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Carinci

Francesco Carinci, London GB

Patent application numberDescriptionPublished
20090270997USE OF NANOMATERIALS BASED ON TITANIUM DIOXIDE AND ZIRCONIUM DIOZIDE AS COATINGS FOR OSTEOINTEGRATED BIOMEDICAL PROSTHESES, AND OSTEOINTEGRATED BIOMEDICAL PROSTHESES PREPARED THEREWITH - The present invention proposes novel materials and methods, for preparation of coatings based on titanium dioxide for osteointegrated biomedical prostheses. The coatings are realized with nanomaterials having antibacterial properties, and have the purpose of: promoting osteointegration of the implants, and, at the same time, reducing reaction attributable to inflammatory processes which derive from infections which may develop in the neighborhood of the implants. In particular, the present invention relates to an endo-osseous implant comprised of biocompatible metallic materials; characterized in that said implant comprises a coating comprised of nanocrystalline material comprising nanoparticles of formula (I) AO10-29-2009

Francesco Carinci, Bologna IT

Patent application numberDescriptionPublished
20080254201Method for Preparing Endosseous Implants with Zircon Dioxide Coating - The method includes the following steps: formulation of liquid, non-gelled and stable precursors by solvolysis of ZV (IV) compounds; precursor deposition on endosseous implant surface; thermal treatment to achieve film densification, in the presence of oxygen, of a complex formed by the said endosseous implant and precursor, to obtain on the implant surface a thin nanocrystalline zirconium dioxide film.10-16-2008
20090005880Method for Preparing Endosseous Implants Anatase Titanium Dioxide Coating - The method includes the following steps: formulation of liquid, non-gelled and stable precursor by solvolysis of Ti(IV) compounds; precursor deposition on endosseous implant surface; thermal treatment to achieve film densification, in the presence of oxygen, of a complex formed by the above mentioned endosseous implant and precursor, to obtain on the implant surface a thin film of nanocrystalline titanium dioxide with good mechanical and chemical stability. The complex above, under a persistent W irradiation modify its surface status conferring a sensible increasing of wettability chemical and biological decontamination.01-01-2009
20090035376Stem cells obtained from pulp of deciduous or permanent teeth and of dental germ, able to produce human bone tissue - In this invention is described a method that foresees the isolation of a new subpopulation of stem cells derived form dental pulp, whose differentiation is osteoblasts lead to the subsequent production and employment of a bone tissue, called LAB (Living Autologous Bone). Specifically, the invention describes: 1) the isolation of stem cells from the pulp of deciduous and permanent teeth and of dental germs, obtained from human subjects; 2) the growth of these cells in vitro, under specific conditions that allow the isolation of a cellular sub-population, which, after differentiation in osteoblasts, is able to produce in vitro an extracellular matrix, identical to that detectable in bone tissue; 3) the use of this selected and differentiated cell population in order to produce autologous bone tissue in vitro, containing vital osteoblasts; 4) the preservation of the LAB under conditions which guarantee cellular vitality; 5) the use of the LAB in donor patients to reconstruct bone tissue, as required in the daily practice in dentistry, maxillo-facial surgery and orthopedics.02-05-2009

Valeria Carinci, Siena IT

Patent application numberDescriptionPublished
20080248059Dimensional Analysis of Saccharide Conjugates with Gpc & Sec-Mals - GPC (gel permeation chromatography) and size exclusion chromatography with detection by multi-angle light scattering photometry (SEC-MALS) can be used to accurately measure molecular size and molar mass, respectively, of saccharide conjugates. The invention provides (a) a process for measuring the molecular size of a conjugated saccharide antigen within a sample, comprising a step of analyzing the sample by GPC, and (b) a process for measuring the molar mass of a conjugated saccharide antigen within a sample, comprising a step of analysing the sample by SEC-MALS.10-09-2008