Carla V.
Carla V. Finkielstein, Blacksburg, VA US
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20100285583 | COMPOUNDS AND METHODS FOR INHIBITING PLATELET AGGREGATION - The present invention relates to compounds and methods for inhibiting platelet aggregation. In an embodiment, the compound of the present invention contains the sulfatide binding region of the N-terminal phosphotyrosine binding domain (N-PTB) of Disabled-2 (Dab2). | 11-11-2010 |
20120264212 | COMPOUNDS AND METHODS FOR INHIBITING THE METASTASIS OF CANCER CELLS - The present invention relates to compounds and methods for inhibiting cancer metastasis. In an embodiment, the compound of the present invention contains the sulfatide binding region of the terminal phosphotyrosine binding domain (N-PTB) of Disabled-2 (Dab2). | 10-18-2012 |
Carla V. Rothlin, Del Mar, CA US
Patent application number | Description | Published |
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20100247554 | USE OF TAM RECEPTOR INHIBITORS AS ANTIMICROBIALS - This disclosure concerns antimicrobial compositions and methods for immunoenhancement, for example methods of increasing production of a type I interferon (IFN) in response to pathogen infection, by administration of a TAM receptor inhibitor. In certain embodiments, the disclosure concerns methods of using a TAM receptor inhibitor to treat a viral or bacterial infection in a subject. | 09-30-2010 |
20100266604 | USE OF TAM RECEPTOR INHIBITORS AS IMMUNOENHANCERS AND TAM ACTIVATORS AS IMMUNOSUPPRESSORS - This disclosure concerns compositions and methods for immunoenhancement and/or immunosuppression. In certain embodiments, the disclosure concerns methods of using a TAM receptor inhibitor for immunoenhancement, for example as a vaccine adjuvant, for the treatment of sepsis, or for treating an immunocompromised subject. Also disclosed are methods of screening for immunoenhancing agents. In other embodiments, the disclosure concerns methods of using a TAM receptor agonist for immunosuppression, for example as a treatment for an autoimmune disorder, for the treatment of an allergy, or for treating graft-versus-host disease in a subject. Also disclosed are methods of screening for immunosuppressive agents. | 10-21-2010 |
Carla V. Rothlin, New Haven, CT US
Patent application number | Description | Published |
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20130251734 | USE OF TAM RECEPTOR INHIBITORS AS ANTIMICROBIALS - This disclosure concerns antimicrobial compositions and methods for immunoenhancement, for example methods of increasing production of a type I interferon (IFN) in response to pathogen infection, by administration of a TAM receptor inhibitor. In certain embodiments, the disclosure concerns methods of using a TAM receptor inhibitor to treat a viral or bacterial infection in a subject. | 09-26-2013 |