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Cai, PA

Ann Cai, West Chester, PA US

Patent application numberDescriptionPublished
20090232734ANTI-TISSUE FACTOR ANTIBODIES AND COMPOSITIONS - Isolated anti-tissue factor antibodies, immunoglobulins, cleavage products and other specified portions and variants thereof having enhanced ADCC activity, as well as anti-tissue factor antibody compositions, encoding or complementary nucleic acids, vectors, host cells, compositions, formulations, devices, transgenic animals, transgenic plants, and methods of making and using thereof. The antibodies of the invention bind human tissue factor and demonstrate enhanced ADCC activity. Accordingly, the antibodies can be used in a variety of methods for diagnosing, treating, and/or preventing diseases involving tissue factor, where enhanced ADCC activity is desirable such as cancer.09-17-2009

Chaozhong Cai, North Wales, PA US

Patent application numberDescriptionPublished
20090318498PIPERIDYL ACRYLAMIDE ANTAGONISTS OF CCR2 - The present invention comprises compounds of Formula I.12-24-2009
20100036132PROCESS FOR THE PREPARATION OF OPIOD MODULATORS - The present invention is directed to novel processes for the preparation of opioid modulators (agonists and antagonists) and intermediates in their synthesis. The opioid modulators are useful for the treatment and prevention of as pain and gastrointestinal disorders.02-11-2010
20100152460PROCESS FOR THE PREPARATION OF OPIOID MODULATORS - The present invention is directed to novel processes for the preparation of opioid modulators (agonists and antagonists) and intermediates in their synthesis. The opioid modulators are useful for the treatment and prevention of as pain and gastrointestinal disorders.06-17-2010
201002676884-AZETIDINYL-1-HETEROARYL-CYCLOHEXANE ANTAGONISTS OF CCR2 - The present invention comprises compounds of Formula (I).10-21-2010
20110105520PYRIMIDINE COMPOUNDS AS DELTA OPIOID RECEPTOR MODULATORS - Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula I as follows:05-05-2011
20110269759PYRIMIDINE COMPOUNDS AS DELTA OPIOID RECEPTOR MODULATORS - Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula I as follows:11-03-2011

Patent applications by Chaozhong Cai, North Wales, PA US

Chaozhong Cai, N. Wales, PA US

Patent application numberDescriptionPublished
20100324051NOVEL COMPOUNDS AS OPIOID RECEPTOR MODULATORS - The present invention is directed to novel opioid receptor modulators of Formula (I).12-23-2010

Heng Cai, Yardley, PA US

Patent application numberDescriptionPublished
20120077146ORAL CARE INSTRUMENT INCLUDING AN ORAL CARE AGENT - An oral care instrument includes at least one oral care agent. In one embodiment, the oral care agent can be provided on one or more surfaces of the oral care instrument or included within cavities within the head or in one or more surfaces of a head. In other embodiment, the oral care agent can be provided in or on a thin slab subsequently bonded onto a surface, or applied as a stable coating. The oral care instrument can also be provided with a wear indicator. The oral care agents can be released during one use, during multiple uses, or throughout the life of the instrument. Water, oral secretions and/or chemicals within the mouth can activate the oral care agents.03-29-2012

Kejia Cai, Elkins Park, PA US

Patent application numberDescriptionPublished
20120019245CEST MRI METHODS FOR IMAGING OF METABOLITES AND THE USE OF SAME AS BIOMARKERS - The CEST effect for various neurotransmitters and energy metabolites in the brain and muscles and various endogenous metabolites in the liver, brain, and myocardium are imaged using MR imaging to illustrate a unique CEST effect that may be used to monitor the concentration of the metabolite and hence to characterize and monitor various disease states in the body correlated to the concentration of that metabolite. By adjusting the timing, amplitude, and length of the RF pulse as well as other parameters of the CEST pulse sequence to address the unique chemical shifts and exchange rates of the target, new targets with unique characteristics may be acquired using CEST MR imaging.01-26-2012

Liming Cai, West Chester, PA US

Patent application numberDescriptionPublished
20090140032Clamshell food container with sauce holder and carton blank therefor - A clamshell container and sauce holder for receiving a sauce container is constructed from a one-piece carton blank cut and scored to facilitate erection into a clamshell container with top and bottom portions hingedly connected along a common fold line. A bottom portion of the container includes an upper flat section extending inwardly from a bottom side wall, an integral support and a base member including a tuck flap for positioning the upper flat section. In addition, an opening is defined in the upper flat section for holding a sauce container.06-04-2009
20090266828Hot cup lid - A hot cup lid providing alternating modes of access to the contents of a cup, the lid including an enlarged drinking opening selectively closed by a tear flap, and a smaller sipping opening diametrically aligned with the drinking opening and adjacent the periphery of the lid, the tear flap including a sealing lug thereon engageable within and closing the sipping opening upon pivotal movement of the flap to open the drinking opening.10-29-2009

Patent applications by Liming Cai, West Chester, PA US

Lixia Cai, Maple Glen, PA US

Patent application numberDescriptionPublished
20100240925METHODS FOR MAKING UNSATURATED ACIDS USING CATALYSTS FOR METHACROLEIN OXIDATION - Methods for making unsaturated acids using catalysts for oxidation of unsaturated and/or Saturated aldehyde to unsaturated acids is disclosed where the catalyst including at least molybdenum (Mo) and phosphorus (P), where the catalyst has a pore size distribution including at least 50% medium pores and if bismuth is present, a nitric acid to molybdenum mole ratio of at least 0.5:1 or at least 6.0:1 moles of HNO09-23-2010
20100323882METHODS FOR PREPARING CATALYSTS FOR METHACROLEIN OXIDATION - Methods of making catalysts for oxidation of unsaturated and/or saturated aldehyde to unsaturated acids is disclosed where the catalyst including at least molybdenum (Mo) and phosphorus (P), where the catalyst has a pore size distribution including at least 50% medium pores and if bismuth is present, a nitric acid to molybdenum mole ratio of at least 0.5:1 or at least 6.0:1 moles of HNO12-23-2010
20110207600Method of Making Heteropoly Acid Compound Catalysts - The invention is for a method for making a heteropoly acid compound catalyst from compounds containing molybdenum, vanadium, phosphorus, cesium, copper, bismuth, antimony and boron in which molybdenum, vanadium, phosphorus, cesium, copper, bismuth and boron are at their highest oxidation states and antimony has a 3+ oxidation state. The catalyst contains oxides of molybdenum, vanadium, phosphorus, cesium, copper, bismuth, antimony, boron and, optionally, other metals. The catalyst has the formula:08-25-2011

Patent applications by Lixia Cai, Maple Glen, PA US

Shenshen Cai, Philadelphia, PA US

Patent application numberDescriptionPublished
20100015709Regulating Stem Cell Differentiation By Controlling 2D and 3D Matrix Elasticity - Provided are methods for the selection and regulation of the mechanical properties of 2D or 3D biocompatible substrates or tissue microenvironments as a technique to regulate in vitro differentiation, cell shape and/or lineage commitment of anchorage-dependent cells, such as mesenchymal stem cells into, e.g., neurogenic-, myogenic-, and osteogenic-type cells. Substrate mechanical properties include elasticity, tension, adhesion, and myosin-based contractile mechanisms. Inhibitors can be introduced to further regulate differentiation.01-21-2010

Yang Cai, Pittsburgh, PA US

Patent application numberDescriptionPublished
20100231734MULTIPLE RESOLUTION VIDEO NETWORK WITH CONTEXT BASED CONTROL - A system. The system includes a computing device configured for communication with a plurality of multiple resolution cameras and with a display device. The computing device includes a composite image module. The composite image module is configured for receiving composite information from at least one of the multiple resolution cameras, and for generating a composite image based on the composite information.09-16-2010
20100283843MULTIPLE RESOLUTION VIDEO NETWORK WITH EYE TRACKING BASED CONTROL - A system. The system includes a computing device configured for communication with a plurality of multiple resolution cameras and with a display device. The computing device includes a camera resolution module configured for instructing at least one of the multiple resolution cameras to operate at a first resolution at a first period of time and at a second resolution at a second period of time. The first resolution is different than the second resolution.11-11-2010

Zhauhui Cai, Garnet Valley, PA US

Patent application numberDescriptionPublished
20080213768Identification and use of biomarkers for non-invasive and early detection of liver injury - The present invention provides methods for identifying and evaluating suites of biochemical and/or gene entities useful as biomarkers for early prediction of disease and/or toxicity, disease staging, target identification/validation, and monitoring of drug efficacy/toxicity. The present invention further provides suites of small molecule entities as biomarkers for non-invasive and early prediction of hepatic injury.09-04-2008