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Calabrese

Andrew Anthony Calabrese, Kent GB

Patent application numberDescriptionPublished
20100267769Substituted Bicyclocarboxyamide Compounds - This invention provides a compound of the formula10-21-2010

Andrew Antony Calabrese, Kent GB

Patent application numberDescriptionPublished
20100222365SUBSTITUTED TRIAZOLE DERIVIATIVES AS OXYTOCIN ANTAGONISTS - The present invention relates to a class of substituted triazoles of formula (I) with activity as oxytocin antagonists, uses thereof, processes for the preparation thereof and compositions containing said inhibitors. These inhibitors have utility in a variety of therapeutic areas including sexual dysfunction, particularly premature ejaculation (P.E.).09-02-2010
20110021514AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME - Compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.01-27-2011
201100925291,2,4-Triazole Derivatives and Their Use as Oxytocin Antagonists - The present invention relates to a class of substituted triazoles of formula (I) with activity as oxytocin antagonists, uses thereof, processes for the preparation thereof and compositions containing said inhibitors. These inhibitors have utility in a variety of therapeutic areas including sexual dysfunction, particularly premature ejaculation (P.E.).04-21-2011

Patent applications by Andrew Antony Calabrese, Kent GB

Andrew Antony Calabrese, Sandwich GB

Patent application numberDescriptionPublished
20090253674Substituted Triazole Derivatives As Oxytocin Antagonists - The present invention relates to substituted triazoles of formula (I), uses thereof, processes for the preparation thereof and compositions containing said compounds. These inhibitors have utility in a variety of therapeutic areas including sexual dysfunction.10-08-2009

Patent applications by Andrew Antony Calabrese, Sandwich GB

David Calabrese, Perly CH

Patent application numberDescriptionPublished
20110061117MATRIX ATTACHMENT REGIONS (MARS) FOR INCREASING TRANSCRIPTION AND USES THEREOF - Isolated and purified MAR sequences of human and non-human animal origin are disclosed as are nucleotide sequences corresponding to or based on them. In particular, MARs and MAR constructs with high transcription and/or protein production enhancing activities are disclosed and so are methods for identifying such MARs, designing such MAR constructs and employing them, e.g., for high yield production of proteins.03-10-2011

David Calabrese, Plan-Les-Ouates CH

Patent application numberDescriptionPublished
20120231449PRODUCTS AND METHODS FOR ENHANCED TRANSGENE EXPRESSION AND PROCESSING - Disclosed are methods and eukaryotic host cells for transgene expression. The cells may be treated and/or modified to increase homologous recombination (HR), decrease non homologous end joining (NHEJ) and/or to enhance a HR/NHEJ ratio in said cell. Such cells can be transfected with vectors comprising the transgene, which advantageously integrates into the genome of the cell to form a concatemeric structure which may comprise more than 200 transgene copies. Certain expression enhancing elements such as MARs are advantageously provided to further enhance and/or facilitate transgene expression. Disclosed is also a recombinant eukaryotic host cell, in particular a non-primate host cell, comprising a transgenic sequence encoding a protein and/or a RNA, in particular a primate protein and/or RNA, involved in translocation across the ER membrane and/or secretion across the cytoplasmic membrane.09-13-2012

Davide Calabrese, Torino IT

Patent application numberDescriptionPublished
20120107034WRITING INSTRUMENT WITH RETRACTABLE TIP - A writing instrument is described, composed of a body adapted to contain therein ink or at least one ink cartridge, connected to a delivering tip for this ink, the delivering tip sliding inside the body between a first operating position in which the delivering tip goes out of an opening and a second rest position in which the delivering tip is retracted from the opening and is contained inside the body.05-03-2012

Diego Calabrese, Roma IT

Patent application numberDescriptionPublished
20120319892Acquisition of SAR images for computing a height or a digital elevation model by interferometric processing - The present invention relates to a method for acquiring SAR images for interferometric processing. The method comprises acquiring, by one or more airborne SAR sensors, SAR images of one and the same area with an acquisition geometry such that to enable interferometric processing of said SAR images. The method is characterized by an acquisition geometry in which each SAR image of the area is acquired in a respective direction of acquisition that defines a respective squint angle with respect to the direction of flight, and in which the squint angles are such that to determine a mean squint angle different from zero.12-20-2012

Giovanni Calabrese, Munich DE

Patent application numberDescriptionPublished
20110108916Semiconductor Devices and Methods - Disclosed herein are Lateral Diffused Metal Oxide Semiconductor (LDMOS) device and trench isolation related devices, methods, and techniques.05-12-2011

Nicola Calabrese, Bari IT

Patent application numberDescriptionPublished
20110111094PROCESS FOR THE PREPARATION OF VEGETABLE PRESERVES CONTAINING PROBIOTIC MICROORGANISMS - The present invention relates to a process for the preparation of vegetable preserves, comprising immersing a vegetable in a solution containing darkening inhibitors, half cooking the vegetable in water at a temperate of between 90 and 100° C., immersing the vegetable in a brine solution containing probiotic lactobacilli and/or bifidobacteria in a sterile container and sealing the container. The invention further relates to vegetable and vegetable preserves obtained by means of the process.05-12-2011

Rafael Januario Calabrese, Sao Paulo BR

Patent application numberDescriptionPublished
20090126720SUGAR CANE JUICE CLARIFICATION PROCESS - A process to clarify raw sugar cane juice, which comprises adding a source of lime, adding an anionic inorganic colloid, and separating of the resulting sugar cane juice, is disclosed.05-21-2009
20100040747SILICA MICROGELS FOR REDUCING CHILL HAZE - The present invention provides a method of reducing chill haze in a protein containing liquid (especially beverages resulting from fermentation such as beer and wine) by contacting the liquid with silica microgels having an average microgel diameter of at least 18 nm, more preferably at least 45 nm, and most preferably at least 70 nm. It has now been discovered that microgels having an average microgel diameter of less than about 18 nm do not adequately reduce chill haze of a protein containing liquid. In particular, while microgels having an average microgel diameter of less than about 18 nm cause the coagulation of haze-forming components, these components remain suspended in liquid and continue to cause haze despite allowing the liquid to settle for long periods of time. Conversely, it has now been discovered that microgels having an average microgel diameter of at least about 18 nm cause the coagulation and precipitation of haze-forming components and the rapid settling thereof without the use of an organic polymer which acts as a flocculating agent.02-18-2010
20100236492METALLIZED ANIMAL HOUSE CURTAIN - An animal house curtain comprising a metallized composite sheet can be made from a sheet layer having two outer surfaces, the sheet layer comprising at least one of a nonwoven fabric, woven fabric, nonwoven fabric-film laminate, woven fabric-film laminate, film and composites thereof, and at least one coating on at least one outer surface of the sheet layer, said coating comprising a metal coating layer having a thickness between about 15 nanometers and about 200 nanometers adjacent the outer surface of the sheet layer and wherein the emissivity of the composite sheet is less than about 0.50. Optionally, an organic coating layer of a composition containing a material selected from the group consisting of compounds, polymers, oligomers and combinations thereof, having a thickness between about 0.2 micrometer and about 2.5 micrometers can be deposited on the metal layer.09-23-2010

Patent applications by Rafael Januario Calabrese, Sao Paulo BR

Vincent Calabrese, Lausanne CH

Patent application numberDescriptionPublished
20100034055LARGE DATE CALENDAR DAY MECHANISM FOR A TIMEPIECE - The large date mechanism comprises three superposed indicator discs (02-11-2010
20100091617TIMEPIECE GEAR TRAIN - The invention concerns a timepiece gear train including at least one pair of circular toothed elements (04-15-2010
20100246338TIMEPIECE MOVEMENT INCLUDING A KARUSSEL - The timepiece movement includes a barrel, an escapement that has an escape wheel and pinion (09-30-2010
20110096635TOURBILLON AND TIMEPIECE MOVEMENT INCLUDING THE SAME - The tourbillon mechanism is characterized in that it includes a toothed wheel (04-28-2011
20110205857OSCILLATING WEIGHT FOR AN AUTOMATIC WINDING WATCH, INCLUDING A POWER RESERVE INDICATOR DEVICE INTEGRATED IN SAID OSCILLATING WEIGHT - The invention concerns an oscillating weight (08-25-2011
20120020192DUAL DISPLAY TIMEPIECE - Mechanism (01-26-2012

Patent applications by Vincent Calabrese, Lausanne CH