Patent application number | Description | Published |
20120277733 | DRUG-DELIVERY PUMPS AND METHODS OF MANUFACTURE - Embodiments of an implantable electrolytic pump include a first expandable diaphragm and a second flexible diaphragm, and first and second chambers each for containing a fluid, wherein the first expandable diaphragm separates the first and second chambers and provides a fluid barrier therebetween, and the second chamber is formed between the first expandable diaphragm and the second flexible diaphragms. The pump may further include electrolysis electrodes within the first chamber for causing generation of a gas therein and to thereby expand the expandable diaphragm so that fluid is forced from the second chamber into a cannula. | 11-01-2012 |
20120296423 | FILLING AND IMPLANTING ACCOMMODATIVE INTRAOCULAR LENSES - Advances in filling apparatus, handheld tools, surgical techniques and intraoperative biometry for implanting and adjusting an accommodative liquid lens are disclosed. The lens may be attached to or retained within a handheld surgical tool, which can be fluidly connectable to a filling console to fill the lens with a liquid. In various embodiments, a filling console facilitates aspirating liquid out of the lens in order to ensure the absence of residual bubbles and filling of the lens with fluid during surgery, as well as during post-operative adjustments to the lens. Actuated by the surgeon, the filling console can aspirate fluid from the lens and inject fluid into the lens following insertion thereof. | 11-22-2012 |
20120316540 | IMPLANTABLE DEVICE WITH CONFORMING TELEMETRY COIL AND METHODS OF MAKING SAME - A spiral-coil antenna conforming to a non-planar contour is deployed, in various embodiments, in an implantable device for controllably ejecting fluid into an anatomic region. The antenna facilitates wireless communications with the implantable device and external charging thereof. In one implementation, the device has a non-planar contour and the spiral coil defines a non-planar surface conforming to the non-planar contour. | 12-13-2012 |
20120323218 | DRUG-DELIVERY PUMPS AND METHODS OF MANUFACTURE - Embodiments of an implantable electrolytic pump include an electrolysis chamber, a drug chamber and an osmosis chamber, the osmosis chamber having a first portion in contact with the drug chamber and a second portion exposed to facilitate contact with a surrounding fluid. The pump further includes a cannula for conducting liquid from the drug chamber and electrolysis electrodes within the electrolysis chamber for causing generation of a gas therein, the electrolysis and drug chambers being in contact such that gas electrolysis within electrolysis chamber forces fluid from the drug chamber into the cannula, contact between the drug chamber and the osmosis chamber permitting fluid admitted into the osmotic chamber from the surrounding fluid to offset volume loss from the drug chamber and prevent buildup of vacuum pressure thereon. | 12-20-2012 |
20130090676 | Instruments and Methods for Surgical Sizing and Marking - A surgical sizer for creating a tissue pocket for an implantable medical device may include a replica of the device and a (preferably ergonomic) handle portion, optionally with marking features that facilitate marking the tissue for precise implant placement and alignment. | 04-11-2013 |
20130102962 | IMPLANTABLE DRUG-DELIVERY DEVICES, AND APPARATUS AND METHODS FOR FILLING THE DEVICES - In various embodiments, a tool is employed in filling a drug-delivery device. The tool may include, for example, a needle that is admitted through a fill port of the drug-delivery device. | 04-25-2013 |
20130116666 | IMPLANTABLE DRUG PUMPS AND REFILL DEVICES THEREFOR - A system for refilling the drug reservoir of an implanted drug pump device may facilitate wireless data exchange between the refill system and the implanted device, e.g., to verify proper drug selection prior to commencement of the refill process. | 05-09-2013 |
20130276974 | DRUG-DELIVERY PUMPS AND METHODS OF MANUFACTURE - Embodiments of method of manufacturing an implantable pump, including providing an upper layer comprising a dome structure for housing a drug chamber and a cannula in fluid communication with the drug chamber, providing a middle deflection layer adjacent the drug chamber, providing a bottom layer comprising electrolysis electrodes, and bonding the upper layer, middle deflection layer, and bottom layer to form the pump. | 10-24-2013 |
20130289497 | APPARATUS AND METHODS FOR DELIVERING THERAPEUTIC AGENTS - In various embodiments, a drug-delivery device includes one or more reservoirs that may each contain a therapeutic agent for delivery to a patient. | 10-31-2013 |
20130296810 | APPARATUS AND METHODS FOR DELIVERING THERAPEUTIC AGENTS - In various embodiments, a drug-delivery device includes one or more reservoirs that may each contain a therapeutic agent for delivery to a patient. | 11-07-2013 |
20140074058 | DRUG-DELIVERY PUMP WITH DYNAMIC, ADAPTIVE CONTROL - In various embodiments, actuation of a drug-delivery pump is controlled based on a change in a condition of the pump. | 03-13-2014 |
20140074062 | PISTON PUMP DEVICES - Drug pump devices with syringe or pen-injection configurations may utilize pre-filled drug vials or cartridges; the prefilled vials may be equipped with mechanisms for stirring their contents and/or changing a chemical environment therein to improve therapies. To facilitate combination therapies, multiple drug pump devices may be assembled into a larger system. Lancet insertion devices for use in conjunction with the drug pump devices may feature improved safety characteristics and/or mechanisms for minimizing pain and discomfort. | 03-13-2014 |
20140088508 | DRUG-DELIVERY DEVICES WITH INTEGRATED NEEDLE-INSERTION MECHANISM - Drug-delivery devices for subcutaneous injections may be provided with pre-filled drug reservoirs and/or integrated needle-insertion mechanisms to increase ease of use of the devices. Certain device configurations include a needle disposed above or below the drug vial, parallel to the bottom wall of the device, with the needle-insertion mechanism placed at least partially side-by side with the vial. | 03-27-2014 |
20140088554 | DRUG-DELIVERY PUMP WITH INTELLIGENT CONTROL - Embodiments of the present invention utilize a closed-loop feedback control system to ensure accurate drug delivery. This control system may, for example, utilize a flow sensor to measure the volume of delivery and an intelligent control algorithm to anticipate and compensate for overdoses and underdoses. Feedback control systems in accordance herewith can be applied to any piston- or plunger-driven pump system utilizing sensors that measure flow directly or indirectly. Depending on the mode of operation, fluid may be dispensed continuously or in discrete pulses, and the manner of adjustment or calibration may be tailored to the operational mode in use. | 03-27-2014 |
20140088555 | Systems and Methods for Electrolysis Pump Control - Drug-delivery devices may utilize electrolysis pumps to push a plunger so as to deliver drug from a reservoir. The volume and/or rate of drug delivery may be monitored based on pressure measurements in the pump chamber. Pressure signatures characteristic of end-of-dose and occlusion events may be used to detect when plunger movement stops. | 03-27-2014 |
20140094770 | DRUG-DELIVERY PUMP WITH INTELLIGENT CONTROL - Embodiments of the present invention utilize a closed-loop feedback control system to ensure accurate drug delivery. This control system may, for example, utilize a flow sensor to measure the volume of delivery and an intelligent control algorithm to anticipate and compensate for overdoses and underdoses. Feedback control systems in accordance herewith can be applied to any piston- or plunger-driven pump system utilizing sensors that measure flow directly or indirectly. In some embodiments, adjustments are made during a “priming” stage when liquid is pumped through the internal fluid path but does not exit the pump. | 04-03-2014 |
20140094771 | DRUG-DELIVERY PUMP WITH INTELLIGENT CONTROL - Embodiments of the present invention utilize a closed-loop feedback control system to ensure accurate drug delivery. This control system may, for example, utilize a flow sensor to measure the volume of delivery and an intelligent control algorithm to anticipate and compensate for overdoses and underdoses. Feedback control systems in accordance herewith can be applied to any piston- or plunger-driven pump system utilizing sensors that measure flow directly or indirectly. In some embodiments, adjustments are made based on the flow “tail” that occurs in a piston- or plunger-type pump as relaxation of the plunger material continues to push fluid out of the drug reservoir; this residual flow eventually ceases after the plunger returns to its natural state. | 04-03-2014 |
20140111765 | SYSTEMS AND METHODS FOR CUSTOMIZING ADJUSTABLE INTRAOCULAR LENSES - The lens geometry and power of an intraocular lens is optimized to provide both distance and near vision correction for a patient. The optimization may be based on one or more measured accommodation-related parameters and one or more estimated accommodation-related parameters. An accommodative amplitude may be predicted based on the measured and estimated accommodation-related parameters, and the optimized the intraocular lens geometry and power established based thereon. | 04-24-2014 |
20140285811 | OPTICAL COHERENCE TOMOGRAPHY WITH MULTIPLE SAMPLE ARMS - A multiplexed OCT imaging system includes a plurality of sample arms, an imaging engine, and an optical controller. The sample arms are optically coupled to the imaging engine via the optical controller; the optical controller multiplexes optical signals from the sample arms to permit some of the sample arms to operate sequentially or simultaneously. | 09-25-2014 |
20140358155 | INTRAOCULAR LENS PERIPHERAL SURGICAL SYSTEMS - Peripheral surgical systems are used for insertion and filling of fluid-filled intraocular lenses, reaccessing and modifying fluid-filled intraocular lenses, and explantation of lenses. Although one peripheral surgical unit may perform all of these functions, in some embodiments different units perform different functions—i.e., each function may be performed by a separate unit, or the functions may be distributed over a smaller number of functional units. | 12-04-2014 |