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Carboni
Joan Carboni, Yardley, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090299040 | MULTIVALENT FIBRONECTIN BASED SCAFFOLD DOMAIN PROTEINS - The present invention relates to multivalent polypeptides comprising at least two fibronectin scaffold domains connected via a polypeptide linker. The invention also relates to multivalent polypeptides for use in diagnostic, research and therapeutic applications. The invention further relates to cells comprising such proteins, polynucleotide encoding such proteins or fragments thereof, and to vectors comprising the polynucleotides encoding the innovative proteins. | 12-03-2009 |
| 20100179094 | BISPECIFIC EGFR/IGFIR BINDING MOLECULES - The present invention relates to bispecific molecules comprising an EGFR binding domain and a distinct IGFIR binding domain for use in diagnostic, research and therapeutic applications. The invention further relates to cells comprising such proteins, polynucleotide encoding such proteins or fragments thereof, and vectors comprising the polynucleotides encoding the innovative proteins. Exemplary bispecific molecules include antibody-like protein dimers based on the tenth fibronectin type III domain. | 07-15-2010 |
Joan M. Carboni, Yardley, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20100184125 | BIOMARKERS AND METHODS FOR DETERMINING SENSITIVITY TO INSULIN GROWTH FACTOR-1 RECEPTOR MODULATORS - IGF1R biomarkers useful in a method for identifying and monitoring a mammal that will respond therapeutically to a method of treating cancer comprising administering an IGF1R modulator, wherein the method comprises (a) exposing the mammal to the IGF1R modulator and (b) measuring in the mammal the level of the at least one biomarker, wherein a difference in the level of the at least one biomarker measured in (b) compared to the level of the biomarker in a mammal that has not been exposed to the IGF1R modulator indicates that the mammal will respond therapeutically to the method of treating cancer and (c) wherein the level of the biomarker in a mammal after exposure to a IGF1R modulator indicates that the mammal has responded therapeutically to the method of treating cancer. | 07-22-2010 |
| 20110123545 | COMBINATION OF VEGFR2 AND IGF1R INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISEASES - Methods for increasing endothelial cell apoptosis under hypoxic conditions in a patient undergoing a treatment that comprises an IGF1R inhibitor, the method comprising administering to the patient a VEGFR2 inhibitor | 05-26-2011 |
Lorenzo Carboni, Beinette (cuneo) IT
| Patent application number | Description | Published |
|---|---|---|
| 20110146217 | STALK-CHOPPER AND MACHINE FOR HARVESTING MAIZE EQUIPPED WITH SUCH STALK-CHOPPER - A stalk-chopper, in particular for a machine for harvesting maize, comprising a hollow casing having a central portion and two box-section arms that extend in cantilever fashion from the central portion according to a U-shaped configuration, the box-section arms being set at a distance from one another in a transverse direction and having respective distal ends set at a distance from the central portion in a longitudinal direction, two rotating output members projecting on the outside of said box-section arms at the respective distal ends of said box-section arms, the output members being carried in a rotatable way by the respective arms about respective mutually parallel axes of rotation, two rotary cutting devices connected to respective output members and having respective cutting diameters partially overlapping one another; and a transmission device housed within said hollow casing and provided for driving said output members in rotation in concordant directions. | 06-23-2011 |
| 20110146218 | MACHINE FOR HARVESTING MAIZE - A machine for harvesting maize, comprising a supporting structure carrying a plurality of harvesting units set alongside one another in a transverse direction, wherein each harvesting unit comprises, a framework fixed with respect to the supporting structure and including two box sections set at a distance from one another in a transverse direction by an empty space elongated in a longitudinal direction, two stripper plates carried by respective box sections, the stripper plate having respective edges facing one another that extend on opposite sides in said empty space, the facing edges of said stripper plates forming a squeezing channel, and a pair of counter-rotating traction rollers arranged underneath said squeezing channel, wherein said stripper plates are mobile in a vertical direction with respect to the respective box sections between a raised position and a lowered position and are associated to respective spring devices that push the stripper plates elastically towards said raised position. | 06-23-2011 |
Salvatore Carboni, Bologna IT
| Patent application number | Description | Published |
|---|---|---|
| 20090193758 | Machine for packaging products in wrappers of sheet material - In a packaging machine, typically a cellophaner for overwrapping packets of cigarettes, each of the packets is enveloped by a wrapping unit in a heat shrinkable wrapper presenting at least two opposite faces disposed parallel one with another. The machine also comprises a unit by which heat is applied to the wrappers, equipped with a pair of belt conveyors that present two branches, facing one another and set in motion in such a way as to transport the packets by gripping the two opposite faces of each wrapper, and at least one heating head associated with each transport branch; the heating heads are faced with a leaf of lamellar graphite bonded to the head on one side and offered in direct contact on the other to the respective branch of the corresponding belt conveyor, so as to minimize friction between the belt and the head. | 08-06-2009 |
| 20090260640 | Unit and a method for wrapping tobacco products - Tobacco products are wrapped by a unit equipped with a rotating drum carrying a set of holder mechanisms around the periphery, each rotatable about an axis parallel to the axis of the drum, by which single products are supported and carried through an assembly station together with leaves of wrapping material received from a vacuum roller turning on an axis parallel to the axis of the drum; the vacuum roller revolves tangentially to the drum at the assembly station and comprises a system by which each leaf is transferred to a gripper associated with the support mechanism. The transfer system is timed to operate in a situation of substantially zero relative peripheral velocity between the support mechanism and the vacuum roller. | 10-22-2009 |
Vittorio Carboni, Genova IT
| Patent application number | Description | Published |
|---|---|---|
| 20090137158 | CONNECTION DEVICE FOR ELECTRICAL OR ELECTRONIC CONNECTIONS - Connection device for electrical or electronic connections, comprising a socket connector ( | 05-28-2009 |
| 20090203268 | CONTACT FOR ELECTRICAL AND ELECTRONIC CONNECTIONS - Contact for electrical or electronic connections, comprising a contact pin ( | 08-13-2009 |