brake head. The centrally disposed upper lug on the brake head is configured with a camming surface, a longitudinal portion of which is arranged relative to the keyway for guiding and facilitating movement of a free end of an elongated key downwardly past the upper lug whereby permitting the key to establish a proper locking relation with the keybridge of the brake shoe. | 12-11-2008 |
| 20100025170 | Railroad freight car brake beam assembly - A railroad freight car brake beam with a strut having a pair of generally parallel and joined side walls disposed to opposite sides of an axis of the strut and having a central hollow portion along with a longitudinally elongated slot adapted to be inclined a predetermined number of degrees from vertical for accommodating an elongated brake lever extending through the strut. Each side wall of the strut defines a bore opening to the hollow center portion and to an exterior of the strut. The bores defined by the strut are aligned relative to each other to accommodate at least a lengthwise portion of a brake lever pivot pin extending through the strut and serving to connect the brake lever to the strut. The aligned bores in the strut also define a pivot axis for the brake lever. The strut further includes a pair of bushings which journal the brake lever pivot pin. One bushing is accommodated in each bore defined by the strut. Cooperating instrumentalities inhibit inadvertent displacement of the brake pin bushings away from the axis of and relative to the strut thereby fixing the pivot axis of the brake lever relative to the strut. | 02-04-2010 |
Leo Centeno, East Palo Alto, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100249946 | TRANSCUTANEOUSLY ADJUSTABLE FLUID-FILLED IMPLANTS - Disclosed are implantable tissue augmentation devices, methods, and associated tools. The devices include an inflatable body, having a self-sealing membrane operably attached to a wall of the implant. The self-sealing membrane provides access for filling the device, and includes a first layer comprising a fabric. The fabric has a first plurality of yarn strands positioned in a first direction, and a second plurality of yarn strands positioned in a second direction. The first and second plurality of yarn strands intersect to form a matrix pattern with cells defined by free spaces between yarn strands. The membrane also includes a first elastomeric material configured to fill the cells as well as form a coating over the first and second plurality of yarn strand, and a second layer comprising a second elastomeric material. The second elastomeric material has a lower durometer than the first elastomeric material. Kits and systems are also disclosed. | 09-30-2010 |
| 20100249947 | POROUS IMPLANT WITH EFFECTIVE EXTENSIBILITY AND METHODS OF FORMING AN IMPLANT - The implant includes an outer layer of ePTFE which exhibits extensibility normally not associated with ePTFE. The ePTFE is reduced in length by deforming the fibrils between the nodes while maintaining the nodes in a substantially flat configuration. Various implant configurations that can include the outer layer described are also disclosed. | 09-30-2010 |