Patent application number | Description | Published |
20140171680 | ANAEROBIC CONVERSION OF 4-CARBOXYBENZALDEHYDE IN IONIC LIQUIDS - A method of decreasing an amount of an aromatic aldehyde in a product is described. The method includes reacting the aromatic aldehyde in the presence of a reaction medium comprising a nucleophilic solvent, or an ionic liquid and a carboxylic acid, the reaction taking place in the absence of a hydrogenating agent and an oxidizing agent, to form aromatic carboxylic acid, an aromatic alcohol, or both. | 06-19-2014 |
20150094486 | ACTIVE IONIC LIQUID MIXTURES FOR OXIDIZING ALKYLAROMATIC COMPOUNDS - Ionic liquid compositions derived from imidazolium based ionic liquids that have been thermally treated or thermally and oxidatively treated are disclosed. These compositions can be utilized as the medium for oxidation of alkylaromatic compounds and their oxidized derivatives or as a medium for purification of aromatic carboxylic acids. | 04-02-2015 |
20150099897 | PROCESS FOR CONTROLLING REACTION AND CRYSTALLIZATION SOLVENT COMPOSITION IN PROCESS FOR PRODUCTION OF AROMATIC CARBOXYLIC ACID - Processes have been developed to obtain recycle ionic liquid streams which are active for oxidation of alkyl aromatic compounds, and which reduce the amount of 4-CBA in the solid oxidation products. The process can reduce the makeup amount of ionic liquid, carboxylic acid, catalyst, bromine source, and ammonia source. | 04-09-2015 |
20150099898 | PROCESS FOR REMOVING AMIDE IMPURITIES IN AROMATIC CARBOXYLIC ACIDS - A process for oxidizing alkyl aromatic compounds is described. The alkyl aromatic compound is oxidized producing an aromatic carboxylic acid, and an aromatic amide compound. The aromatic amide compound is then hydrolyzed with a hydrolyzing agent to the aromatic carboxylic acid. | 04-09-2015 |
20150273460 | REGENERATION OF AN ACIDIC CATALYST BY ALKYLATION OF AROMATIC COMPOUNDS - Methods for regenerating deactivated acidic catalyst containing conjunct polymer are described. The deactivated acidic catalyst containing conjunct polymer is contacted with at least one aromatic compound in a regeneration zone under regeneration conditions. The conjunct polymer reacts with the at least one aromatic compound resulting in a regenerated acidic catalyst and at least one aromatic compound alkylated with conjunct polymer. The acidic catalyst is selected from the group consisting of sulfuric acid, hydrofluoric acid, trifluoromethanesulfonic acid, phosphoric acid, boron trifluoride, toluenesulfonic acid, trifluoroacetic acid, and acidic ionic liquids. | 10-01-2015 |
20150274614 | METHOD FOR RECOVERING ENTRAINED IONIC LIQUID FROM AN IONIC LIQUID IMMISCIBLE PHASE - A method for recovering entrained ionic liquid from an immiscible phase containing droplets of ionic liquid is described. The method includes contacting the immiscible phase containing the droplets of ionic liquid with a scrubbing ionic liquid phase in a scrubbing zone. The immiscible phase containing the droplets of ionic liquid has a first level of droplets of ionic liquid. At least a portion of the droplets of ionic liquid are transferred to the scrubbing ionic liquid phase to form a recovered ionic liquid phase comprising the scrubbing ionic liquid and the transferred portion of the droplets of ionic liquid and a second immiscible phase having a second level of droplets of ionic liquid lower than the first level. The second immiscible phase is separated from the recovered ionic liquid phase. | 10-01-2015 |
Patent application number | Description | Published |
20080228201 | MITRAL VALVE REPAIR SYSTEM AND METHOD FOR USE - The present invention is directed to various systems for repairing tissue within the heart of a patient. The mitral valve repair system of the present invention comprises a guide catheter having a proximal end, a distal end, and at least one internal lumen formed therein, a therapy catheter capable of applying a suture to the tissue, and a fastener catheter capable of attaching a fastener to the suture. The therapy catheter and the fastener catheter are capable of traversing the internal lumen of the guide catheter. In addition, the present invention discloses various methods for repairing tissue within the heart of a patient. In one embodiment, the method of repairing heart valve tissue includes advancing a guide catheter through a circulatory pathway to a location in the heart proximate to a heart valve, advancing a therapy catheter through the guide catheter to the heart valve, stabilizing a first leaflet with the therapy catheter, deploying a first suture into the stabilized first leaflet, disengaging the first leaflet from the therapy catheter while leaving the first suture attached thereto, stabilizing a second leaflet with the therapy catheter, deploying a second suture into the second leaflet, disengaging the second leaflet from the therapy catheter while leaving the second suture attached thereto, and joining the first and second leaflets by reducing the distance between the first and second sutures. | 09-18-2008 |
20090125056 | SYSTEMS AND METHODS FOR PUNCTURE CLOSURE - Systems, apparatuses and methods are provided for use in closing punctures in vessel walls. An apparatus may have various combinations of an anchoring device, a positioning device and a heating element for closing a puncture within a vessel wall. An anchoring device may be a balloon, an expansible cage, a wire operated T-anchor, and/or a floating anchor. A positioning device may be a balloon, a sponge, and/or an expansible cage. A heating element may be flexible or rigid and preferably provides heat to target tissue through conduction and convection. A heating element may be flat-ended or dome-shaped. The heating element and anchoring device may be positioned a fixed distance apart to sandwich tissue between the heating element and the anchoring device. The heating element may operate in multiple stages. An initial stage may non-permanently adhere the heating element to the tissue and the subsequent stage may close the puncture. | 05-14-2009 |
20090318871 | MITRAL VALVE REPAIR SYSTEM AND METHOD FOR USE - The present invention is directed to various systems for repairing tissue within the heart of a patient. The mitral valve repair system of the present invention comprises a guide catheter having a proximal end, a distal end, and at least one internal lumen formed therein, a therapy catheter capable of applying a suture to the tissue, and a fastener catheter capable of attaching a fastener to the suture. The therapy catheter and the fastener catheter are capable of traversing the internal lumen of the guide catheter. In addition, the present invention discloses various methods for repairing tissue within the heart of a patient. In one embodiment, the method of repairing heart valve tissue includes advancing a guide catheter through a circulatory pathway to a location in the heart proximate to a heart valve, advancing a therapy catheter through the guide catheter to the heart valve, stabilizing a first leaflet with the therapy catheter, deploying a first suture into the stabilized first leaflet, disengaging the first leaflet from the therapy catheter while leaving the first suture attached thereto, stabilizing a second leaflet with the therapy catheter, deploying a second suture into the second leaflet, disengaging the second leaflet from the therapy catheter while leaving the second suture attached thereto, and joining the first and second leaflets by reducing the distance between the first and second sutures. | 12-24-2009 |
20110196412 | BALLOONS AND BALLOON CATHETER SYSTEMS FOR TREATING VASCULAR OCCLUSIONS - A balloon catheter system for the intraluminal advancement of conventional guidewires beyond partially or fully occluded or stenosed lesions in body passages, such as CTOs in the vasculature, is provided. Balloons are provided. In certain embodiments of the invention, a balloon having relatively thickened proximal tapers is provided. In certain embodiments of the invention, balloons having a tapered midsection are provided. The balloons are preferably useful with crossing balloon catheter systems. In certain embodiments of the invention, the balloons preferably reduce or minimize trauma to the vascular wall or wall of other body passage in which it is used. | 08-11-2011 |
20120123531 | PERCUTANEOUS TRANSCATHETER REPAIR OF HEART VALVES - Apparatus, systems, and methods are provided for repairing heart valves through percutaneous transcatheter delivery and fixation of annuloplasty rings to heart valves. An annuloplasty ring includes an outer hollow member including a plurality of segments. Adjacent segments cooperate with one another to change the outer hollow member from an elongate insertion geometry to an annular operable geometry. The annuloplasty ring also includes an internal anchor member located at least partially within the outer hollow member. The internal anchor member includes a plurality of anchors configured to attach the annuloplasty ring to tissue of a heart valve annulus. The internal anchor member is configured to move the plurality of anchors with respect to a plurality of windows in the outer hollow member to selectively deploy the plurality of anchors through the respective windows. | 05-17-2012 |
20120197392 | ADJUSTABLE ANNULOPLASTY RING WITH SUBCUTANEOUS ACTIVATION PORT - Annuloplasty rings are employed to treat heart valve defects, such as regurgitation. Synching the heart tissue to the ring restores the valve opening to its approximate original size and operating efficiency. Adjustable annuloplasty rings allow for a proper degree of synching both during open heart surgery and over the patient's lifetime. A subcutaneous port may be coupled to an adjustable annuloplasty ring such that an external activation energy generator can be used to heat the adjustable annuloplasty ring and thereby adjust the size of the annuloplasty ring. | 08-02-2012 |
20120289977 | MITRAL VALVE REPAIR SYSTEM AND METHOD FOR USE - The present invention is directed to a method of securing suture within a patient. The method comprises advancing suture material into the patient, passing a portion of the suture material through tissue of the patient, and advancing a fastener catheter and a suture fastener along the suture material. The fastener catheter includes a catheter main body and a handle. The suture fastener has a generally cylindrical body formed of a shape memory material and a suture fastener inner lumen. The suture fastener has at least one engagement tab biased to extend at least partially into the suture fastener inner lumen to engage against and secure one or more lines of suture passing through the suture fastener. | 11-15-2012 |
20120310330 | PERCUTANEOUS TRANSCATHETER REPAIR OF HEART VALVES VIA TRANS-APICAL ACCESS - Apparatus, systems, and methods are provided for repairing heart valves through percutaneous transcatheter delivery and fixation of annuloplasty rings to heart valves via a trans-apical approach to accessing the heart. A guiding sheath may be introduced into a ventricle of the heart through an access site at an apex of the heart. A distal end of the guiding sheath can be positioned retrograde through the target valve. An annuloplasty ring arranged in a compressed delivery geometry is advanced through the guiding sheath and into a distal portion of the guiding sheath positioned within the atrium of the heart. The distal end of the guiding sheath is retracted, thereby exposing the annuloplasty ring. The annuloplasty ring may be expanded from the delivery geometry to an operable geometry. Anchors on the annuloplasty ring may be deployed to press into and engage tissue of the annulus of the target valve. | 12-06-2012 |
20130126012 | SYSTEMS AND METHODS FOR PUNCTURE CLOSURE - Systems, apparatuses and methods are provided for use in closing punctures in vessel walls. An apparatus may have various combinations of an anchoring device, a positioning device and a heating element for closing a puncture within a vessel wall. An anchoring device may be a balloon, an expansible cage, a wire operated T-anchor, and/or a floating anchor. A positioning device may be a balloon, a sponge, and/or an expansible cage. A heating element may be flexible or rigid and preferably provides heat to target tissue through conduction and convection. A heating element may be flat-ended or dome-shaped. The heating element and anchoring device may be positioned a fixed distance apart to sandwich tissue between the heating element and the anchoring device. The heating element may operate in multiple stages. An initial stage may non-permanently adhere the heating element to the tissue and the subsequent stage may close the puncture. | 05-23-2013 |
20130289718 | PERCUTANEOUS TRANSCATHETER REPAIR OF HEART VALVES - Apparatus, systems, and methods are provided for repairing heart valves through percutaneous transcatheter delivery and fixation of annuloplasty rings to heart valves. An annuloplasty ring includes an outer hollow member including a plurality of segments. Adjacent segments cooperate with one another to change the outer hollow member from an elongate insertion geometry to an annular operable geometry. The annuloplasty ring also includes an internal anchor member located at least partially within the outer hollow member. The internal anchor member includes a plurality of anchors configured to attach the annuloplasty ring to tissue of a heart valve annulus. The internal anchor member is configured to move the plurality of anchors with respect to a plurality of windows in the outer hollow member to selectively deploy the plurality of anchors through the respective windows. | 10-31-2013 |
20130304197 | CARDIAC VALVE MODIFICATION DEVICE - In an aspect, there is a prosthetic valve modification device adapted for endovascular delivery to a cardiac valve. The valve includes first and second support elements each having a collapsed delivery configuration and a deployed configuration. There are at least two bridging members extending from the first support element to the second support element, the bridging members having a delivery configuration and a deployed configuration. The bridging members either extend radially inward from the first and second support elements in the deployed configuration or are entirely straight and devoid of any visible curvature when in said deployed configuration. | 11-14-2013 |
20140005778 | CARDIAC VALVE SUPPORT STRUCTURE | 01-02-2014 |
20140200662 | ANCHORING ELEMENTS FOR INTRACARDIAC DEVICES - An intracardiac device comprising a ring-shaped body and one or more anchoring or stabilizing elements attached to said body, said elements being selected from the group consisting of levered anchoring arms, elongate anchoring arms, and lateral extension elements, wherein said device is able to move between two conformations, a collapsed conformation suitable for insertion into a delivery catheter, and an open conformation, suitable for implantation at a cardiac valve annulus. | 07-17-2014 |
20150094802 | SINGLE-RING CARDIAC VALVE SUPPORT - The present invention is primarily directed a prosthetic cardiac valve support device adapted for endovascular delivery to a cardiac valve, comprising a single ring-shaped support element having an inner diameter and an outer diameter, wherein said support element has an outer perimeter that is entirely rigid, wherein said support element is fitted with one or more intra-ventricular and/or intra-atrial stabilizing elements, and wherein said support element has a collapsed delivery configuration and a deployed configuration. | 04-02-2015 |
20150133905 | Plaque Stabilization Using Cryoenergy - There is provided a method of supplying cryoenergy to a plaque within a blood vessel. The method comprises expanding an expandable membrane of a catheter apparatus with a pressure of less than 5 ATM (507 kPa), the catheter apparatus having been placed in thermal contact with the plaque within the blood vessel. The method also comprises establishing a temperature of between +15° C. (288K) and −35° C. (238K) at an interface of the expandable membrane and the blood vessel. A system and catheter apparatus are also provided. | 05-14-2015 |
20160000564 | DELIVERY SYSTEMS FOR CARDIAC VALVE SUPPORT DEVICES - The present device provides a delivery device ( | 01-07-2016 |
20160106539 | CARDIAC VALVE SUPPORT DEVICE FITTED WITH VALVE LEAFLETS - The present invention provides a cardiac valve support device adapted for endovascular delivery to a cardiac valve, wherein said support device comprises either a single support element with valve leaflets connected thereto or two interconnected support elements having valve leaflets connected to one of said two elements. The invention further encompasses a two-stage method for implanting a replacement cardiac valve, wherein the first stage comprises delivering a valve support device fitted with one or more valve leaflets to a location near a subject's cardiac valve, such that said valve leaflets fulfill the function previously fulfilled by the native valve. | 04-21-2016 |
Patent application number | Description | Published |
20140040671 | SECURING CRASH DUMP FILES - In a computer storage system, crash dump files are secured without power fencing in a cluster of a plurality of nodes connected to a storage system. Upon an occurrence of a panic of a crashing node and prior to receiving a panic message of the crashing node by a surviving node loading, in the cluster, a capturing node to become active, prior to a totem token being declared lost by the surviving node, for capturing the crash dump files of the crashing node, while manipulating the surviving node to continue to operate under the assumption the power fencing was performed on the crashing node. | 02-06-2014 |
20140089724 | SECURING CRASH DUMP FILES - In a computer storage system, crash dump files are secured without power fencing in a cluster of a plurality of nodes connected to a storage system. Upon an occurrence of a panic of a crashing node and prior to receiving a panic message of the crashing node by a surviving node loading, in the cluster, a capturing node to become active, prior to a totem token being declared lost by the surviving node, for capturing the crash dump files of the crashing node, while manipulating the surviving node to continue to operate under the assumption the power fencing was performed on the crashing node. | 03-27-2014 |
20150186204 | SECURING CRASH DUMP FILES - In a computer storage system, crash dump files are secured without power fencing in a cluster of a plurality of nodes connected to a storage system. Upon an occurrence of a panic of a crashing node and prior to receiving a panic message of the crashing node by a surviving node loading, in the cluster, a capturing node to become active, prior to a totem token being declared lost by the surviving node, for capturing the crash dump files of the crashing node, while restricting the capturing node from gaining access to the storage system for preventing unsynchronized access to the storage system in order to prevent data corruption. | 07-02-2015 |