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Carla

Carla Baerg, Bellingham, WA US

Patent application numberDescriptionPublished
20090081625MATHEMATICS TEACHING AID - An apparatus and method for teaching involving teaching manipulatives. The teaching manipulative comprises a longitudinal rod having a plurality of multi-faced objects disposed upon its surface which are capable of substantially sliding along the length of the rod and have a unique object identifier disposed on each face. On either end of the rod is a stop member having a row identifier substantially in alignment with the unique identifiers on the faces of the multi-faced object.03-26-2009

Carla Bandeira, Voorhees, NJ US

Patent application numberDescriptionPublished
20090076509Dynamic cervical plate - A dynamic subsidence plate is described having a first plate member and a second plate member in sliding engagement that may infinitely subside between a first and second assembled position. The plate includes a lock assembly associated with the first and second plate members. The lock assembly includes a ramp portion, an interference portion, and a bearing member situated between the ramp portion and the interference portion. The lock assembly of the plate is configured to allow movement of the first member with respect to the second member in a first direction in an infinite number of positions between a first assembled position and a second assembled position. Further, the lock assembly alternatively prevents movement of the first member with respect to the second member in an opposite second direction between the first and second assembled positions.03-19-2009

Carla Baratta, Legnano (verona) IT

Patent application numberDescriptionPublished
20110014092GRADUAL-RELEASE DOSING DEVICE FOR SUBSTANCES IN DOMESTIC-USE APPARATUSES, IN THE PRESENCE OF WATER - A gradual-release dosing device (01-20-2011

Carla Byloos, Dresden DE

Patent application numberDescriptionPublished
20100266939Lithographic Mask and Method of Forming a Lithographic Mask - A lithographic mask comprises a first layer including grooves, a second layer including regions, sections and a groove-like structure that encloses the sections. The first and second layers are formed so as to reduce electrical potential differences within the second layer. A method of forming a lithographic mask includes forming first and second layers to dispose the second layer over the first layer, patterning the second layer to comprise sections, a region, and a groove-like structure enclosing the sections, and forming grooves in the first layer at portions not covered by the second layer. The first and second layers are formed to reduce potential differences within the second layers during the step of forming the grooves in the first layer.10-21-2010

Carla Caramella, Bologna IT

Patent application numberDescriptionPublished
20090081133Mucoadhesive xyloglucan-containing formulations useful in medical devices and in pharmaceutical fromulations - Mucoadhesive and controlled release formulations consisting of aqueous solutions containing 0.05% to 5% by weight of a natural purified polymer having xyloglucan structure and 10% to 70% by weight of glycerol. These formulations are suitable for the application on human mucous membranes, such as nasal, oral and vaginal mucous membranes, as moisturizing and softening agents or as pharmaceutical release system. Further objects of the invention are pharmaceutical formulations and medical devices suitable for the application to human mucous membranes, containing the mucoadhesive and controlled release formulations together with active ingredients and excipients.03-26-2009

Carla Cerami Hand, Chapel Hill, NC US

Patent application numberDescriptionPublished
20090004202METHODS FOR TREATMENT OF NEURODEGENERATIVE CONDITIONS BY PERIPHERALLY ADMINISTERED ERYTHROPOIETIN - Methods and compositions are provided for protecting or enhancing excitable tissue function in mammals by systemic administration of an erythropoietin receptor activity modulator, such as erythropoietin, which signals via an EPO-activated receptor to modulate the function of excitable tissue. Excitable tissues include central neuronal tissues, such as the brain, peripheral neuronal tissues, retina, and heart tissue. Protection of excitable tissues provides treatment of hypoxia, seizure disorders, neurodegenerative diseases, hypoglycemia, and neurotoxin poisoning. Enhancement of function is useful in learning and memory. The invention is also directed to compositions and methods for facilitating the transport of molecules across endothelial cell tight junction barriers, such as the blood-brain barrier, by association of molecules with an erythropoietin receptor activity modulator, such as an erythropoietin.01-01-2009

Carla Danussi, Udine IT

Patent application numberDescriptionPublished
20090202580METHOD FOR THE PREPARATION OF SPECIFIC ANTIBODIES AGAINST SACCHARIDIC ANTIGENS - The present invention relates to new compounds useful for the stimulation of the production of antibodies. Said compounds comprises a saccharidic tumor antigen and a polymeric scaffold. The present invention also encompasses conjugated compounds useful in ELISA assay for the selection of antibodies against saccharidic antigens.08-13-2009

Carla Degenhardt-Langelaan, Delft NL

Patent application numberDescriptionPublished
20120018628MATRIX FOR REAL-TIME AEROSOL MASS SPECTROMETRY OF ATMOSPHERIC AEROSOLS AND REAL-TIME AEROSOL MALDI MS METHOD - Matrix for real-time aerosol mass spectrometry of atmospheric aerosols and real-time aerosol MALDI MS method Abstract The invention is directed to a matrix material for MALDI mass spectrometry, to a matrix composition for MALDI mass spectrometry, in particular for aerosol MALDI mass spectrometry, to a MALDI mass spectrometry method, in particular an aerosol MALDI mass spectrometry method, to the use of a specific compound as a MALDI matrix material, and to the use of a MALDI matrix composition in a gas phase coating method. The matrix material of the invention comprises a 2-mercapto-4,5-dialkylthiazole according to formula (I), wherein X is chosen from S, O or N, and wherein R01-26-2012

Carla Delannoy, Chexbres CH

Patent application numberDescriptionPublished
20100297329SPREADABLE DAIRY PRODUCT - The invention concerns a shelf stable spread that includes sweetened condensed milk of fat content 2 to 25% by weight and water content 15 to 35% by weight and at least one organoleptic modifying food substance added at a ratio ranging from 2% to 30% by weight and preferably 5% to 15% by weight wherein the spread is substantially free of emulsifiers and thickeners, is not caramelised and is thickened by shear so that it has a firmness corresponding to a maximum compression force of at least 20 g measured at 25° C. by a Texture Analyser equipped with a 5 kg load cell and a 20 mm diameter cylinder probe with a penetration into the sample at a constant speed 1 mm/s during 10 s.11-25-2010

Carla De Young, Joliet, IL US

Patent application numberDescriptionPublished
20090139776Scale - The scale may include a base supportable on a surface, a measuring mechanism supported by the base and operable to measure a characteristic of an object, the measuring mechanism including a measuring platform on which the object is supportable, and an indicator supported by the housing, the indicator being operable to provide feedback to a user relating to a measured characteristic of the object. In some aspects, the scale may include a housing supported by the base, the housing cooperating with the base to cover at least a portion of the measuring mechanism, and a connecting assembly operable to removably connect the housing to the base. In some aspects, the scale may include a resistance device coupled to at least one of the indicator and the measuring mechanism and operable to resist oscillation of the indicator at least one of during a measurement and after a measurement. In some aspects, the scale may include a cylinder supported by the housing, and a piston connected to the platform for movement with the platform, the piston engaging the cylinder to provide a piston and cylinder assembly, the assembly being operable to resist movement of the platform at least one of during a measurement and after a measurement.06-04-2009

Carla Duymelinck, Kruibeke BE

Patent application numberDescriptionPublished
20080206807Methods, Reagents, Devices and Instrumentation For Preparing Impregnated Tissue Samples Suitable For Histopathological and Molecular Studies - A process for the production of paraffin sections of biological tissue, especially for molecular pathology studies is disclosed. In the process, the tissue sample is simultaneously fixed, dehydrated and cleared in a first step, subsequently dehydrated and cleared in a second step and infiltrated with an inert specimen matrix in a third step. The specimen can then be further embedded in a casting supporting matrix according to the standard procedures followed by any local pathology or research laboratory. A kit and a processing station for automating paraffin embedding of a tissue sample suitable for histopathological and molecular analysis is also described. A bio-indicator system is described for measuring the degree of crosslinking. A tissue sample holding means or a vial which includes a tissue sample holding means provided with a data logging device capable of registering and transmitting data regarding the sample and conditions where the sample was processed is also disclosed.08-28-2008
20080274496Methods, Reagents and Instrumentation for Preparing Impregnated Tissue Samples Suitable for Histopathological and Molecular Studies - A process and kit for the production of paraffin sections of biological tissue, especially for molecular pathology studies, is described. In the process, the tissue sample is simultaneously fixed, dehydrated and cleared in a first step, subsequently dehydrated and cleared in a second step and infiltrated with an inert specimen matrix in a third step. The specimen can then be further embedded in a casting supporting matrix according to the standard procedures followed by any local pathology or research laboratory. The method is uncomplicated, requires little hands-on time, is reproducible and is standardized thereby limiting cross-centre pre-analytical variance. A bio-indicator system for measuring the degree of crosslinking is also disclosed.11-06-2008

Carla Ferragina, Roma IT

Patent application numberDescriptionPublished
20110245513SYNTHESIS PROCESS OF POLYOL CARBONATE FROM POLYOLS, CONDUCTED IN USING A SOLVENT SELECTIVE FOR POLYOLS CARBONATES - The present invention relates to a synthesis process of polyol carbonate, such as glycerol carbonate, from polyols such as glycerol, propylene glycol or ethylene glycol and urea conducted in using a solvent selective for polyols (glycerol) carbonates. Said process comprises reacting polyol with urea in the presence of a catalyst, extracting produced NH10-06-2011

Carla Ghelardini, Pistoia IT

Patent application numberDescriptionPublished
20100062077PYRROLO[1,2-A]IMIDAZOLEDIONE EFFECTIVE IN THE TREATMENT OF PERIPHERAL NEUROTOXICITY INDUCED BY CHEMOTHERAPEUTIC AGENTS - The use of a compound of formula (I), is disclosed in treating and/or preventing 5 chemotherapy-induced peripheral neurotoxicity (CIPN). The invention includes pharmaceutical compositions wherein the compound of formula (I) is present in a mixture with anticancer agents. An improved anticancer treatment with reduced CIPN-related side effects is also provided.03-11-2010
20100125096Acetam Derivatives for Pain Relief - The present invention provides a method of treatment, prevention and/or delay of progression of neuropathic pain by a specific dosing regime of acetam derivatives.05-20-2010
20100129469USE OF DIMIRACETAM IN THE TREATMENT OF CHRONIC PAIN - The use of dimiracetam in the treatment of chronic pain is disclosed. At doses higher than those previously disclosed in relation with its cognition enhancing activity (i.e. amelioration of learning and memory), dimiracetam was able to completely revert hyperalgesia or allodynia associated with several animal models of chronic pain. Dimiracetam showed high activity in iatrogenic neuropathies associated with antiviral and chemotherapeutic drug treatments and in painful conditions caused by osteoarthritis. In addition, dimiracetam was devoid of toxicity even at doses 10-fold higher than the highest therapeutic dose. The possibility of treating such debilitating pathologies with a highly effective and essentially non-toxic compound is therefore disclosed.05-27-2010
20110008473USE OF HYPERICUM PERFORATUM EXTRACTS IN THE TREATMENT OF NEUROPATHIC PAIN - Disclosed is the use of 01-13-2011
20110015200NITROGEN-CONTAINING BYCYCLIC COMPOUNDS ACTIVE ON CHRONIC PAIN CONDITIONS - The invention refers to compounds of general formula (I) wherein the R groups are, independently, H, C01-20-2011
20110218249USE OF HYPERICUM PERFORATUM EXTRACTS IN THE TREATMENT OF NEUROPATHIC PAIN - Disclosed is the use of 09-08-2011
20110251250USE OF DIMIRACETAM IN THE TREATMENT OF CHRONIC PAIN - The use of dimiracetam in the treatment of chronic pain is disclosed. At doses higher than those previously disclosed in relation with its cognition enhancing activity (i.e. amelioration of learning and memory), dimiracetam was able to completely revert hyperalgesia or allodynia associated with several animal models of chronic pain. Dimiracetam showed high activity in iatrogenic neuropathies associated with antiviral and chemotherapeutic drug treatments and in painful conditions caused by osteoarthritis. In addition, dimiracetam was devoid of toxicity even at doses 10-fold higher than the highest therapeutic dose. The possibility of treating such debilitating pathologies with a highly effective and essentially non-toxic compound is therefore disclosed.10-13-2011

Carla Ghelardini, Firenze IT

Patent application numberDescriptionPublished
20090163565Compounds with nootropic action, their preperation, pharmaceutical compositions containing them, and use thereof - Described herein are new bicyclic arylimidazolones having nootropic action (i.e., protecting and stimulating cerebral functions), analgesic action and anti hyperalgesic action; also described is the process for their preparation and pharmaceutical compositions comprising them, useful for the treatment of cognitive deficits, and of various types of pain.06-25-2009
20100173945Compounds with nootropic action, their preparation, pharmaceutical compositions containing them, and use thereof - Described herein are new bicyclic arylimidazolones having nootropic action (i.e., protecting and stimulating cerebral functions), analgesic action and anti hyperalgesic action; also described is the process for their preparation and pharmaceutical compositions comprising them, useful for the treatment of cognitive deficits, and of various types of pain.07-08-2010

Carla Grandori, Seattle, WA US

Patent application numberDescriptionPublished
20110166200METHODS OF USING MIR210 AS A BIOMARKER FOR HYPOXIA AND AS A THERAPEUTIC AGENT FOR TREATING CANCER - The present invention provides compositions and methods for predicting the hypoxia response in tumor cells, methods for predicting the likelihood of cancer metastasis, and methods for inhibiting tumor cell proliferation using a microRNA comprising miR-210.07-07-2011

Carla Green, Shawnee, OK US

Patent application numberDescriptionPublished
20100257674Method for positioning a human subject for radiological imaging, surgery or minimally invasive procedures using an inflatable contoured pillow - An ergonomic pillow for supporting and positioning a human subject on an imaging table having one or more inflatable chambers, and methods of use.10-14-2010

Carla Knoop, Stuttgart NL

Patent application numberDescriptionPublished
20080301587Control System for a Motor Vehicle - A control system for a motor vehicle having a manual operating means having a plurality of adjustment degrees of freedom for selecting and/or activating entries in a menu structure having a plurality of menu levels, and a screen display (12-04-2008

Carla Lanuza Cerzocimo, Huesca ES

Patent application numberDescriptionPublished
20110313321METHOD AND DEVICE FOR OBTAINING A PLANTAR IMAGE AND DOUBLE-SIDED MACHINING OF THE INSOLE THUS OBTAINED - Method for obtaining a plantar image using means for securing and tightening an elastic membrane, as well as to the double-sided machining of the obtained insole, said means taking the form of two adjustable horizontal bars positioned on a scanner or a plurality of cameras and an anti-reflective lens, wherein a membrane is positioned between said horizontal bars and secured using T-flat bars; the stress of the membrane being adjusted using a handle; the foot is positioned on the membrane; an image is taken; and the insole is subjected to double-sided machining on the basis of the image of the surface provided in STL format, with the aid of a securing device that enables the pieces to be rotated up to 12-22-2011

Carla Lintas, Rome IT

Patent application numberDescriptionPublished
20100227324MEASUREMENT OF ARYLESTERASE ENZYMATIC ACTIVITY AND ASSESSMENT OF GENETIC POLYMORPHISMS LOCATED IN THE PON1 GENE AS A DIAGNOSTIC TOOL IN AUTISM-SPECTRUM DISORDERS - The present invention concerns a method for detecting the presence of or predisposition to autism, an autism spectrum disorder, or an autism-associated disorder in a subject, the method comprising measuring an arylesterase enzymatic activity in a sample from the subject, optionally combined with the determination of alleles of PON1 polymorphisms.09-09-2010

Carla Mann Woods, Beverly Hills, CA US

Patent application numberDescriptionPublished
20090248096OPERATING ROOM LEAD CONNECTOR - An operating room connector is used in conjunction with a multiple electrode SCS system which can easily detach and connect to an external trial stimulator (ETS). By connecting the electrode SCS system to a stylet handle, and then locking the stylet handle within a slot of the connector platform, a user is able to minimize the required steps in connecting the ETS to the implanted SCS lead system. The ETS can then be used to readjust the position of the electrode array(s) previously implanted to deliver an optimal stimulation therapy.10-01-2009
20100046778INTEGRATED COCHLEAR IMPLANT HEADPIECE - An integrated headpiece for a cochlear implant system includes a microphone for outputting an audio signal; signal processing electronics for processing the audio signal; and a transmitter for transmitting a processed audio signal received from the electronics to an implanted receiver. All of the microphone, signal processing electronics, and transmitter are disposed in a common housing of the integrated headpiece. The headpiece may also be one of a set of headpieces that can be alternatively used as needed to suit power consumption requirements or environmental conditions.02-25-2010
20100046779MODULAR SPEECH PROCESSOR HEADPIECE - A cochlear implant system includes: an electrode array implanted within a cochlea; an internal processor in communication with the electrode array; an implanted antenna which is electrically coupled to the internal processor; and a modular external headpiece which is removably positioned over the implanted antenna, the modular external headpiece including a core containing a sound processor for processing sound and providing a corresponding signal to the implanted antenna; and a modular component configured to releasably engage the core and supply electrical power to the core. A modular speech processor headpiece includes a core comprising a microphone and sound processor for producing a signal representing ambient sound to be transmitted to a cochlear implant, the core further comprising a number of electrical contacts; and a modular component containing a number of electrical contacts corresponding to the electrical contacts of the core; wherein the core is configured to engage with the modular component such that electrical communication is made between the core and the modular component.02-25-2010
20100280572OPEN LOOP DEEP BRAIN STIMULATION SYSTEM FOR THE TREATMENT OF PARKINSON'S DISEASE OR OTHER DISORDERS - A deep brain stimulation (DBS) system (11-04-2010

Patent applications by Carla Mann Woods, Beverly Hills, CA US

Carla Mcnearny, Arvada, CO US

Patent application numberDescriptionPublished
20100262550INTER-CORPORATE COLLABORATION OVERLAY SOLUTION FOR PROFESSIONAL SOCIAL NETWORKS - A service provider includes a broker. The broker receives a request from a business organization requester for one or more potential collaborators in a determined subject matter area; accesses one or more personal profiles maintained by one or more social network services; selects a subset of individuals described in the accessed profiles as being of potential interest to the requester; and provides to the requestor information describing the members of the subset of individuals.10-14-2010

Carla Minarini, Salerno IT

Patent application numberDescriptionPublished
20090066244Encapsulated Organic Electronic Device With Improved Resistance To Degradation - An encapsulated organic electronic device is provided with: a substrate; at least one first elementary component and one second elementary component set above the substrate, each of said first and second elementary components being provided with a respective first electrode set above the substrate, a respective region of organic material set above the first electrode, and a respective second electrode set above the region of organic material at least partially in an area corresponding to the first electrode; and an encapsulation structure, defining an encapsulation space isolated from an external environment and designed to protect the first and second elementary components from the external environment. In particular, the regions of organic material of the first and second elementary components are separated and distinct from one another and are set entirely within the encapsulation space.03-12-2009

Carla Miner, Carp CA

Patent application numberDescriptionPublished
20090046222Electroluminescent Films for Backlighting Liquid Crystal Displays - The present invention replaces the conventional cold cathode fluorescent tubes used in backlighting units of liquid crystal displays with an integrated electro-luminescent film structure, subdivided into electrically isolated micro-panels. Ideally, the electro-luminescent structure comprises separate red, green and blue micro-panels providing full color capabilities. Alternatively, the electro-luminescent film structure includes stacked groups of layers, in which each group emits a different color and is independently controllable.02-19-2009
20100032687ENGINEERED STRUCTURE FOR HIGH BRIGHTNESS SOLID-STATE LIGHT EMITTERS - Electroluminescent (EL) light emitting structures comprises one or more active layers comprising rare earth luminescent centres in a host matrix for emitting light of a particular colour or wavelength and electrodes for application of an electric field and current injection for excitation of light emission. The host matrix is preferably a dielectric containing the rare earth luminescent centres, e.g. rare earth doped silicon dioxide, silicon nitride, silicon oxynitrides, alumina, dielectrics of the general formula Si02-11-2010
20100033111ELECTROLUMINESCENT FILMS FOR BACKLIGHTING LIQUID CRYSTAL DISPLAYS - The present invention replaces the conventional cold cathode fluorescent tubes used in backlighting units of liquid crystal displays with an integrated electro-luminescent film structure, subdivided into electrically isolated micro-panels. Ideally, the electro-luminescent structure comprises separate red, green and blue micro-panels providing full color capabilities. Alternatively, the electro-luminescent film structure includes stacked groups of layers, in which each group emits a different color and is independently controllable.02-11-2010
20110024819HIGH QUALITY GATE DIELECTRIC FOR SEMICONDUCTOR DEVICES AND METHOD OF FORMATION THEREOF - Improved high quality gate dielectrics and methods of preparing such dielectrics are provided. Preferred dielectrics comprise a rare earth doped dielectric such as silicon dioxide or silicon oxynitride. In particular, cerium doped silicon dioxide shows an unexpectedly high charge-to-breakdown Q02-03-2011

Patent applications by Carla Miner, Carp CA

Carla Nelson, Burnsville, MN US

Patent application numberDescriptionPublished
20100325087TEST STRATEGY SYSTEM AND METHOD FOR ACCOUNTS HELD DIRECT AT-FUND - The present invention provides a system and method for a user to test and transfer data from a client's database or network to a host's database or network. In accordance with an exemplary embodiment of the present invention, a user acquires data information from a client. The user uses this information to generate a spreadsheet, and to populate the spreadsheet with assumed values based on the information received from the client. The spreadsheet is configured in a fashion such that it is consistent with the host's database or network. The user requests and receives a test file from the client and uses a developed algorithm, generally in the form of a computer program, to reformat the file so that it is consistent with the host's database configuration. The user determines the consistency between the reformatted file and the host's database by comparing the reformatted file to the previously generated spreadsheet. Any inconsistencies identified alert the user that the file reformatting algorithm needs updating. When all the updates are complete and the reformatting algorithm has been deemed appropriate to carry out the data transformation function, the entire client database log is sent to the user in the form of an input file. The input file is duplicated to protect the original information and then reformatted using the updated algorithm. The reformatted file may then be uploaded to the host's network or database so that the information contained may be used by others who access the database or network for information.12-23-2010
20120011154TEST STRATEGY SYSTEM AND METHOD FOR ACCOUNTS HELD DIRECT AT-FUND - A system and method for a user to test and transfer data from a client's database or network to a host's database or network is disclosed. A user acquires data information from a client and the user uses this information to generate a spreadsheet, and to populate the spreadsheet with assumed values based on the information received from the client. The user requests and receives a test file from the client and uses a developed algorithm to reformat the file so that it is consistent with the host's database configuration. The user determines the consistency between the reformatted file and the host's database by comparing the reformatted file to the previously generated spreadsheet. Any inconsistencies identified alert the user that the file reformatting algorithm needs updating.01-12-2012

Patent applications by Carla Nelson, Burnsville, MN US

Carla Oncins Bergas, Barcelona ES

Patent application numberDescriptionPublished
20110195103COSMETIC OR DERMOPHARMACEUTICAL COMPOSITION CONTAINING PSEUDOALTEROMONAS FERMENT EXTRACT - Cosmetic or dermopharmaceutical compositions containing 08-11-2011

Carla Peinknagura, Menlo Park, CA US

Patent application numberDescriptionPublished
20080208213Devices and methods for the controlled formation and closure of vascular openings - The present invention includes systems, devices and methods for percutaneously forming an aperture within a tissue structure or vessel and closing the aperture in a manner which optimizes hemostasis and healing. The invention in one aspect includes implantable devices which are used to seal the tissue aperture upon closure of the aperture after a percutaneous or endovascular procedure.08-28-2008

Carla Pienknagura, San Carlos, CA US

Patent application numberDescriptionPublished
20090291196Abluminal Stent Coating Apparatus And Method Using A Brush Assembly - The apparatus and method use an optical feedback system to align a brush assembly with a stent strut. Once alignment is achieved, a coating is dispensed onto the stent strut via the brush assembly and the brush assembly is moved along the stent strut to coat the stent strut.11-26-2009

Carla Samolej, Bolingbrook, IL US

Patent application numberDescriptionPublished
20110011989Holder for flexible elongate conduits - A holder for securing flexible elongate conduits to a post includes a first holding member defined by first and second arms that extend from a first base and a second holding member defined by third and fourth arms that extend from a second base. The first and second bases are attached to one another. A first plane generally bisects the first holding member and is generally equidistant from the first and second arms along an entire longitudinal extent of the first holding member. A second plane generally bisects the second holding member and is generally equidistant from the third and fourth arms along an entire longitudinal extent of the second holding member. The first and second planes are generally perpendicular.01-20-2011

Carla Sibella, Paris FR

Patent application numberDescriptionPublished
20110312006Enzymatic Assay for the Quantitative Determination of Phospholipase A1 or A2 Activity in a Sample - The invention relates to a new method for measuring a calcium-dependent phospholipase A1 or A2 enzymatic activity in a sample, comprising the following steps: a) contacting said sample with a solid phase coated with a fluorochrome-labelled phospholipase A1 or A2 substrate, wherein the molecular coverage is in the range 8 to 30 fluorochrome-labelled phospholipase A1 or A2 substrate molecules/nm2 in conditions where calcium-dependent phospholipase A1 or A2 enzymatic activity is blocked. b) reading the fluorescence emission overtime c) adding a solution to initiate calcium-dependent phospholipase A1 or A2 enzymatic activity d) reading the fluorescence emission overtime, and kits for carrying out said method.12-22-2011
20110312008Enzymatic Assay for the Quantitative Determination of Phospholipase A1 or A2 Activity in a Sample - The invention relates to a new method for measuring phospholipase A1 or A2 activity in a sample, using a solid phase coated with a fluorochrome-labelled phospholipase A1 or A2 substrate, wherein the molecular coverage is in the range from 8 to 30 fluorochrome-labelled phospholipase A1 or A2 substrate molecules/nm2, and kit for carrying out said method.12-22-2011

Carla Stacchino, Torino IT

Patent application numberDescriptionPublished
20080249619CARDIAC-VALVE PROSTHESIS - A cardiac-valve prosthesis which can be used, for example, as a valve for percutaneous implantation. The prosthesis includes an armature for anchorage of the valve prosthesis in the implantation site. The armature defines a lumen for passage of the blood flow and supports a set of prosthetic valve leaflets, which, under the action of the blood flow, are able to move into a radially divaricated condition to enable the flow of the blood through the lumen in a first direction and a radially contracted condition, in which the valve leaflets co-operate with one another and block the flow of the blood through the prosthesis in the opposite direction. The armature includes, in one embodiment, two annular elements connected by anchor members having the capacity of projecting radially with respect to the prosthesis, and support members for the set of leaflets, the support members being carried by at least one of the annular elements so as to leave substantially disengaged the aforesaid lumen for passage of the blood.10-09-2008
20080255662MINIMALLY-INVASIVE CARDIAC-VALVE PROSTHESIS - A cardiac-valve prosthesis is adapted for percutaneous implantation. The prosthesis includes an armature adapted for deployment in a radially expanded implantation position, the armature including a support portion and an anchor portion, which are substantially axially coextensive with respect to one another. A set of leaflets is coupled to the support portion. The leaflets can be deployed with the armature in the implantation position. The leaflets define, in the implantation position, a flow duct that is selectably obstructable. The anchor portion can be deployed to enable anchorage of the cardiac-valve prosthesis at an implantation site.10-16-2008
20080262603PROSTHETIC HEART VALVE HOLDER - A holder for prosthetic heart valves including an annular base and prosthetic valve leaflets extending between commissure regions oriented axially with respect to the base. The holder includes a grip element from which a plurality of arms extend for supporting the prosthetic heart valve in an intermediate position between the commissures. Protecting formations extend radially with respect to the grip element to protect the commissure regions. The grip element includes a first rotational element for coupling to a handle and at least one second coupling element for coupling the grip element of the holder to a support element thereby impeding its rotation.10-23-2008

Patent applications by Carla Stacchino, Torino IT