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Burnet
Michael Burnet, Tubingen DE
| Patent application number | Description | Published |
|---|---|---|
| 20110044901 | NOVEL COMPOUNDS - The present invention is directed to sulphated compounds comprising at least one glycosidic amine group, and polysaccharide, oligosaccharide, peptide and protein derivatives comprising such compounds, and mixtures thereof. The present invention is also directed to methods of synthesising such compounds. Such compounds may bind to a range of proteins, find application in methods of modifying, or testing for a modification in the level of a cytokine in vivo, ex vivo or in vitro, and find application in the treatment and/or prevention of inflammation, an inflammatory disorder, a proliferative disorder, an immune disorder, an angiogenesis-dependent disorder, a sensitivity disorder, an adverse endocrine reaction, a degenerative disorder, wound healing, depression, and other diseases and disorders. | 02-24-2011 |
Michael Burnet, Kusterdingen DE
| Patent application number | Description | Published |
|---|---|---|
| 20090093014 | Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof - This invention features a method of identifying a compound useful for enhancing efficacy of a therapeutic agent. The method includes incubating a compound in blood cells; separating immune cells from erythrocytic cells; and determining the ratio of the concentration of the compound in the immune cells to the concentration of the compound in the erythrocytic cells; wherein the compound comprises a transportophore and a therapeutic agent, in which the transportophore is covalently bonded to the therapeutic agent via a bond or a linker. | 04-09-2009 |
| 20110028417 | Macrocyclic Compounds and Methods of Use Thereof - The invention features novel macrocyclic compounds, methods of making the compounds, pharmaceutical compositions including the compounds, and methods of treatment using the compounds. | 02-03-2011 |
Michael Burnet, Tuebingen DE
| Patent application number | Description | Published |
|---|---|---|
| 20090221697 | MACROLIDE CONJUGATES OF PYRROLIZINE AND INDOLIZINE COMPOUNDS AS INHIBITORS OF 5-LIPOOXYGENASE AND CYCLOOXYGENASE - The present invention relates to macrolide conjugates of pyrrolizine and indolizine derivatives with macrocyclic antibiotics and derivatives thereof. The macrolide conjugates are potent inhibitors of 5-lipoxygenase and cyclooxygenase and are therefore suitable to treat disorders of the rheumatic type and to prevent allergically induced diseases. The macrolide conjugates have significantly enhanced potency and efficacy. | 09-03-2009 |
| 20090270462 | 2-SULFANYL-SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR USE AS CYTOKINE INHIBITORS - The invention relates to 2-thio-substituted imidazole derivatives of the Formula I, and to methods of use thereof. | 10-29-2009 |