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Buchsbaum, US

Daphna Buchsbaum, Berkeley, CA US

Patent application numberDescriptionPublished
20090144617METHOD AND SYSTEM FOR FAST, GENERIC, ONLINE AND OFFLINE, MULTI-SOURCE TEXT ANALYSIS AND VISUALIZATION - Methods and systems for text data analysis and visualization enable a user to specify a set of text data sources and visualize the content of the text data sources in an overview of salient features in the form of a network of words. A user may focus on one or more words to provide a visualization of connections specific to the focused word(s). The visualization may include clustering of relevant concepts within the network of words. Upon selection of a word, the context thereof, e.g., links to articles where the word appears, may be provided to the user. Analyzing may include textual statistical correlation models for assigning weights to words and links between words. Displaying the network of words may include a force-based network layout algorithm. Extracting clusters for display may include identifying “communities of words” as if the network of words was a social network.06-04-2009
20110047455Method and System for Fast, Generic, Online and Offline, Multi-Source Text Analysis and Visualization - Methods and systems for text data analysis and visualization enable a user to specify a set of text data sources and visualize the content of the text data sources in an overview of salient features in the form of a network of words. A user may focus on one or more words to provide a visualization of connections specific to the focused word(s). The visualization may include clustering of relevant concepts within the network of words. Upon selection of a word, the context thereof, e.g., links to articles where the word appears, may be provided to the user. Analyzing may include textual statistical correlation models for assigning weights to words and links between words. Displaying the network of words may include a force-based network layout algorithm. Extracting clusters for display may include identifying “communities of words” as if the network of words was a social network.02-24-2011

Daphna Buchsbaum, Somerville, MA US

Patent application numberDescriptionPublished
20090070320Methods and Apparatus for Interactive Name Searching Techniques - Methods and apparatus include presenting an initial set of names to a user. The user selects a set of names from those presented. An Interactive Evolutionary Algorithm (IEA) extracts features of each selected name from a database of names and features to form a feature set. The IEA forms a set of match features that are chosen from the feature set according to a priority function and/or weighting of the features, either of which may vary in succeeding iterations. The IEA searches the database to obtain a candidate set of names, where each name has features matching the match features. One or more names is chosen from the candidate set and added into a presentation set of names. The IEA may repeat the formation of the match features, candidate set, and selection of one or more names from the candidate set until the new presentation set is complete.03-12-2009

Donald J. Buchsbaum, Alabaster, AL US

Patent application numberDescriptionPublished
20090022707Combinations of Antibodies Selective for a Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Receptor and Other Therapeutic Agents - An antibody of the invention interacts with human DR5 or with human DR4 to produce agonistic or antagonistic effects downstream of the receptor including inhibition of cell proliferation and apoptosis. Methods and uses for the antibodies, optionally in combination with various therapeutic agents, are detailed, including treatment of apoptosis-related disease and treatment of dysregulated cell growth.01-22-2009
20090208483ANTIBODY SELECTIVE FOR DR4 AND USES THEREOF - An antibody of the invention interacts with human DR5 or with human DR4 to produce agonistic or antagonistic effects downstream of the receptor including inhibition of cell proliferation and apoptosis. Nucleic acid sequences and amino acid sequences of DR5 and DR4 antibodies have been elucidated and vectors and cells containing and expressing these sequences have been generated. Methods and uses for the antibodies are detailed including treatment of apoptosis-related disease and treatment of dysregulated cell growth.08-20-2009
20110002887COMBINATIONS OF ANTIBODIES SELECTIVE FOR DR5 AND OTHER THERAPEUTIC AGENTS - An antibody of the invention interacts with human DR5 or with human DR4 to produce agonistic or antagonistic effects downstream of the receptor including inhibition of cell proliferation and apoptosis. Methods and uses for the antibodies, optionally in combination with various therapeutic agents, are detailed, including treatment of apoptosis-related disease and treatment of dysregulated cell growth.01-06-2011
20110104143Treating Basal-Like Genotype Cancers - Provided herein are methods of treating a subject with cancer comprising administering to the subject a death receptor agonist. Also provided herein are methods of screening a breast cancer cell for responsiveness to a DR5 agonist. Further provided herein are antibodies that selectively bind an N-terminal CARD of DDX3, a DDX3 lacking an N-terminal CARD, and an 80 kDa baculovirus TAP repeat (BIR).05-05-2011

Patent applications by Donald J. Buchsbaum, Alabaster, AL US

Donald Jay Buchsbaum, Birmingham, AL US

Patent application numberDescriptionPublished
20090297509Treatment of human tumors with radiation and inhibitors of growth factor receptor tyrosine kinases - A method to inhibit the growth of tumors in human patients, comprising treating the human patients with an effective amount of a combination of radiation and a non-radiolabeled protein receptor tyrosine kinase inhibitor, the overexpression of which can lead to tumorigenesis.12-03-2009