Caux
Brice Caux, Montjoire FR
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20140237869 | EXCAVATOR BUCKET AND EARTH MOVING MACHINE - The present disclosure relates to an excavator bucket for an earth moving machine comprising an interior bucket space formed by a curved rear wall and a pair of opposed sidewalls wherein the bucket comprises a bucket box arranged onto the rear wall, in particular arranged on the outer surface of its top portion, and which extends along a lateral axis of the bucket wherein the angle between at least one of the outer lateral sides of the bucket box and the rear wall of the bucket, in particular its top portion, is less than 90 degrees. | 08-28-2014 |
Christophe Caux, Lieu Dit Le Paillot FR
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20100086560 | CHEMOKINES AS ADJUVANTS OF IMMUNE RESPONSE - Dendritic cells play a critical role in antigen-specific immune responses. Materials and Methods are provided for treating disease states, including cancer, infectious diseases, autoimmune diseases, transplantation, and allergy by facilitating or inhibiting the migration or activation of a specific subset of antigen-presenting dendritic cells known as plasmacytoid dendritic cells (pDC). In particular, methods for treating disease states are provided comprising administration of chemokine receptor agonists and antagonists, alone or in combination with a disease-associated antigen, with or without an activating agent. | 04-08-2010 |
Christophe Caux, Bressolles FR
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20090087440 | Methods for Treating Cancer - Dendritic cells (DC) play a critical role in antigen-specific immune responses. Materials and Methods are provided for treating disease states, including cancer, by activating dendritic cells from the host which are rendered hypo-responsive to activation stimuli by the disease. In particular, methods are provided for treating cancer in a mammal comprising administering to said mammal an effective amount of a tumor-derived DC inhibitory factor antagonist in combination with an effective amount of a Toll-like receptor (TLR) agonist. | 04-02-2009 |
20120309013 | Use of the Combinatorial Diversity of T-Lymphocyte Repertoire as a Prognostic Marker of Cancer - The present invention relates to a method making it possible to identify the patients, from among those affected by a given solid cancer, that have increased risk of premature death. Said method is based on the ex vivo analysis of the lymphocytic diversity of the patients on the basis of a biological sample containing lymphocytes. In fact, low lymphocytic diversity is related to a poor prognosis. Specifically, it is possible to set a diversity threshold, depending on the analysis technology used and the cancer affecting the patient, beyond which the life expectancy of the patient is significantly less than that, in general, of the patients affected by the same disease. | 12-06-2012 |
Christophe Caux, Lyon Cedex 08 FR
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20140086923 | Antibodies Directed Against ICOS and Uses Thereof - The present invention provides antibodies directed against ICOS or a derivative thereof which neutralize ICOS engagement on Treg by inhibiting the fixation between ICOS and ICOS-L and abrogate proliferation of Treg induced by plasmacytoid dendritic cells. The present invention further provides antibodies directed against ICOS or a derivative thereof which induce IL-10 and IFNγ production, induce CD4+ T cells proliferation, reduce Tconv proliferation, and increase the immunosuppressive function of Treg. | 03-27-2014 |
Guylaine Caux, Sainte-Julie CA
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20160083953 | Fluid Backflow Management System and Method of Use Thereof - An apparatus for continuously controlling fluid flow in a sewer conduit, comprising: a) moisture sensors detecting levels of fluid in this conduit; b) an inflatable bladder, mounted in the sewer conduit for releasably sealing in fluid tight fashion a section of this conduit; a compressed air source for inflating the bladder; and a control box including a CPU sensitive to the moisture sensor(s) and actuating the air compressor responsively to conduit fluid level conditions reaching beyond a preset threshold value. The performance of the apparatus is independent of the speed of fluid flow in the sewer conduit. | 03-24-2016 |
Jocelyn Caux, La Pocatiere CA
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20120247689 | MAPLE WATER EVAPORATOR SYSTEM AND METHOD - A method and a system comprising pressurizing the vapor generated by evaporation, and circulating the pressurized vapor through the maple water above boiling temperature, so as to evaporate water from the maple water. As a result, once the steady state is reached, the main source of energy for water maple evaporation is the pressurized vapor, produced by a compressor. The compressor may be powered by an electrical or an internal combustion engine for example. The initial heating stage, needed to first get vapor from the maple water, is performed by an auxiliary heating unit, such as direct acting electrical heating elements, or a indirect heat source such as wood, oil, etc. for example. | 10-04-2012 |