Carpino
Elaina Carpino, Hebron, OH US
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20150218803 | ROOF INSULATION SYSTEMS - An insulation system includes roof sheathing panels, spaced apart structural members, a first insulation material, and a second insulation material. The first insulation material is disposed between pairs of the spaced apart structural members. The second insulation material is disposed across the spaced apart structural members and the first insulation material, such that both the spaced apart structural members and the first insulation material are covered by the second insulation material. | 08-06-2015 |
20150233110 | ROOF INSULATION SYSTEMS - An insulation system includes roof sheathing panels, spaced apart structural members, a first insulation material, and a second insulation material. The first insulation material is disposed between pairs of the spaced apart structural members. The second insulation material is disposed across the spaced apart structural members and the first insulation material, such that both the spaced apart structural members and the first insulation material are covered by the second insulation material. | 08-20-2015 |
Elaina M. Carpino, Hebron, OH US
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20120268586 | METHOD FOR ONLINE DETERMINATION OF CURE STATUS OF GLASS FIBER PRODUCTS - A method for assessing the cure status of a fibrous blanket manufactured with mineral fibers and binder is disclosed and comprises a using an online optical reflectance measurement as an assessment of cure status. The optical reflectance measurement may preferably be a color image taken of any surface, and in particular of a sectioned face, after which the image is optionally divided into multiple regions of interest (ROI) and analyzed for a color system variable that is representative of cure status. In some embodiments, the color system variable is the B value. Alternatively, the optical reflectance measurement may be UV or IR reflectance of a sectioned face. When two or more regions of interest are defined on a sectioned face, comparative information is valuable to assess cure at different levels, layers or portions of the interior of the fibrous product. | 10-25-2012 |
Giorgio Carpino, Naples IT
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20150272809 | ROBOTIC DEVICE FOR ASSISTANCE AND REHABILITATION OF LOWER LIMBS - The present invention refers to a robotic device for assistance and rehabilitation of lower limbs, in particular, an exoskeleton for supporting the walking of a human being. | 10-01-2015 |
Guido Carpino, Rome IT
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20110135610 | Multipotent stem cells from the extrahepatic biliary tree and methods of isolating same - The present invention relates to a multipotent stem cell, multipotent cell populations, and an enriched multipotent cell population, each found in fetal, neonatal, pediatric, and adult biliary tree tissue and up to 72 hours post mortem (although preferentially, within 10 hours post mortem) and capable of maturing into multiple endodermal tissues that include liver, biliary and pancreatic tissues. The multipotent stem/progenitor cell and cell populations are found in peribiliary glands, and progenitors descending from them are present throughout the biliary tree including in the gallbladder. High numbers of the peribiliary glands are found in the branching locations of the biliary tree such as hilum, common hepatic duct, cystic duct, common duct, common hepato-pancreatic duct and gallbladder. Related multipotent cells, multipotent cell populations and their descendent progenitors are found throughout the biliary tree including in the gall bladder, which does not have peribiliary glands. Compositions comprising same, methods of identifying and isolating same, maintaining same in culture, expanding same in culture and differentiating or lineage restricting the same in vitro or in vivo to hepatic, biliary or pancreatic fates (e.g., as hepatocytes, cholangiocytes, and/or pancreatic islet cells) are also provided. Methods of using the multipotent cells and/or multipotent cell populations are also provided. | 06-09-2011 |
20140301985 | METHOD OF TREATING PANCREATIC AND LIVER CONDITIONS BY ENDOSCOPIC-MEDIATED (OR LAPAROSCOPIC-MEDIATED) TRANSPLANTATION OF STEM CELLS INTO/ONTO BILE DUCT WALLS OF PARTICULAR REGIONS OF THE BILIARY TREE - A method of repairing diseased or dysfunctional pancreas or liver is provided. The method involves preparation of a suspension of stem cells and/or progenitor cells such as biliary tree stem cells, hepatic stem cells, pancreatic stem cells or their descendants, committed progenitor cells, from healthy tissue of the patient or of the biliary tree of a non-autologous donor and engrafting the cells into the wall of bile ducts near to the organ to be treated. The graft consists of stem cells or progenitors that are admixed with biomaterials and, optionally, with cytokines and/or native epithelial-mesenchymal cells appropriate for the maturational lineage stage of the cells to be engrafted. The cells are specifically introduced to the hepato-pancreatic common duct of the subject for treatment of pancreatic conditions or to the bile duct wall near to the liver for treatment of liver conditions and allowed to migrate to the pancreas or to the liver and expand and then rebuild part or the entirety of the diseased or dysfunctional organ. | 10-09-2014 |
20160058798 | METHOD OF TREATING PANCREATIC AND LIVER CONDITIONS BY ENDOSCOPIC-MEDIATED (OR LAPAROSCOPIC-MEDIATED) TRANSPLANTATION OF STEM CELLS INTO/ONTO BILE DUCT WALLS OF PARTICULAR REGIONS OF THE BILIARY TREE - A method of repairing diseased or dysfunctional pancreas or liver is provided. The method involves preparation of a suspension of stem cells and/or progenitor cells such as biliary tree stem cells, hepatic stem cells, pancreatic stem cells or their descendants, committed progenitor cells, from healthy tissue of the patient or of the biliary tree of a non-autologous donor and engrafting the cells into the wall of bile ducts near to the organ to be treated. The graft consists of stem cells or progenitors that are admixed with biomaterials and, optionally, with cytokines and/or native epithelial-mesenchymal cells appropriate for the maturational lineage stage of the cells to be engrafted. The cells are specifically introduced to the hepato-pancreatic common duct of the subject for treatment of pancreatic conditions or to the bile duct wall near to the liver for treatment of liver conditions and allowed to migrate to the pancreas or to the liver and expand and then rebuild part or the entirety of the diseased or dysfunctional organ. | 03-03-2016 |
Maximilan Carpino, Uncasville, CT US
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20130288873 | AMPLIFICATION AND ARRAY LOADING APPARATUS AND METHODS - An apparatus includes a robotic system providing movement in three orthogonal directions to an arm operable to receive a pipette tip and to facilitate movement of fluid into and out of the pipette tip. In addition, the apparatus can include a tray for receiving pipette tips, receptacles for receiving tubes, an apparatus for forming an emulsion, a device for forming particles that include copies of the polynucleotide, a device for enriching the particles and an apparatus for loading such particles onto a sensor array. The apparatus can further include receptacles for holding containers of reagent solutions. Optionally, the robot can include a gripper arm in addition to the pipette receiving arm. | 10-31-2013 |
Maximilian Carpino, Guilford, CT US
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20150057377 | POLYMER-BASED EMULSION BREAKING METHODS - A method for breaking emulsions includes applying a polymer mixture to an emulsion. The emulsion can be energized, such as through centrifugation or vibration. In particular, the polymer mixture can be in liquid form. The polymer mixture includes first and second liquid polymer, the second liquid polymer being less hydrophilic than the first liquid polymer. In a water-in-oil emulsion, the less hydrophilic polymer can preferentially reside within the oil phase. | 02-26-2015 |
Maximilian Carpino, Uncasville, CT US
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20130011880 | AUTOMATED ENRICHMENT FOR NUCLEIC ACID SEQUENCING - The present teachings provide apparatuses and methods for automated handling of samples, e.g., biological or chemical samples. The apparatuses and the methods of the present teachings allow automated performance of various sample manipulation steps without manual intervention. In a preferred embodiment, the present teachings provide apparatuses and methods for automated enrichment of templated beads produced by PCR. | 01-10-2013 |
20150087025 | METHOD AND APPARATUS FOR AUTOMATED SAMPLE MANIPULATION - The present teachings provide apparatuses and methods for automated handling of samples, e.g., biological or chemical samples. The apparatuses and the methods of the present teachings allow automated performance of various sample manipulation steps without manual intervention. In a preferred embodiment, the present teachings provide apparatuses and methods for automated enrichment of templated beads produced by PCR. | 03-26-2015 |
Philip A. Carpino, Newton, MA US
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20130123230 | 2-Thiopyrimidinones - Myeloperoxidase inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to treat, for example, cardiovascular conditions. | 05-16-2013 |
20130296351 | 2-Thiopyrimidinones - Myeloperoxidase inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to treat, for example, cardiovascular conditions. | 11-07-2013 |
20140288049 | 2-Thiopyrimidinones - Myeloperoxidase inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to treat, for example, cardiovascular conditions. | 09-25-2014 |
20150087585 | DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITORS - Derivatives of purine, 3H-imidazo[4,5-b]pyrimidine and 1H-imidazo[4,5-d]pyrazine of Formula I that inhibit the activity of the diacylglycerol acyltransferase 2 (DGAT2) and their uses in the treatment of diseases linked thereto in animals are described herein. | 03-26-2015 |
Sandro Carpino, Roma IT
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20160121137 | RADIOTHERAPY SYSTEM PROVIDED WITH A PROGRAM FOR THE CALCULATION OF THE INTENSITY OF AN ELECTRONS BEAM - A system for radiotherapy is described. The system includes an accelerator of an electron beam, an imaging apparatus, a control unit and a radiation dose sensor connected to the control unit equipped with a program configured to execute the steps: (i) setting a first intensity of the electron beam, according to a predefined image of a target zone, the intensity to be emitted in a first radiation; (ii) operating said accelerator to emit the first radiation being a fraction of the first intensity; (iii) detecting a real intensity during the first radiation by the radiation dose sensor; (iv) acquiring an image of the zone; (v) calculating an intermediate intensity according to the image acquired in the step (iv) and according to the real intensity; and (vi) comparing the first intensity with the intermediate intensity to calculate a final beam intensity for a subsequent second radiation | 05-05-2016 |