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Buckle
Andrew Buckle, Berowra AU
| Patent application number | Description | Published |
|---|---|---|
| 20120058105 | METHOD OF TREATMENT OF VASCULAR COMPLICATIONS - The present invention provides methods for the prevention or treatment of one or more vascular complication(s) in a subject at risk of developing diabetes mellitus, impaired glucose tolerance and/or hyperglycemia or a subject suffering from diabetes mellitus, impaired glucose tolerance and/or hyperglycemia, wherein an amount of a composition effective to inhibit, repress, delay or otherwise reduce expression and/or activity and/or level of TXNIP and/or an amount of a composition effective to induce, enhance or otherwise increase expression and/or activity and/or level of TRX is/are administered to a subject in need thereof. The present invention also provides methods for identifying and isolating modulators of TXNIP expression and/or activity and/or level and/or TRX expression and/or activity and/or level for use in such therapeutic and prophylactic methods. | 03-08-2012 |
Ashley Maurice Buckle, Mt. Dandenong AU
| Patent application number | Description | Published |
|---|---|---|
| 20100216112 | Crystal structures of both isoforms of human glutamic acid decarboxylase - A crystal comprising an isoform of an N-terminal truncation of GAD chosen from the group consisting of a monoclinic P2 | 08-26-2010 |
| 20110311511 | CRYSTAL STRUCTURE OF PfA-M1 AND THE PfA-M1 Co4 COMPLEX - The invention relates to the X-ray crystal structure of PfA-M1 aminopeptidase alone, and in complex with the phosphinate dipeptide analogue hPheP[CH | 12-22-2011 |
Ashley Maurice Buckle, Victoria AU
| Patent application number | Description | Published |
|---|---|---|
| 20090092555 | Octameric Protein For Use In Bionanotechnology Applications - The present invention relates to purified multimeric proteins, comprising PlyCB monomers or functional fragments or variants thereof, which self-assemble into a ring like structure. The present invention also encompasses such multimeric proteins that comprise an integrin-binding sequence. The present invention further discloses contrast reagents, implant coatings, bone implants, and complexes for use in bionanotechnology applications, each of which comprise such multimeric proteins. | 04-09-2009 |
Charles J. Buckle, Hillsborough, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20090166178 | METHODS FOR STERILIZING MATERIALS CONTAINING BIOLOGICALLY ACTIVE AGENTS - Provided are methods for sterilizing a material comprising a biologically-active agent comprising irradiating said material with ionizing radiation at a dose of about 5 kGy to about 25 kGy while maintaining said material in an atmosphere comprising at least 95% by volume inert gas and at a temperature of about 4° C. or lower. Also provided are sterilized materials comprising a biologically-active agent, wherein said materials exhibit substantially the same amount of biological activity as a non-sterilized control. | 07-02-2009 |
Dwight K. Buckle, Guelph CA
| Patent application number | Description | Published |
|---|---|---|
| 20080272510 | Method and Apparatus for Directly Injecting Steam in an Expanded Plastic Material Mold - A traditional steam chest molding apparatus for the manufacture of products from expanded plastic materials requires excessive amounts of steam to properly expand and fuse pellets of plastic together A molding apparatus is provided wherein a pair of complementary molds ( | 11-06-2008 |
Ian Buckle, Eindhoven NL
| Patent application number | Description | Published |
|---|---|---|
| 20080198540 | Protective Cover For Flexible Display Screen - In a device ( | 08-21-2008 |
Kenneth Ricky Buckle, Flat Rock CA
| Patent application number | Description | Published |
|---|---|---|
| 20080289494 | DECOMPOSITION OF NATURAL GAS OR METHANE USING COLD ARC DISCHARGE - The invention provides methods and apparatus for a cold arc discharge used to decompose natural gas or methane into its gaseous constituents and carbon in the form of solid particles. The gaseous constituents obtained are mainly hydrogen and acetylene and they are produced in admixture with unreacted natural gas or methane. | 11-27-2008 |
| 20090038933 | Decomposition of Natural Gas or Methane Using Cold Arc Discharge - A cold arc discharge is used to decompose natural gas or methane into its gaseous constituents and carbon in the form of solid particles. The gaseous constituents obtained are mainly hydrogen and acetylene and they are produced in admixture with unreacted natural gas or methane. The cold arc discharge is generated by a pulsating high voltage discharge imparted through a capacitor to a high voltage electrode or a plurality of high voltage electrodes or through a high voltage electrode to a plurality of capacitor—connected electrodes placed in a reaction zone. The apparatus for performing this process may have a tubular reactor with a cylindrical ground electrode in the middle and a cylindrical outer wall through which the high voltage electrode or electrodes extend into the reaction zone. The apparatus may also have a cylindrical shaft in the middle made of dielectric material in which a plurality of electrodes are embedded, this shaft being surrounded by a high voltage tubular electrode. Natural gas or methane is passed through the reaction zone where it is subjected to the cold arc discharge or discharges and the resulting products flow out of the reactor and solid carbon particles are separated from the remaining gases that are then analysed. | 02-12-2009 |
Kevin G. Buckle, Aberdeenshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20080230229 | Method of Running a Tubing Hanger and Internal Tree Cap Simultaneously - During the completion of a subsea horizontal tree, a tubing hanger and internal tree cap are run together with the same running tool and running string. The running tool has a linking assembly that connects the tree cap to the tubing hanger during running, retrieval, or workover, so that the tree cap supports the weight of the tubing hanger and string of tubing. The linking assembly can be retrieved with the running tool or retrieved on wireline through the running string. | 09-25-2008 |
| 20090071656 | METHOD OF RUNNING A TUBING HANGER AND INTERNAL TREE CAP SIMULTANEOUSLY - An assembly for the completion of a subsea horizontal tree that includes a tubing hanger, an internal tree cap, and a running tool. | 03-19-2009 |
| 20100307764 | Bimetallic Diaphragm for Trapped Fluid Expansion - A subsea well tubular member has an axial passage with upper and lower retrievable plugs releasably mounted in the passage, the plugs having ends facing each other. A cavity is formed on one of the ends of one of the plugs. A movable barrier is mounted sealingly over the cavity, the barrier being movable repeatedly between inner and outer positions in response to temperature changes. The inner position reduces a volume of the cavity and increases a volume of a trapped fluid space between the ends of the plugs. The outer position increases the volume of the cavity and decreases the volume of the trapped fluid space. The barrier has two metallic layers with different coefficients of expansion. | 12-09-2010 |
| 20110120697 | METAL-TO-METAL SEAL WITH WIPER ELEMENT AND WELLHEAD SYSTEM INCORPORATING SAME - A wellhead or Christmas tree seal assembly that forms a metal-to-metal seal between inner and outer wellhead or Christmas tree members. U-shaped metal seals having legs that face in opposite directions, are bonded to a wiping element. During installation of the seal assembly, the ends of the seal legs seal against the wellhead members and the wiping element compensates for defects on the surfaces of the wellhead members. The wiping element can be of an elastomer, metallic, or intercalated graphite material. | 05-26-2011 |