Brooks, NY
Adam Brooks, Dexter, NY US
Patent application number | Description | Published |
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20160074861 | Portable Analytic Device and Methods of Use Thereof - A portable analytic apparatus is provided that is capillary-driven and capable of detecting analytes within a sample and providing an unambiguous positive/negative response. Embodiments provide for a hydrophobic detection reagent within a hydrophilic porous media, where a hydrophobic detection reagent changes to hydrophilic products in a presence/absence of a target analyte. This change from hydrophobic to hydrophilic provides a means to achieve a desired result of generating an unambiguous qualitative and/or quantitative positive/negative readout by forcing samples to wick at differential rates through hydrophilic regions towards a detection region. Suitable hydrophobic detection reagents are also provided. | 03-17-2016 |
Amber Brooks, Clifton Park, NY US
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20140014403 | ENERGY STORAGE AND DISPENSING FLEXIBLE SHEETING DEVICE - An energy storing and dispensing sheeting having addressable energy storing cells is disclosed. A free-forming process of fabricating energy storing sheets is disclosed. An interconnect interface for operatively coupling the energy storing sheeting to an external element is disclosed. A flexible printed circuit board with patterned energy storing layers is disclosed. An adhesive, flexible energy storing sheeting is disclosed. Energy storing sheet that can be mechanically tuned and patterned as a structural building material is disclosed. A networked grid storage embodiment of a structural energy storing sheeting is disclosed. An energy storing sheeting powering computer memory and integrated circuits is disclosed. A puncture tolerant energy storage device is disclosed. An ultracapacitor having a separator, symmetric or asymmetric electrodes, electrolyte and a current collector is disclosed. A battery, supercapacitor and hybrid device is disclosed. Variable RC time constants and voltages within an energy storing sheeting are disclosed. | 01-16-2014 |
20140133067 | COMPLIANT ENERGY STORING STRUCTURAL SHEET - Disclosed herein is a structural sheet includes an energy storage density that is greater than 10-mWh/ft2 and is capable of withstanding greater than 5-KPa stress under at least 5% strain. Further provided is an energy storing structural sheet comprising an electrically conducting current carrying layer that is print formed over a sub assembly that comprises a separator, a foundation, an electrode, and a current bus. | 05-15-2014 |
20150187507 | COMPLIANT ENERGY STORING STRUCTURAL SHEET - Disclosed herein is a structural sheet includes an energy storage density that is greater than 10-mWh/ft2 and is capable of withstanding greater than 5-KPa stress under at least 5% strain. Further provided is an energy storing structural sheet comprising an electrically conducting current carrying layer that is print formed over a sub assembly that comprises a separator, a foundation, an electrode, and a current bus. | 07-02-2015 |
Andrew Brooks, New York, NY US
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20140342938 | Compositions and Methods for Functional Quality Control for Human Blood-Based Gene Expression Products - Methods for assessing the integrity of an RNA sample from a given tissue or blood type are disclosed. | 11-20-2014 |
Andrew I. Brooks, New York, NY US
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20130178376 | Compositions and Methods for High-Throughput Nucleic Acid Analysis and Quality Control - Methods for improved quality control of nucleic acid containing biological samples utilized in high-throughput situations such as biorepositories engaged in the collection, processing, storage, distribution and analysis of such samples are disclosed. | 07-11-2013 |
Brent William Brooks, Brooklyn, NY US
Patent application number | Description | Published |
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20120331496 | METHODS AND APPARATUS FOR PRESENTING SOCIAL NETWORK CONTENT IN CONJUNCTION WITH VIDEO CONTENT - Methods and apparatus for generating, distributing, and/or presenting social networking content in conjunction with video content are described. In accordance with various embodiments, social networking related information, e.g., comments, remarks and/or a twitter feed, are displayed in conjunction with the display of video to which the social networking information relates. The social networking related information may be displayed on the same or a different device from that which is used to display the video comments. In some embodiments, the social networking information, e.g., comments on a program, event or broadcast, are displayed on a personal computer or other device such as a mobile telephone, while video content is being viewed, e.g., on a television which is provided video content via a set top box. A knowledgeable moderator can review, supplement, add and delete comments in real time enhancing the overall social networking session. | 12-27-2012 |
Chris Brooks, Glen Head, NY US
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20130079723 | MEDICAL SECUREMENT DEVICE WITH TIMER - A medical article, such as an anchor pad for stabilizing a medical line and/or a medical line securement device to a patient's skin, is provided with a timer. The timer can measure and provide an indication of elapsed time. The timer can be flexible or rigid, and can be disposed directly on the anchor pad, on a flexible or rigid substrate disposed on the anchor pad, or on a retainer supported by the anchor pad. The anchor pad with integral timer provides an easy-to-use visual indicator of elapsed time since placement of the medical line, offering a reliable way to signal when the medical line should be re-sited. | 03-28-2013 |
Christopher Brooks, New York, NY US
Patent application number | Description | Published |
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20150079135 | METHODS FOR TREATING AND MONITORING THE STATUS OF CANCER - Provided herein are methods for treating cancer in a subject comprising administering to the subject a therapeutically effective amount of a peptide derived from the EphA2 protein and/or the IL-13Rα2 protein and monitoring the amount of cancer stem cells in said subject. Also provided herein are methods for monitoring the efficacy of an EphA2 peptide-based cancer treatment or an IL-13Rα2 peptide-based cancer treatment in a patient with cancer, comprising monitoring the amount of cancer stem cells in said subject prior to, during, and/or following cancer treatment of a patient. | 03-19-2015 |
20150139939 | CANCER STEM CELL TARGETED CANCER VACCINES - Provided herein are cancer stem cell targeted cancer vaccines and methods for treating and vaccinating against cancer. Also contained herein are regimens by which cancer stem cell targeted cancer vaccines are administered, such regimens comprising peptides, compositions, immunomodulatory agents, and emulsifiers. Also provided are the patient populations to which the regimens are to be administered, and the dosages, schedules, route of administration for the regimens. | 05-21-2015 |
Christopher Brooks, Glen Head, NY US
Patent application number | Description | Published |
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20090048504 | Medical electrode systems and methods - Systems, methods, and devices are provided for creating and applying electrodes and electrode systems to a wound or skin. An electrode may be applied as a single electrode strip using a dispenser. An electrode may also be cut to size from a single sheet of electrode. Additionally, an electrode may be formed from a plurality of electrode segments which may be connected together. Electrodes can also be incorporated as part of drainage tubes. A medical electrode kit may be provided that includes multiple electrode segments and connectors, multiple electrodes, and multiple control modules. In addition, electrodes or electrode systems may be provided with a color scoring chart. An electrode system may be configured to interface with a selected body part. Electrode systems may include sensors and electrodes configured for application to areas outside of a wound or the skin intended to be treated. | 02-19-2009 |
20090048635 | Medical electrode systems and methods - Systems, methods, and devices are provided for creating and applying electrodes and electrode systems to a wound or skin. An electrode may be applied as a single electrode strip using a dispenser. An electrode may also be cut to size from a single sheet of electrode. Additionally, an electrode may be formed from a plurality of electrode segments which may be connected together. Electrodes can also be incorporated as part of drainage tubes. A medical electrode kit may be provided that includes multiple electrode segments and connectors, multiple electrodes, and multiple control modules. In addition, electrodes or electrode systems may be provided with a color scoring chart. An electrode system may be configured to interface with a selected body part. Electrode systems may include sensors and electrodes configured for application to areas outside of a wound or the skin intended to be treated. | 02-19-2009 |
20110245777 | ABSORBENT CATHETER PAD - A pad or medical article is configured to absorb fluids that are discharged from a catheter assembly and/or medical line. The pad includes a body member that can include a backing layer and an absorbent layer disposed over the backing layer. The absorbent layer can include a groove connecting the proximal end of the layer with a recess formed in a surface of the layer. The groove and recess can be configured to draw fluids that come into contact with the layer to the recess to evenly distribute the liquid throughout the absorbent layer. The medical article can also include a retention member disposed on the body member. The retention member can form a receiving space or channel so as to permit at least a portion of a catheter assembly or medical line to be placed within the receiving space. | 10-06-2011 |
Christopher J. Brooks, Glen Cove, NY US
Patent application number | Description | Published |
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20120265147 | STABILIZING DEVICE HAVING A LOCKING COLLET - A medical article, such as a catheter hub, is stabilized on a patient with a retainer having a base and clamp or moveable collet. A lever is configured to move the collet in a longitudinal direction relative to the based to secure the medical article to the retainer. When rotated, the lever pulls the collet in a direction away from the patient while collapsing the collet around at least a portion of the catheter hub. | 10-18-2012 |
20120271239 | STABILIZING DEVICE HAVING A SNAP CLAMP - A medical article, such as a connector fitting, is stabilized on a patient with a retainer having a base and moveable walls. Actuation surfaces configured to move the walls in at least a lateral direction towards each other are suspended above the base by a pair of supports. When pressed together, inner surfaces of the walls form a channel configured to encircle the medical article. The medical article may be pressed down against the actuation surfaces by a medical provider to cause the walls to encircle the medical article. Thereafter, the medical provider may snap the walls together using a latching mechanism to stabilize the medical article on the patient. | 10-25-2012 |
20120271240 | STABILIZING DEVICE FOR AN EXTENSION SET - A medical article, such as a connector fitting or extension set, is stabilized on a patient with a retainer and a dressing integrally attached to an anchor pad supporting the retainer. The connector fitting or extension set may be integrally formed with the retainer. The connector fitting or extension set may comprise a spin nut configured to secure to a catheter hub having a catheter connected thereto. One or more of the anchor pad, dressing, and catheter may comprise an antibacterial or antimicrobial agent. | 10-25-2012 |
20130138080 | MEDICAL ARTICLE WITH ROTATABLE WINGS - A medical article is configured to provide access to a patient's vasculature. The medical article includes an elongated body and a pair of stabilizing wings that extend from the elongated body and are configured to stabilize the medical article on a patient. The stabilizing wings are configured to rotate together or independently about the longitudinal axis of the elongated body between at least a first configuration and a second configuration. The elongated body can include a one-way valve disposed therein. The medical article can also one or more adhesive layers configured to releasably attach at least a portion of the wings to a patient. | 05-30-2013 |
Christopher J. Brooks, Glen Head, NY US
Patent application number | Description | Published |
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20100174343 | APPARATUS AND METHODS FOR FACILITATING WOUND HEALING AND TREATING SKIN - Electrode systems and methods are provided for applying electrical stimulation to a wound or skin. The electrode systems may include a feedback sensor configured to detect at least one wound healing factor or other treatment factors and may adjust the electrical stimulation based on feedback sensor measurements. The electrode systems may include multiple center electrodes for attachment to the wound. Multiple therapies may be stored on the electrode systems and a selected one of the stored therapies may be applied. A timer may be included to indicate the length of time a therapy has been applied. The electrode system may include a control module configured as a flexible circuit which conforms to the shape of the wound or the skin to which it is applied. In addition, a medical kit may be supplied for use in applying therapies, including multiple control modules and multiple electrodes. | 07-08-2010 |
20120028541 | Multi-faceted brassiere assembly - A brassiere generally conformed to the shape of a female upper torso comprising (1) a front portion comprising: a left mesh panel and a right mesh panel; an internal inset pouch; a brassiere insert; a lateral adjustment strap; a first lower panel; a second lower panel; a chest band; a left upper panel wherein the bottom portion of the left upper panel extends from the top portion of the left mesh panel, toward the shoulder of a user; a right upper panel; a left adjustable strap; and a right adjustable strap; (2) side portions comprising: a left adjustable side closure and a right adjustable side closure; and (3) a back portion comprising: a dorsal panel having a octagonal union at the center thereof; a back band; a left upper dorsal strap; a right upper dorsal strap; a left lower dorsal strap; and a right lower dorsal strap. | 02-02-2012 |
20150025615 | Delivery Mechanism for Implantable Stent - A system including a longitudinally elongated housing, a member for incremental rotation of a screw, which moves the screw longitudinally, and a longitudinal sheath connected to the screw. The system has a delivery configuration in which a sheath covers a stent bed, and a deployed configuration in which the sheath does not cover the stent bed because manipulation of the member has rotated the screw, which has moved the screw longitudinally, pulling the sheath off of the stent bed. | 01-22-2015 |
20150367102 | Securement Device Having An Integral Strap And Dressing - A medical article, such as a catheter hub or extension set, is stabilized on a patient with a retainer and a dressing integrally attached to an anchor pad supporting the retainer. The catheter hub or extension set may be integrally formed with the retainer. The retainer may comprise a channel and an integral strap. The channel may include an abutment. One or more of the anchor pad, dressing, and catheter may comprise an antibacterial or antimicrobial agent. | 12-24-2015 |
Christopher John Brooks, Glen Cove, NY US
Patent application number | Description | Published |
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20150038905 | APPARATUS AND METHODS FOR OCULAR INJECTION - An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location. | 02-05-2015 |
20150051581 | APPARATUS AND METHODS FOR OCULAR INJECTION - An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location. | 02-19-2015 |
Donald Brooks, Ithaca, NY US
Donald E. Brooks, Ithaca, NY US
Patent application number | Description | Published |
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20080218774 | Configurable printer for different locations and methods of configuring a printer for different locations - A configurable printer for different locations and methods for configuring a printer for different locations are provided. The printer includes memory loaded with different versions of firmware. Each version of firmware may enable a different printer configuration for a corresponding location. The printer also includes an interface for accepting a signal from a control device. The signal may comprise instructions to the printer to load a particular version of the firmware that corresponds to the location of the control device. | 09-11-2008 |
20080278526 | Ink jet printer with expanded validation print zone - An ink jet printer has two print cartridges. For example, one cartridge can carry black ink and the other red ink. Both cartridges are used to print on a receipt with a narrow print zone of, for example, 2.5 inches. Only the black cartridge is used to print on a cut sheet for validation purposes. By lengthening the time that the print head of the black cartridge is actuated to spray ink, a wider print zone (e.g., 3.5 inches) can be provided for the cut sheet. | 11-13-2008 |
20090138635 | Method and apparatus for controlling a peripheral via different data ports - A peripheral such as a printer is controlled to receive data from different data ports. A first port receives data formatted according to a first protocol. A second port receives data formatted according to a second protocol. A first processor is associated with the peripheral. A second processor is associated with the second port. A switch is adapted to receive (i) first data from the first port and (ii) second data from the second port after processing by the second processor. The switch is controlled in response to a message received via the second port to couple either the first data or second data to the first processor for use in controlling the peripheral. New firmware can be downloaded to the peripheral via the second port in response to the message. The message can be communicated to the first processor via a separate port at the first processor and a memory shared with the second processor. | 05-28-2009 |
Edward J. Brooks, Sunnyside, NY US
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20110010250 | Method and system for tracking and sending advertisements printed on the interior of shipping containers - Disclosed is a system and method for sending and tracking printed advertisements. The method includes receiving an advertisement order to disseminate an advertisement message from an advertiser, sending a printing order to print a design on a wall of a shipping container, wherein the design includes the advertisement message and a unique identification code linked to the advertisement message; sending the shipping container to an item seller, instructing the item seller to configure the shipping container such that the design appears on an inside wall of the shipping container, and further instructing the item seller to submit destination information, the unique identification code, and origination information of the shipping container, sending an item to a destination using the shipping container, receiving the destination information, the unique identification code, and the origination information from the item seller, compensating the item seller upon receiving the destination information, the unique identification code, and the origination information submitted by the item seller, and providing a report of at least the destination information, the advertisement message, and the origination information to the advertiser. | 01-13-2011 |
Harold Brooks, Holliswood, NY US
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20140014126 | HOT-WIRE CONTROL FOR AN ELECTRONIC CIGARETTE - An electronic cigarette (“e-Cig”) may include functionality for monitoring and controlling the thermal properties of the e-Cig. The system and method described herein may monitor a temperature based on a resistor (i.e. hot wire) near the wick and model the thermal cycle of an e-Cig. The model can be used for controlling the temperature of the e-Cig and preventing burning. The temperature control may dictate optimal conditions for atomization and smoke generation in an e-Cig while avoiding hotspots and burning to the atomizer or cartomizer. | 01-16-2014 |
Harold Albert Brooks, Clifton Park, NY US
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20120167494 | MODULAR STAIRCASE SYSTEMS - Modular staircases and staircase assemblies comprising components with notches that fit into and interweave with each other. Certain embodiments of modular staircases have at least two webs, wherein the perimeter of each web resembles a staircase with steps. The webs may be coupled together by a plurality of cross-beams. Each of the webs and the cross-beams may have notches that fit into and interweave with each other to form the basic structure of a staircase. The staircase may also be provided with cover pieces to cover the exposed webs and cross beams, and thus, to provide a surface for a user to sit or step on. Embodiments described herein are modular, in that they may be coupled together in various configurations and thus coupled to straight walls, curved walls, or any combination thereof. Additionally, embodiments described herein may be installed in either vinyl liner-type pools or concrete pools. | 07-05-2012 |
20160102470 | Seamless Pool Liner and Method of Making the Same - A method of making a pool liner, said pool liner having a floor section, a wall section and substantially invisible seams, said method comprising the steps of: providing a plurality of floor sheets wherein each sheet of said plurality of floor sheets has an edge; arranging said floor sheets in a pre-determined direction such that at least one edge of one sheet of said first plurality of floor sheets overlaps an adjacent edge of one sheet of said first plurality of floor sheets thereby creating a floor sheet to floor sheet intersection; heat welding said overlapping floor sheets at said floor sheet to floor sheet intersection; providing at least one wall sheet where said at least one wall sheet has an edge; placing said at least one wall sheet generally perpendicularly relative to said plurality of floor sheets; overlapping said at least one wall sheet with said floor sheets thereby creating a floor sheet to wall sheet intersection; and heat welding said at least one wall sheet with overlapping floor sheets at said floor to wall intersection. | 04-14-2016 |
James Brooks, Troy, NY US
Patent application number | Description | Published |
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20130277505 | METHOD AND APPARATUS FOR LIMITING IN-TRAIN FORCES OF A RAILROAD TRAIN - An apparatus includes a first element for identifying planned applications of tractive effort and braking effort for a railway vehicle while traversing a track segment. The apparatus includes a second element for determining a slack condition of the railway vehicle at one or more locations on the track segment in advance of the railway vehicle traversing the track segment based on the planned applications of tractive effort and braking effort. The apparatus includes a third element for redetermining the slack condition at the one or more locations based on at least one deviation from the planned applications of tractive effort and braking effort. | 10-24-2013 |
20140094998 | CONTROL SYSTEM AND METHOD FOR REMOTELY ISOLATING POWERED UNITS IN A VEHICLE SYSTEM - A control system includes an energy management system and an isolation control system. The energy management system generates a trip plan that designates operational settings of a vehicle system having powered units that generate tractive effort to propel the vehicle system. The energy management system determines a tractive effort capability of the vehicle system and a demanded tractive effort of a trip. The energy management system identifies a tractive effort difference between the tractive effort capability of the vehicle system and the demanded tractive effort of the trip and selects at least one of the powered units based on the tractive effort difference. The isolation module remotely turns the selected powered unit to an OFF mode such that the vehicle system is propelled along the route during the trip by the powered units other than the selected powered unit. | 04-03-2014 |
James Brooks, Niskayuna, NY US
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20150232097 | ENERGY MANAGEMENT SYSTEM AND METHOD FOR VEHICLE SYSTEMS - An energy management system and method for a vehicle system operate the vehicle system according to a current trip plan as the vehicle system travels along a route during a trip. The current trip plan designates operational settings of the vehicle system. The system and method also revise the current trip plan into a revised trip plan responsive to current, actual operation of the vehicle system differing from the current trip plan by at least a designated threshold amount. The revised trip plan designates operational settings of the vehicle system and includes an initial designated operational setting that matches the current, actual operation of the vehicle system. | 08-20-2015 |
James A. Brooks, Williamson, NY US
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20110236668 | Films Having Low Density and Low Haze - Disclosed are single and multi-layer films having low haze and low density properties, comprising at least one polymeric layer and at least one density reduction agent, wherein the film has a haze ≦35% and a density (D) of at least 1% lower than the density of the polymer. The density reduction agent may be added to, for example, a core layer, one or more tie layers, or a core layer and one or more tie layers. Processes for the manufacture of these films, and the use of these films as labels and packaging products are disclosed. | 09-29-2011 |
James D. Brooks, Schenectady, NY US
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20140188375 | SYSTEM AND METHOD FOR ASYNCHRONOUSLY CONTROLLING A VEHICLE SYSTEM - A method includes identifying power outputs to be provided by propulsion-generating vehicles of a vehicle system for different locations along a route and calculating handling parameters of the vehicle system at the locations along the route. The handling parameters are representative of at least one of coupler forces, coupler energies, relative vehicle velocities, or natural forces exerted on the vehicle system. The method also includes determining asynchronous operational settings for the propulsion-generating vehicles at the locations. The asynchronous operational settings represent different operational settings that cause the propulsion-generating vehicles to provide at least the power outputs at the locations while changing the handling parameters of the vehicle system to designated values at the locations. The method further includes communicating the asynchronous operational settings to the propulsion-generating vehicles in order to cause the propulsion-generating vehicles to implement the asynchronous operational settings at the different locations. | 07-03-2014 |
Maggie-Reilly Brooks, Scarsdale, NY US
Patent application number | Description | Published |
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20100070522 | SYSTEMS AND METHODS FOR GENERATING AND DISPLAYING AN INTELLECTUAL PROPERTY RIGHTS PROFILE FOR A MEDIA PRESENTATION - A system, computer readable media, GUI, and apparatus are provided that are configured to generate and display an intellectual property rights profile for a media presentation. Information to be included in an intellectual property rights profile may be entered into a provided data entry template by, for example, a user or administrator of the media presentation. Uploaded documents may be added to an intellectual property rights profile and later accessed by a subsequent user. In some cases, a status, for example, complete or incomplete, may be determined for an intellectual property rights profile and an action may be initiated based on the status. | 03-18-2010 |
20150310572 | SYSTEMS AND METHODS FOR GENERATING AND DISPLAYING AN INTELLECTUAL PROPERTY RIGHTS PROFILE FOR A MEDIA PRESENTATION - A system, computer readable media, GUI, and apparatus are provided that are configured to generate and display an intellectual property rights profile for a media presentation. Information to be included in an intellectual property rights profile may be entered into a provided data entry template by, for example, a user or administrator of the media presentation. Uploaded documents may be added to an intellectual property rights profile and later accessed by a subsequent user. In some cases, a status, for example, complete or incomplete, may be determined for an intellectual property rights profile and an action may be initiated based on the status. | 10-29-2015 |
Peter Brooks, Carmel, NY US
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20080233133 | Humanized collagen antibodies and related methods - The invention provides a grafted antibody, or functional fragment thereof, comprising one or more complementarity determining regions (CDRs) having at least one amino acid substitution in one or more CDRs of a heavy chain CDR, where the grafted antibody or functional fragment thereof has specific binding activity for a cryptic collagen epitope. The invention also provides methods of using an antibody having specific binding activity for a cryptic collagen epitope, including methods of inhibiting angiogenesis, tumor growth, and metastasis. | 09-25-2008 |
20080260733 | HUMANIZED COLLAGEN ANTIBODIES AND RELATED METHODS - The invention provides a grafted antibody, or functional fragment thereof, comprising one or more complementarity determining regions (CDRs) having at least one amino acid substitution in one or more CDRs of a heavy chain CDR, where the grafted antibody or functional fragment thereof has specific binding activity for a cryptic collagen epitope. The invention also provides methods of using an antibody having specific binding activity for a cryptic collagen epitope, including methods of inhibiting angiogenesis, tumor growth, and metastasis. | 10-23-2008 |
20100303726 | HUMANIZED COLLAGEN ANTIBODIES AND RELATED METHODS - The invention provides a grafted antibody, or functional fragment thereof, comprising one or more complementarity determining regions (CDRs) having at least one amino acid substitution in one or more CDRs of a heavy chain CDR, where the grafted antibody or functional fragment thereof has specific binding activity for a cryptic collagen epitope. The invention also provides methods of using an antibody having specific binding activity for a cryptic collagen epitope, including methods of inhibiting angiogenesis, tumor growth, and metastasis. | 12-02-2010 |
Peter C. Brooks, Carmel, NY US
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20100323002 | INHIBITION OF MELANOGENESIS AND MELANOMA METASTASIS WITH P-AMINO BENZOIC ACID (PABA) - The present invention relates to the inhibition of melanogenesis with para-aminobenzoic acid (PABA) and its use in treating melanotic cancer. | 12-23-2010 |
Raymond Brooks, Spencerport, NY US
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20140049250 | On The Enhancements of Planar Based RF Sensor Technology - A radio frequency sensor system includes a printed circuit board (PCB). The PCB includes a first exterior layer, a second exterior layer, a first interior layer, a second interior layer, and an inner perimeter that defines an aperture through the PCB. The PCB also includes a first loop. The first loop includes a first plurality of sensor pads coupled to a first plurality of vias by a first plurality of traces. The first plurality of sensor pads is arranged on the inner perimeter. The PCB also includes a second loop. The second loop includes a second plurality of sensor pads coupled to a second plurality of vias by a second plurality of traces. The second plurality of sensor pads is arranged on the inner perimeter. A core ring is embedded within the first interior layer proximal to the first plurality of sensor pads, the first plurality of vias, and the first plurality of traces. A center conductor, for carrying RF current, extends through the aperture. The first and second loops generate an electrical signal based on the first and second plurality of sensor pads, the first and second plurality of vias, the first and second plurality of traces, and the core ring. | 02-20-2014 |
Robert W. Brooks, Owego, NY US
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20090158218 | Structured model navigator - A system for organizing and searching data that relates to a product of manufacture includes a database module configured to store values for a plurality of attributes for each of a plurality of components. A portion of the plurality of components is employed in the product of manufacture. A processing module is configured to organize the plurality of components into one of a plurality of user selectable product structures. Each product structure is based on the values of one of the plurality of attributes. A display is configured to display the selected product structure of the article of manufacture with each of the components displayed within the selected structure. | 06-18-2009 |
Samantha A. Brooks, Newfield, NY US
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20100184025 | METHOD FOR SCREENING FOR A TOBIANO COAT COLOR GENOTYPE - A method for screening for a Tobiano genotype includes obtaining a nucleic acid from an equine animal, and analyzing the nucleic acid for the presence of an inversion in a chromosome ECA3q which is indicative of the genotype for Tobiano. The method includes detecting at least one of a telomeric breakpoint of an inverted ECA3q chromosome and/or a centromeric breakpoint of an inverted ECA3q chromosome. In one embodiment, the nucleic acid may be analyzed by the steps of hybridizing the group of probes or primers having the sequences set forth herein in SEQ ID NO:8, SEQ ID NO: 9, and SEQ ID NO: 10, or sequences complementary thereto, and preparing an amplification product. A 209 bp nucleic acid amplification product (SEQ ID NO:11) indicates the presence of the inversion. | 07-22-2010 |
Samantha A. Brooks, Van Etten, NY US
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20110265193 | IDENTIFICATION OF MUTATION AND METHOD FOR DETECTING LAVENDER FOAL SYNDROME IN THE HORSE - Provided is a method for determining whether a horse is normal, a carrier, or is affected with Lavender Foal Syndrome (LFS). The method entails, in a biological sample obtained or derived from a horse, determining a single nucleotide deletion which introduces a translational stop codon in the 49 | 10-27-2011 |
Samantha Ann Brooks, Van Etten, NY US
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20120145092 | Identification of the causative mutation for leopard complex spotting & congenital stationary night blindness in equines and a method for testing for same - Methods are provided for determining whether or not a horse is genetically normal, is a carrier of, or is affected with or predisposed to Congenital Stationary Night Blindness and/or leopard complex spotting. The method is based on detection of an insertion in an intron in the horse Transient Receptor Potential Cation Channel, Subfamily M, Member 1 (TRPM1) gene. | 06-14-2012 |