Patent application number | Description | Published |
20090310707 | TRANSMITTER AND METHOD FOR TRANSMITTING SOFT PILOT SYMBOLS IN A DIGITAL COMMUNICATION SYSTEM - A transmitter, channel coder, and method for coding and transmitting a sequence of symbols in a digital communication system utilizing soft pilot symbols. In one embodiment, the transmitter transmits a set of soft pilot symbols with higher reliability than the remaining symbols in the sequence by modulating the soft pilot symbols with a lower order modulation such as BPSK or QPSK while modulating the remaining symbols with a higher order modulation such as 16 QAM or 64 QAM. The transmitter shares the modulation type and location (time/frequency/code) of the soft pilot symbols with a receiver. Unlike traditional fixed pilots, the soft pilots still carry some data. Additionally, the soft pilots are particularly helpful in establishing the amplitude reference essential in demodulating the higher order modulation symbols. In another embodiment, soft pilot symbols are inserted by low-level puncturing of channel encoded bits and replacing the punctured bits with known bit patterns. | 12-17-2009 |
20090310708 | Transmitter and Method for Transmitting Soft Pilot Symbols in a Digital Communication System - A transmitter, channel coder, and method for coding and transmitting a sequence of symbols in a digital communication system utilizing soft pilot symbols. In one embodiment, the transmitter transmits a set of soft pilot symbols with higher reliability than the remaining symbols in the sequence by modulating the soft pilot symbols with a lower order modulation such as BPSK or QPSK while modulating the remaining symbols with a higher order modulation such as 16 QAM or 64 QAM. The transmitter shares the modulation type and location (time/frequency/code) of the soft pilot symbols with a receiver. Unlike traditional fixed pilots, the soft pilots still carry some data. Additionally, the soft pilots are particularly helpful in establishing the amplitude reference essential in demodulating the higher order modulation symbols. In another embodiment, soft pilot symbols are inserted by low-level puncturing of channel encoded bits and replacing the punctured bits with known bit patterns. | 12-17-2009 |
20090310715 | RECEIVER AND METHOD FOR PROCESSING RADIO SIGNALS USING SOFT PILOT SYMBOLS - A receiver and method for receiving and processing a sequence of transmitted symbols in a digital communication system utilizing soft pilot symbols. A set of soft pilot symbols are transmitted with higher reliability than the remaining symbols in the sequence by modulating the soft pilot symbols with a lower order modulation such as BPSK or QPSK while modulating the remaining symbols with a higher order modulation such as 16QAM or 64QAM. The receiver knows the modulation type and location (time/frequency/code) of the soft pilot symbols, and demodulates them first. The receiver uses the demodulated soft pilot symbols as known symbols to estimate parameters of the received radio signal. Unlike traditional fixed pilots, the soft pilots still carry some data. Additionally, the soft pilots are particularly helpful in establishing the amplitude reference essential in demodulating the higher order modulation symbols. | 12-17-2009 |
20120155574 | RECEIVER AND METHOD FOR PROCESSING RADIO SIGNALS USING SOFT PILOT SYMBOLS - A receiver and method for receiving and processing a sequence of transmitted symbols in a digital communication system utilizing soft pilot symbols. A set of soft pilot symbols are transmitted with higher reliability than the remaining symbols in the sequence by modulating the soft pilot symbols with a lower order modulation such as BPSK or QPSK while modulating the remaining symbols with a higher order modulation such as 16 QAM or 64 QAM. The receiver knows the modulation type and location (time/frequency/code) of the soft pilot symbols, and demodulates them first. The receiver uses the demodulated soft pilot symbols as known symbols to estimate parameters of the received radio signal. Unlike traditional fixed pilots, the soft pilots still carry some data. Additionally, the soft pilots are particularly helpful in establishing the amplitude reference essential in demodulating the higher order modulation symbols. | 06-21-2012 |
Patent application number | Description | Published |
20140081858 | BANKING SYSTEM CONTROLLED RESPONSIVE TO DATA READ FROM DATA BEARING RECORDS - A banking system includes a teller station and customer stations located in a bank. The teller station can communicate with each customer station. At least one customer station includes a self-service cash-dispensing automated banking machine which can carry out a financial transaction for an authorized machine user responsive to user data read from a data bearing record. The user data comprises card data and/or biometric data which correspond to a financial account. The banking system causes funds to be transferred between accounts involved in the transaction. The system allows a bank teller at the teller station to assist a bank customer at a customer station. Information can be communicated between the teller and the customer through touch input to a teller touch screen and a customer touch screen. | 03-20-2014 |
20140121830 | TIME ANALYSIS OF A BANKING SYSTEM - A banking system that utilizes metrics in acquiring and processing event data related to financial transaction activity at a plurality of automated banking machines. Automated banking machine include sensors able to detect event data during a transaction. The event data can include transaction data related to the type of transaction, time analysis data related to duration of the transaction, and operational data related to machine components used in carrying out the transaction. The event data for automated banking machines can be obtained, analyzed, and stored. Statistical averages associated with the banking system machines can be determined in real time. The averages allow a respective machine to be compared to other machines with respect to operational efficiency. An alert can be issued concerning a statistical anomaly regarding the respective machine. | 05-01-2014 |
20140253347 | TIME ANALYSIS AT A BANKING SYSTEM CONTROLLED BY DATA BEARING RECORDS - In an example embodiment, a Vehicle sensor senses the arrival and departure of vehicles in a drive-through lane. In particular embodiments, the system can calculate and store time data corresponding to each vehicle. Time data can be processed to determine the duration of transaction activity in the drive-through lane. | 09-11-2014 |
20150350185 | SYSTEM AND METHOD USING SINGLE ENTRY PASSKEY FOR PAIRING MULTIPLE PERIPHERAL DEVICES - A system for pairing a plurality of peripheral devices is disclosed, and includes a portable electronic device and a plurality of peripheral devices in wireless communication with the portable electronic device. The portable electronic device includes a processor and memory. The processor is configured to execute an instruction for prompting a user to enter a passkey only once. The processor is also configured to execute an instruction which references the memory of the portable electronic device to determine if there is at least one peripheral device that is in wireless communication with the portable electronic device that is original. The processor is configured to execute an instruction for pairing the at least one peripheral device that is original together with the portable electronic device. | 12-03-2015 |
20150350810 | SYSTEM AND METHOD FOR SIMULTANEOUS WIRELESS CONTROL OF MULTIPLE PERIPHERAL DEVICES - A system for controlling a plurality of peripheral devices includes a portable electronic device and a plurality of peripheral devices in wireless communication with the portable electronic device. The portable electronic device includes a processor configured to connect to each of the plurality of peripheral devices one at a time based on round-robin scheduling. The processor is configured to execute an instruction for searching for a broadcast signal transmitted from a selected one of the plurality of peripheral devices. The processor is configured to execute an instruction to wirelessly connect with the selected one of the plurality of peripheral devices. The processor is configured to execute an instruction to send a control signal to the selected one of the plurality of peripheral devices. The processor is configured to execute an instruction to terminate the connection between the portable electronic device and the selected one of the plurality of peripheral devices. | 12-03-2015 |
Patent application number | Description | Published |
20130183003 | Pressure-Balanced Subsea Junction Box and Cable Termination Apparatus and Method - An apparatus and method for sealably joining cables to pressure-balanced submersible junction boxes. The apparatus maintains a balanced pressure within the termination chamber; it is field installable, testable, and repairable. The termination chamber is not oil-filled; instead, it is substantially filled with a solid particulate fill material. An apparatus and method for sealably containing the cable's bitter end within the termination chamber are further provided. The apparatus includes a cable termination assembly having a chamber with a first end including a load bearing cable-attachment to sealably join a cable to the chamber, and a second end including an underwater connector. Within the chamber one or more optical and/or electrical conductors from the cable are terminated to respective one or more attachment points of the connector. The apparatus prohibits cable pistoning into the termination chamber. | 07-18-2013 |
20130216196 | OPTICAL FIBER MANAGEMENT DEVICE - An apparatus and method for managing one or more flexible lines such as optical fibers, wherein each fiber has two fixed ends. Optical fibers are arranged in a curved figure-eight pattern lying in three-dimensions and having two adjacent loops on the exterior curved winding surface of a tubular shell. The configuration is guided by winding tracks lying axially on the exterior side of shell. The curvatures of the shell and winding tracks are such that the bend of the managed fibers is everywhere equal to or greater than the fiber minimum bend radius. | 08-22-2013 |
20140270674 | PRESSURE-BALANCED SUBSEA ENCLOSURE WITH ELASTOMERIC FILL MATERIAL - A pressure-balanced enclosure for subsea use, and in particular for use as a submersible junction box in which subsea cables can be joined. The apparatus maintains a balanced pressure within the termination chamber; it is field installable, testable, and repairable. The termination chamber is not oil-filled; instead, it is substantially filled with a solid particulate fill material which includes a portion of elastomeric material. | 09-18-2014 |
Patent application number | Description | Published |
20090044003 | METHODS AND APPARATUS TO CHANGE A FEATURE SET ON DATA COLLECTION DEVICES - Methods and apparatus for modifying the feature set of data collection devices are disclosed. Requests are receiving at a computer system different from the data collection device for a new configuration of the data collection device, the request including an identifier for the data collection device, identification of one or more features, and for each identified feature, an indication to modify the operation of a feature. The identifier may comprise an identifier that is unique for a particular data collection device or an indication of a group of devices. e.g. a model number. Prior to authorizing the new configuration, a determination may be made as to whether the identified data collection device(s) are suitable for the new configuration by consulting a configuration database. To implement the new configuration, an encoded authorization file is generated based on the requested configuration and the identifier of the data collection device(s). The encoded authorization file is transmitted to one or more data collection devices. Each data collection device that receives an encoded authorization file attempts to decode of the license using its identifier(s). If the authorization file is successfully decoded, a license key on that device is updated to implement the new configuration. | 02-12-2009 |
20090088203 | Wireless bar code transaction device - A cellular camera telephone is provided with aiming, illumination, and decoding functionality to enable the economical and ergonomic reading and decoding of bar code symbols. The aiming and illumination are preferably a single system to minimize power consumption, such as by projecting a rectangle of light to both frame and illuminate the image area containing the target bar code. The cell phone is further provided with a lens system that permits switching between the ‘normal’ picture-taking focal range of from a few feet to infinity, and a bar code-reading focal range on the order of from a few to several inches. The lens system may involve, or combine, conventional autofocus/autozoom technology, fluid or adaptive lens technology, and liquid crystal lens technology. The cell phone may both acquire information from scanning bar codes, and transmit information by creating and displaying bar codes. Wireless connectivity allows the cell phone to communicate with the Internet or any of a number of network types, enabling the user to request, review, and authorize transactions. | 04-02-2009 |
20100276492 | FOCUSING APPARATUS AND TERMINAL COMPRISING VARIABLE FOCUS LENS ASSEMBLY - There is described a focusing apparatus having a deformable membrane that at least partially defines a cavity and an optical fluid disposed in the cavity. An actuator assembly can be provided for imparting a force to the deformable membrane. In one embodiment, the actuator assembly can include a piezoelectric actuator. | 11-04-2010 |
20110212751 | CELLULAR CAMERA PHONE - A cell phone includes: a device for wireless communication; an imager sensor for capturing an image of an object; a lens system for projecting an image of the object onto the imager; a battery for powering the cell phone; a lens system for focusing images of the object onto the imager comprising: a focus element; at least two electrodes associated with the focus element; a control system to adjust the state of focus of the focus element by controlling the at least two electrodes. | 09-01-2011 |
20130062409 | SCANNER WITH WAKE-UP MODE - An indicia reader system includes an indicia reader provided at a point of transaction; a controller for controlling power to the indicia reader; a detector for detecting a customer, item or shopping cart at the point of transaction and providing an indication signal to the controller of the presence of customer, item or shopping cart at the point of transaction; wherein the controller interrupts power to the indicia reader during a power save mode and resumes power to the indicia reader upon receiving the indication signal. | 03-14-2013 |
20130062413 | INDIVIDUALIZED SCANNER - A method of operating a reader system includes: providing a reader for reading information data carriers; an operator loading a configuration overlay onto the configuration settings of the reader upon successful logging, wherein the configuration overlay is specific to the operator; and reading information data carriers utilizing the configuration overlay. | 03-14-2013 |
20140070005 | SCANNER WITH WAKE-UP MODE - An indicia reader system includes an indicia reader provided at a point of transaction; a controller for controlling power to the indicia reader; a detector for detecting a customer, item or shopping cart at the point of transaction and providing an indication signal to the controller of the presence of customer, item or shopping cart at the point of transaction; wherein the controller interrupts power to the indicia reader during a power save mode and resumes power to the indicia reader upon receiving the indication signal. | 03-13-2014 |
20140217166 | METHODS AND APPARATUS TO CHANGE A FEATURE SET ON DATA COLLECTION DEVICES - Methods and apparatus for modifying the feature set of data collection devices are disclosed. Requests are receiving at a computer system different from the data collection device for a new configuration of the data collection device, the request including an identifier for the data collection device, identification of one or more features, and for each identified feature, an indication to modify the operation of a feature. The identifier may comprise an identifier that is unique for a particular data collection device or an indication of a group of devices. e.g. a model number. Prior to authorizing the new configuration, a determination may be made as to whether the identified data collection device(s) are suitable for the new configuration by consulting a configuration database. To implement the new configuration, an encoded authorization file is generated based on the requested configuration and the identifier of the data collection device(s). The encoded authorization file is transmitted to one or more data collection devices. Each data collection device that receives an encoded authorization file attempts to decode of the license using its identifier(s), if the authorization file is successfully decoded, a license key on that device is updated to implement the new configuration. | 08-07-2014 |
Patent application number | Description | Published |
20080296426 | APPARATUS AND METHOD FOR MANAGING FLEXIBLE LINES - An apparatus for managing flexible lines has first and second spool members secured together by a hinge which allows the spool members to be folded between an open condition in which the spool members are in co-planar, side-by-side positions and a folded, closed condition in which the spool members are folded towards one another until they are aligned and substantially face-to-face. Each spool member has a groove extending in an at least substantially continuous loop which receives successive windings of a line or strip as it is wound in a figure eight pattern between the two spool members in an open condition. When winding is complete, the spool members can be folded together into the folded, closed condition. | 12-04-2008 |
20090003791 | APPARATUS AND METHOD FOR MANAGING FLEXIBLE ELONGATE ELEMENTS - An apparatus for managing lengths of flexible elongate elements between two fixed points has a single spool with a track of predetermined width sufficient for winding alternate turns of the elongate element about opposite side regions of the track in a folded figure eight pattern. A first turn of the elongate element is wound about a first side region of the track, then the element is crossed over to the second side region of the track and a second turn is wound about the second side region of the track. The elongate element is crossed back over to the first side region and a third turn is wound about the first side region. The process is repeated until at least the majority of the slack between the fixed points on the element has been taken up. | 01-01-2009 |
20090080836 | WET MATE CONNECTOR - A connector has first and second connector units, each unit incorporating an oil-filled chamber housing one or more contact elements to be joined. At least one connector unit has a face seal assembly which seals the forward end of the contact chamber in the unmated condition. The face seal assembly comprises three elements. One element is an annular elastomeric seal situated radially outward. The two other elements are inner seal elements which are pressed together radially to form a substantially disc-like shape. The resulting disc-like shaped seal fills the central, circular end face opening of the outer annular seal. As the connector units are mated, elements of the elastomeric face seal assembly are displaced, one axially, and others both axially and radially, creating an opening between the oil-filled chambers that is sealed from the outside environment. | 03-26-2009 |
20110130024 | KEYLESS HARSH ENVIRONMENT CONNECTOR - A keyless harsh environment connector has a plug unit containing a pin having an outer surface carrying a plurality of axially spaced, annular contacts of gradually decreasing diameter towards a forward end of the pin, and a receptacle unit having a fluid-filled chamber containing a corresponding number of axially spaced, annular contacts of gradually increasing diameter towards a forward end of the receptacle unit, configured for mating engagement with corresponding contacts on the plug pin when the units are mated. A sealing mechanism at a forward end of the chamber seals the chamber when the units are unmated and forms a seal with the plug pin on mating of the units. The plug pin is hollow and extends through an interface between opposing seals at the front end of the receptacle contact chamber during mating. | 06-02-2011 |
20110177697 | HARSH ENVIRONMENT ROTARY JOINT ELECTRICAL CONNECTOR - A rotary joint connector has a plug having a plug contact module and a mating receptacle having a receptacle contact module designed for mating engagement with the plug contact module when the connector is fully mated. One of the units has front and rear shells which are rotatably coupled together and contain the contact module which is held in the rear shell so that the rear shell and contact module are free to rotate in the front shell. The mating contact arrangement is such that the plug and receptacle contact modules do not have to be rotationally aligned to maintain electrical contact, so that relative rotation of the electrical contacts of the two contact modules about the mating axis as a result of rotation of the rear shell does not degrade the quality of the connected circuits. | 07-21-2011 |
20110207340 | Robotically Mateable Rotary Joint Electrical Connector - A robotically mateable connector has a flying-lead plug unit and a receptacle unit adapted for releasable mating engagement with the plug unit. The plug unit includes a robotic manipulator grip assembly. A rear end shell which includes a cable attachment fitting holds a plug module having an outer surface carrying a plurality of axially spaced, annular contacts of gradually decreasing diameter towards a forward end of the module, and is rotatable relative to a plug front shell. The receptacle unit contains a receptacle module having a bore containing spaced annular contact seats of gradually increasing diameter designed for engagement with the plug contacts when the plug and receptacle units are fully mated. This provides a robotically actuated electrical connector that requires no rotational keying and relieves cable torque. | 08-25-2011 |
20120294569 | WET MATE CONNECTOR - A connector has first and second connector units, each unit incorporating an oil-filled chamber housing one or more contact elements to be joined. At least one connector unit has a face seal assembly which seals the forward end of the contact chamber in the unmated condition. The face seal assembly comprises three elements. One element is an annular elastomeric seal situated radially outward. The two other elements are inner seal elements which are pressed together radially to form a substantially disc-like shape. The resulting disc-like shaped seal fills the central, circular end face opening of the outer annular seal. As the connector units are mated, elements of the elastomeric face seal assembly are displaced, one axially, and others both axially and radially, creating an opening between the oil-filled chambers that is sealed from the outside environment. | 11-22-2012 |
20150340800 | Electrical Connector For Harsh Environments - A plug and receptacle electrical connector can be repeatedly connected and disconnected in harsh environments such as seawater. The plug unit has blade-like pins with insulated shafts and conductive tips. It engages a receptacle unit housing respective socket contacts within closed, nested, oil-filled chambers. The chambers are pressure balanced to the in-situ environment and to each other, and employ positive means to remain sealed before, during, and after mating and demating. | 11-26-2015 |
Patent application number | Description | Published |
20130057411 | METHODS AND APPARATUSES FOR SYNCHRONIZATION OF DOWNHOLE TOOL WITH REMOTE TRANSMITTERS AND SENSORS - The present disclosure includes an apparatus and method for operating a downhole tool in a borehole. The apparatus may include a downhole tool that may include at least one second clock, which may be synchronized to a first clock by way of a modulator/demodulator device. The downhole tool may be configured to estimate a parameter of interest of an underground feature. The underground feature may relate to one or more of: a borehole, a casing, or an earth formation. The downhole tool may comprise two or more sections that are configured to operate synchronously when the one or more second clocks are synchronized with the first clock. The modulator/demodulator may include a modem associated with the first clock, a modem associated with the at least one second clock, and a low frequency conductor between the two modems. The method includes using the apparatus. | 03-07-2013 |
20130153206 | APPARATUS AND METHODS FOR DETERMINING PARAMETERS DOWNHOLE USING GRAVITY-AFFECTED SENSOR - In one aspect, an apparatus for use in a wellbore is provided that in one embodiment includes a sensor having a plurality of spaced conductive contact elements, a sensing member that moves by gravity and contacts at least two contact elements in the plurality of contact elements to create an electrical short between such at least two contact elements and a circuit coupled to the contact elements configured to generate electrical signals in response to the electrical short between the contact elements. | 06-20-2013 |
20130338924 | PROCESSING AZIMUTHAL MEASUREMENT DATA - A method of processing azimuthal measurement data includes: receiving a plurality of data values generated by a rotating measurement tool, the measurement tool including at least one measurement sensor and configured to rotate and measure a signal at each of a plurality of azimuthal orientations; associating each received data value with an azimuthal orientation; selecting one or more data values that provide sufficient information regarding a measured signal, each of the selected data values having an associated azimuthal orientation; disregarding azimuthal orientations associated with one or more data values that provide insufficient information regarding a measured signal; and fitting only the selected data values to a sinusoidal curve. | 12-19-2013 |
20140000428 | Self-Lubricating Saw Blade Assembly with Debris Removal Paths | 01-02-2014 |
Patent application number | Description | Published |
20080277924 | FEMALE CONNECTOR FOR RELEASABLE COUPLING WITH A MALE CONNECTOR DEFINING A FLUID CONDUIT - The present invention is a female connector for releasable coupling with a male connector. The male connector defines a fluid conduit and includes a male end adapted to be received within the female connector. The male end includes a coupling feature. The female connector comprises an opening, a collet finger, and an actuation element. The opening is adapted to guide the male connector along a first line of action as the male connector passes into the opening to be received within the female connector. The collet finger includes an engagement feature adapted to engage the coupling feature of the male end and displace along a second line of action generally normal to the first line of action. The actuation element is adapted to displace along a third line of action generally normal to the first and second lines of action in order to disengage the engagement feature from the coupling feature of the male end. When the engagement feature is engaged with the coupling feature, the fluid conduit of the male connector is held in fluid communication with a fluid conduit of the female connector. | 11-13-2008 |
20100301599 | Latching Female Fluid Tubing Coupler - A latching female tubing coupler comprises an opening, a collet finger, and an actuation member. The opening is adapted to guide a male connector along a first line of action as the male connector passes into the opening to be received within the female connector. The collet finger includes an engagement feature adapted to engage a coupling feature of the male connector and displace along a second line of action generally normal to the first line of action. The actuation member is adapted to displace along a third line of action generally normal to the first and second lines of action in order to disengage the engagement feature from the coupling feature of the male connector. When the engagement feature is engaged with the coupling feature on a male connector, the fluid conduit of the male connector is held in fluid communication with a fluid conduit of the female connector. | 12-02-2010 |
20110204622 | Male bayonet connector - A male bayonet connector connects a section of tubing to a female latch connector. The male bayonet connector includes a shaft defining a lumen, a distal end portion, and a proximal end portion. The distal end portion of the shaft has a sealing surface configured to engage a seal member within the female latch connector to create a fluid-tight seal. The shaft defines an annular recess proximal to and adjacent the distal end portion. The annular recess has a proximal chamfered sidewall and a distal sidewall perpendicular to the axis of the lumen, which are separated by a band of smaller diameter than the sealing surface. A grip is formed on the make bayonet connector between the proximal end portion and the annular recess. A ratio of a length of the first sealing surface to a distance between the grip and the distal sidewall is such that a side-load force, as imparted on the male bayonet connector, will not break a fluid-tight seal between the sealing surface and the seal member. | 08-25-2011 |
Patent application number | Description | Published |
20090029386 | KIT FOR ENUMERATING MAMMALIAN CELL MICRONUCLEI WITH AN EMPHASIS ON DIFFERENTIALLY STAINING MICRONUCLEI AND THE CHROMATIN OF DEAD AND DYING CELLS - The present invention relates a method for the enumeration of mammalian cell micronuclei, while distinguishing micronuclei from the chromatin of dead and dying cells. The method utilizes differential staining of chromatin from dead and dying cells, to distinguish the chromatin from micronuclei and nuclei that can be detected based upon fluorescent emission and light scatter following exposure to an excitatory light source. Counting of micronuclei events relative to the number of nuclei can be used to assess the DNA-damaging potential of a chemical agent, the DNA-damaging potential of a physical agent, the effects of an agent which can modify endogenously-induced DNA damage, and the effects of an agent which can modify exogenously-induced DNA damage. Kits for practicing the invention are also disclosed. | 01-29-2009 |
20100112594 | METHOD FOR ENUMERATING MAMMALIAN CELL MICRONUCLEI WITH AN EMPHASIS ON DIFFERENTIALLY STAINING MICRONUCLEI AND THE CHROMATIN OF DEAD AND DYING CELLS - The present invention relates a method for the enumeration of mammalian cell micronuclei, while distinguishing micronuclei from the chromatin of dead and dying cells. The method utilizes differential staining of chromatin from dead and dying cells, to distinguish the chromatin from micronuclei and nuclei that can be detected based upon fluorescent emission and light scatter following exposure to an excitatory light source. Counting of micronuclei events relative to the number of nuclei can be used to assess the DNA-damaging potential of a chemical agent, the DNA-damaging potential of a physical agent, the effects of an agent which can modify endogenously-induced DNA damage, and the effects of an agent which can modify exogenously-induced DNA damage. Kits for practicing the invention are also disclosed. | 05-06-2010 |
20130337465 | METHOD FOR ENUMERATION OF MAMMALIAN CELL MICRONUCLEI, WHILE DISTINGUISHING CHROMATIN OF DEAD AND DYING CELLS - The present invention relates a method for the enumeration of mammalian cell micronuclei, while distinguishing micronuclei from the chromatin of dead and dying cells. The method utilizes differential staining of chromatin from dead and dying cells, to distinguish the chromatin from micronuclei and nuclei that can be detected based upon fluorescent emission and light scatter following exposure to an excitatory light source. Counting of micronuclei events relative to the number of nuclei can be used to assess the DNA-damaging potential of a chemical agent, the DNA-damaging potential of a physical agent, the effects of an agent which can modify endogenously-induced DNA damage, and the effects of an agent which can modify exogenously-induced DNA damage. Kits for practicing the invention are also disclosed. | 12-19-2013 |