| Patent application number | Description | Published |
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| 20090281464 | Medical treatment system including an ancillary medical treatment apparatus with an associated data storage medium - A medical treatment system includes an electronic controller with a medical treatment apparatus, a data reader, an ancillary treatment apparatus used with the electronic medical treatment apparatus and a data storage medium associated with the ancillary treatment apparatus. The controller is configured to receive information from the data storage medium, and to control the medical treatment apparatus with medical treatment parameters compatible with the desired medical treatment and the ancillary treatment apparatus. | 11-12-2009 |
| 20100331741 | Medical treatment system including an ancillary medical treatment apparatus with an associated data storage medium - A medical treatment system includes an electronic controller with a medical treatment apparatus, a data reader, an ancillary treatment apparatus used with the electronic medical treatment apparatus and a data storage medium associated with the ancillary treatment apparatus. The controller is configured to receive information from the data storage medium, and to control the medical treatment apparatus with medical treatment parameters compatible with the desired medical treatment and the ancillary treatment apparatus. | 12-30-2010 |
| 20110034832 | Usage of Extracorporeal and Intracorporeal Pressure Shock Waves in Medicine - A shock wave applicator includes a shock wave generator and an asymmetrical reflector portion in a housing. Asymmetry of the reflector portion is combined with one or more wave generators to produce a variety of focal volumes and wave fronts for medical treatment. | 02-10-2011 |
| 20110087157 | Use of Pressure Waves for Stimulation, Proliferation, Differentiation and Post-Implantation Viability of Stem Cells - Stem cells are proliferated with the application of acoustic pressure waves, including cambium cells of periosteum treated in-vivo with acoustic pressure waves. Following harvesting and viability assessment of in-vivo or in-vitro proliferated stem cells, acoustic pressure waves are applied to enhance in-vivo or in-vitro differentiation either before or after implantation of the stems cells to an organism. Acoustic pressure waves also stimulate an implantation site to enhance viability and to grow desired tissue. | 04-14-2011 |
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| 20080261967 | Modulators of Central Nervous System Neurotransmitters - Disclosed are agents having pharmacological activity against cellular receptors and intracellular signaling, particularly receptors and signaling pathways of central nervous system (CNS) neurotransmitters. Also disclosed are related methods and compositions for the treatment or prevention of diseases or disorders using the agents. | 10-23-2008 |
| 20100159596 | SMALL MOLECULE COMPOUNDS FOR STEM CELL DIFFERENTIATION - Methods and small molecule compounds for stem cell differentiation are provided. One example of a class of compounds that may be used is represented by the compound having the structure IA or IB in the form of free base or a pharmaceutically acceptable salt, hydrate, solvate or N-oxide thereof: | 06-24-2010 |
| 20110281356 | COMPOUNDS FOR STEM CELL DIFFERENTIATION - Methods and small molecule compounds for stem cell differentiation are provided. One example of a class of compounds that may be used is represented by the compound of Formula I: | 11-17-2011 |
| 20130123253 | MODULATORS OF CENTRAL NERVOUS SYSTEM NEUROTRANSMITTERS - Disclosed are agents having pharmacological activity against cellular receptors and intracellular signaling, particularly receptors and signaling pathways of central nervous system (CNS) neurotransmitters. Also disclosed are related methods and compositions for the treatment or prevention of diseases or disorders using the agents. | 05-16-2013 |
| Patent application number | Description | Published |
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| 20090263492 | Diagnostic Methods and Genetic Markers for Alzheimer Disease - Disclosed are methods for identifying individuals suffering from a CNS disorder (including Alzheimer's Disease, behavioral disorders, and the like) that could be treated with a CNS drug with greater therapeutic efficacy and lower side effects and the compounds useful for such treatment. Also disclosed are methods for predicting the efficacy of a drug candidate for the treatment of a CNS disorder. The technology is also applicable to drug discovery for use in animal models of neurodegenerative diseases. | 10-22-2009 |
| 20100190728 | Synthesis Of Metabolically Stable Analgesics, Pain Medications And Other Agents - Disclosed are analgesic-related compositions and methods of using the compositions for modulation of analgesic receptor activity. The compositions and methods are useful for reducing pain, as well as for therapeutic intervention of addictions or other diseases or disorders amenable to treatment or prophylaxis by modulation of analgesic receptor signaling. | 07-29-2010 |
| 20100298345 | SYNTHETIC COMPOUNDS AND DERIVATIVES AS MODULATORS OF SMOKING OR NICOTINE INGESTION AND LUNG CANCER - Disclosed are nicotine-related compounds that selectively inhibit cytochrome P-450 2A6 (CYP2A6), selectively inhibit cytochrome P-450 2A13 (CYP2A13), and/or selectively modulate a nicotinic acetylcholine receptor (nAChR). Also disclosed are pharmaceutical compositions comprising a compound of the invention, as well as methods of using the pharmaceutical compositions for treating or preventing a disease or disorder associated with nicotine-ingestion, or a disease or disorder amenable to treatment by selective modulation of nAChRs. | 11-25-2010 |
| 20110236931 | CHEMICAL AND BIOCHEMICAL ADDUCTS AS BIOMARKERS FOR ORGANOPHOSPHATE EXPOSURE - Provided is a method to identify OP-adducted biomarkers of OP exposure as well as compounds containing OPs that can provide OP adducts. | 09-29-2011 |
| 20110263630 | SYNTHESIS OF METABOLICALLY STABLE AGENTS FOR ALCOHOL AND DRUG ABUSE - Disclosed herein are compounds of formula (I); as defined herein, or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising the same, and methods of using these compounds for the treatment of substance addiction. | 10-27-2011 |
| 20120040976 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE - Disclosed are methods for identifying individuals suffering from a CNS disorder (including Alzheimer's Disease, ALS, behavioral disorders, and the like) that could be treated with a CNS drug with greater therapeutic efficacy and lower side effects and the compounds useful for such treatment. Also disclosed are methods for predicting the efficacy of a drug candidate for the treatment of a CNS disorder. The technology is also applicable to drug discovery for evaluation in animal models of neurodegenerative diseases. | 02-16-2012 |
| 20120196905 | SYNTHETIC COMPOUNDS AND METHODS TO DECREASE NICOTINE SELF-ADMINISTRATION - Methods and small molecule compounds for smoking and CNS disease harm reduction are provided. One example of a class of compounds that may be used is represented by the compound having the structure IA or IB in the form of free base or a pharmaceutically acceptable salt, hydrate or solvate thereof: | 08-02-2012 |
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| 20130124229 | SYSTEM AND METHOD FOR SECURE SELF REGISTRATION WITH AN INSURANCE PORTAL - Systems and methods are disclosed herein for processing a first-time registration request for electronic access to a plurality of computerized insurance services. A network interface is configured to communicate with the plurality of computerized insurance services by interfacing with a plurality of disparate information platforms and communicating with a user computing device. A memory stores a portal module, a profile module, and a security module, each in the form of computer executable instructions, which, when executed by a processor, cause the system to receive a user identity, a first-time registration request of the user identity, and one or more secure information items associated with the user identity from the user computing device, determine a verification score for the user identity based on the one or more secure information items, and selectively register the user identity with a plurality of the computerized insurance services based on the verification score. | 05-16-2013 |
| 20130125211 | SYSTEM AND METHOD FOR PROVIDING DYNAMIC INSURANCE PORTAL TRANSACTION AUTHENTICATION AND AUTHORIZATION - Systems and methods are disclosed herein for managing electronic access to a plurality of computerized insurance services. A network interface is configured to receive a user identity provided by a user remote to the system and an access request from the user to access a selected computerized insurance service from the plurality of computerized insurance services. A memory stores computer executable instructions which, when executed by a processor, cause the system to determine a set of access rights for the user based on the user identity and an insurance-related role associated with the user identity and allow the user to access the selected computerized insurance service according to the access request only if the access requested is included in the determined set of access rights. At least two of the computerized insurance services are implemented on substantially different information platforms. | 05-16-2013 |
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| 20100184838 | Compositions and methods for retinal transduction and photoreceptor specific transgene expression - Adenovirus (Ad) vectors are here provided for treatment of ocular tissues as are suitable methods to transduce photoreceptor (PR) cells, the tissue associated with degeneration. Expression from CMV or chicken beta actin (CBA) promoters in neural retina were compared, and CBA was found to be 173-fold more potent than CMV. Further, the RGD domain in Ad penton was found to play a key role in RPE tropism. Deletion of the RGD domain coupled with the CBA promoter permitted transgene expression in neural retina approximately 667-fold more efficiently than with prior Ad5 vectors. Use of Ad vectors in combination with a 4.7 kb rhodopsin promoter enabled transgene expression exclusively in photoreceptor cells in vivo. | 07-22-2010 |
| 20100209447 | Methods of making and using a cell penetrating peptide for enhanced delivery of nucleic acids, proteins, drugs, and adenovirus to tissues and cells, and compositions and kits - A peptide-POD with ability to penetrate and deliver fluorophores, siRNA, DNA and quantum dots to cells in culture and retinal and ocular tissues in vivo is provided herein. POD couples to adenovirus vectors, enhancing tropism for certain cells, potentially providing a safer and more efficacious method to deliver molecules to ocular and other tissues in vivo. POD constructs are therapeutic delivery vehicles for treating cells and tissues, including ocular cells and tissues suffering from retinal degeneration. | 08-19-2010 |
| 20110015136 | humanized model of membrane attack complex (MAC) formation on murine retina and compositions, kits and methods for treatment of macular degeneration - Methods and compositions for treating a subject having age-related macular degeneration (AMD), methods of assaying human macular degeneration (MD), and methods and kits for assaying potential therapeutic agents for treatment of human MD are provided herein. | 01-20-2011 |
