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Callewaert

Clyde Maynord Callewaert, Shelby Township, MI US

Patent application numberDescriptionPublished
20090051463SPLITTER/COMBINER CIRCUIT - A circuit for combining/splitting at least two RF signals comprising: (a) at least two or more transmission portions coupled at an intersection, the intersection having a common port for inputting or outputting a combination of the at least two RF signals; (b) each transmission portion extending from the intersection to a port for inputting or outputting a selection of signals from the combination, and comprising at least one set of intersecting transmission lines; (c) each set of intersecting transmission lines rejecting a particular signal of the combination; and (d) each intersecting transmission line of a given set having a length of about an odd multiple of a quarter wavelength of the particular signal which is rejected by the given set.02-26-2009

Clyde Maynord Callewaert, Shelby Twp, MI US

Patent application numberDescriptionPublished
20100171566SPLITTER/COMBINER CIRCUIT - A circuit for combining/splitting first and second RF signals having different wavelengths of x and y, respectively, the circuit comprising: (a) first and second transmission portions coupled at an intersection, the first transmission portion comprising at least two intersecting transmission lines, each having a length which is an odd multiple of about ¼y, the second transmission portion comprising at least two intersecting transmission lines, each having a length which is an odd multiple of about ¼x; and (b) first, second and third ports, the first port located at the first transmission portion, the second port located at the intersection of the first and second transmission portions, and the third port being located at the second transmission portion, the first and second ports being electrically coupled, and the second and third ports being electrically coupled.07-08-2010

Danilo Frantz Callewaert, Wevelgem BE

Patent application numberDescriptionPublished
20110123657METHOD FOR OBTAINING HIGHLY PURIFIED AND INTACT SOYBEAN HYPOCOTYLS - The present invention relates to a method for processing soybean (or soya) material, which is mainly a mixture of soybean hypocotyls and soybean cracks. In particular, the present invention provides a method for separating a soybean hypocotyl fraction from a soybean crack fraction based on a difference in form, by subjecting said soybean material to a centrifugal force, preferably by use of an indented cylindrical device. On beforehand, it is preferable to remove the main part of the soybean hulls, soybean cotyledons, whole soybeans, and the larger soybean crack fraction from the soybean material by means of traditional separation methods based on differences in size and/or weight (e.g. aspiration). The invention also provides a soybean hypocotyl concentrate and uses thereof, e.g. for the preparation of a soybean hypocotyl (or germ or embryo) oil and/or food products.05-26-2011

Denis M. Callewaert, Metamora, MI US

Patent application numberDescriptionPublished
20110117122COMPOSITION AND METHOD FOR AFFECTING CYTOKINES AND NF-kB - The present invention discloses a composition and method for effecting various cytokines and NF-κB by administering an effective amount of a phyto-percolate composition to an individual. In various exemplary embodiments, the composition is claimed to be useful for the effective treatment of inflammation, cancer, and/or various infections including HIV by regulation of various interleukins, such as IL-10 and IL-2, and of transcription factors including NF-κB.05-19-2011

Nico Callewaert, Nevele BE

Patent application numberDescriptionPublished
20120128720MYCOBACTERIUM MUTANTS FOR VACCINES WITH IMPROVED PROTECTIVE EFFICACY - Tuberculosis (TB) is a major health problem and currently, the only licensed TB vaccine is 05-24-2012

Nico Callewaert, Nevele-Hansbeke BE

Patent application numberDescriptionPublished
20110021378NUCLEIC ACIDS OF PICHIA PASTORIS AND USE THEREOF FOR RECOMBINANT PRODUCTION OF PROTEINS - The present invention provides the genome sequence of 01-27-2011
20110092374METHODS FOR PRODUCING SUBSTANTIALLY HOMOGENEOUS HYBRID OR COMPLEX N-GLYCANS IN METHYLOTROPHIC YEASTS - The present invention provides methods for effectively and efficiently converting methylotrophic yeast's heterogeneous high mannose-type N-glycosylation to mammalian-type N-glycosylation by disruption of an endogenous glycosyltransferase gene (OCH1) and step-wise introduction of heterologous glycosidase and glycosyltransferase activities. Each engineering step includes a number of stages: transformation with an appropriate vector, cultivation of a number of transformants, performance of sugar analysis and heterologous protein expression analysis, and selection of a desirable clone. The selected clone is then subjected to the next engineering step.04-21-2011
20120029174METHODS FOR PRODUCING SUBSTANTIALLY HOMOGENEOUS HYBRID OR COMPLEX N-GLYCANS IN METHYLOTROPHIC YEASTS - The present invention provides methods for effectively and efficiently converting methylotrophic yeast's heterogeneous high mannose-type N-glycosylation to mammalian-type N-glycosylation by disruption of an endogenous glycosyltransferase gene (OCH1) and step-wise introduction of heterologous glycosidase and glycosyltransferase activities. Each engineering step includes a number of stages: transformation with an appropriate vector, cultivation of a number of transformants, performance of sugar analysis and heterologous protein expression analysis, and selection of a desirable clone. The selected clone is then subjected to the next engineering step.02-02-2012

Nico L.m. Callewaert, Nevele BE

Patent application numberDescriptionPublished
20110191913CELLS PRODUCING GLYCOPROTEINS HAVING ALTERED GLYCOSYLATION PATTERNS AND METHOD AND USE THEREOF - The present application relates to the field of glyco-engineering, more specifically to eukaryotic cells wherein both an endoglucosaminidase and a glycoprotein are present. These cells can be used to deglycosylate or partly deglycosylate the (exogenous) glycoprotein, in particular without the need for adding an extra enzyme. Methods are also provided for the application of these cells in protein production. According to one specific aspect, the eukaryotic cells and methods are glyco-engineered yeast cells in which additionally at least one exogenous enzyme needed for complex glycosylation is present, e.g. allowing easier separation of differentially glycosylated glycoproteins.08-04-2011

Nico L. M. Callewaert, Lichtervelde BE

Patent application numberDescriptionPublished
20090263863MODIFICATION OF PROTEIN GLYCOSYLATION IN METHYLOTROPHIC YEAST - The present invention relates to methods and genetically engineered methylotrophic yeast strains for producing glycoproteins with mammalian-like glycosylation. The present invention also relates to vectors useful for generating methylotrophic yeast strains capable of producing glycoproteins with mammalian-like glycosylation. Glycoproteins produced from the genetically engineered methylotrophic yeast strains are also provided.10-22-2009
20100267084PROTEIN GLYCOSYLATION MODIFICATION IN METHYLOTROPHIC YEAST - The present invention provides genetically engineered strains of 10-21-2010

Patent applications by Nico L. M. Callewaert, Lichtervelde BE

Nico Luc Marc Callewaert, Hansbeke-Nevele BE

Patent application numberDescriptionPublished
20090069232GLYCOSYLATION OF MOLECULES - Described herein are methods and genetically engineered cells useful for producing an altered N-glycosylation form of a target molecule. Also described are methods and molecules with altered N-glycosylation useful for treating a variety of disorders such as metabolic disorders.03-12-2009
20110201540Glycosylation of Molecules - Described herein are methods and genetically engineered cells useful for producing an altered N-glycosylation form of a target molecule. Also described are methods and molecules with altered N-glycosylation useful for treating a variety of disorders such as metabolic disorders.08-18-2011
20110207676Glycosylation of Molecules - Described herein are methods and genetically engineered cells useful for producing an altered N-glycosylation form of a target molecule. Also described are methods and molecules with altered N-glycosylation useful for treating a variety of disorders such as metabolic disorders.08-25-2011