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Bush, MA
Ashley Bush, Somerville, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090297538 | NEUROTOXIC OLIGOMERS - This invention relates to methods and compositions for the treatment or alleviation of Alzheimer's disease and of other conditions related to abnormal protein aggregation. In particular, the invention relates to methods and compositions for the immunotherapy of Alzheimer's disease, Parkinson's disease, and cataract. In one aspect the invention provides a method of prophylaxis, treatment or alleviation of a condition characterized by pathological aggregation and accumulation of a specific protein associated with an immunizing-effective dose of one or more tyrosine cross-linked compounds, and optionally also comprising copper ions complexed to the compound. Alternatively passive immunization against a tyrosine cross-linked compound may be used. Prophylactic or therapeutic compositions and diagnostic methods are also disclosed and claimed. | 12-03-2009 |
David Bush, Somerville, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090017054 | NUCLEIC ACID AND AMINO ACID SEQUENCES RELATING TO STREPTOCOCCUS PNEUMONIAE FOR DIAGNOSTICS AND THERAPEUTICS - The invention provides isolated polypeptide and nucleic acid sequences derived from | 01-15-2009 |
| 20090074806 | NUCLEIC ACID AND AMINO ACID SEQUENCES RELATING TO STREPTOCOCCUS PNEUMONIAE FOR DIAGNOSTICS AND THERAPEUTICS - The invention provides isolated polypeptide and nucleic acid sequences derived from | 03-19-2009 |
| 20090148890 | Nucleic acid and amino acid sequences relating to streptococcus pneumoniae for diagnostics and therapeutics - The invention provides isolated polypeptide and nucleic acid sequences derived from | 06-11-2009 |
| 20090215149 | Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics - The invention provides isolated polypeptide and nucleic acid sequences derived from | 08-27-2009 |
| 20110020382 | Nucleic acid and amino acid sequences relating to staphylococcus epidermidis for diagnostics and therapeutics - The invention provides isolated polypeptide and nucleic acid sequences derived from | 01-27-2011 |
| 20110070626 | Nucleic acid and amino acid sequences relating to Staphylococcus epidermidis for diagnostics and therapeutics - The invention provides isolated polypeptide and nucleic acid sequences derived from | 03-24-2011 |
Katie A. Bush, Boston, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120116300 | ACTIVATION AND DELIVERY DEVICES FOR THERAPEUTIC COMPOSITIONS - Devices and methods for activating a therapeutic composition, delivering a therapeutic composition to a specific region or tissue in a body, and containing a therapeutic composition within a body cavity are disclosed herein. In one embodiment, a therapeutic capsule is shown having an outer element defining an interior chamber and including a matrix disposed therein and wherein the interior chamber is elongated along a chamber axis. | 05-10-2012 |
Katie A. Bush, Worcester, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110171180 | BIOENGINEERED SKIN SUBSTITUTES - A bioengineered skin substitute was developed that contains a microfabricated basal lamina analog that recapitulates the native microenvironment found at the dermal-epidermal junction (DEJ). | 07-14-2011 |
Larry R. Bush, Worcester, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100190861 | CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS - The invention relates to novel cyclohexylamine derivatives and their use in the treatment and/or prevention of central nervous system (CNS) disorders, such as depression, anxiety, schizophrenia and sleep disorder as well as methods for their synthesis. The invention also relates to pharmaceutical compositions containing the compounds of the invention, as well as methods of inhibiting reuptake of endogenous monoamines, such as dopamine, serotonin and norepinephrine from the synaptic cleft and methods of modulating one or more monoamine transporter. | 07-29-2010 |
Matthew F. Bush, Tyngsboro, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090160254 | SYSTEMS FOR AND METHODS OF CONTROLLING OPERATION OF A UPS - A UPS includes an AC output, power factor control circuitry; and a DC bus coupled to the power factor control circuitry where the power factor control circuitry is configured to determine a difference in instantaneous power supplied to the AC output and to adjust a voltage of the DC bus based, at least partly, on the difference. In one embodiment, the UPS includes a single phase AC input. In another embodiment, the power factor control circuitry is configured to determine a cumulative difference in instantaneous power supplied to the AC output. | 06-25-2009 |
Matthew Fletcher Bush, Tyngsboro, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110066696 | COMMUNICATION PROTOCOL - One aspect relates to a communication protocol for communicating between one or more entities, such as devices, hosts or any other system capable of communicating over a network. A protocol is provided that allows communication between entities without a priori knowledge of the communication protocol. In such a protocol, for example, information describing a data structure of the communication protocol is transferred between communicating entities. Further, an authentication protocol is provided for providing bidirectional authentication between communicating entities. In one specific example, the entities include a master device and a slave device coupled by a serial link. In another specific example, the communication protocol may be used for performing unbalanced transmission between communicating entities. | 03-17-2011 |
Michael Bush, Arlington, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110301757 | ADAPTABLE CONTAINER HANDLING ROBOT WITH BOUNDARY SENSING SUBSYSTEM - An adaptable container handling robot includes a chassis, a container transport mechanism, a drive subsystem for maneuvering the chassis, a boundary sensing subsystem configured to reduce adverse effects of outdoor deployment, and a controller subsystem responsive to the boundary sensing subsystem. The controller subsystem is configured to detect a boundary, control the drive subsystem to turn in a given direction to align the robot with the boundary, and control the drive subsystem to follow the boundary. | 12-08-2011 |