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Cao, PA

Han Cao, Philadelphia, PA US

Patent application numberDescriptionPublished
20080242556METHODS OF MACROMOLECULAR ANALYSIS USING NANOCHANNEL ARRAYS - Methods of analyzing features such as the physical size of macromolecules or biomarkers along large genomic DNA molecules were disclosed as well as the devices for carrying out such high throughput analysis in a massively parallel fashion. Methods of fabricating such devices are also disclosed.10-02-2008
20090305273NANONOZZLE DEVICE ARRAYS: THEIR PREPARATION AND USE FOR MACROMOLECULAR ANALYSIS - Constricted nanochannel devices suitable for use in analysis of macromolecular structure, including DNA sequencing, are disclosed. Also disclosed are methods for fabricating such devices and for analyzing macro-molecules using such devices.12-10-2009
20100029508NANOCHANNEL ARRAYS AND THEIR PREPARATION AND USE FOR HIGH THROUGHPUT MACROMOLECULAR ANALYSIS - Nanochannel arrays that enable high-throughput macromolecular analysis are disclosed. Also disclosed are methods of preparing nanochannel arrays and nanofluidic chips. Methods of analyzing macromolecules, such as entire strands of genomic DNA, are also disclosed, as well as systems for carrying out these methods.02-04-2010
20110171634METHODS AND DEVICES FOR SINGLE-MOLECULE WHOLE GENOME ANALYSIS - Provided are methods and devices for single-molecule genomic analysis. In one embodiment, the methods entail processing a double-stranded nucleic acid and characterizing said nucleic acid. These methods are useful in, e.g., determining structural variations and copy number variations between individuals.07-14-2011

Patent applications by Han Cao, Philadelphia, PA US

Jie Cao, Upper Darby, PA US

Patent application numberDescriptionPublished
20080307536Voltage-Gated, Ph-Sensitive Anion Channel And Its Novel Splice Variant Involved In Taste Sensation - The invention provides a novel splice-variant of the ClC-4 protein, termed ClC-4A. ClC-4A is expressed in taste bud cells and is involved in sour taste perception. The invention provides ClC-4A polynucleotides and ClC-4A polypeptides, vectors, host cells and ClC-4A specific antibodies as well as designing high potency taste stimuli, determining taste preferences in animals, developing breed-specific foods, and modifying the taste of foods and medications.12-11-2008

Jin Cao, Allentown, PA US

Patent application numberDescriptionPublished
20090280444Highly Radiative Burner and Combustion Process - An oxy-fuel burner that co-fires liquid fuel and gaseous fuel to create a more luminous flame. The characteristics of a liquid fuel spray and the gaseous fuel and primary oxidant gas flows, as well as the geometry of the burner is adapted to shroud the liquid fuel from the primary oxidant until it exits a precombustor and to prevent the liquid fuel from contacting the walls of the precombustor.11-12-2009
20110154950Burner and Method for Processing Oxidizable Materials - Burner assembly for use in industrial heating and melting applications of material susceptible to oxidation at elevated temperatures is comprised of a flow passage of oxidant surrounded by an annular flow passage of fuel whereby the oxidant is substantially contained inside the fuel layer up to at least 5 oxidant nozzle diameters downstream of the burner outlet in order to minimize contact between the oxidant and the furnace load.06-30-2011

Patent applications by Jin Cao, Allentown, PA US

Qinghong Cao, Allentown, PA US

Patent application numberDescriptionPublished
20100144389CORDLESS TELEPHONE WITH MP3 PLAYER CAPABILITY - A cordless telephone which allows a user to play MP3 digital audio bit stream music, a video game, either alone or with a user of another cordless telephone, using the remote handset of a cordless telephone to control the functions of the MP3 player. The cordless telephone remains usable as a typical cordless telephone with all the features and conveniences of a cordless telephone including, but not limited to, connection of a telephone call between a calling party and a called party, caller ID information, voice messaging features, etc. MP3 digital audio bit stream music may be downloaded from a remote source through, e.g., the Internet and a PC.06-10-2010
20110201384Cordless Telephone with Digital Audio Player Capability - A cordless telephone which allows a user to play MP3 digital audio bit stream music, using the remote handset of a cordless telephone to control the functions of the MP3 player. The cordless telephone remains usable as a typical cordless telephone with all the features and conveniences of a cordless telephone including, but not limited to, connection of a telephone call between a calling party and a called party, caller ID information, voice messaging features, etc. MP3 digital audio bit stream music may be downloaded from a remote source through, e.g., the Internet and a PC.08-18-2011

Patent applications by Qinghong Cao, Allentown, PA US

Tinghua Cao, Malvern, PA US

Patent application numberDescriptionPublished
20090142317PROCESS FOR REDUCING EFFECTS OF GRAFT VERSUS HOST DISEASE USING EX VIVO EXPANDED CD4+CD25+ REGULATORY T CELLS - Disclosed in this specification is a process for producing ex vivo expanded CD4+CD25+ regulatory T cells. The process includes the steps of extracting a sample that includes peripheral blood mononuclear cells from a human donor. The extracted cells include a certain number of cells which are CD4+CD25+ regulatory T cells. The relative population of the CD4+CD25+ regulatory T cells is enhanced such that the Treg cells constitute the majority of the cells in the sample. Thereafter, the population of the enriched Treg cells, that may include third-party derived Treg cells, is expanded to produce a clinically meaningful population of cells for use in the treatment of GVHD.06-04-2009
20090142320METHOD TO MINIMIZE IL-17 PRODUCTION DURING nTREG CELL EXPANSION - Disclosed in this specification is a method to promote the growth of CD4+CD25Foxp3+ nTreg cells in a culture while minimizing the production of IL-17. The resulting cells are useful in the treatment of immune-related diseases.06-04-2009
20100291117METHOD FOR EX-VIVO EXPANSION OF REGULATORY T CELLS WITH ENHANCED SUPPRESSIVE FUNCTION FOR CLINICAL APPLICATION IN IMMUNE MEDIATED DISEASES - The invention provides methods for the ex-vivo expansion of CD4+CD25+ Tregs. The invention provides a method for producing ex vivo expanded Tregs that may be used to inhibit unwanted human immune responses against self-antigens or allergens. Additionally, the ex vivo expanded Tregs may provide treatment for inflammatory/automimmune diseases.11-18-2010

Wei Cao, Orefield, PA US

Patent application numberDescriptionPublished
20110247979Process for Separating Components of a Multi-Component Feed Stream - Provided is a process and apparatus for separating a multi-component feed stream wherein a porous separator is used to effectively create, via permeation and phase change, at least three fractions of differing compositions.10-13-2011

Wenjing Cao, Philadelphia, PA US

Patent application numberDescriptionPublished
20100144634Compositions and Methods for Modulation of ADAMTS13 Activity - Compositions and methods are provided for the diagnosis and treatment of thrombotic thrombocytopenic purpura (TTP), stroke and myocardial infarction.06-10-2010