Patent application number | Description | Published |
20120283123 | Biomarkers for the Diagnosis of Kidney Graft Rejection - Methods are provided for determining a transplant category of a subject having a kidney graft. In practicing one aspect of the subject methods, the peptide signature of a non-invasive sample derived from the transplant subject (e.g., a urine sample) is used to determine the subject's transplant category (e.g., acute allograft rejection (AR), stable allograft (STA), BK virus nephropathy (BK), and the like). In other embodiments, a gene expression signature from a biopsy sample from the subject (e.g., mRNA level) is used to determine the subject's transplant category. In certain embodiments both a peptide signature and a gene expression signature are used. Also provided are compositions, systems, kits and computer program products that find use in practicing the subject methods. | 11-08-2012 |
20130052665 | METHODS FOR DIAGNOSIS OF SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS - Methods for diagnosis of systemic juvenile idiopathic arthritis (SJIA) are disclosed. In particular, the invention relates to the use of biomarkers for diagnosis of SJIA, which can be used to distinguish SJIA from other inflammatory diseases, including infectious illness, acute febrile illness, Kawasaki disease, and similar juvenile idiopathic arthritis (JIA) disease subtypes, and to predict inflammatory flares in SJIA patients in advance of clinical symptoms. | 02-28-2013 |
20130316921 | METHODS FOR DIAGNOSIS OF KAWASAKI DISEASE - Methods for diagnosis of Kawasaki disease (KD) are disclosed. In particular, the invention relates to the use of biomarkers for aiding diagnosis, prognosis, and treatment of KD, and more specifically to biomarkers that can be used to distinguish KD from other inflammatory diseases, including infectious illness and acute febrile illness. | 11-28-2013 |
20140162370 | URINE BIOMARKERS FOR NECROTIZING ENTEROCOLITIS AND SEPSIS - Aspects of the invention include methods, compositions, and kits for diagnosing Necrotizing Enterocolitis (NEC), for diagnosing sepsis, for providing a prognosis for a patient with NEC, and for predicting responsiveness of a patient with NEC to medical intervention. These methods find use in a number of applications, such as diagnosing and treating infants who are suspected of having NEC, intestinal perforation (IP), or sepsis. | 06-12-2014 |
20150099655 | Methods and Compositions for Providing a Preeclampsia Assessment - Preeclampsia markers, preeclampsia marker panels, and methods for obtaining a preeclampsia marker level representation for a sample are provided. These compositions and methods find use in a number of applications, including, for example, diagnosing preeclampsia, prognosing a preeclampsia, monitoring a subject with preeclampsia, and determining a treatment for preeclampsia. In addition, systems, devices and kits thereof that find use in practicing the subject methods are provided. | 04-09-2015 |
20150177244 | PARALLEL ANALYSIS OF SERUM EPCAM AND MMP7 TO DISCRIMINATE SEPSIS, NECROTIZING ENTEROCOLITIS AND NORMAL CONTROL PATIENTS - Methods and compositions are provided for making a necrotizing enterocolitis (NEC) or sepsis assessment of an individual. Aspects of the methods include detecting a biomarker or panel of biomarkers selected from MMP7, EpCAM, and CRP. In addition, reagents, devices, systems and kits thereof that find use in practicing the subject methods are provided. | 06-25-2015 |
20150285816 | SNP FOR PREDICTING EFFECTIVENESS OF PRETERM BIRTH DIAGNOSTIC TEST - Methods and compositions for providing a preterm birth prognosis for a pregnant individual, monitoring a pregnant individual for increased risked of preterm birth, or making a treatment decision for a pregnant individual predicting preterm birth are provided. Aspects include selecting the appropriate ITIH4 preterm peptide biomarker to detect to make a preterm birth prediction. These methods and compositions find use in providing a preterm birth prognosis for a pregnant individual. | 10-08-2015 |
20150377905 | METHODS FOR DIAGNOSIS OF KAWASAKI DISEASE - Methods for diagnosis of Kawasaki disease (KD) are disclosed. In particular, the invention relates to the use of biomarkers for aiding diagnosis, prognosis, and treatment of KD, and to a panel of biomarkers that can be used to distinguish KD from febrile illness. | 12-31-2015 |