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Carpenter, CO
Bryan Carpenter, Loveland, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20080282226 | METHODS AND APPARATUS FOR DISPLAYING A DYNAMICALLY UPDATED SET OF TEST DATA ITEMS DERIVED FROM VOLATILE OR NONVOLATILE STORAGE - In one embodiment, a computer determines a plurality of data types associated with different ones of a plurality of test data items, and based on the determined data types, i) logs a first set of the plurality of test data items to volatile storage, and ii) logs a second set of the plurality of test data items to nonvolatile storage. The computer also monitors a current state of a graphical user interface (GUI). When the current state of the GUI is one of a first number of GUI states, the computer displays via the GUI, a dynamically updated set of test data items derived from the volatile storage. When the current state of the GUI is one of a second number of GUI states, the computer displays, via the GUI, a dynamically updated set of test data items derived from the nonvolatile storage. Other embodiments are also disclosed. | 11-13-2008 |
Bryan F. Carpenter, Loveland, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20080209441 | Context-driven dynamic subscription based on user selections - Methods and systems for allowing dynamic subscription updates by an event notification service are presented. | 08-28-2008 |
Danny Carpenter, Fort Morgan, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20110237358 | System, method and device for selecting a golf club - A system and device for selecting a golf club comprises a data entry means, an adjustment means, and a tag production means. A usage method is also disclosed. A golfer enters his or her individual data into the system via a computing device having software that accepts information about a golfer's shot distances, clubs, etc. The computing device manipulates and adjusts the data and creates customized shot distance chart information based on half, three-quarters and full swings of various golf clubs. A club selection card is produced which is inserted into a tag having a clear sleeve for viewing the card and a connection means to secure it to a golf bag. A usage method can comprise a golfer being presented with a particular shot situation; the golfer references the tag and selects an appropriate club from the information on the tag in order to make the shot. | 09-29-2011 |
Derrick T. Carpenter, Superior, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20110168667 | Anti-Reflective Surfaces And Methods For Making The Same - In an embodiment, a method of forming an anti-reflective surface includes providing conditions for a plasma, and exposing a surface of an organic-inorganic optical material to the plasma. A treated optical material formed thereby exhibits lower reflectivity relative to the material prior to the step of exposing, forming the anti-reflective surface. In an embodiment, a method of forming an anti-reflective surface includes depositing an etch mask on a surface of an optical material, providing plasma conditions for a plasma such that the plasma etches the optical material preferentially over the etch mask, and exposing the etch mask to the plasma using the plasma conditions to form a treated optical material having a plasma-affected zone. The optical material exhibits lower reflectivity relative to said optical material prior to the step of exposing, and forms the anti-reflective surface. | 07-14-2011 |
Eric I. Carpenter, Fort Collins, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20120072634 | FULLY INTEGRATED, LOW AREA UNIVERSAL SERIAL BUS DEVICE TRANSCEIVER - A transceiver apparatus includes a process, a first type of transceiver circuit for data transmission, a second type of transceiver circuit for data transmission, and a communications interface for communicating between the first type of transceiver circuit and an external device. The first type of transceiver circuit is co-located with a physical layer associated with the first type of transceiver circuit. In some embodiments, the first type of transceiver circuit can be, for example, a USB 2.0 transceiver circuit, and the second type of transceiver circuit can be a USB 3.0 transceiver circuit. The aforementioned external device can be an external USB device. | 03-22-2012 |
James Richard Carpenter, Colorado Springs, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20100148874 | METHODS AND SYSTEMS FOR STABILIZING AN AMPLIFIER - The invention generally relates to stabilizing an MRI power delivery system. In one aspect, a stabilization module that is in electrical communication with the MRI power delivery system is provided. The stabilization module includes a closed loop control system. The closed loop control system is used to modify the at least one characteristic of the input signal. The modified input signal is provided to the MRI power delivery system. | 06-17-2010 |
John Carpenter, Littleton, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20090185996 | HYDROXYETHYL STARCH-CONTAINING POLYPEPTIDE COMPOSITIONS - The invention provides compositions containing hydroxyethyl starch and polypeptides, including therapeutic polypeptides such as interleukin-11, that provide for enhanced stability of the polypeptide following storage at room temperature or elevated temperatures. | 07-23-2009 |
| 20090298743 | HYDROPHOBIC COMPOSITIONS CONTAINING RECONSTITUTION ENHANCER - Disclosed are compositions comprising a hydrophobic active agent, a polymer and a reconstitution enhancing agent. Reconstitution of the lyophilized form of the compositions takes less time than in the absence of the enhancing agent. | 12-03-2009 |
| 20100129379 | STABILIZED ANTIBODY FORMULATIONS AND USES THEREOF - The present invention provides methods of optimizing certain stable liquid formulations of antibodies that immunospecifically bind to antigens of interest. Such formulations are suitable for parenteral administration to a subject, and exhibit increased stability, low to undetectable levels of aggregation, low to undetectable levels of antibody fragmentation/degradation, and very little to no loss of the biological activities of the antibodies, even during long periods of storage. The methods of the invention provide formulations that offer multiple advantages over formulations produced by non-optimized methods, including less stringent or more readily available transportation and storage conditions, less frequent dosing, and/or smaller dosage amounts in the therapeutic, prophylactic and diagnostic uses of such formulations. The invention further provides methods of identifying antibodies exhibiting certain phase behaviors such that the antibodies can be formulated by the methods of the invention. Also provided are prophylactic, therapeutic, and diagnostic uses of such antibody formulations. | 05-27-2010 |
| 20110091415 | Hydroxyethyl Starch-Containing Polypeptide Compositions - The invention provides compositions containing hydroxyethyl starch and polypeptides, including therapeutic polypeptides such as interleukin-11, that provide for enhanced stability of the polypeptide following storage at room temperature or elevated temperatures. | 04-21-2011 |
John Carpenter, Denver, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20120070406 | THERAPEUTIC PROTEIN COMPOSITIONS HAVING REDUCED IMMUNOGENICITY AND/OR IMPROVED EFFICACY - The present invention provides methods for reducing and/or evaluating the immunogenic potential of a therapeutic protein preparation. The present invention further provides pharmaceutical compositions of therapeutic proteins and methods of treatment with the same, the compositions having low immunogenic potential and/or improved efficacy. The invention achieves these goals by evaluating therapeutic protein preparations for subvisible protein particulates, which can contribute significantly to the overall immunogenic potential of the protein preparation. Further, by maintaining the content of such subvisible protein particulates to below an immunogenic threshold level, the resulting pharmaceutical composition is less likely to result in a loss of tolerance (e.g., upon repeated administration), thereby improving both the safety and efficacy profile of the therapeutic. | 03-22-2012 |
John F. Carpenter, Littleton, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20080248522 | HIGH-PRESSURE INCLUSION BODY SOLUBILIZATION AND PROTEASE CLIPPING OF RECOMBINANT FUSION PROTEINS - Described herein are methods for the solubilization and proteolytic cleavage of fusion protein aggregates, including autocatalytic fusion proteins, at pressures greater than atmospheric pressure to yield soluble target polypeptides. | 10-09-2008 |
| 20080249286 | HIGH-PRESSURE REFOLDING OF PROTEINS IN THE PRESENCE OF BINDING PARTNERS - Methods for producing biologically active protein from aggregated and/or denatured proteins which comprise subjecting the protein to high hydrostatic pressure in the presence of a ligand or specific binding agent are disclosed. The ligand can be a macromolecule, such as another protein, a nucleic acid, or other macromolecules, or the ligand can be a small organic molecule. | 10-09-2008 |
| 20100075399 | METHODS FOR PROTEIN REFOLDING - The present invention discloses improved methods of disaggregating protein aggregates, and refolding denatured proteins, using high pressure. In particular, the present invention provides for the use of agitation, high temperature, “stepped” depressurization, dialysis and dilution under pressure to increase the speed and extent of aggregate dissolution and protein refolding. | 03-25-2010 |
| 20100158951 | Method of Preparing an Immunologically-Active Adjuvant-Bound Dried Vaccine Composition - The disclosure provides a method of preparing an immunologically-active adjuvant-bound freeze dried vaccine composition. A specific embodiment provides a stable vaccine composition comprising an aluminum-salt adjuvant, a recombinant | 06-24-2010 |
| 20100255536 | HIGH PRESSURE REFOLDING OF PROTEIN AGGREGATES AND INCLUSION BODIES - The present disclosure provides an effective method for the refolding of denatured proteins in solution so that properly folded, biologically active protein in solution is recovered in high yield. The refolding takes place at pressures between about 0.25 kbar to about 3.5 kbar, advantageously at about 1.5 kbar to about 3 kbar. Typically a chaotropic agent is present at a concentration which is not effective for denaturing protein at atmospheric pressure, and optionally, oxidation-reduction reagents can be incorporated in the refolding solution so that native intramolecular disulfide bonds can be formed where that is desired. The method is applicable to substantially all proteins, especially after solubilization and/or denaturation of insoluble protein aggregates, inclusion bodies, or abnormal oligomeric (soluble) aggregates. | 10-07-2010 |
| 20100330162 | Spray freeze dry of compositions for pulmonary adminstration - This invention provides methods and compositions to preserve bioactive materials, such as viruses, bacteria, cells, or liposomes, in freeze dried particles suitable for pulmonary administration. Methods provide spray freeze drying of formulations to form stable freeze dried particles. | 12-30-2010 |
| 20110046357 | HIGH PRESSURE REFOLDING OF PROTEIN AGGREGATES AND INCLUSION BODIES - The present disclosure provides an effective method for the refolding of denatured proteins in solution so that properly folded, biologically active protein in solution is recovered in high yield. The refolding takes place at pressures between about 0.25 kbar to about 3.5 kbar, advantageously at about 1.5 kbar to about 3 kbar. Typically a chaotropic agent is present at a concentration which is not effective for denaturing protein at atmospheric pressure, and optionally, oxidation-reduction reagents can be incorporated in the refolding solution so that native intramolecular disulfide bonds can be formed where that is desired. The method is applicable to substantially all proteins, especially after solubilization and/or denaturation of insoluble protein aggregates, inclusion bodies, or abnormal oligomeric (soluble) aggregates. | 02-24-2011 |
| 20110243996 | Spray freeze dry of compositions for intranasal administration - This invention provides methods and compositions to preserve bioactive materials, such as peptides, nucleic acids, viruses, bacteria, cells, or liposomes, in freeze dried particles suitable for intranasal administration. Methods provide spray freeze drying of formulations to form stable freeze dried particles for intranasal administration. | 10-06-2011 |
| 20120046225 | STABLE GLUCAGON FORMULATIONS FOR THE TREATMENT OF HYPOGLYCEMIA - The delivery of biopharmaceutical and other therapeutic agents parenterally to an animal via a minimally invasive, low pain administration is provided. The agents are delivered to the patient via, e.g., the epidermal, dermal, or subcutaneous layer of the skin in a concentrated form of injectable glucagon that is dissolved in a pharmaceutically acceptable carrier. | 02-23-2012 |
John Frank Carpenter, Littleton, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20110106044 | METHODS FOR EVALUATING THE AGGREGATION OF A PROTEIN IN A SUSPENSION INCLUDING ORGANOPOLYSILOXANE AND MEDICAL ARTICLES COATED WITH ORGANOPOLYSILOXANE CONTAINING A PROTEIN SOLUTION - This invention relates to methods for evaluating or inhibiting the aggregation of a protein in an aqueous suspension including organopolysiloxane and medical articles coated with organopolysiloxane containing a protein solution including sugar and a non-ionic surfactant. | 05-05-2011 |
William T. Carpenter, Vail, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20100158618 | METHOD OF MODIFYING THE AXIS OF ROTATION OF THE EARTH - A method of modifying the Earth-rotation vector relative to the body of the planet or in inertial space by redistribution of the Earth's mass. | 06-24-2010 |