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Catherine M.

Catherine M. Amodeo, Livonia, MI US

Patent application numberDescriptionPublished
20110210596ONE-PIECE SEAT STRUCTURE AND COLD FORMING PROCESSES TO CREATE SEAT STRUCTURES - A one-piece seat structure for use in a vehicle seat assembly comprising a first portion having a first set of characteristics; a second portion having a second set of characteristics; wherein the first set of characteristics differs from the second set of characteristics and wherein the number of portions within the same one piece structure can be multiple; and wherein the one-piece seat structure is formed from a tailored welded blank or monolithic blank using a cold forming process with optional additional post forming processes including post form heat treatment, edge treatment, and the like.09-01-2011

Catherine M. Emerling, Salem, MA US

Patent application numberDescriptionPublished
20080258620Vibration resistent, energy efficient lamp - A vibration resistant, energy efficient lamp (10-23-2008

Catherine M. Gadlage, Duluth, GA US

Patent application numberDescriptionPublished
20110282254DECORATIVE CAST COVER - A cast cover includes a sleeve configured to be disposed over a cast; an aperture configured to receive the cast when pulling the sleeve over the cast; and a comfort band generally disposed about the aperture, wherein the comfort band is configured to be in physical communication with the skin of a cast wearer and covers an edge of the cast.11-17-2011

Catherine M. Kasubowski, Charlotte, NC US

Patent application numberDescriptionPublished
20090261005PACKAGE FOR A SAW BLADE OR SIMILAR PRODUCT - A package is provided for a saw blade that includes a paperboard back secured to a transparent plastic front. The plastic front includes an edge border that is reinforced to support the weight of the saw blade and that may extend over the edge of the paperboard back for the periphery thereof. The plastic front includes a pocket for receiving the blade where the pocket is provided with projections for engaging the blade to keep the blade from moving once inside the package. A peg is also provided in the plastic cover that engages a portion of the saw blade to ensure that the saw blade is properly oriented in the package during the packaging process. A portion of the back is not adhered to the plastic front to provide an easy opening access between the plastic front and the paperboard back.10-22-2009

Catherine M. Klapperich, Boston, MA US

Patent application numberDescriptionPublished
20100203521METHOD FOR BACTERIAL LYSIS - The present invention is directed to a microfluidic device for lysis of cells, such as bacteria and microorganisms. In particular, the present invention relates to microfluidic devices and methods of manufacture of such microfluidic devices comprising a substrate with at least one channel packed with a polymer monolith embedded with carbon particles, for example carbon nanotubes. The microfluidic devices and methods of the present invention are useful for cell lysis of cells within a biological sample, such as a untreated biological sample comprising microorganisms, such as but not limited to gram positive and gram negative bacteria. In some embodiments, the microfluidic devices of the present invention can also optionally comprise other modules enabling further processing of the biological sample, for example isolation, purification and detection of biomolecules released from the lysed cells, such as but not limited to nucleic acids or proteins or peptides from the lysed cells, providing a complete Lab-on-a-Chip analysis system for biomolecules released from difficult to lyse microorganisms in a single step or process. The microfluidic devices of the present invention can also be adapted and are useful to methods to enrich for microorganisms in a biological sample, for example enrich for a desired type of bacteria within a biological sample. The microfluidic devices and methods of the present invention can be adapted to perform highly efficient lysis of microorganisms within a biological sample for diagnostic tests, for example for diagnosis of infectious agents and pathogens, such as bacteria, viruses or parasites.08-12-2010

Catherine M. Shachaf, Palo Alto, CA US

Patent application numberDescriptionPublished
20090220415DIAGNOSTIC SYSTEM FOR THE DETECTION OF SKIN CANCER - Methods and compositions are provided for the analysis of skin surfaces to determine the presence of neoplastic tissue. In the methods of the invention, a composition comprising a florescent probe that binds to a specific neoplasia associated marker is applied topically to the area of interest. After topical administration, the probe preferentially binds to markers associated in neoplastic lesions in situ, which binding is detected with a compact illumination unit that provides illumination at a wavelength appropriate for image acquisition. The illumination unit comprises a light source and fiber optic bundle to direct the light towards the area of examination. A detection unit is used to capture and record an image of the area of investigation. The detection unit may be a digital camera, film camera, etc. A mapping module may also be provided to catalogue the site of examination.09-03-2009
20110311970COMPOSITIONS AND METHODS FOR INTRACELLULAR ANALYTE ANALYSIS - Compositions and methods for multiplex immunodetection of analytes in single cells or cell populations are described. The invention utilizes analytical nanotags (ANTs) each specific for a different target analyte (TA) species. Analytical nanotags typically comprise biocompatible composite organic-inorganic nanoparticles (bCOINs) that include probe molecules specific for a particular TA species. A plurality of ANTs each specific for a different TA species can be used in a single multiplex assay, including assays for analyzing intracellular analytes in living cells.12-22-2011

Catherine M. Smith, Carlsbad, CA US

Patent application numberDescriptionPublished
20100317022METHODS OF DIAGNOSING TISSUE FIBROSIS - The present invention provides a method of diagnosing the presence or severity of tissue fibrosis in an individual by detecting α2-macroglobulin (α2-MG) in a sample from the individual; detecting hyaluronic acid (HA) in a sample from the individual; detecting tissue inhibitor of metalloproteinases-1 (TIMP-1) in a sample from the individual; and diagnosing the presence or severity of tissue fibrosis in the individual based on the presence or level of α2-MG, HA and TIMP-1.12-16-2010

Catherine M. Tribouley, San Francisco, CA US

Patent application numberDescriptionPublished
20080241158Human taste-specific receptor TIR3 - The invention provides human G-protein coupled receptors (GCREC) and polynucleotides which identify and encode GCREC. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of GCREC.10-02-2008
20090274680Human Phospholipases - The invention provides human lipid metabolism enzymes (LME) and polynucleotides which identify and encode LME. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of LME.11-05-2009

Patent applications by Catherine M. Tribouley, San Francisco, CA US

Catherine M. Vefaillie, Leuven BE

Patent application numberDescriptionPublished
20120009672Methods for Differentiating Cells into Hepatic Stellate Cells and Hepatic Sinusoidal Endothelial Cells, Cells Produced by the Methods, and Methods for Using the Cells - The invention is directed to methods for culturing cells so that the cells are induced to differentiate into cells that express a hepatic stellate phenotype and cells that express a hepatic sinusoidal endothelial phenotype. The invention is also directed to cells produced by the methods of the invention. The cells are useful, among other things, for treatment of liver deficiency, liver metabolism studies, and liver toxicity studies.01-12-2012

Catherine M. Wiscount, Allentown, PA US

Patent application numberDescriptionPublished
20080287394Hiv Integrase Inhibitors - Hydroxy-substituted pyrazinopyrrolopyridazine dione compounds are inhibitors of HIV integrase and inhibitors of HIV replication. In one embodiment, the dione compounds are of Formula (I) wherein R11-20-2008
201000565161-HYDROXY NAPHTHYRIDINE COMPOUNDS AS ANTI-HIV AGENTS - 1-Hydroxy naphthyridine compounds (e.g., 1-hydroxy naphthyridin-2(1H)-one compounds of Formula I are inhibitors of HIV integrase and/or HIV RNase H and inhibitors of HIV replication: (I) wherein X and R1-R6 are as defined herein. The compounds are useful in the prophylaxis and treatment of infection by HIV and in the prophylaxis, delay in the onset, and treatment of AIDS. The compounds are employed against HIV infection and AIDS as compounds per se or in the form of pharmaceutically acceptable salts. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other anti-HIV agents such as HIV antivirals, immunomodulators, antibiotics and vaccines.03-04-2010

Patent applications by Catherine M. Wiscount, Allentown, PA US