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Bu, US

Dongsheng Bu, Piscataway, NJ US

Patent application numberDescriptionPublished
20090004108Smmr (Small Molecule Metabolite Reporters) For Use As In Vivo Glucose Biosensors - Small Molecule Metabolite Reporters (SMMRs) for use as in vivo glucose biosensors, sensor compositions, and methods of use, are described. The SMMRs include boronic acid-containing xanthene, coumarin, carbostyril and phenalene-based small molecules which are used for monitoring glucose in vivo, advantageously on the skin.01-01-2009

Fanping Bu, Foster City, CA US

Patent application numberDescriptionPublished
20110010005SYSTEM FOR ASSOCIATING INVENTORY WITH HANDLING EQUIPMENT IN SHIPPING CONTAINER YARD INVENTORY TRANSACTIONS - A system is provided to associate containers with handling equipment (HE) in a container storage facility. In the system an operation detector, such as a twistlock sensor that indicates when a container is picked up or dropped off, is installed on a first HE which is a piece of container handling equipment (CHE) that can lift the container. An event detector, such as a vibration sensor or distance measuring radar, is further installed on a second HE that is a tractor with an attached chassis for receiving and transporting a container. The event detector indicates when a container-operation-related event, such as a container pick up or drop off, occurred on the tractor chassis. The two detectors (operation and event) are used by a processor to associate the container with either the CHE or the tractor. The operation and event detectors can further be used in conjunction with position sensors such as a GPS sensor to accurately determine the position of the tractor and the CHE in a container yard. When the position sensors degrade in performance, an additional motion detector such as a speed sensor can be used to determine the tractor's distance from the CHE to locate an appropriate tractor involved in the operation.01-13-2011
20120089320METHOD OF AUTOMATIC POSITIONING FOR LOADING AND UNLOADING OF CONTAINER SHIPS IN CONTAINER TERMINALS - A method is provided for automatically locating a container in a stowage location of a container ship for loading and unloading of the container ship in container terminals. The method includes the following steps: obtaining the position information of the container ship from container ship positioning units, obtaining the position information of the container from container positioning units when the container is in its stowage location, and determining the stowage location of the container in the container ship by first computing a relative position of the container in the container ship based on both the position information of the container ship and the position information of the container and then correlating the relative position with a stowage plan of the container ship.04-12-2012

Guojun Bu, Chesterfield, MO US

Patent application numberDescriptionPublished
20080227698OLIGOPEPTIDES FOR TREATMENT OF OSTEOPOROSIS AND OTHER BONE DISEASES AND METHODS THEREOF - Oligopeptides which can be used to treat bone disease such as osteoporosis are disclosed. Further disclosed are methods of treating bone disease such as osteoporosis. These methods include administration of a polypeptide encoded by the Mesd gene, or an oligopeptide comprising a contiguous subsequence of a Mesd polypeptide.09-18-2008
20100055712Oligopeptides for treatment of osteoporosis and other bone diseases and methods therefor - Methods of identifying compounds for treating Alzheimer's disease are disclosed. These methods comprise a) forming an in vitro mixture comprising i) cells expressing LDL receptor related protein 1 (LRP1), ii) an LRP1 ligand comprising a label, and iii) a candidate compound; and b) determining quantity of the label incorporated by the cells, whereby a candidate compound is deemed effective for treating Alzheimer's disease if the quantity of label incorporated by the cells exceeds that of a control in vitro mixture comprising cells expressing LRP1 and the LRP1 ligand, but not comprising the compound.03-04-2010
20100120685METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER - Oligopeptides which can be used to treat cancer are disclosed. Further disclosed are methods of treating cancer, including breast cancer, skin cancer, prostate cancer and multiple myeloma (MM). These methods include administration of a polypeptide encoded by the Mesd gene, or an oligopeptide comprising a contiguous subsequence of a Mesd polypeptide.05-13-2010

Jiankang Bu, Windham, ME US

Patent application numberDescriptionPublished
20100259996System and method for providing low cost high endurance low voltage electrically erasable programmable read only memory - A system and method are disclosed for increasing the reliability of a channel erase procedure in an electrically erasable programmable read only memory (EEPROM) memory cell. A memory cell of the present invention comprises a program gate, a control gate, and a floating gate that erase data using a channel erase procedure. An erase capacitor is coupled to the floating gate to provide a low voltage bias that decreases the voltage that is required to perform a Fowler-Nordheim erase process in the memory cell. The erase capacitor of the present invention is formed without adding a step in the manufacturing process of the memory cell. Memory cells of the present invention are low cost, high endurance, low voltage memory cells.10-14-2010
20100276740Method for fabricating higher quality thicker gate oxide in a non-volatile memory cell and associated circuits - A non-volatile memory cell includes a program transistor and a control capacitor. A portion of a substrate associated with the program transistor is exposed to multiple implantations (such as DNW, HiNWell, HiPWell, and P-well implantations). Similarly, a portion of the substrate associated with the control capacitor is exposed to multiple implantations (such as DNW, HiNWell, HiPWell, P-well, and N-well implantations). These portions of the substrate may have faster oxidation rates than other portions of the substrate, allowing a thicker front-end gate oxide to be formed over these portions of the substrate. In addition, a rapid thermal process anneal can be performed, which may reduce defects in the front-end gate oxide and increase its quality without having much impact on the oxide over the other portions of the substrate.11-04-2010
20110215419SYSTEM AND METHOD FOR IMPROVING CMOS COMPATIBLE NON VOLATILE MEMORY RETENTION RELIABILITY - A system and method is disclosed for improving complementary metal oxide semiconductor (CMOS) compatible non volatile memory (NVM) retention reliability in memory cells. A memory cell of the invention comprises a backend layer that reduces charge leakage from a floating gate of the memory cell. A first bottom portion of the backend layer is formed from a first layer of silicon oxynitride having a low value of defect/trap density. A second top portion of the backend layer is formed from a second layer of silicon oxynitride having a high value of defect/trap density. The first layer of silicon oxynitride inhibits electron transport and the second layer of silicon oxynitride protects CMOS devices from plasma induced damage.09-08-2011
20110287596SYSTEM AND METHOD FOR PROVIDING LOW VOLTAGE HIGH DENSITY MULTI-BIT STORAGE FLASH MEMORY - A system and method is disclosed for providing a low voltage high density multi-bit storage flash memory. A dual bit memory cell of the invention comprises a substrate having a common source, a first drain and first channel, and a second drain and a second channel. A common control gate is located above the source. A first floating gate and a second floating gate are located on opposite sides of the control gate. Each floating gate is formed with a sharp tip adjacent to the control gate and an upper curved surface that follows a contour of the surface of the control gate. The sharp tips of the floating gates efficiently discharge electrons into the control gate when the memory cell is erased. The curved surfaces increase capacitor coupling between the control gate and the floating gates.11-24-2011

Lei Bu, Malden, MA US

Patent application numberDescriptionPublished
20120135051GENERATION OF VASCULARIZED HUMAN HEART TISSUE AND USES THEREOF - The present invention relates to the generation of vascularized human heart tissue from human primordial Islet1-positive (ISL1+) progenitors, and more particularly the generation of vascularized human heart tissue from human primordial Islet1+ cardiovascular stem cells which are positive for markers ISL1+/NKX2.5−/KDR−. One aspect of the invention relates to isolation of human ISL1+ primordial cells from human pluripotent cells, such as human ES cells or other human pluripotent stem cell sources, wherein the human ISL1+ primordial cells can differentiate into three different lineages; cardiomyocyte lineages, endothelial lineages and smooth muscle lineages. Another aspect relates to use and implantation of the human primordial ISL1+ progenitors into an animal model to generate human vascularized heart tissue, and more particularly, the production of an in vivo humanized model of vascular disease. One embodiment relates to the use of an in vivo humanized model of vascular disease as an assay, for example to assess drug toxicity and/or identify agents which increase and decrease coronary blood flow to the human vascularized heart tissue. Another embodiment relates to the therapeutic use of human primordial ISL1+ progenitors, for example, in one embodiment the invention provides methods for the treatment cardiovascular disorders and/or congenital heart disease in a subject comprising transplanting into subjects vascularized human heart tissue generated from human ISL1+ progenitors.05-31-2012

Lujia Bu, Holden, MA US

Patent application numberDescriptionPublished
20080226889Curable compositions - Curable compositions are disclosed. Also disclosed are optical media comprising said curable compositions when cured and methods of making such optical media.09-18-2008
20100220583Optical data storage media and methods of formation - Provided are methods of forming multi-layered optical data storage media which include a high-density data layer, as well as multi-layered optical data storage media that can be formed by such methods.09-02-2010
20120129332METHOD FOR FORMING METAL CONTACTS - Methods of forming metal contacts with metal inks in the manufacture of photovoltaic devices are disclosed. The metal inks are selectively deposited on semiconductor coatings by inkjet and aerosol apparatus. The composite is heated to selective temperatures where the metal inks burn through the coating to form an electrical contact with the semiconductor. Metal layers are then deposited on the electrical contacts by light induced or light assisted plating.05-24-2012

Patent applications by Lujia Bu, Holden, MA US

Mark Bu, Aliso Viejo, CA US

Patent application numberDescriptionPublished
20100220282EYEGLASS COMPONENT MOUNTING SYSTEM - An eyeglass component mounting system is provided that can comprise a frame and at least a first ear stem. The first ear stem extends rearwardly from the frame and defines an anterior end and a posterior end. The anterior end of the first ear stem can be hingedly coupled to the frame such that the first ear stem can be pivotably movable between a stowed position and a deployed position. The first ear stem can comprise a mounting area configured to receive an eyewear component thereon such that the eyewear component can be removed or seated onto the mounting area when the first ear stem is in the stowed position and such that the eyewear component is retained on the mounting area when the first ear stem is in the deployed position.09-02-2010
20110102733EYEGLASS COMPONENT MOUNTING SYSTEM - An eyeglass component mounting system is provided that can comprise a frame and at least a first ear stem. The first ear stem extends rearwardly from the frame and defines an anterior end and a posterior end. The anterior end of the first ear stem can be hingedly coupled to the frame such that the first ear stem can be pivotably movable between a stowed position and a deployed position. The first ear stem can comprise a mounting area configured to receive an eyewear component thereon such that the eyewear component can be removed or seated onto the mounting area when the first ear stem is in the stowed position and such that the eyewear component is retained on the mounting area when the first ear stem is in the deployed position.05-05-2011

Vincent Bu, Woburn, MA US

Patent application numberDescriptionPublished
20100329666THERMAL CHIRP COMPENSATION IN A CHIRP MANAGED LASER - Thermal chirp compensation in a chirp managed laser. In one example embodiment, a method for thermal chirp compensation in a chirp managed laser (CML) includes several acts. First, a first bias condition and temperature is selected. Next, a first thermal chirp compensation signal is generated. Then, the laser is driven by biasing a first input drive signal with the first thermal chirp compensation signal. Next, a second bias condition and temperature is selected. Then, a second thermal chirp compensation signal is generated. Finally, the laser is driven by biasing a second input drive signal with the second thermal chirp compensation signal.12-30-2010