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Carreira

Erick Carreira, Zumikon CH

Patent application numberDescriptionPublished
20090186838Amphotericin Derivatives - The present invention provides new polyene macrolide derivatives which show very low toxicity while retaining high antifungal activity as compared with amphotericin B (AmB). These polyene macrolide derivatives comprise a polyene macrolide backbone having at least one free amino group, wherein the amino group is doubly alkylated with at least one hydrocarbon group carrying a total of at least two basic groups.07-23-2009
20090275524NOVEL HYPOCHOLESTEROLEMIC COMPOUNDS - The present invention relates to novel hypocholesterolemic compounds of formula (I) useful in the treatment and prevention of atherosclerosis and for the reduction of cholesterol levels as well as to pharmaceutical compositions comprising said compounds alone or in combination with other active agents11-05-2009
20110172464PROCESS FOR THE SYNTHESIS OF A PROPARGYLIC ALCOHOL - A process for the preparation of the compound of formula07-14-2011
20120029237Autocatalytic Process for the Synthesis of Chiral Propargylic Alcohols - An autocatalytic process for the synthesis of chiral propargylic alcohols.02-02-2012

Patent applications by Erick Carreira, Zumikon CH

Erick M. Carreira, Zurich CH

Patent application numberDescriptionPublished
20090054689PHOSPHORAMIDITE LIGAND AND PRODUCTION METHOD OF ALLYLIC AMINE USING THE SAME - The present invention provides a production method of an allylic amine represented by the formula (III):02-26-2009
20100016618CHIRAL IRIDIUM AQUA COMPLEX AND METHOD FOR PRODUCING OPTICALLY ACTIVE HYDROXY COMPOUND BY USING THE SAME - The invention relates to a chiral iridium aqua complex of formula (1):01-21-2010
20110054171PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE AMINES - Salts of optically active [4-(2-diphenylphosphanylnaphthalen-1-yl)phthalazin-1-yl]-(1-phenylethyl)amines represented by the formulas (1) to (4) with an optically active organic sulfonic acid, and a production method thereof.03-03-2011
20110137049CHIRAL IRIDIUM AQUA COMPLEX AND METHOD FOR PRODUCING OPTICALLY ACTIVE HYDROXY COMPOUND USING THE SAME - The invention provides a chiral iridium aqua complex which has good preservation stability, can be easily produced, and enables asymmetric transfer hydrogenation in a higher yield and with higher stereoselectivity. The chiral iridium aqua complex has the formula (1A):06-09-2011

Patent applications by Erick M. Carreira, Zurich CH

Joao Pedro Carreira, Pourriere FR

Patent application numberDescriptionPublished
20100283651CYCLIC DIGITAL TO ANALOG CONVERTER - Some embodiments include apparatus and methods having an amplifier, a capacitor network coupled to the amplifier, and switching circuitry coupled to the amplifier and the capacitor network. The switching circuit is configured to successively apply a selected reference voltage selected from among a first reference voltage, a second reference voltage, and a third reference voltage to the capacitor network in response to a digital input code to generate an output voltage. Additional embodiments are disclosed.11-11-2010

Raquel Sousa Carreira, San Diego, CA US

Patent application numberDescriptionPublished
20120042398COMPOSITIONS FOR LABELING AND IDENTIFYING AUTOPHAGOSOMES AND METHODS FOR MAKING AND USING THEM - The invention provides methods and compositions for detecting and measuring the amount of autophagosomes in cells or tissues, including biopsy samples, in vitro, in situ and/or in vivo. By detecting and measuring the amount of autophagosomes in cells or tissues, the methods and compositions of the invention also measure the amount of autophagic activity in a cell or a tissue. In one aspect, the invention can be adapted to a plate-reader format for high-throughput screening of drugs that modulate autophagy, i.e., high-throughput detection of autophagic (autophagosome) activity in cells or tissues. In alternative embodiments, the compositions of the invention can localize into autophagosomes (AV), and these compositions can comprise any detectable moiety or group, e.g., a cadaverine, a radioactive, fluorescent-, bioluminescent and/or paramagnetic-conjugated reagent.02-16-2012