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Canales, CA

Eda Canales, San Mateo, CA US

Patent application numberDescriptionPublished
20110020278INHIBITORS OF FLAVIVIRIDAE VIRUSES - Provided are compounds of Formula I:01-27-2011
201101234932,4,6-TRISUBSTITUTED PYRIDO(3,2-d) PYRIMIDINES USEFUL FOR TREATING VIRAL INFECTIONS - Pyrido(3,2-d)pyrimidine derivatives represented by the structural formula (Ia): wherein, R05-26-2011

Eda Canales, Foster City, CA US

Patent application numberDescriptionPublished
20100310512ANTIVIRAL COMPOUNDS - The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.12-09-2010

Miguel G. Canales, Los Altos, CA US

Patent application numberDescriptionPublished
20080234602BIOLOGICAL UNIT REMOVAL TOOLS WITH RETENTION MECHANISM - Tools and methods are provided for removing biological units from a body surface utilizing a removal tool. The tools may incorporate retention members and mechanisms configured to impede movement of the biological unit in the direction of a distal end of the tool and to improve retention of the biological unit in the tool. Some of the retention members are stationary and some are movable within the lumen of the biological unit removal tools. The distal tips of the tools are desirably configured to reduce the chance of transection of a biological unit, such as by including both cutting segments and blunt relief segments. A number of dual concentric tube embodiments permit a division of removal functions. Distal fluid or gas delivery may supplement a vacuum in a luminal space to help extract biological units from surrounding tissue.09-25-2008
20080234698HARVESTING TOOLS FOR BIOLOGICAL UNITS - Tools and methods are provided for removing biological units from a body surface utilizing a removal tool. The tools may incorporate retention members and mechanisms configured to impede movement of the biological unit in the direction of a distal end of the tool and to improve retention of the biological unit in the tool. Some of the retention members are stationary and some are movable within the lumen of the biological unit removal tools. The distal tips of the tools are desirably configured to reduce the chance of transection of a biological unit, such as by including both cutting segments and blunt relief segments. A number of dual concentric tube embodiments permit a division of removal functions. Distal fluid or gas delivery may supplement a vacuum in a luminal space to help extract biological units from surrounding tissue.09-25-2008
20080234699BIOLOGICAL UNIT REMOVAL TOOLS WITH CONCENTRIC TUBES - Tools and methods are provided for removing biological units from a body surface utilizing a removal tool. The tools may incorporate retention members and mechanisms configured to impede movement of the biological unit in the direction of a distal end of the tool and to improve retention of the biological unit in the tool. Some of the retention members are stationary and some are movable within the lumen of the biological unit removal tools. The distal tips of the tools are desirably configured to reduce the chance of transection of a biological unit, such as by including both cutting segments and blunt relief segments. A number of dual concentric tube embodiments permit a division of removal functions. Distal fluid or gas delivery may supplement a vacuum in a luminal space to help extract biological units from surrounding tissue.09-25-2008
20090005765FOLLICULAR UNIT HARVESTING TOOLS INCLUDING DEVICES AND THEIR USE FOR SEVERING CONNECTIVE TISSUE - Devices and methods are disclosed which provide for harvesting hair follicular units, including severing any remaining connective tissue strands during the harvesting process, so that the harvested follicular units are retained in the harvesting tool without being damaged. The devices and methods of the present invention are especially useful with the partially or substantially automated systems and methods for hair harvesting and transplantation. The follicular unit harvesting tools may comprise a harvesting cannula and a grasping device moveable relative to each other.01-01-2009
20100234871SYSTEM AND METHOD FOR HARVESTING AND IMPLANTING HAIR USING IMAGE-GENERATED TOPOLOGICAL SKIN MODELS - Systems and methods are provided for orienting a hair harvesting tool relative to a follicular unit to be harvested. Further, systems and methods of implanting follicular units are provided, which are based on the orientation of the existing follicular units or based on pre-determined insertion angle. The provided systems and methods use image processing and image-generated topological skill models. In some embodiments surface fit is performed using, for example, a planar fit, quadric fit, cubic fit, mesh fit and parametric fit.09-16-2010
20110060321FOLLICULAR UNIT HARVESTING TOOL - The invention provides a device and a method for improving hair harvesting and extraction. The device includes a mechanism for assisting in separation of the hair graft from the surrounding connective tissue. The apparatus and methods of the current invention are such that the viability of the follicular unit contained within the extracted plug is substantially preserved.03-10-2011

Patent applications by Miguel G. Canales, Los Altos, CA US

Roger Canales, Redwood City, CA US

Patent application numberDescriptionPublished
20090138981Biotic and abiotic stress tolerance in plants - Transcription factor polynucleotides and polypeptides incorporated into nucleic acid constructs, including expression vectors, have been introduced into plants and were ectopically expressed. Transgenic plants transformed with many of these constructs have been shown to be more resistant to disease (in some cases, to more than one pathogen), or more tolerant to an abiotic stress (in some cases, to more than one abiotic stress). The abiotic stress may include, for example, salt, hyperosmotic stress, water deficit, heat, cold, drought, or low nutrient conditions.05-28-2009
20110126326STRONG ACTIVATION DOMAIN - A new and strong transcriptional activation domain was identified from the 05-26-2011

Roger D. Canales, Redwood City, CA US

Patent application numberDescriptionPublished
20100175145PLANT TRANSCRIPTIONAL REGULATORS - The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having improved tolerance to drought, shade, and low nitrogen conditions, as compared to wild-type or reference plants.07-08-2010