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Brophy, US

Christine Mary Brophy, Montgomery Village, MD US

Patent application numberDescriptionPublished
20080255979WELLNESS PROGRAM MANAGEMENT AND INTEGRATION WITH PAYROLL VENDOR SYSTEMS - A computer implemented method is disclosed for receiving employee usage information associated with at least one employee's usage of a wellness program. A status level associated with the at least one employee for the wellness program is determined based on the employee usage information. A status level indicates a degree of participation in the wellness program. A data set is created comprising at least the status level associated with the at least one employee. The data set is in a format acceptable by a payroll vendor without conversion of the data set. The data set is then sent to an employer of the at least one employee.10-16-2008

Christopher Brophy, Pittsford, NY US

Patent application numberDescriptionPublished
20090251702Stitching of near-nulled subaperture measurements - A metrology system for measuring aspheric test objects by subaperture stitching. A wavefront-measuring gauge having a limited capture range of wavefront shapes collects partially overlapping subaperture measurements over the test object. A variable optical aberrator reshapes the measurement wavefront with between a limited number of the measurements to maintain the measurement wavefront within the capture range of the wavefront-measuring gauge. Various error compensators are incorporated into a stitching operation to manage residual errors associated with the use of the variable optical aberrator.10-08-2009

Christopher Philip Brophy, Pittsford, NY US

Patent application numberDescriptionPublished
20090137876DIAGNOSTIC CAPSULE WITH PERIPHERAL IMAGING - A diagnostic capsule is disclosed having at least one light source; a rotatable substrate having at least one optical bench; at least one photo-sensitive region; and a circumferential window having an axis substantially parallel to an axis of rotation of the rotatable substrate. Related systems for use with a diagnostic capsule are also disclosed. An endoscopic diagnostic map is further disclosed. The endoscopic diagnostic map has a first dimension corresponding to a rotational position of at least one optical bench on a rotatable substrate of a diagnostic capsule. The endoscopic diagnostic map also has a second dimension corresponding a traveled position of the diagnostic capsule. Related methods of generating an endoscopic05-28-2009

Colleen Brophy, Tempe, AZ US

Patent application numberDescriptionPublished
20080293640Polypeptide inhibitors of HSP27 kinase and uses therefor - The present invention provides polypeptide inhibitors of HSP27 kinase, compositions thereof, and methods for using such polypeptides and compositions for various therapeutic uses.11-27-2008

Colleen Brophy, Scottsdale, AZ US

Patent application numberDescriptionPublished
20090176694Reagents and Methods for Smooth Muscle Therapies - The present invention provides novel polypeptides comprising heat shock protein 20 (HSP20)-derived polypeptides to treat or inhibit smooth muscle vasospasm, as well to treat and inhibit smooth muscle cell proliferation and migration.07-09-2009
20090176695Reagents and Methods for Smooth Muscle Therapies - The present invention provides novel polypeptides comprising heat shock protein 20 (HSP20)-derived polypeptides to treat or inhibit smooth muscle vasospasm, as well to treat and inhibit smooth muscle cell proliferation and migration.07-09-2009
20090258819Reagents and Methods for Smooth Muscle Therapies - The present invention provides novel polypeptides comprising heat shock protein 20 (HSP20)-derived polypeptides to treat or inhibit smooth muscle vasospasm, as well to treat and inhibit smooth muscle cell proliferation and migration.10-15-2009
20100009903Methods for Promoting Wound Healing and/or Reducing Scar Formation - The present invention provides methods for promoting wound healing and/or reducing scar formation, by administering to an individual in need thereof one or more of the heat shock protein 20-derived polypeptides disclosed herein.01-14-2010

Patent applications by Colleen Brophy, Scottsdale, AZ US

Colleen Brophy, Nashville, TN US

Patent application numberDescriptionPublished
20100004165Novel Protein Transduction Domains and Uses Therefor - The present invention provides novel transduction domains, compositions comprising such transduction domains, and their use for in vivo molecular delivery.01-07-2010
20110288036Methods for Treating or Preventing Vascular Graft Failure - The described invention provides pharmaceutical compositions and methods for treating or preventing vascular graft failure in a subject in need of such treatment, the method comprising administering a therapeutically effective amount of a composition comprising a polypeptide of amino acid sequence YARAAARQARAKALARQLGVAA (SEQ ID NO: 1) or a functional equivalent thereof, and a pharmaceutically acceptable carrier. The methods also are clinically useful for treating a pre-atherosclerotic intimal hyperplasia condition.11-24-2011

Colleen M. Brophy, Nashville, TN US

Patent application numberDescriptionPublished
20110028398METHODS FOR TREATING AND LIMITING FIBROTIC DISORDERS AND KELOIDS - The present invention provides methods for treating and/or limiting fibrotic disorders and/or treating or limiting scars selected from the group consisting of keloids and hypertrophic scars comprising administering to an individual in need thereof an amount effective to treat and/or limit scars selected from the group consisting of keloids and hypertrophic scars of a polypeptide comprising an HSP20-related polypeptide.02-03-2011
20110190572Methods and Compositions for Vein Harvest and Autografting - The leading cause of graft failure is the subsequent development of intimal hyperplasia, which represents a response to injury that is thought to involve smooth muscle proliferation, migration, phenotypic modulation, and extracellular matrix (ECM) deposition. Surgical techniques typically employed for vein harvest—stretching the vein, placing the vein in low pH, solutions, and the use of toxic surgical skin markers—are shown here to cause injury. The invention therefore provides for non-toxic surgical markers than also protect against stretch-induced loss of functional viability, along with other additives. Devices and compositions for reducing physical stress or protecting from the effects flowing therefrom, also are provided.08-04-2011

Erin Brophy, Dover, NH US

Patent application numberDescriptionPublished
20120115162ANTI-FATTY ACID AMIDE HYDROLASE-2 ANTIBODIES AND USES THEREOF - Antibodies that specifically bind to fatty acid amide hydrolases and methods of using the antibodies are provided herein.05-10-2012

James S. Brophy, Independence, MN US

Patent application numberDescriptionPublished
20080317913Modification of Particle Morphology to Improve Product Functionality - A method for improving the functional and organoleptic properties of a product is described. The method involves modifying the particles within the product to meet certain particle morphology parameters.12-25-2008
20090285935SYSTEM FOR MAKING PRODUCTS WITH IMPROVED PARTICLE MORPHOLOGY AND PARTICLE DISTRIBUTION AND PRODUCTS - A method for improving the physical, functional and organoleptic properties of product particles is described for fiber, protein, carbohydrate and cellulosic materials. The method involves modifying the particles within the product to meet certain particle morphology parameters. Products themselves also are disclosed, and these include corn-originating products, specifically including products for producing ethanol soybean-originating products, and other products.11-19-2009
20110183050MODIFICATION OF PARTICLE MORPHOLOGY TO IMPROVE PRODUCT FUNCTIONALITY - A method for improving the functional and organoleptic properties of a product is described. The method involves modifying the particles within the product to meet certain particle morphology parameters.07-28-2011
20110311819SYSTEM FOR MAKING PRODUCTS WITH IMPROVED PARTICLE MORPHOLOGY AND PARTICLE DISTRIBUTION AND PRODUCTS - A method for improving the physical, functional and organoleptic properties of product particles is described for fiber, protein, carbohydrate and cellulosic materials. The method involves modifying the particles within the product to meet certain particle morphology parameters. Products themselves also are disclosed, and these include corn-originating products, specifically including products for producing ethanol, soybean-originating products, and other products.12-22-2011

Patent applications by James S. Brophy, Independence, MN US

Jere J. Brophy, Loveland, OH US

Patent application numberDescriptionPublished
20080226029Medical device including scanned beam unit for imaging and therapy - A medical device includes a radiation source assembly having at least two radiation sources, where one or more of the radiation sources is adapted to generate an imaging beam for use in visualization of a scene and one or more of the radiation sources is adapted to generate a therapeutic beam for treatment of a medical condition. An optical fiber for directing radiation energy from the radiation source assembly toward a distal end of the medical device in the form of a beam. A reflector that receives the beam from the optical fiber, the reflector configured to direct the beam onto a field-of-view. A receiving system including a detector arranged and configured to receive radiation from the field-of-view to generate a viewable image. The imaging beam and the therapeutic beam are directed to follow a common path from the at least two radiation sources to the reflector.09-18-2008
20080312490METHODS AND DEVICES FOR REPAIRING DAMAGED OR DISEASED TISSUE USING A SCANNING BEAM ASSEMBLY - A method for repairing or modifying an area of a patient's anatomy that comprises directing at least a portion of a scanning beam assembly to an area of a patient's anatomy, applying a radiation-responsive agent to portion of the anatomy, and exposing the radiation-responsive agent to radiation directed onto the agent by the reflector to cause the agent to therapeutically interact with the site. The scanning beam assembly including a radiation source capable of emitting radiation, a reflector that receives the radiation from the radiation source to direct the radiation onto the anatomy, wherein the reflector oscillates in at least two directions to create a scan of the anatomy, a detector to detect radiation returned from the anatomy, and a controller to convert the detected radiation into a displayable anatomy image.12-18-2008
20090021818MEDICAL SCANNING ASSEMBLY WITH VARIABLE IMAGE CAPTURE AND DISPLAY - A scanned beam imaging system including a housing suitable for insertion into a body and a radiation source configured to direct a beam of radiation into or through the housing and onto an area within the body. The scanned beam imaging system further includes an adjustable element inside the housing and positioned to reflect the beam of radiation or to receive the beam of radiation therethrough, wherein the adjustable element is physically adjustable to vary a property of the beam of radiation that is reflected thereby or received therethrough. The scanned beam imaging system further includes a collector configured to receive radiation returned from the area within the body.01-22-2009

John M. Brophy, Taylorsville, UT US

Patent application numberDescriptionPublished
20100080734TIP PLATE FOR HIGH THROUGHPUT SCREENING APPLICATIONS - A pipette tip plate includes individual tips organized in ranks and files to match in pattern the array of wells in a standard well plate and held together by a web structure which permits individual tips to move into registration with individual pins of a robotic head.04-01-2010

Kristine M. Brophy, Richmond, VA US

Patent application numberDescriptionPublished
20090155353MICROEMULSIONS FOR PHARMACEUTICAL COMPOSITIONS - The invention provides microemulsion pharmaceutical compositions comprising pharmaceutical actives which are hydrotropes that facilitate formation of microemulsions. The invention further provides methods of making the compositions and utilization of the compositions in liquid fill soft shell capsules including capsules having shells of non-animal derived materials (e.g. non-ADRM).06-18-2009

Linda Brophy, Independence, MN US

Patent application numberDescriptionPublished
20080317913Modification of Particle Morphology to Improve Product Functionality - A method for improving the functional and organoleptic properties of a product is described. The method involves modifying the particles within the product to meet certain particle morphology parameters.12-25-2008
20090285935SYSTEM FOR MAKING PRODUCTS WITH IMPROVED PARTICLE MORPHOLOGY AND PARTICLE DISTRIBUTION AND PRODUCTS - A method for improving the physical, functional and organoleptic properties of product particles is described for fiber, protein, carbohydrate and cellulosic materials. The method involves modifying the particles within the product to meet certain particle morphology parameters. Products themselves also are disclosed, and these include corn-originating products, specifically including products for producing ethanol soybean-originating products, and other products.11-19-2009
20110183050MODIFICATION OF PARTICLE MORPHOLOGY TO IMPROVE PRODUCT FUNCTIONALITY - A method for improving the functional and organoleptic properties of a product is described. The method involves modifying the particles within the product to meet certain particle morphology parameters.07-28-2011
20110311819SYSTEM FOR MAKING PRODUCTS WITH IMPROVED PARTICLE MORPHOLOGY AND PARTICLE DISTRIBUTION AND PRODUCTS - A method for improving the physical, functional and organoleptic properties of product particles is described for fiber, protein, carbohydrate and cellulosic materials. The method involves modifying the particles within the product to meet certain particle morphology parameters. Products themselves also are disclosed, and these include corn-originating products, specifically including products for producing ethanol, soybean-originating products, and other products.12-22-2011

Patent applications by Linda Brophy, Independence, MN US

Michael Brophy, Smithfield, RI US

Patent application numberDescriptionPublished
20080310779RESTRAINED, REVERSE MULTI-PAD BEARING ASSEMBLY - A hydrodynamic fluid film bearing assembly has a stationary retaining member defining a central opening and having an inner surface lined by a foil assembly comprised of a plurality of foil subassemblies. Each foil subassembly comprises a first compliant foil, a second compliant foil, and a spring foil, and subtending a rotational segment, less than all, of the inner surface of the retaining member. The complaint foils and the spring foil of each foil subassembly are held within the retaining member in such a way that sliding travel of one compliant foil along the inner surface of the opening is in the opposite rotational direction of sliding travel of the other compliant foil and the spring foil. The foil subassemblies may be restrained from undesired movement during operation by a retention tab extending from the foil subassembly which engages a channel and recess feature formed in the retaining member.12-18-2008

Steven M. Brophy, Saline, MI US

Patent application numberDescriptionPublished
20110178978CHARACTERIZING AND PREDICTING AGENTS VIA MULTI-AGENT EVOLUTION - A method of predicting the behavior of software agents in a simulated environment involving modeling a plurality of software agents representing entities to be analyzed, which may be human beings. Using a set of parameters that governs the behavior of the agents, the internal state of at least one of the agents is estimated by its behavior in the simulation, including its movement within the environment. This facilitates a prediction of the likely future behavior of the agent based solely upon its internal state; that is, without recourse to any intentional agent communications. In one embodiment, the simulated environment is based upon a digital pheromone infrastructure. The simulation integrates knowledge of threat regions, a cognitive analysis of the agent's beliefs, desires, and intentions, a model of the agent's emotional disposition and state, and the dynamics of interactions with the environment.07-21-2011

Timothy J. Brophy, Columbia, MD US

Patent application numberDescriptionPublished
20090028564Dual Broadcast and Narrowcast Systems and Methods - Various embodiments of dual broadcast and narrowcast systems and methods are disclosed. One method embodiment, among others, comprises the steps of receiving optical narrowcast signals and converting the optical narrowcast signals to a radio frequency (RF) domain at a first photodiode, receiving optical broadcast signals and converting the optical broadcast signals to the radio frequency (RF) domain at a second photodiode, and combining the RF domain narrowcast and broadcast signals for transmission over a medium.01-29-2009

Timothy J. Brophy, Schwenksville, PA US

Patent application numberDescriptionPublished
20080205339Auto-Provisioning of a Mobile Computing Device for Operation With A Wireless Network - An automatic provisioning methodology for a mobile computing device in a wireless network is disclosed herein. The mobile computing device can support open communication with a wireless switch, which is configured to function as a load request proxy between the mobile computing device and a mobile services system on the wireless network. The mobile services system sends provisioning data to the wireless switch (using secure communications), which in turn sends the provisioning data to the mobile computing device. The mobile computing device can then use the provisioning data to configure its software applications, security settings, and the like.08-28-2008
20100080402System and Method for Volume Control Based on Location - A system and method control a volume based on location. The system comprises a switch and an asset. The switch is for a network including an operating area for a region. The region is divided into a plurality of zones. The asset is disposed in one of the zones. The asset includes an audio output device. The audio output device is set to a predetermined volume level as a function of one of the plurality of the zones in which the asset is disposed.04-01-2010

Victoria Brophy, Martinez, CA US

Patent application numberDescriptionPublished
20100173311NUCLEIC ACID AMPLIFICATION WITH ALLELE-SPECIFIC SUPPRESSION OF SEQUENCE VARIANTS - The present invention is an improved method of selective amplification of certain variants of the target sequence, enhanced by allele-specific suppression of amplification of one or more of the other variants of the target sequence. The improvement is accomplished by providing an oligonucleotide, capable of hybridizing to the desired variant of the target sequence with the lesser affinity than to the undesired variants of the target sequence and optionally, by providing chemically modified primers and hot-start conditions.07-08-2010