| Patent application number | Description | Published |
| 20080292638 | Tgf-Beta Binding Antibodies - The present invention provides very high affinity antibodies, or antigen-binding fragments thereof, that neutralize mature human TGF-β1, TGF-β2, and TGF-β3. The antibodies of the invention are useful for treating cell proliferative disorders in a mammal. | 11-27-2008 |
| 20090131638 | ANTI-MYOSTATIN ANTIBODIES - Anti-myostatin antibodies are identified that are characterized as having high affinity and may be chimeric, humanized or fully human antibodies, immunoconjugates of the antibodies or antigen-binding fragments thereof. The antibodies of the invention are useful for increasing muscle mass, increasing bone density, or for the treatment of various disorders in mammalian and avian species. | 05-21-2009 |
| 20090155285 | TGF-BETA BINDING ANTIBODIES - The present invention provides very high affinity antibodies, or antigen-binding fragments thereof, that neutralize mature human TGF-β1, TGF-β2, and TGF-β3. The antibodies of the invention are useful for treating cell proliferative disorders in a mammal. | 06-18-2009 |
| 20100087368 | TREATING ACUTE RENAL FAILURE WITH SOLUBLE THROMBOMODULIN VARIANTS - The present invention provides a method for preventing and/or treating subjects with acute renal failure caused by a variety of conditions. The method comprises administering to the subject soluble thrombomodulin which does not activate Protein C. In conjunction with standard of care, soluble thrombomodulin that does not activate Protein C will prevent or reduce acute kidney injury and subsequent morbidity and mortality. | 04-08-2010 |
| 20100136021 | TGF-BETA BINDING ANTIBODIES - The present invention provides very high affinity antibodies, or antigen-binding fragments thereof, that neutralize mature human TGF-β1, TGF-β2, and TGF-β3. The antibodies of the invention are useful for mating cell proliferative disorders in a mammal. | 06-03-2010 |