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Brookes
Anthony Joseph Brookes, Leicester GB
| Patent application number | Description | Published |
|---|---|---|
| 20100184153 | High Multiplex Nucleic Acid Amplification - This invention relates to the amplification of multiple nucleic acid target sequences. Forward and reverse compound primers comprising a common amplification sequence and a target-specific primer sequence are immobilised at a site on a solid support. Target regions of single-stranded template DNA are primed and copied by the forward primer to produce a first extension product. The template DNA is removed and the first extension product is primed and copied by the reverse primer to produce a second extension product. The second extension product has common amplification sequences at each end and is bulk-amplified in solution by regular PCR employing primers that target the common amplification sequences. These methods allow highly multiplexed amplifications to be performed. | 07-22-2010 |
Christopher John Brookes, Richmond CA
| Patent application number | Description | Published |
|---|---|---|
| 20110012858 | DUAL SCREEN DISPLAY SYSTEM - A display system is provided with a first display device having a first screen and a second display device having a second screen. The display system also includes a hinging system connecting the first display device and the second display device. The hinging system is configured to permit the second display device to rotate independently of the first display device. | 01-20-2011 |
David Brookes, Mississauga CA
| Patent application number | Description | Published |
|---|---|---|
| 20080308017 | Dual Chamber System for Gasifying Biomass Waste - A device for gasifying biomass waste has two each of primary chambers, fume transfer vents, mixing chambers which accept fumes from the primary chamber, afterburner chambers in fluid communication with the mixing chambers, and an exhaust duct. Each secondary burner produces an initial heating flame within a vertical portion of the respective afterburner chamber, and secondary chambers are in fluid communication with the afterburner chambers. Heated gases from the afterburner chambers cause heating of the secondary chambers. A portion of each primary chamber has a heat conductive floor superimposed over the respective secondary chamber, and the partition between the primary chambers is heat conductive, so that conductive and convective heating of the primary chambers occurs. | 12-18-2008 |
David Frederick Brookes, Birmingham GB
| Patent application number | Description | Published |
|---|---|---|
| 20080291964 | Temperature Sensing - A TGT measurement system comprises a plurality of thermocouples connected in parallel to a distributor, and a data storage device carrying calibration data relating to at least one of the thermocouples. | 11-27-2008 |
David John Brookes, Sutton Coldfield GB
| Patent application number | Description | Published |
|---|---|---|
| 20100329811 | VARIABLE GRIP BLIND RIVET - A variable grip blind rivet includes a tubular rivet body and a mandrel. The rivet body has a first shank, insertable into a hole in a workpiece, and a flange at a first end of the first shank for abutting the workpiece when so inserted. The mandrel has a head, for engaging a second end of the first shank, and a second shank adapted to extend through the axial bore of the rivet body. The head has an abutment portion for abutting the first end of the first shank, and the second shank has a first reduced diameter portion adapted to break when a predetermined tensile is loaded applied. At least one protrusion adjacent the abutment portion defines a recess for receiving the first end of the first shank during setting of the rivet. | 12-30-2010 |
David Patrick Edward Brookes, Oxfordshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20100206055 | Monitoring an Immunoassay - A method of monitoring an immunoassay comprises determining the position of the flow edge of fluid across an immunoassay region. This allows, for example, early detection of possible errors in the test. For example the speed of the movement of the fluid flow edge may be determined from measurements of the position of the fluid flow edge at times throughout the test, and the determined speed may be compared with one or more thresholds to determine whether the test is proceeding correctly. A further method of monitoring an immunoassay comprising monitoring the variation with time of a reference zone of an immunoassay region. This can provide the user with early information as to whether the test is proceeding correctly. The above methods may also be used to provide methods to improve the run conditions of a test during its development. The method may be applied to a competitive assay. | 08-19-2010 |
Graham R Brookes, Carmel, IN US
| Patent application number | Description | Published |
|---|---|---|
| 20080228352 | VEHICLE SUSPENSION SYSTEM AND METHOD OF OPERATING SAME - A suspension system for use on a vehicle having two or more rear axles. The suspension system includes a plurality of gas springs and plurality of height sensors capable of outputting signals having a relation to distances between the respective ends of the respective first and second rear axles and the sprung mass of the vehicle. A control system adapted to selectively inflate or deflate respective ones of the plurality of gas springs to thereby adjust a leveled orientation of the sprung mass. The control system includes a controller that is adapted to determine a rear axle vertical offset and a rear axle articulation offset. The controller is adapted to determine whether conditions are appropriate for adjusting the suspension system by comparing the rear axle vertical offset and/or the rear axle articulation offset to a corresponding vertical offset threshold and/or an articulation offset threshold. A method is also included. | 09-18-2008 |
| 20110115139 | GAS SPRING AND GAS DAMPER ASSEMBLY AND METHOD - A gas spring and gas clamper assembly includes a first end member, a second end member, a first flexible wall that at least partially defines a first spring chamber, and a second flexible wall that at least partially defines a second spring chamber. A damper piston and damper rod are operatively connected between the first and second end members and within the first spring chamber. A suspension system that includes a gas spring and gas damper assembly as well as a method of assembly are also included. | 05-19-2011 |
Jeremy R. Brookes, Lexington, KY US
| Patent application number | Description | Published |
|---|---|---|
| 20080223930 | CASH TRACKING SYSTEM - A system of tracking the location of cash is disclosed. | 09-18-2008 |
Paul Brookes, Worcestershire GB
| Patent application number | Description | Published |
|---|---|---|
| 20110219538 | Support Means for a Patient Handling Hoist - A support device for a patient handling hoist includes two opposed support arms for supporting a harness, each support arm having a harness engagement element. Each support arm is movable between a first working position in which the harness engagement element is a first distance from a central portion of the support device and a plurality of further working positions in which the harness engagement elements of the support arms are a respective plurality of distances from the central portion of the support device. | 09-15-2011 |
Paul Craig Brookes, Southampton GB
| Patent application number | Description | Published |
|---|---|---|
| 20110021037 | COMPOSITION FOR MANUFACTURING SIO2 RESIST LAYERS AND METHOD OF ITS USE - The present invention relates to compositions, which are useful for the generation of patterned or structured SiO | 01-27-2011 |
| 20110227055 | PROCESS FOR THE PREPARATION OF ORGANIC ELECTRONIC DEVICES - The invention relates to the use of a closed field unbalanced magnetron sputter ion plating process in the preparation of organic electronic devices or components thereof, and to organic electronic devices, or components thereof, obtainable by such a process. | 09-22-2011 |
Paul S. Brookes, Rochester, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090149540 | Compositions and Methods for Attenuating Mitochondria-Mediated Cell Injury - The present invention relates to a S-nitrosated mitochondria-targeted thiol-based antioxidant prodrug and uses therefore for the prevention or treatment of diseases or conditions associated with mitochondrial dysfunction resulting from changes in the mitochondrial redox environment. When activated, prodrug of the present invention can specifically provide a NO* donor and a thiol-based antioxidant to mitochondria thereby decreasing the degree of mitochondrial dysfunction. | 06-11-2009 |
Paul Spencer Brookes, Rochester, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100168198 | Mitochondria-targeted antioxidant prodrugs and methods of use - The present invention is a mitochondria-targeted antioxidant prodrug useful for the prevention or treatment of diseases or conditions associated with mitochondrial dysfunction resulting from changes in the mitochondrial redox environment. Antioxidant prodrugs of the invention are produced by modifying an antioxidant to a fatty acid so that the resulting prodrug is targeted to and activated by an enzyme of mitochondrial fatty acid beta-oxidation. | 07-01-2010 |
Roger Brookes, Toronto CA
| Patent application number | Description | Published |
|---|---|---|
| 20100297133 | Immunogenic Polypeptides and Monoclonal Antibodies - Provided herein are compositions and methods for eliciting an immune response against | 11-25-2010 |
| 20110130300 | ASSAY FOR DIAGNOSING STREPTOCOCCUS PNEUMONIAE - Assays for detecting anti-streptococcal antibodies in biological samples using one or more streptococcal antigens are described herein. Various combinations of antigens may be used in the assays. For example, one or more of Ply, PhtD, PhtE, LytB and PcpA may be utilized. Additional streptococcal antigens may also be used. The assays may also be used in combination with assays that detect streptococcal nucleic acids. | 06-02-2011 |
Roger Hamilton Brookes, Toronto GB
| Patent application number | Description | Published |
|---|---|---|
| 20100203568 | Assay Method For Peptide Specific T-Cells - A method of assaying for peptide-specific T-cells comprises adding peptide to a fluid sample of fresh peripheral blood mononuclear cells, and detecting a cytokine such as interferon-γ produced by T-cells that have been pre-sensitised to the peptide. The assay method is quick and cheap and is expected to be useful for the study of various disease states including Hepatitis B, Hepatitis C, tuberculosis, malaria, HIV and influenza. | 08-12-2010 |
Steven Brookes, Mississauga CA
| Patent application number | Description | Published |
|---|---|---|
| 20110104114 | Polysaccharide-Protein Conjugates Reversibly Coupled Via Imine Bonds - A method of preparing an oxidised polysaccharide-protein conjugate by oxidising a polysaccharide with an oxidising agent to form an oxidised polysaccharide and combining such oxidized polysaccharide with a protein. The oxidised polysaccharide is reacted with a protein to form a composition comprising a conjugate wherein the oxidised polysaccharide and the protein are conjugated via one or more imine bonds and wherein the oxidised polysaccharide comprises essentially no alpha-hydroxy aldehyde units. The conjugate may be used to provide sustained or latent activity of the protein. | 05-05-2011 |
Steven J. Brookes, Thetford GB
| Patent application number | Description | Published |
|---|---|---|
| 20110276315 | System and Method for Identifying Under-Defined Geometries Due to Singular Constraint Schemes - Systems, methods, and computer program products for identifying under-defined geometries due to singular constraint schemes. A method includes receiving a CAD model having a plurality of geometries and determining the degrees of freedom for each of the geometries. The method includes identifying a number of constraints on each of the geometries and identifying any of the geometries that are under-defined and any of the geometries that are well-defined. The method includes identifying any of the under-defined geometries that are under-defined due to singular (UDS) and storing a UDS indicator for each of the geometries identified as UDS. The method can include identifying geometries computed from these UDS geometries (CFS) and storing a CFS indicator for each of the geometries identified as CFS. | 11-10-2011 |
Tom Meredydd Brookes, Devon GB
| Patent application number | Description | Published |
|---|---|---|
| 20090299635 | Terrain mapping - A terrain mapping apparatus ( | 12-03-2009 |