Burzio
Gianfranco Burzio, Orbassano IT
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20110264304 | MULTIUSER VEHICLE UTILIZATION SYSTEM AND ELECTRONIC KEY THEREOF - A vehicle utilization system and method permitting use of vehicles having respective identification codes includes a key having a memory for storing enabling codes enabling use of the vehicles; and an enabling device, in each vehicle, permitting use of the vehicle by a user in possession of the key, if the enabling code stored in the key meets given conditions. The system also includes a programming device for generating the enabling codes as a function of the identification codes of the vehicles, and for storing the generated enabling codes in the key. | 10-27-2011 |
Luis Burzio, Wentzville, MO US
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20100044268 | PHARMACEUTICAL PACKAGE HAVING A MULTI-FUNCTIONAL SURFACE AND A METHOD OF PREPARING A MULTI-FUNCTIONAL SURFACE ON A PHARMACEUTICAL PACKAGE - The present invention relates to a multi-functional pharmaceutical package surface and a method of preparing a multi-functional pharmaceutical package surface. In particular, the present invention relates to a pharmaceutical package having a protein deterrent and lubricious surface and methods of preparing said surface by applying coatings directly to the pharmaceutical package that (a) reduce the adsorption of proteins onto pharmaceutical packaging while not affecting the activity of the protein solution and (b) provide a lubricious surface. The pharmaceutical package surface may also contain a barrier coating. Coatings can be deposited on a variety of pharmaceutical packaging materials and configurations by various methods. | 02-25-2010 |
20110062047 | Method Of Preparing Macromolecule Deterrent Surface On a Pharmaceutical Packages - A method of preparing a macromolecule deterrent surface on a pharmaceutical package. In particular, the present invention relates to a method of preparing a protein deterrent surface on a pharmaceutical package by applying a coating or coatings directly to the pharmaceutical package that reduces the adsorption of proteins onto pharmaceutical packaging while not affecting the activity of the protein solution contained. | 03-17-2011 |
Luis Burzio, Santiago CL
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20130149371 | MARKERS FOR PRE-CANCER AND CANCER CELLS AND THE METHOD TO INTERFERE WITH CELL PROLIFERATION THEREIN - A novel family of human mitochondrial RNAs, referred to as chimeric RNAs, which are differentially expressed in normal, pre-cancer and cancer cells, are described. Oligonucleotides targeted to the chimeric RNAs are provided. The described oligonucleotides or their analogs can be used for cancer diagnostics and cancer therapy as well as for research. In one embodiment of this invention, these oligonucleotides hybridize with the sense or with the antisense mitochondrial chimeric RNAs, and the result of the hybridization is useful to differentiate between normal proliferating cells, pre-cancer cells and cancer cells. In another embodiment of the invention, the compositions comprise oligonucleotides that hybridize with the human chimeric RNAs resulting in cancer cell and pre-cancer cell death, while there is no effect in normal cells, constituting therefore, a novel approach for cancer therapy. | 06-13-2013 |
20150064700 | MARKERS FOR PRE-CANCER AND CANCER CELLS AND THE METHOD TO INTERFERE WITH CELL PROLIFERATION THEREIN - A novel family of human mitochondrial RNAs, referred to as chimeric RNAs, which are differentially expressed in normal, pre-cancer and cancer cells, are described. Oligonucleotides targeted to the chimeric RNAs are provided. The described oligonucleotides or their analogs can be used for cancer diagnostics and cancer therapy as well as for research. In one embodiment of this invention, these oligonucleotides hybridize with the sense or with the antisense mitochondrial chimeric RNAs, and the result of the hybridization is useful to differentiate between normal proliferating cells, pre-cancer cells and cancer cells. In another embodiment of the invention, the compositions comprise oligonucleotides that hybridize with the human chimeric RNAs resulting in cancer cell and pre-cancer cell death, while there is no effect in normal cells, constituting therefore, a novel approach for cancer therapy. | 03-05-2015 |
Luis A. Burzio, Wentzville, MO US
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20080213909 | PHARMACEUTICAL PACKAGING ASSAY - A pharmaceutical packaging assay for the determination of drug adsorption to the packaging surface(s) is described. The assay described utilizes fluorescent labeling of drugs in various formulations to determine the best packaging surface for drug stability as a function of adsorption. | 09-04-2008 |
Luis Alberto Burzio, Wentzville, MO US
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20110177955 | MULTIPLEXED PROTEIN ADSORPTION ASSAY - A multiplexed assay method capable of measuring the interaction of one or more protein, polypeptide or peptide solutions with one or more substrate surfaces comprises contacting each of the wells of a multiwell substrate with the same or different protein solution, the surfaces of said wells being the same as that of said substrate or being substrate surface treated and/or coated to provide test surfaces, and determining the level of protein adsorption in each of said wells. | 07-21-2011 |
Luis O. Burzio, Santiago CL
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20110287515 | PROTEIN AND DNA SEQUENCE ENCODING A COLD ADAPTED XYLANASE - A method of preparing a cold adapted xylanase by use of recombinant DNA techniques. A nucleic acid and corresponding amino acid sequences of a cold adapted xylanase, isolated from antarctic marine origin, preferably from an Antarctic bacteria ( | 11-24-2011 |
20120264191 | PROTEIN AND DNA SEQUENCE ENCODING A COLD ADAPTED-SUBTILISIN-LIKE ACTIVITY - Nucleic acid and corresponding amino acid sequences of a cold adapted subtilisin-like activity protein, insolated from antarctic marine origin, preferably from an Antarctic bacteria ( | 10-18-2012 |
Matteo Burzio, Fiorano Modense IT
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20100015377 | Model at a Reduced Scale of a Tire for Aerodynamic Tests in a Wind Tunnel - A reduced scale model of a tire for aerodynamic tests in a wind tunnel, the model having a hollow toroidal shape, is made of a single moulded plastic material homogeneous throughout the model, is deformable, and is shaped so as to reproduce externally the deformed shape of the tire under load when this is set in conditions of operation under the action of centrifugal loads and/or ground loads. | 01-21-2010 |
Veronica A. Burzio, Santiago CL
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20130149371 | MARKERS FOR PRE-CANCER AND CANCER CELLS AND THE METHOD TO INTERFERE WITH CELL PROLIFERATION THEREIN - A novel family of human mitochondrial RNAs, referred to as chimeric RNAs, which are differentially expressed in normal, pre-cancer and cancer cells, are described. Oligonucleotides targeted to the chimeric RNAs are provided. The described oligonucleotides or their analogs can be used for cancer diagnostics and cancer therapy as well as for research. In one embodiment of this invention, these oligonucleotides hybridize with the sense or with the antisense mitochondrial chimeric RNAs, and the result of the hybridization is useful to differentiate between normal proliferating cells, pre-cancer cells and cancer cells. In another embodiment of the invention, the compositions comprise oligonucleotides that hybridize with the human chimeric RNAs resulting in cancer cell and pre-cancer cell death, while there is no effect in normal cells, constituting therefore, a novel approach for cancer therapy. | 06-13-2013 |
20150064700 | MARKERS FOR PRE-CANCER AND CANCER CELLS AND THE METHOD TO INTERFERE WITH CELL PROLIFERATION THEREIN - A novel family of human mitochondrial RNAs, referred to as chimeric RNAs, which are differentially expressed in normal, pre-cancer and cancer cells, are described. Oligonucleotides targeted to the chimeric RNAs are provided. The described oligonucleotides or their analogs can be used for cancer diagnostics and cancer therapy as well as for research. In one embodiment of this invention, these oligonucleotides hybridize with the sense or with the antisense mitochondrial chimeric RNAs, and the result of the hybridization is useful to differentiate between normal proliferating cells, pre-cancer cells and cancer cells. In another embodiment of the invention, the compositions comprise oligonucleotides that hybridize with the human chimeric RNAs resulting in cancer cell and pre-cancer cell death, while there is no effect in normal cells, constituting therefore, a novel approach for cancer therapy. | 03-05-2015 |