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Canepa
Barbara Canepa, San Sebastiano Da Po IT
| Patent application number | Description | Published |
|---|---|---|
| 20110052493 | USE OF POLYPEPTIDES OBTAINED THROUGH SYSTEMATIC MUTATIONS OF SINGLE AMINO ACIDS OF HUMAN AND NON-HUMAN BOX-A OF HMGB1 TO PREVENT AND/OR ANTAGONIZE PATHOLOGIES INDUCED BY HMGB1 - The present invention relates to polypeptide variants of the HMGB-1 high affinity binding domain Box-A (HMGB1 Box-A) or to a biologically active fragment of HMGB1 Box-A, which are obtained through systematic mutations of single amino acids of the wild-type HMGB1 Box-A protein and which show an increased resistance to proteases and which are therefore characterized by more favourable pharmacokinetic and pharmacodynamic profiles. Moreover, the present invention concerns the use of said polypeptide molecules of HMGB1 Box-A to diagnose, prevent, alleviate and/or treat pathologies associated with extracellular HMGB1 and associated with RAGE. | 03-03-2011 |
Giovanni Canepa, Genova IT
| Patent application number | Description | Published |
|---|---|---|
| 20100064504 | RAILWAY BEACON AND RELATED PRODUCTION METHOD - A railway beacon having a casing ( | 03-18-2010 |
Loni M. Canepa, San Diego, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100208056 | Pipe Inspection System with Replaceable Cable Storage Drum - A pipe inspection system includes a cable storage drum and a housing configured to removably receive and rotatably support the cable storage drum. A push-cable with a plurality of conductors is stored in the cable storage drum. A camera head is connected to a distal end of the push-cable. A slip-ring assembly has first and second mating portions that when mated provide conductive paths between the plurality of conductors at a proximal end of the push-capable and a display device. The first portion of the slip-ring assembly is mounted on the housing and the second portion of the slip-ring assembly is mounted on the removable cable storage drum. The system connection cable joining the inspection system with a display unit is removable and may be replaced with cables compatible with various alternate image display systems. | 08-19-2010 |
| 20100265176 | Magnetic Manual User Interface Devices - Various finger tip controlled manual interface devices that can be used as inputs to personal computers, electromechanical systems and video game consoles utilize concentrically arranged magnets. The polarities of the magnets are oriented to provide restoration forces on a one of the magnets to bias it toward a neutral position. A magnetic sensor including a plurality of sensing elements such as Hall effect devices generates output signals representative of direction and amount of movement of the magnet that is biased to the neutral position. | 10-21-2010 |