| Patent application number | Description | Published |
|---|
| 20110173169 | Methods To Perform Disk Writes In A Distributed Shared Disk System Needing Consistency Across Failures - Techniques are provided for managing caches in a system with multiple caches that may contain different copies of the same data item. Specifically, techniques are provided for coordinating the write-to-disk operations performed on such data items to ensure that older versions of the data item are not written over newer versions, and to reduce the amount of processing required to recover after a failure. Various approaches are provided in which a master is used to coordinate with the multiple caches to cause a data item to be written to persistent storage. Techniques are also provided for managing checkpoints associated with the caches, where the checkpoints are used to determine the position at which to begin processing recovery logs in the event of a failure. | 07-14-2011 |
| 20110179169 | Special Values In Oracle Clusterware Resource Profiles - A method and computer-readable storage representing resources in a cluster by a plurality of attribute-value pairs that together are part of a “resource profile,” in which each attribute-value pair defines all, or a portion of, a management policy that applies to the resource. A clusterware manager configures a resource according to the resource profile, and follows a resource profile syntax that specifies a runtime value for the resource in which an actual value is substituted at runtime. | 07-21-2011 |
| 20110295822 | Methods to Perform Disk Writes in a Distributed Shared Disk System Needing Consistency Across Failures - Techniques are provided for managing caches in a system with multiple caches that may contain different copies of the same data item. Specifically, techniques are provided for coordinating the write-to-disk operations performed on such data items to ensure that older versions of the data item are not written over newer versions, and to reduce the amount of processing required to recover after a failure. Various approaches are provided in which a master is used to coordinate with the multiple caches to cause a data item to be written to persistent storage. Techniques are also provided for transferring data items and locks associated with the data items from one node to another. | 12-01-2011 |
| Patent application number | Description | Published |
|---|
| 20090103967 | PEN RETENTION APPARATUS - A pen retention bracket for releasably securing a pen tether retracting reel therein is disclosed. The pen retention bracket includes four surfaces that define a rectangular cavity having four sides and a top opening and a bottom opening. A first protrusion and a second protrusion are disposed upon a first surface and extend from the first surface toward a second surface, a distance between the first protrusion and the second protrusion greater than a height of the pen tether retracting reel. The first surface is responsive to an application of force to the pen tether retracting reel to elastically deform and increase a depth between the second surface and at least one of the first protrusion and the second protrusion, thereby releasing the pen tether retracting reel via either of the top opening and the bottom opening. | 04-23-2009 |
| 20100096514 | BAG HOLDER - A bagging station is provided and includes a bagging station structure including a base and a supportive portion vertically supported on the base, a bag holder, configured to hold bag handles of a bag, to occupy and selectively move between a stowed position, at which the bag holder is stowed, and a plurality of presented positions, at which the bag holder is available for bag holding, and a coupling device to couple the bag holder to the supportive portion such that the bag holder is biased to remain in a currently occupied one of the stowed position or at least one of the presented positions. | 04-22-2010 |
| 20110312214 | TAMPER PREVENTION AND DETECTION APPARATUS FOR AN ELECTRONIC DEVICE - An apparatus for preventing and detecting tampering of an electronic device is provided. The apparatus may prevent and detect tampering occurring through an aperture in a casing of the electronic device where the aperture is configured for receiving a standoff that couples a communication cable to a communication port of the electronic device. Upon removal of the standoff, visual indicia of tampering may be provided. Additionally, a shield may block entry of the standoff into the aperture if the standoff is removed. | 12-22-2011 |
| Patent application number | Description | Published |
|---|
| 20090172955 | STRING TRIMMER HEAD - An improved string trimmer head is described. The trimmer head comprises a housing with a spool and spring assembly enclosed within the housing. The trimmer head further comprises a lid connected to the housing and a bump knob with a base and an intermediate member. The base of the bump knob is located inside the housing. The intermediate member extends outside the housing through the lid. The lid comprises an annulus which surrounds the base. The height of the annulus is greater than a maximum compressing distance of the spool when compressed by the bump knob. A segment of the intermediate member remains outside the lid when the spool is compressed. The bump knob further comprises a finger slot with an outer edge and a recessed portion. A bottom side of the outer edge is positioned farther away from the spool than the recessed portion. | 07-09-2009 |
| 20090266330 | Monolithic Block and Valve Train for a Four-Stroke Engine - A cylinder crankcase for a four-stroke engine is disclosed. The cylinder crankcase includes a cylinder head, cylinder block, and crankcase which are monolithic. A half-crank crankshaft bears in a crank arm, which is included in the crankcase. The cylinder crankcase includes a belt driven valve train and crank arm that includes a pocket containing a crank gear attached to the crankshaft for driving the belt. | 10-29-2009 |
| 20090308369 | Laminated Counterweight for Timing Control - A stratified two-stroke engine having a laminated counterweight is disclosed. The laminated counterweight includes a traditional counterweight portion and a laminate portion. The laminate portion has an approximately circular peripheral shape and at least one notch. In operation, the notch may be used to time the opening and closing of a mixture port or a transfer port. | 12-17-2009 |
| 20100006076 | Breather System for a Four Stroke Engine - A breather system for an engine used to vent combustion, or blow-by, gases. The breather system has an axial breather passage disposed within a camshaft of the engine. A radial opening is in fluid communication with the axial breather passage. A valve is positioned within the radial opening in order to prevent oil from entering the axial breather passage when the engine is not in operation. | 01-14-2010 |
| 20100145595 | SMALL ENGINE OPERATION COMPONENTS - A low pressure, low cost electronic fuel injection system ( | 06-10-2010 |
| Patent application number | Description | Published |
|---|
| 20090077982 | Advance instrumentation methods for pipes and conduits transporting cryogenic materials - A cryogenic material transfer system incorporates a pipe-in-pipe configuration with a nanoporous or microporous insulating layer filling the annulus between the inner and outer pipe. The insulating layer is of sufficient flexibility to absorb and expansion or contraction of the inner pipe due to the flow of cryogenic material therethrough. For longer transfer systems a bulkhead is provided between adjacent pipe joints. Intermediately of the pipe joints an additional bulkhead may be employed to provide additional sealing or water stops and for providing provide additional load transfer. A fiber optic sensor system is installed in the annuals between the inner and outer pipe. | 03-26-2009 |
| 20100229662 | Instrumentation and Monitoring System For Pipes and Conduits Transporting Cryogenic Materials - An instrumentation and monitoring system for a cryogenic material transfer system incorporates a pipe-in-pipe configuration with either a vacuum or a nanoporous or microporous insulating layer filling the annulus between the inner and outer pipe. The insulating layer is of sufficient flexibility to absorb the expansion or contraction of the inner pipe due to thermal effects from the flow of cryogenic material. The monitoring system typically includes a multitude of fiber optic sensors that measure leaks, temperature, pressure and strain. The invention includes the fiber optic sensors, conventional sensors, cabling, connectors/splice assembles, ingress/egress methods, ruggedization methods, data acquisition and analysis. | 09-16-2010 |
| 20110219866 | Apparatus to Monitor Flow Assurance Properties in Conduits - A combination of sensors are strategically placed along a pipeline to measure critical properties such as temperature and pressure of the flow product. The sensors are a combination of fiber optic sensing devices that are specifically designed to measure a range of properties within particular bandwidth, with a method to reduce light attenuation over the long pipeline distances. The pipeline is typically subsea and can range widely in diameter. In many cases the pipeline has a coating that acts as a barrier to the corrosive sea water and additional thermal barriers. | 09-15-2011 |
| Patent application number | Description | Published |
|---|
| 20100143948 | CHEMO-SENSITIVITY ASSAYS USING TUMOR CELLS EXHIBITING PERSISTENT PHENOTYPIC CHARACTERISTICS - The assays, methods, tools and systems discussed herein represent an improved and unified system for monitoring the progression of an individual patient malignancy. The assays, methods, tools and systems discussed herein represent an improved and unified system for monitoring and for identifying cellular and secreted markers, for screening cells to detect phenotypic and genotypic drift and for predicting chemotherapeutic response of patient tumor cells to at least one therapeutic agent. The assays, methods, tools and systems discussed herein also represent an improved and unified system for monitoring and for screening multiple pharmaceutical agents for efficacy and long term effect as to a specific patient. | 06-10-2010 |
| 20100216168 | METHODS FOR EVALUATING ANGIOGENIC POTENTIAL IN CULTURE - The present invention provides a method of evaluating the angiogenic potential of a tumor, and for predicting the efficacy of anti-angiogenic therapies on an individualized basis. The method of the invention involves preparing an angiogenic signature for malignant cells in culture by assaying for the presence or level of one or more angiogenesis-related factors selected from VEGF/VPF, IL8/CXCL8, TGF-β1, TGF-β2, TGF-β3, bFGF/FGF-2, EGF, PDGF-AA, PDGF-AA/BB, IP-10, and Flt-3 ligand. The angiogenic signature may be prepared from cultures maintained under normoxic and/or hypoxic environments. The invention may be used in conjunction with chemoresponse testing of anti-tumor agents, to predict or suggest a combination therapy for cancer patients. | 08-26-2010 |
| 20100311084 | METHODS FOR PREDICTING A PATIENT'S RESPONSE TO EGFR INHIBITORS - The present invention provides methods for individualizing chemotherapy for cancer treatment, and particularly for evaluating a patient's responsiveness to one or more epidermal growth factor receptor (EGFR) inhibitors prior to treatment with such agents. Particularly, the invention provides an in vitro chemoresponse assay for predicting a patient's response to a monoclonal EGFR antibody, such as cetuximab. The method generally comprises culturing malignant cells from a patient's specimen (e.g., biopsy specimen), contacting the cultured cells with a monoclonal EGFR antibody that is a candidate treatment for the patient, and evaluating the cultured cells for a response to the drug. In certain embodiments, monolayer(s) of malignant cells are cultured from explants prepared by mincing tumor tissue, and the cells of the monolayer are suspended and plated for chemosenstivity testing. The in vitro response to the drug as determined by the method of the invention is correlative with the patient's in vivo response upon receiving the monoclonal EGFR antibody during chemotherapeutic treatment (e.g., in combination with other standardized or individualized chemotherapeutic regimen). | 12-09-2010 |
| Patent application number | Description | Published |
|---|
| 20090286276 | METHODS FOR PREDICTING A PATIENT'S RESPONSE TO EGFR INHIBITORS - The present invention provides methods for individualizing chemotherapy for cancer treatment, and particularly for evaluating a patient's responsiveness to one or more epidermal growth factor receptor (EGFR) inhibitors prior to treatment with such agents. Particularly, the invention provides an in vitro chemoresponse assay for predicting a patient's response to an EGFR inhibitor, such as an EGFR tyrosine kinase inhibitor or a molecule targeting the extracellular domain of EGFR. The method generally comprises culturing malignant cells from a patient's specimen (e.g., biopsy specimen), contacting the cultured cells with an EGFR inhibitor that is a candidate treatment for the patient, and evaluating the cultured cells for a response to the drug. In certain embodiments, monolayer(s) of malignant cells are cultured from explants prepared by mincing tumor tissue, and the cells of the monolayer are suspended and plated for chemosenstivity testing. The in vitro response to the drug as determined by the method of the invention is correlative with the patient's in vivo response upon receiving the EGFR inhibitor during chemotherapeutic treatment (e.g., in combination with other standardized or individualized chemotherapeutic regimen). | 11-19-2009 |
| 20110014644 | METHODS FOR PREDICTING A CANCER PATIENT'S RESPONSE TO ANTIFOLATE CHEMOTHERAPY - The present invention provides methods for individualizing therapy for cancer treatment, and particularly for evaluating a patient's responsiveness to one or more antifolate therapeutic agents prior to treatment with such agents. Particularly, the invention provides an in vitro chemoresponse assay for predicting a patient's response to an antifolate agent, such as pemetrexed or methotrexate. | 01-20-2011 |
| 20110129822 | MULTI DRUG RESPONSE MARKERS FOR BREAST CANCER CELLS - The present invention provides methods for preparing a gene expression profile of a breast cancer cell, tumor, or cell line, where the gene expression profile may be evaluated for one or more gene expression signatures indicative of multidrug resistance. The signature may be indicative of resistance to one or more chemotherapeutic agents selected from a Taxol (e.g., Docetaxel or Paclitaxel), an antibiotic (e.g., Doxorubicin or Epirubicin), an antimetabolite (e.g., Fluorouracil and/or Gemcitabine), and an alkylating agent (e.g., Cyclophosphamide). Generally, the gene expression profile contains the level of expression for a plurality of genes listed in FIGS. | 06-02-2011 |
| 20110130302 | BIOLOGICAL PATHWAYS ASSOCIATED WITH CHEMOTHERAPY OUTCOME FOR BREAST CANCER - The present invention provides methods for preparing drug response and/or resistance profiles for breast tumor specimens, or cells derived therefrom. The drug response and/or resistance profiles are useful for determining effective chemotherapeutic agents for treatment of the tumor or cell to thereby individualize patient therapy. In other aspects, the invention provides a method for identifying a pathway or gene expression signature indicative of a breast cancer cell's sensitivity to a chemotherapeutic agent, which is useful for identifying a population response rate, or patient sub-population likely to respond to the drug candidate. | 06-02-2011 |
| 20110207119 | METHODS FOR PREDICTING A CANCER PATIENT'S RESPONSE TO SUNITINIB - The present invention provides methods for individualizing chemotherapy for cancer treatment, and particularly for evaluating a patient's responsiveness to sunitinib prior to treatment. The method comprises expanding malignant cells in culture from a patient's tumor specimen, contacting the cultured cells with one or more active agents including sunitinib, and evaluating or quantifying the response to the active agent(s). The result of the assay is a dose response curve, which may be evaluated using algorithms described herein, so as to quantitatively assess drug sensitivity. The in vitro response to the drug as determined by the method of the invention is correlative with the patient's in vivo response upon receiving sunitinib during chemotherapeutic treatment, in the course of standardized or individualized chemotherapeutic regimen. | 08-25-2011 |
