Patent application number | Description | Published |
20100062077 | PYRROLO[1,2-A]IMIDAZOLEDIONE EFFECTIVE IN THE TREATMENT OF PERIPHERAL NEUROTOXICITY INDUCED BY CHEMOTHERAPEUTIC AGENTS - The use of a compound of formula (I), is disclosed in treating and/or preventing 5 chemotherapy-induced peripheral neurotoxicity (CIPN). The invention includes pharmaceutical compositions wherein the compound of formula (I) is present in a mixture with anticancer agents. An improved anticancer treatment with reduced CIPN-related side effects is also provided. | 03-11-2010 |
20100125096 | Acetam Derivatives for Pain Relief - The present invention provides a method of treatment, prevention and/or delay of progression of neuropathic pain by a specific dosing regime of acetam derivatives. | 05-20-2010 |
20100129469 | USE OF DIMIRACETAM IN THE TREATMENT OF CHRONIC PAIN - The use of dimiracetam in the treatment of chronic pain is disclosed. At doses higher than those previously disclosed in relation with its cognition enhancing activity (i.e. amelioration of learning and memory), dimiracetam was able to completely revert hyperalgesia or allodynia associated with several animal models of chronic pain. Dimiracetam showed high activity in iatrogenic neuropathies associated with antiviral and chemotherapeutic drug treatments and in painful conditions caused by osteoarthritis. In addition, dimiracetam was devoid of toxicity even at doses 10-fold higher than the highest therapeutic dose. The possibility of treating such debilitating pathologies with a highly effective and essentially non-toxic compound is therefore disclosed. | 05-27-2010 |
20110008473 | USE OF HYPERICUM PERFORATUM EXTRACTS IN THE TREATMENT OF NEUROPATHIC PAIN - Disclosed is the use of | 01-13-2011 |
20110015200 | NITROGEN-CONTAINING BYCYCLIC COMPOUNDS ACTIVE ON CHRONIC PAIN CONDITIONS - The invention refers to compounds of general formula (I) wherein the R groups are, independently, H, C | 01-20-2011 |
20110218249 | USE OF HYPERICUM PERFORATUM EXTRACTS IN THE TREATMENT OF NEUROPATHIC PAIN - Disclosed is the use of | 09-08-2011 |
20110251250 | USE OF DIMIRACETAM IN THE TREATMENT OF CHRONIC PAIN - The use of dimiracetam in the treatment of chronic pain is disclosed. At doses higher than those previously disclosed in relation with its cognition enhancing activity (i.e. amelioration of learning and memory), dimiracetam was able to completely revert hyperalgesia or allodynia associated with several animal models of chronic pain. Dimiracetam showed high activity in iatrogenic neuropathies associated with antiviral and chemotherapeutic drug treatments and in painful conditions caused by osteoarthritis. In addition, dimiracetam was devoid of toxicity even at doses 10-fold higher than the highest therapeutic dose. The possibility of treating such debilitating pathologies with a highly effective and essentially non-toxic compound is therefore disclosed. | 10-13-2011 |
20130072533 | COMPOUNDS WITH BOTH ANALGESIC AND ANTI-HYPERALGESIC EFFICACY - The present invention relates to molecules of formula (I), deriving from lipoic acid and camosine, their preparation and use as analgesics. | 03-21-2013 |