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Caggiano, US
Anthony Caggiano, Larchmont, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110166068 | Therapeutic Dosing of a Neuregulin or a Subsequence Thereof for Treatment or Pro-phylaxis of Heart Failure - The invention relates to treatment of heart failure in a mammal. Accordingly, the invention is directed to establishing a dosing regimen whereby the therapeutic benefits conferred by administration of a neuregulin such as glial growth factor 2 (GGF2) or a subsequence thereof are maintained and/or enhanced, while concomitantly minimizing any potential side effects. | 07-07-2011 |
| 20110269682 | Compositions and Methods for Treatment During Non-Acute Periods Following CNS Neurological Injury - This invention relates to treatment of neuroinjury in a post-acute window or in a chronic period following neuroinjury. | 11-03-2011 |
Anthony G. Caggiano, Larchmont, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110250631 | PROTEOGLYCAN DEGRADING MUTANTS FOR TREATMENT OF CNS - The present disclosure relates to the preparation and deletion mutants of chondroitinase proteins and their use in methods for promoting the diffusion of therapeutic composition into tissues and their use for neurological functional recovery after central nervous system (“CNS”) injury or disease. | 10-13-2011 |
Anthony O. Caggiano, Hawthorne, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110085976 | METHODS FOR DETECTING CARDIAC DAMAGE - The present invention relates to a method for detecting heart damage in a patient. The invention also relates to methods for treatment of patients identified as having heart damage. The invention further pertains to methods for evaluating the efficacy of an ongoing therapeutic regimen designed to treat a damaged heart in a patient. | 04-14-2011 |
Robert Caggiano, Wolcott, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20120044600 | METHODS, SYSTEMS, AND APPARATUS FOR DETECTING ARC FLASH EVENTS USING CURRENT AND VOLTAGE - A power circuit protection system includes a current sensor configured to measure a first current level through a conductor of the circuit, a voltage sensor configured to measure a first voltage level across a plurality of conductors of the circuit, and a controller communicatively coupled to the current sensor and to the voltage sensor. The controller is configured to receive a first signal from the current sensor, wherein the first signal is representative of the first current level, and receive a second signal from the voltage sensor, wherein the second signal is representative of the first voltage level. Based on the first signal and the second signal, the controller is configured to determine whether to activate a first circuit protection device or a second circuit protection device. | 02-23-2012 |
Robert J. Caggiano, Wolcott, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20090161272 | ARC DETECTION SYSTEM AND METHOD - A system for identifying an arcing event in electrical distribution systems is provided. The system comprises a sensor configured to detect ultraviolet light and to generate a signal indicative of the arcing event propagating from the electrical distribution system. A processor coupled to the sensor and configured to analyze an ultraviolet light characteristic from the signal and generate an arc fault signal. A protective device configured to receive the arc fault signal and to mitigate the arcing event in the electrical distribution system. | 06-25-2009 |
Russell V. Caggiano, Fairless Hills, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20080317591 | CENTERLINE SUSPENSION FOR TURBINE INTERNAL COMPONENT - A centerline suspension arrangement ( | 12-25-2008 |
Thomas J. Caggiano, Morrisville, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090023801 | INHIBITORS OF BETA AMYLOID PRODUCTION - Novel sulfonamide compounds useful in the treatment of conditions related to the production of beta-amyloid are described, as are routes to their preparation. The sulfonamide compounds are of the following structure, wherein R | 01-22-2009 |
Thomas Joseph Caggiano, Morrisville, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20080249150 | HETEROCYCLIC SULFONAMIDE INHIBITORS OF BETA AMYLOID PRODUCTION CONTAINING AN AZOLE - Compounds useful for lowering beta amyloid levels are provided. The compounds have the structure of formula Ia: | 10-09-2008 |
| 20090221711 | TRIFLUOROMETHYL-CONTAINING PHENYLSULFONAMIDE BETA AMYLOID INHIBITORS - A compound of Formula (I), or pharmaceutically acceptable salts and/or hydrates or prodrugs thereof, wherein Formula (I) has the structure: | 09-03-2009 |
| 20100016639 | PRODUCTION OF CHIRALLY PURE AMINO ALCOHOL INTERMEDIATES, DERIVATIVES THEREOF, AND USES THEREOF - A method of selectively preparing a chiral 2S-amino alcohol useful in preparation of an amide sulfonated or acylated with alkyl, substituted aryl or substituted heteroaryl is described. The method involves reacting a di-tert-butyl diazene-1,2-dicarboxylate with a (4S)-4-benzyl-3-[(S)-trifluoromethyl-alkyl substituted alkanoyl]-1,3-oxazolidin-2-one to afford a di-tert-butyl 1-(1S,2S)-([(4S)-4-benzyl-2-oxo-1,3-oxazolidine-3-yl]-carbonyl}-trifluoromethyl-alkyl substituted alkyl)hydrazine-1,2-dicarboxylate. This dicarboxylate is then reduced to yield di-tert-butyl 1-(1S,2S)-[trifluoromethyl-alkyl substituted alkyl]hydrazine-1-(hydroxymethyl)-1,2-dicarboxylate. The resulting product is deblocked with an acid to yield the acid addition salt of (2S,3S)-trifluoro-hydrazino-methyl alkan-1-ol. The acid addition salt of (2S,3S)-trifluoro-2-hydrazino-methyl alkan-1-ol is hydrogenated in the presence of a suitable metal catalyst to yield the amino alcohol (2S,3S)-2-amino-trifluoro-methyl alkan-1-ol HCl. | 01-21-2010 |
| 20100144812 | Heterocyclic Sulfonamide Inhibitors of Beta Amyloid Production Containing an Azole - Compounds useful for lowering beta amyloid levels are provided. The compounds have the structure of formula Ia: | 06-10-2010 |