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Buxbaum
Darin Buxbaum, Palo Alto, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110245854 | DEVICES AND METHODS TO DELIVER, RETAIN AND REMOVE A SEPARATING DEVICE IN AN INTUSSUSCEPTED HOLLOW ORGAN - The present invention is an improved separating device for providing the malabsorptive component of a minimally invasive weight reduction system. This device may be a sleeve, liner, or tubular sheath that alters absorption of compositions through walls of hollow organs (stomach, intestines). The improvement involves better long-term retention through the ability of the device to engage with the interserosal fibrotic tissue formed in an intussusception. The separating device may be a distal extension of a retaining member that is directly engaged with and retained by intussuscepted tissue. Intussusception shrinks a hollow organ to provide a volume reducing restrictive component of a weight reduction system. Securing the separating device to an intussusception avoids retention problems of reference art devices as interserosal fibrosis helps secure the device. Also provided are an apparatus for retaining the device, a device and method for delivering the separating device, and a method for removing it. | 10-06-2011 |
Joseph D. Buxbaum, New York, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20120039812 | GENES ASSOCIATED WITH POSTTRAUMATIC-STRESS DISORDER (PTSD) - The present invention relates to a method of identifying a predisposition for developing posttraumatic stress disorder (PTSD) in a subject comprising assessing in a sample obtained from said subject the expression level of one or more genes selected from the FK506 binding protein 5 (FKBP5) gene, the signal transducer and activator of transcription (STAT5B) gene and the nuclear factor I/A (NFIA) gene, wherein a decrease in the expression level of said one or more genes as compared to the expression level of the corresponding gene(s) of a control is indicative of a predisposition for developing PTSD. Further, the invention relates to a method of identifying a compound capable of preventing or treating PTSD or capable of serving as a lead compound for developing a compound capable of preventing or treating PTSD and also to a method of selecting a therapy to prevent or treat PTSD. | 02-16-2012 |
Mark Buxbaum, Acton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100211953 | MANAGING TASK EXECUTION - Managing task execution includes: receiving a specification of a plurality of tasks to be performed by respective functional modules; processing a flow of input data using a dataflow graph that includes nodes representing data processing components connected by links representing flows of data between data processing components; in response to at least one flow of data provided by at least one data processing component, generating a flow of messages; and in response to each of the messages in the flow of messages, performing an iteration of a set of one or more tasks using one or more corresponding functional modules. | 08-19-2010 |
Robert E. Buxbaum, Oak Park, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20110114285 | COPPER-NIOBIUM, COPPER-VANADIUM, OR COPPER-CHROMIUM NANOCOMPOSITES, AND THE USE THEREOF IN HEAT EXCHANGERS - We propose here a class of new materials for high heat-flux applications including high flux heat exchangers, rocket engines, jet engines, gas turbines, space-plane wings, and fusion reactors. The materials are nano-composites formed from copper and a refractory metal, especially niobium, vanadium, or chromium, but also potentially silver, iron, tantalum, tungsten, or molybdenum. The copper plus refractory mix is fast-melted, e.g. by arc melting, and then fast-cooled and worked. When cast the component metals separate into a fractile metal-metal composite that should have excellent heat-transfer qualities. Working the material makes it a lot stronger by extending the fractile structures into micron, and submicron (nano-scale) filaments and sheets of metal-metal composite. The resulting strong, high thermal-conductivity material should be excellent for demanding heat exchange applications, especially those where the heat flux is so high that ordinary materials of construction would suffer from thermal creep: that is from large forces generated internally by the differential expansion caused by the heat flux. Typical heat exchanger surfaces that might use this material might be tubes or indented flat plates. | 05-19-2011 |