| Patent application number | Description | Published |
|---|
| 20100075904 | Carbon nanotube composite scaffolds for bone tissue engineering - The present invention provides biocompatible composite materials that can be fabricated into a scaffold having properties suitable for bone repair and regeneration. These scaffolds have sufficient mechanical strength to be useful for the repair and regeneration of cortical bone. | 03-25-2010 |
| 20100249931 | MECHANICALLY COMPETENT NATURAL POLYMER BASED POROUS GRAFTS FOR BONE REPAIR AND REGENERATION - The invention provides a scaffold for bone or cartilage replacement, in which the scaffold is fabricated from naturally derived polymers. In one embodiment the invention provides a bone replacement scaffold, wherein the scaffold comprises sintered polysaccharide microspheres. In a particular embodiment the invention provides a bone replacement scaffold, in which the scaffold comprises polysaccharide microspheres comprising ethyl cellulose microspheres and/or cellulose acetate microspheres. The invention further includes methods of making bone replacement scaffolds and methods of treating bone injury in an animal. | 09-30-2010 |
| 20100298937 | MECHANICALLY COMPETENT SCAFFOLD FOR LIGAMENT AND TENDON REGENERATION - A multi-region device for repair, regeneration or reconstruction in articular tissue injury such as torn ligaments and tendons is provided. The device comprises at least one degradable material and biocompatible non-degradable polymeric fiber-based material, in a three-dimensional braided scaffold. The two end sections are designed for attachment of the device at the site of implantation and are designed to allow bone cell ingrowth, and one or more middle regions are designed to allow ligament or tendon cell ingrowth. | 11-25-2010 |
| 20100310623 | Synergetic functionalized spiral-in-tubular bone scaffolds - An integrated scaffold for bone tissue engineering has a tubular outer shell and a spiral scaffold made of a porous sheet. The spiral scaffold is formed such that the porous sheet defines a series of spiral coils with gaps of controlled width between the coils to provide an open geometry for enhanced cell growth. The spiral scaffold resides within the bore of the shell and is integrated with the shell to fix the geometry of the spiral scaffold. Nanofibers may be deposited on the porous sheet to enhance cell penetration into the spiral scaffold. The spiral scaffold may have alternating layers of polymer and ceramic on the porous sheet that have been built up using a layer-by-layer method. The spiral scaffold may be seeded with cells by growing a cell sheet and placing the cell sheet on the porous sheet before it is rolled. | 12-09-2010 |
