Inventors list |
Assignees list |
Classification tree browser |
Top 100 Inventors |
Top 100 Assignees |
Caldwell, NC
Christopher T. Caldwell, Lenoir, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20090294311 | GARMENT PACKAGE - There is disclosed a garment package and method of making a garment package. A band keeps a garment in a folded condition in spite of handling by manufacturing and retailing personnel and potential customers. | 12-03-2009 |
Jason Caldwell, Durham, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20090176229 | Methods and compositions for the identification of insect repellent compounds - Methods for identifying a candidate compound with an ability to modulate cation transport through a transient receptor potential (TRP) channel in a cell are disclosed. The methods can include (a) providing a cell expressing a recombinant nucleic acid sequence encoding an transient receptor potential (TRP) channel gene product or a functional fragment or derivative thereof; (b) contacting the cell with the candidate compound; (c) comparing cation transport in the cell in the absence of the candidate compound with cation transport in the cell in the presence of the candidate compound; and (d) identifying a candidate compound through the comparing step that modulates cation transport in the cell through the transient receptor potential (TRP) channel. Also disclosed are nucleic acid and amino acid sequences for insect TRP channel gene products, antibodies that bind to the disclosed TRP channels, and recombinant host cells the include the disclosed biosequences. | 07-09-2009 |
Jennifer Caldwell, Durham, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20090263801 | Phenotype-Genotype Relationship in Age-Related Macular Degeneration - Age-Related Macular Degeneration (AMD) cases possessing the LOC387715 (rs10490924) variant have a higher risk of neovascular AMD. Individuals with AMD who are homozygous for both variants might be at greater risk for earlier onset of neovascular AMD. Determining the presence of this variant indicates which path the disease may take and which nutritional, supplement, or medicaments are appropriate. | 10-22-2009 |
Jennifer Vaughn Caldwell, Durham, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20100145223 | Peripheral Reticular Pigmentary Change and Age-Related Macular Degeneration - Examination of 956 age-related macular degeneration cases showed that the complement factor H variant (Y402H, C allele at rs1061170) increases risk for the development of peripheral reticular pigmentary change. AMD phenotypes of 796 carriers of the CFH Y402H variant were compared to the AMD phenotypes of 160 non-carriers. Of 34 phenotypic features analyzed, only peripheral reticular pigmentary change (PRPC) was associated with this CFH variant (P-value 0.0006). The proportion of AMD cases with PRPC correlated with the number of CFH risk C alleles in a dose-response fashion. The association of CFH Y402H polymorphism with PRPC suggests that AMD changes are not limited to the macula. Current AMD grading methods assess only the macula; peripheral retinal changes should also be included in grading methods. PRPC may be used as a surrogate of a high-risk genotype and may be used for diagnostic, therapeutic, and research purposes. | 06-10-2010 |
Richard Caldwell, Durham, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20100160398 | Farnesoid X Receptor Agonists - The present invention provides novel substituted isoxazole compounds, pharmaceutical compositions, therapeutic uses and processes for preparing the same. | 06-24-2010 |
Richard Dana Caldwell, Durham, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20090093464 | Naphthalene Derivatives as Modulators of the Glucocorticoid Receptor - The present invention relates to naphthalene derivatives of formula (I) that are modulators of the glucocorticoid receptor, and to processes for the preparation and use of the same. | 04-09-2009 |
| 20100261772 | Cycloalkylidene Compounds As Selective Estrogen Receptor Modulators - The present invention relates to compounds of formula (I) with a variety of therapeutic uses, more particularly the substituted cyclic alkylidene compounds are useful for selective estrogen receptor modulation. | 10-14-2010 |
Steven R. Caldwell, Cary, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20100026604 | METHODS OF MODIFYING ERECT CONCEALED ANTENNA TOWERS AND ASSOCIATED MODIFIED TOWERS AND DEVICES THEREFOR - The disclosure describes installing an antenna canister in a portion of a concealed antenna pole at a location that is below a top of the pole while the antenna pole is erect and associated components to facilitate the procedure, as well as multi-piece vertical rods, pole mounting bracket assemblies and retrofit kits. | 02-04-2010 |
| 20110156984 | METHODS OF MODIFYING ERECT CONCEALED ANTENNA TOWERS AND ASSOCIATED MODIFIED TOWERS AND DEVICES THEREFOR - The disclosure describes installing an antenna canister in a portion of a concealed antenna pole at a location that is below a top of the pole while the antenna pole is erect and associated components to facilitate the procedure, as well as multi-piece vertical rods, pole mounting bracket assemblies and retrofit kits. | 06-30-2011 |
William Eric Caldwell, Taylorsville, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20090034918 | Fiber optic cables having coupling and methods therefor - A fiber optic cable including at least one optical fiber disposed within a cavity of a cable jacket and methods for manufacturing the same are disclosed. The cavity has a first cavity cross-sectional area and a second cavity cross-sectional area located at different longitudinal locations along the cable, where the first cavity cross-sectional area is greater than the second cavity cross-sectional area. The region of the second cavity cross-sectional area of the cable provides and/or increases the coupling level of the at least one optical fiber to the cable jacket. In further embodiments, the fiber optic cable is a dry cable having one or more dry insert within the cavity for cushioning and/or optionally providing water-blocking for the cable. | 02-05-2009 |
| 20090274425 | Fiber Optic Cables Having Coupling and Methods Therefor - A fiber optic cable including at least one optical fiber disposed within a cavity of a cable jacket and methods for manufacturing the same are disclosed. The cavity has a first cavity cross-sectional area and a second cavity cross-sectional area located at different longitudinal locations along the cable, where the first cavity cross-sectional area is greater than the second cavity cross-sectional area. The region of the second cavity cross-sectional area of the cable provides and/or increases the coupling level of the at least one optical fiber to the cable jacket. In further embodiments, the fiber optic cable is a dry cable having one or more dry insert within the cavity for cushioning and/or optionally providing water-blocking for the cable. | 11-05-2009 |
William Eric Caldwell, Hickory, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20090034919 | Fiber optic cables using dry inserts for coupling and methods therefor - A fiber optic cable including at least one optical fiber and at least one dry insert disposed within a cavity of a cable jacket and methods for manufacturing the same are disclosed. The dry insert has a first thickness and a second thickness located at different longitudinal locations along the dry insert, where the first thickness is greater than the second thickness. The region of the cable having the first thickness of the dry insert provides and/or increases the coupling level of the at least one optical fiber to the cable jacket. In further embodiments, the optical fiber(s) have a predetermined level of coupling to the cable jacket that is about 0.1625 Newtons or more per optical fiber for a thirty meter length of fiber optic cable. | 02-05-2009 |
William S. Caldwell, Winston Salem, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20100121061 | COMPOUNDS CAPABLE OF ACTIVATING CHOLINERGIC RECEPTORS - The present invention generally relates to nicotinic compounds, in the form of aryl substituted olefinic compounds, as well as pro-drug, N-oxide, metabolite and pharmaceutically acceptable salt forms thereof. Methods of modulating neurotransmitter release via administration of the compounds, pro-drugs, N-oxides and/or pharmaceutically acceptable salts are also disclosed. | 05-13-2010 |
William Scott Caldwell, Winston-Salem, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20080214628 | Compounds Capable of Activating Cholinergic Receptors - Compounds incorporating aryl substituted olefinic amine are provided. Representative compounds are (4E)-N-methyl-5-(3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-pyrimidinyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-methoxy-3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(6-amino-5-methyl-3-pyridyl)-4-penten-2-amine, (2R)-(4E)-N-methyl-5-(3-pyridyl)-4-penten-2-amine, (2R)-(4E)-N-methyl-5-(5-isopropoxy-3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-bromo-3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-ethoxy-3-pyridyl)-4-penten-2-amine, (2S)-(4E)-N-methyl-5-(3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-isopropoxy-3-pyridyl)-4-penten-2-amine and (2S)-(4E)-N-methyl-5-(5-isopropoxy-3-pyridyl)-4-penten-2-amine. | 09-04-2008 |
| 20100160390 | COMPOUNDS CAPABLE OF ACTIVATING CHOLINERGIC RECEPTORS - Compounds incorporating aryl substituted olefinic amine are provided. Representative compounds are (4E)-N-methyl-5-(3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-pyrimidinyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-methoxy-3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(6-amino-5-methyl-3-pyridyl)-4-penten-2-amine, (2R)-(4E)-N-methyl-5-(3-pyridyl)-4-penten-2-amine, (2R)-(4E)-N-methyl-5-(5-isopropoxy-3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-bromo-3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-ethoxy-3-pyridyl)-4-penten-2-amine, (2S)-(4E)-N-methyl-5-(3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-isopropoxy-3-pyridyl)-4-penten-2-amine and (2S)-(4E)-N-methyl-5-(5-isopropoxy-3-pyridyl)-4-penten-2-amine. | 06-24-2010 |
| 20100204481 | COMPOUNDS CAPABLE OF ACTIVATING CHOLINERGIC RECEPTORS - Compounds incorporating aryl substituted olefinic amine are provided. Representative compounds are (4E)-N-methyl-5-(3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-pyrimidinyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-methoxy-3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(6-amino-5-methyl-3-pyridyl)-4-penten-2-amine, (2R)-(4E)-N-methyl-5-(3-pyridyl)-4-penten-2-amine, (2R)-(4E)-N-methyl-5-(5-isopropoxy-3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-bromo-3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-ethoxy-3-pyridyl)-4-penten-2-amine, (2S)-(4E)-N-methyl-5-(3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-isopropoxy-3-pyridyl)-4-penten-2-amine and (2S)-(4E)-N-methyl-5-(5-isopropoxy-3-pyridyl)-4-penten-2-amine. | 08-12-2010 |
| 20100222395 | COMPOUNDS CAPABLE OF ACTIVATING CHOLINERGIC RECEPTORS - Compounds incorporating aryl substituted olefinic amine are provided. Representative compounds are (4E)-N-methyl-5-(3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-pyrimidinyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-methoxy-3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(6-amino-5-methyl-3-pyridyl)-4-penten-2-amine, (2R)-(4E)-N-methyl-5-(3-pyridyl)-4-penten-2-amine, (2R)-(4E)-N-methyl-5-(5-isopropoxy-3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-bromo-3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-ethoxy-3-pyridyl)-4-penten-2-amine, (2S)-(4E)-N-methyl-5-(3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-isopropoxy-3-pyridyl)-4-penten-2-amine and (2S)-(4E)-N-methyl-5-(5-isopropoxy-3-pyridyl)-4-penten-2-amine. | 09-02-2010 |