| Patent application number | Description | Published |
|---|
| 20080306267 | METHOD FOR MAKING TETRABENAZINE COMPOUNDS - A method of preparing a tetrabenazine compound (TBZ compound) having structure I comprising the steps of reacting a nucleophilic alkenyl species with aldehyde compound II and oxidizing the resultant allylic alcohol to provide enone III. The protecting group P | 12-11-2008 |
| 20080306269 | INTERMEDIATES USEFUL FOR MAKING TETRABENAZINE COMPOUNDS - A method of preparing a tetrabenazine compound (TBZ compound) having structure I comprising the steps of reacting a nucleophilic alkenyl species with aldehyde compound II and oxidizing the resultant allylic alcohol to provide enone III. The protecting group P | 12-11-2008 |
| 20090110636 | FLUORINATED DIHYDROTETRABENAZINE ETHER IMAGING AGENTS AND PROBES - The present invention provides novel fluorinated ether compounds having structure I | 04-30-2009 |
| 20090111990 | INTERMEDIATES FOR FLUORINATED DIHYDROTETRABENAZINE ETHER IMAGING AGENTS AND PROBES - The present invention provides novel fluorophilic compounds having structure VI | 04-30-2009 |
| 20090142265 | ALPHA-FLUOROALKYL TETRABENAZINE AND DIHYDROTETRABENAZINE IMAGING AGENTS AND PROBES - The present invention provides novel alpha-fluoroalkyl compounds having structure I and the corresponding dihydrotetrabenazine compounds IV | 06-04-2009 |
| 20090142276 | ALPHA-FLUOROALKYL DIHYDROTETRABENAZINE IMAGING AGENTS AND PROBES - The present invention provides novel alpha-fluoroalkyl dihydrotetrabenazine compounds I | 06-04-2009 |
| 20090143587 | INTERMEDIATES FOR ALPHA-FLUOROALKYL TETRABENAZINE AND DIHYDROTETRABENAZINE IMAGING AGENTS AND PROBES - The present invention provides novel fluorophilic compounds having structure VII | 06-04-2009 |
| 20090149654 | INTERMEDIATES FOR FLUORINATED TETRABENAZINE CARBINOL COMPOUNDS IMAGING AGENTS AND PROBES - The present invention provides novel fluorophilic compounds having structure VII | 06-11-2009 |
| 20100310456 | IMAGING OF MYELIN BASIC PROTEIN - The present invention relates to methods for myelin basic protein detection comprises identifying a subject at risk of or diagnosed with a myelin-associated neuropathy, parenterally administering to the subject the agent, and determining myelination in the subject by detecting binding to myelin basic protein. Methods for the detection of myelin and a quantitative measurement of its local concentration in a sample using an agent with specific binding to myelin basic protein are also provided as is a kit containing the agent or its derivatives for use in detecting myelin basic protein | 12-09-2010 |
| 20100310457 | IMAGING OF MYELIN BASIC PROTEIN - The present invention relates to methods for myelin basic protein detection comprises identifying a subject at risk of or diagnosed with a myelin-associated neuropathy, parenterally administering to the subject the agent, and determining myelination in the subject by detecting binding to myelin basic protein. Methods for the detection of myelin and a quantitative measurement of its local concentration in a sample using an agent with specific binding to myelin basic protein are also provided as is a kit containing the agent or its derivatives for use in detecting myelin basic protein | 12-09-2010 |
| 20110142759 | AGENTS AND METHODS FOR THE IMAGING OF MYELIN BASIC PROTEIN - The present invention relates to agents capable of binding to myelin basic protein in a subject. Also provided are methods for the detection of myelin-associated neuropathy comprising identifying a subject at risk of or diagnosed with a myelin-associated neuropathy, administering to a subject an agent that binds specifically to myelin basic protein, and determining myelination in the subject by detecting the agent present in the subject. A kit containing the agent or its derivatives for use in detecting myelin basic protein is also provided. | 06-16-2011 |
