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Burczynski
Daniel E. Burczynski, Horseheads, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100132806 | FIRE HYDRANT CHECK VALVE - A check valve for a fire hydrant system is configured to allow fluid to flow in a direction from a pressurized water supply to a fire hydrant and to restrict fluid from flowing from the fire hydrant to the pressurized water supply. The check valve includes an internal cavity and a flapper capable of moving between an open position wherein the flapper is positioned against a side of the internal cavity so as to substantially not impede flow of fluid therethrough and a closed position wherein the flapper creates a seal to restrict flow of fluid therethrough. | 06-03-2010 |
Frank J Burczynski, Winnipeg CA
| Patent application number | Description | Published |
|---|---|---|
| 20080207713 | Compositions and Methods For Enhancing Nitric Oxide Delivery - The present invention is directed to compounds, combinations, compositions and methods for enhancing nitric oxide (NO) delivery to target sites, and in particular to muscle, both normal and dystrophic. Enhanced NO delivery according to the present invention may be achieved by using a combination of a muscle relaxant and an NO donor compound, or by using a compound of the invention: formula (I) wherein R | 08-28-2008 |
Michael E. Burczynski, Cedar Knolls, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100081666 | SRC ACTIVATION FOR DETERMINING CANCER PROGNOSIS AND AS A TARGET FOR CANCER THERAPY - Methods of cancer diagnosis and prognosis using biomarkers. | 04-01-2010 |
Michael E. Burczynski, Collegeville, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090142763 | NESTED PCR-BASED METHOD FOR SPECIFIC GENOTYPING OF THE FC GAMMA RECEPTOR IIIA GENE - The application describes a novel method for detection of a single nucleotide polymorphism, e.g., the 158 F/V polymorphism, in the FcγRIIIa gene using nested PCR to amplify large gene amplicons to aid in, e.g., genotyping applications. Thus, based on the results obtained in FcγRIIIa genotyping analysis, the present invention provides specific, efficient, reproducible, and accurate detection of such polymorphisms in genomic DNA. | 06-04-2009 |
Michael Edward Burczynski, Collegeville, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20080226645 | Methods and compositions for assessment and treatment of asthma - The present invention provides methods and compositions for the assessment and treatment of asthma and other inflammatory diseases, particularly those mediated by interleukin-13 (IL-13). The present invention also provides arrays comprising markers for asthma as well as IL-13 responsiveness. The markers of the present invention can be used in methods to diagnose a patient as having asthma or an IL-13-mediated condition, to evaluate the effectiveness of potential therapeutic agents, to identify or evaluate agents capable of modulating marker expression levels, and to select a treatment for a patient suffering from asthma or an IL-13-mediated condition. | 09-18-2008 |
| 20080280774 | Methods and Systems for Diagnosis, Prognosis and Selection of Treatment of Leukemia - The present invention provides methods, systems and equipment for the prognosis, diagnosis and selection of treatment of AML or other types of leukemia. Genes prognostic of clinical outcome of leukemia patients can be identified according to the present invention. Leukemia disease genes can also be identified according to the present invention. These genes are differentially expressed in PBMCs of AML patients relative to disease-free humans. These genes can be used for the diagnosis or monitoring the development, progression or treatment of AML. | 11-13-2008 |
| 20090061423 | PHARMACOGENOMIC MARKERS FOR PROGNOSIS OF SOLID TUMORS - The present invention provides methods, systems and equipment for prognosis or evaluation of treatment of solid tumors. Gene markers that are prognostic of solid tumors can be identified according to the present invention. Each gene marker has altered expression patterns in PBMCs of solid tumor patients following initiation of an anti-cancer treatment, and the magnitudes of these alterations are correlated with clinical outcomes of these patients. In one embodiment, a Cox proportional hazards model is used to determine the correlations between clinical outcomes of RCC patients and gene expression changes in PBMCs of these patients during the course of a CCI-779 treatment. Non-limiting examples of genes identified by the Cox model are depicted in Tables 4A3 4B, 5 A and 5B. These genes can be used as surrogate markers for prognosis of RCC. They can also be used as pharmacogenomic indicators for the efficacy of CCI-779 or other anti-cancer drugs. | 03-05-2009 |
Thomas J. Burczynski, Montour Falls, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20120096754 | BREECH PLUG CLEANING TOOL - A cleaning tool set is used to clean carbon build-up from a breech plug. The cleaning tool set includes a first tool configured to remove the carbon buildup from the primer pocket and intermediate flash channel of the breech plug and a second tool configured to remove carbon buildup from the flash hole of the breech plug. | 04-26-2012 |