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Bruce Marx, Ojai US

Bruce Marx, Ojai, CA US

Patent application numberDescriptionPublished
20080249395METHOD AND APPARATUS FOR CONTROLLING CATHETER POSITIONING AND ORIENTATION - A method and apparatus for detecting position and orientation of catheter distal magnetic element end while moving in a patient's heart is described. The apparatus includes magnetic sensors for to detect the magnetic field of a generated by the catheter tip. Each sensor transmits the field magnitude and direction to a detection unit, which filters the signals and removes other field sources, such as generated by CGCI coils and external medical hardware. The method allows the measurements of magnitude corresponding to the catheter tip distance from the sensor and the orientation of the field showing the magnetic tip orientation. Since the tip's magnetic field is not necessarily symmetric, the position and orientation computation technique are not independent of each other. Hence, an iterative calculation is used to converge to a solution. The method of determining tip position is calculated by triangulation from each sensor. In one embodiment, the tip orientation is calculated by an intersecting-planes algorithm. The orientation is used to adjust the distances from each sensor, and the process is repeated until convergence for both position and orientation is achieved. The resultant value provides the actual catheter tip position and orientation (AP). The actual position is further filtered by synchronizing the AP measurements with the QRS signal of the heart, allowing the operator and CGCI controller to view the organ as a static object.10-09-2008
20090253985APPARATUS AND METHOD FOR LORENTZ-ACTIVE SHEATH DISPLAY AND CONTROL OF SURGICAL TOOLS - The Lorentz-Active Sheath (LAS) serves as a conduit for other medical devices such as catheters, balloons, biopsy needles, etc. The sheath is inserted through a vein or other body orifice and is guided into the area of the patient where the operation is to be performed. The position and orientation of the LAS is tracked via an industry standard position detection system which senses electrical signals that are emitted from several electrodes coupled to the LAS. The signals received from the LAS are used to calculate an accurate and reliable assessment of the actual position of the LAS within the patient. The electrode signals also serve to create a reference frame which is then used to act as a motion compensation filter and fiducial alignment system for the movement of the LAS-hosted medical tool.10-08-2009
20090275828METHOD AND APPARATUS FOR CREATING A HIGH RESOLUTION MAP OF THE ELECTRICAL AND MECHANICAL PROPERTIES OF THE HEART - A system method that tracks one or more points on the surface of a cardiac tissue throughout a cardiac cycle and collect various types of data points which are then subsequently used to generate a corresponding model of the tissue and display the model as a 3D color coded image is described. In one embodiment, the system determines the position and orientation of a distal tip of a catheter, manipulates the catheter tip so as to maintain constant contact between the tip and a region of cardiac tissue using the impedance method, acquires positional and electrical data of the tip-tissue configuration through an entire heartbeat cycle, repeats the measurements as many times as needed in different tissue regions, and forms a 3D color coded map displaying various mechanical and electrical properties of the heart using the acquired data.11-05-2009
20090318902Magnetic Breather Pump and a Method for Treating a Brain Tumor Using the Same - A magnetically controlled pump is implanted into the brain of a patient and delivers a plurality of medicating agents at a controlled rate corresponding to the specific needs of the patient. The current invention comprises a flexible double walled pouch that is formed from two layers of polymer. The pouch is alternately expanded and contracting by magnetic solenoid. When contracted, a medicating agent is pushed out of the pouch through a plurality of needles. When the pouch is expanded, surrounding cerebral fluid is drawn into the space between the double walls of the pouch from which it is drawn through a catheter to an analyzer. Cerebral fluid drawn from the patient is analyzed. The operation of the apparatus and hence the treatment is remotely controlled based on these measurements and displayed through an external controller.12-24-2009
20090318903Magnetic Breather Pump and a Method for Treating a Brain Tumor Using the Same - A magnetically controlled pump is implanted into the brain of a patient and delivers a plurality of medicating agents at a controlled rate corresponding to the specific needs of the patient. The current invention comprises a flexible double walled pouch that is formed from two layers of polymer. The pouch is alternately expanded and contracting by magnetic solenoid. When contracted, a medicating agent is pushed out of the pouch through a plurality of needles. When the pouch is expanded, surrounding cerebral fluid is drawn into the space between the double walls of the pouch from which it is drawn through a catheter to an analyzer. Cerebral fluid drawn from the patient is analyzed. The operation of the apparatus and hence the treatment is remotely controlled based on these measurements and displayed through an external controller.12-24-2009
20100130854SYSTEM AND METHOD FOR A CATHETER IMPEDANCE SEEKING DEVICE - A tissue-contact seeking method and apparatus is described that enhances catheter position detection and control systems in making and maintaining continuous tissue contact in a highly dynamic frame, such as under the rigors of cardiac motion. Tissue-seeking logical routines use a tissue contact sensing system to advance a catheter to relatively continuous tissue contact, or detect obstacles, in cooperation with the catheter position detection and control systems. Additional logical routines are capable of optimizing the contact direction of the catheter tip by controlling the rotation angle and chamber position of the introducer.05-27-2010
20100160737BRAIN RETRACTOR APPARATUS FOR MEASURING AND PREDICTING ELECTROPHYSIOLOGICAL PARAMETERS - Described is a surgical system for monitoring a patient's condition during surgery. One aspect is a non-contact EEG sensor. The non-contact EEG sensor can be used to predict the onset of physiological disorders. Another aspect includes the use of a plurality of pressure sensors to determine the pressure applied by retractors on the patient, including the brain and other organs.06-24-2010
20100305429SYSTEM AND METHOD FOR USING TISSUE CONTACT INFORMATION IN AN AUTOMATED MAPPING OF CARDIAC CHAMBERS EMPLOYING MAGNETICLY SHAPED FIELDS - The invention relates to a method for using tissue contact technology to optimize automated cardiac chamber mapping algorithms to both speed up the mapping process and guarantee the definition of the actual chamber limits. The invention further comprises a method for conveying tissue type information to such automatic mapping algorithms so as to allow them to adapt their point collection density within areas of particular interest. The method is enhanced by the use of a magnetic chamber that employs electromagnetic coils configured as a waveguide that radiate magnetic fields by shaping the necessary flux density axis on and around the catheter distal tip so as to push, pull and rotate the tip on demand and as defined by such automatic mapping algorithms.12-02-2010
20110092808METHOD FOR ACQUIRING HIGH DENSITY MAPPING DATA WITH A CATHETER GUIDANCE SYSTEM - The invention is a method of rotating a catheter while it is manually guided in order to increase the volume of space it passes through during a geometric mapping procedure as to provide a higher and more uniform location data point cloud density in a volumetric mapping system.04-21-2011
20110092950Metronomic Convection Enhanced Delivery of Intrathecal Chemotherapy Using an Implanted Magnetic Breather Pump (MBP) for Leptomeningeal Carcinomatosis - A magnetically controlled pump is implanted into the cerebrospinal fluid of a patient and delivers a plurality of medicating agents at a controlled rate corresponding to the specific needs of the patient. The current invention comprises a flexible double walled lumen, intratumoral catheter which will be implanted. Spinal fluid drawn from the patient is analyzed. Medication is delivered on a continuous metronomic basis into the CSF via an internalized pump. CSF is removed and analyzed for VEGF and other cytokines via spectrophotometer analysis or a lab on a chip. The operation of the apparatus and hence the treatment is remotely controlled based on these measurements and displayed through an external controller.04-21-2011
20110092960ENHANCED METHOD FOR DELIVERING BEVACIZUMAB (AVASTIN) INTO A BRAIN TUMOR USING AN IMPLANTED MAGNETIC BREATHER PUMP - A magnetically controlled pump is implanted into the brain of a patient and delivers a plurality of medicating agents mixed with Avastin at a controlled rate corresponding to the specific needs of the patient. The current invention comprises a flexible double walled pouch that is formed from two layers of polymer. The pouch is alternately expanded and contracting by magnetic solenoid. When contracted, the medicating agent Avastin is pushed out of the pouch through a plurality of needles. When the pouch is expanded, surrounding cerebral fluid is drawn into the space between the double walls of the pouch from which it is drawn through a catheter to an analyzer. In cases where a tumor resection is not performed, an intratumoral catheter will be implanted. Cerebral fluid drawn from the patient is analyzed. The operation of the apparatus and hence the treatment is remotely controlled based on these measurements and displayed through an external controller.04-21-2011
20110112396SYSTEM AND METHOD FOR TARGETING CATHETER ELECTRODES - A system and method is described for a catheter guidance system which allows an operator to use a mapping catheter to specify tissue target locations for the automatic guidance of a second therapeutic catheter. The operator places a mapping catheter at a desired location, and commands the catheter guidance system by either selecting a point on that catheter or one of the catheter electrode electrocardiograms. The operator may target the selected dynamic location, or tissue contact beyond that location on a specific side of the mapping catheter.05-12-2011

Patent applications by Bruce Marx, Ojai, CA US