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Bruce Hopenfeld

Bruce Hopenfeld, Salt Lake City, UT US

Patent application numberDescriptionPublished
20090048528System and methods for detecting ischemia with a limited extracardiac lead set - Disclosed is a system for detecting pathophysiological cardiac conditions from a reduced number of extracardiac leads. A right side lead measures the electrical signal between the middle superior chest region over the heart and inferior right torso position. A left side lead measures the electrical signal between the left precordial chest region and an inferior left lateral or posterior torso position. The lead montage is preferably chosen so that, regardless of patient position (e.g. supine, upright), negative ST segments and/or T waves are used to detect right coronary or left circumflex ischemia. Also, in these positions, reduced slope of the final deflection in the QRS can be used to detect these types of ischemia. To detect transmural ischemia, the system examines changes in QRS slopes, ST segment, T wave and the difference between the J point and the PQ potentials. In addition, for transmural ischemia associated with the left anterior descending artery, a proxy for the propagation time across the front of the heart is examined by comparing QRS features of the right side lead with QRS features of the left side lead. Histogram profiles, trends, and statistical summaries, especially running averages, of all of the above mentioned features, corrected for heart rate, are maintained.02-19-2009
20090076403Waveform feature value averaging system and methods for the detection of cardiac events - Disclosed is a system for detecting pathophysiological cardiac conditions. The system comprises a diagnostic device that contains electronic circuitry that can detect a cardiac event such as an acute ischemia. The cardiac diagnostic device receives electrical signals from subcutaneous or body surface sensors. The cardiac diagnostic device includes a processor that computes QRS onset and offset points and fiducial points associated with T and U waves. The processor than baseline corrects the original signal/waveform by fitting a polynomial function to QRS offset points, and subtracting this function from the original waveform. Based on the baseline adjusted signal and/or the above mentioned fiducial points, the processor then computes averages of various waveform feature values, including a QRS measure sensitive to QRS curvature, T wave timing measures, ST segment deviation (difference between signal amplitudes at QRS offset and onset and/or minimum amplitude between QRS offset and peak T wave); and T/U wave amplitudes. These averages are computed by exponential averaging. From the exponential averages, the processor computes an average of the change in the averages over time. Based on the averages and the change in the averages, the processor applies an ischemia test to determine a likelihood of ischemia.03-19-2009
20090076404System and methods for analyzing QRS curvature to detect cardiac events - Disclosed is a system for detecting pathophysiological cardiac conditions. The system comprises a diagnostic device that contains electronic circuitry that can detect a cardiac event such as an acute ischemia. The cardiac diagnostic device receives electrical signals from subcutaneous or body surface sensors. The cardiac diagnostic device includes a processor that computes a measure of QRS curvature and applies an ischemia test based on the measure of QRS curvature to determine a likelihood of ischemia.03-19-2009
20090216144Hopping methods for the detection of QRS onset and offset - Disclosed are systems and methods for detecting the QRS portion of an electrocardiogram and also for detect QRS onset/offset points. QRS complexes are identified by testing selected waveform samples to determine if they are in a high curvature region. If a region passes the high curvature test, a verification test is applied to adjacent samples to confirm that the region is within a QRS complex. The search for a QRS onset point begins at an adaptive distance from this region. The curvature of selected regions ahead in the search direction is examined. The search moves past all such high curvature regions. The onset point is then located by searching for a region that is “flat” in either of two senses. First, a region may be locally flat (i.e. small first derivative) in an absolute sense. Second, a region is flat in a relative that further movement away from the interior of the QRS (e.g. toward “earlier” samples) does not result in a significant change in the value of the first derivative. The search is performed by hopping through the waveform samples. Once an onset point is located, the search for an offset point proceeds in a similar manner from a starting point that is an adaptively determined distance from the onset point.08-27-2009
20100241017SYSTEM AND METHODS FOR THE SELECTIVE UPDATING OF HEART SIGNAL PARAMETER TIME SERIES - A heart rate monitor is disclosed. The monitor generates an ST deviation time series by employing a recursive filter that is preferably an exponential average filter whose output is a weighted sum of the then existing ST time series value and current ST deviation values of analyzable beats, seats are detected in segments of data. ST deviation is measured for analyzable beats. The ST deviation time series is updated only if certain criteria are met. A first criterion for updating the time series is that at least half of the beats within a segment must be normal sinus rhythm beats: A second criterion for updating the time series is that (i) the average RR interval of the segment is between ¾ and 1.5 times the average RR interval of the previous segment; or (ii) both (a) the number of abnormal beats in the current segment is less than 2, and (b) the number of premature ventricular contractions within the current segment is less than 2.09-23-2010
20110040199Heart rate correction system and methods for the detection of cardiac events - A device for detecting a cardiac event is disclosed. Detection of an event is based on a test applied to a parameter whose value varies according to heart rate. Both the parameter value and heart rate (RR interval) are filtered with an exponential average filter. From these filtered values, the average change in the parameter and the RR interval are also computed with an exponential average filter. Before computing the average change in the parameter, large changes in the parameter over short times, which may be caused by body position shifts, are attenuated are removed, so that the average change represents an average of small/smooth changes in the parameter's value that are characteristic of acute ischemia, one of the cardiac events that may be detected. The test to detect the cardiac event depends on the heart rate, the difference between the parameter's value and its upper and lower normal values, and its average change over time, adjusted for heart rate changes. The upper and lower normal parameter values as a function of heart rate are determined from long term stored data of the filtered RR values and parameter values. Hysteeresis related data and transitory deviations from normal (e.g. vasospasm related data) are excluded from the computation of normal upper and lower parameter bounds.02-17-2011
20110125041ISCHEMIA MONITORING SYSTEM FOR PATIENTS HAVING PERIODS OF LEFT BUNDLE BRANCH BLOCK - A device for detecting cardiac ischemia is disclosed. The device includes a processor that is configured to distinguish between two different heart beats types such as left bundle branch block beats and normal sinus beats. The processor applies different ischemia tests to the two different beat types, and generates alert when it detects ischemia.05-26-2011

Patent applications by Bruce Hopenfeld, Salt Lake City, UT US

Bruce Hopenfeld, Oceanport, NJ US

Patent application numberDescriptionPublished
20080208069System and methods of hierarchical cardiac event detection - A system for the detection of cardiac events occurring in a human patient is provided. At least two electrodes are included in the system for obtaining an electrical signal from a patient's heart. An electrical signal processor is electrically coupled to the electrodes for processing the electrical signal. An electrogram analysis scheme is described, according to which electrogram segments or individual beats are classified according to various features, and different cardiac event tests are applied based on this classification.08-28-2008
20090082682Methods and apparatus for detecting cardiac events based on heart rate sensitive parameters - A system for the detection of cardiac events occurring in a human patient is provided. At least two electrodes are included in the system for obtaining an electrical signal from a patient's heart. An electrical signal processor is electrically coupled to the electrodes for processing the electrical signal and applying tests to determine whether a cardiac event has occurred. When the processor detects some types of changes in heart rate, event detection is altered or suspended for a period of time.03-26-2009
20100087745Baseline processing for a cardiac event detection system - A system for the detection of cardiac events occurring in a human patient is provided. At least two electrodes are included in the system for obtaining an electrical signal from a patient's heart. An electrical signal processor is electrically coupled to the electrodes for processing the electrical signal and a patient alarm means is further provided and electrically coupled to the electrical signal processor. The electrical signal is acquired in the form of electrogram segments, which are categorized according to heart rate, ST segment shift and type heart rhythm (normal or abnormal). Baseline electrogram segments are tracked over time.04-08-2010

Patent applications by Bruce Hopenfeld, Oceanport, NJ US